Lagenorhynchus albirostris (white-beaked dolphin): 132511763
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Entry
132511763 CDS
T10760
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic isoform X1
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00260
Glycine, serine and threonine metabolism
lalb00630
Glyoxylate and dicarboxylate metabolism
lalb00670
One carbon pool by folate
lalb01100
Metabolic pathways
lalb01200
Carbon metabolism
lalb01230
Biosynthesis of amino acids
lalb01240
Biosynthesis of cofactors
lalb01523
Antifolate resistance
lalb04981
Folate transport and metabolism
Module
lalb_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
132511763 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
132511763 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
132511763 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
132511763 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
132511763 (SHMT1)
Enzymes [BR:
lalb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
132511763 (SHMT1)
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Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Motif
Other DBs
NCBI-GeneID:
132511763
NCBI-ProteinID:
XP_059991313
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Position
20:complement(1506506..1528033)
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AA seq
522 aa
AA seq
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MATPVNGAPVDANLWSSHEKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRKRFSILSAGFTYRVISVNSFTLRTTRSRIHFWFSLQSWY
YGGTEFIDELEVLCQKRALQVYGLDPQGWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD
LPDGGHLTHGFMTNKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT
SCYSRNLDYARLREIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVSTTTHKTLRGC
RAGMIFYRKGVRSVDPKTGRETRYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTP
EFRLYQRQVLANCRALAETLMALGYKVVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI
ACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQIQDTVGVK
ATLKEFTEKLAGAEDHQRAVAALRAEVESFAALFPLPGLPDF
NT seq
1569 nt
NT seq
+upstream
nt +downstream
nt
atggcgactcccgtcaacggagcccccgtggatgccaacttgtggtcctcgcatgagaag
atgctggcgcagcccctgaaagatagcgacgtggaggtttacaacatcattaagaaggag
agtaaccggcagagggtcggcctggagctgatcgcctccgagaactttgccagccgggct
gttctggaggccctgggttcttgcctaaacaacaagtactccgaggggtacccgggccaa
agaaagcgtttcagcattttaagtgctgggtttacctaccgagtgatttccgtcaactcc
ttcaccctgagaaccacaagaagtcgtattcatttctggttttcattacagtcatggtac
tacggcgggacggaattcatcgatgagctggaggtcctctgtcagaagcgagcgctgcag
gtctatggcctggacccccagggctggggagtcaatgtccaaccctactcaggctccccc
gcaaacttcgcggtgtacacagccctggtggagccccacggccgcatcatgggcctggac
ctgcccgacgggggccacctgacccatgggttcatgaccaacaagaagaagatctctgct
acgtccatctttttcgaatctatgccctacaaggtgaaccccgacaccggctacatcaac
tacgaccagctggaggagaatgcccgcctcttccacccgaagctcatcatcgcagggacc
agctgctactcccggaacctggactacgcccggctgcgtgagatcgctgacgacaacggg
gcgtatctcatggccgacatggcacacatcagtgggctggtggcggccggcgtggtgccc
tcccccttcgagcactgccacgtggtgtccaccaccacccacaagaccctgcggggctgc
cgcgccggcatgatcttctacaggaagggagtgcgcagcgtggacccgaagacgggcaga
gagactcgctacaacctggagtcactcatcaactctgctgtgttcccaggcctgcagggg
ggcccccacaaccacgccattgctggggtggcggtggctctgaagcaggccatgactccg
gagttcagactctaccagcgccaggtgctggccaactgcagggctctggccgagaccttg
atggcgctgggctacaaagtggtcacaggtggttctgacaaccacttgatcctcgtggac
ctccgctccaaaggcacagacggcggccgggctgagaaggtgctggaagcctgttccatc
gcctgcaacaagaacacctgcccaggtgacaaaagcgccctgcggcccagcggactgcgc
ctggggaccccggcgctgacatcccgaggactcttggaagaagatttccaaaaagttgcc
cattttattcacagagggatagagctgaccctgcagatccaggacaccgtgggggtgaag
gctaccctgaaggagttcacggagaagctggcaggggccgaggatcatcagcgggctgtg
gcggcactcagggcagaggtggagagcttcgccgccctcttccctctgcccggcctgccc
gacttctag
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