Lagenorhynchus albirostris (white-beaked dolphin): 132516904
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Entry
132516904 CDS
T10760
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00230
Purine metabolism
lalb01100
Metabolic pathways
lalb04927
Cortisol synthesis and secretion
lalb04934
Cushing syndrome
lalb05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132516904 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
132516904 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
132516904 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
132516904 (PDE8B)
Enzymes [BR:
lalb01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
132516904 (PDE8B)
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GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PAS_4
PAS_8
DUF4194
Motif
Other DBs
NCBI-GeneID:
132516904
NCBI-ProteinID:
XP_059999138
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Position
3:60660760..60915199
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AA seq
885 aa
AA seq
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MGCAPSIHVSQSGVIYCRDSDESNSPRQTTSVSQGPAAPLHGLFVQTDAADAIPPSRASW
PPGAARGRRARGELGSGSSAGSTAPAATTCRGRSRHCCSSAEAETQTSYTSVKQVSSAEV
RIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEII
VIDHRQTRNFDAEAVCRSIRATNPSEHTVILAVVSQASGDYEEASVLPLLHAGFNRRFME
NSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEITSDDHVIQYVNPAFER
MMGYHKGELLGKELAELPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVK
ITPVIGQGGKIRHFVSLKKLCCTTDKNKQIHKVHRDSGDNSQTESHSFRHKNRRKESIDV
KSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLE
ILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVPQSHSHLGMPVTI
NDVPPSIAQLLDNEESWEFNIFELEAVTHKRPLVYLGLKVFSRFGVCEFLHCSETTLRAW
LQVIESNYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHP
GRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDSKCNIFKNIDRNHYRTLRQAI
IDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECNPTGKNFPENQILIKRMMIKCA
DVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYF
ITDMFDAWDAFAHLPTLMQHLADNYKHWKTLDDLKCKSLRLPSDS
NT seq
2658 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccacgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccaactcgccccgccagaccaccagcgtgtcgcagggccccgcggccccactg
cacggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcgtcctgg
ccccccggtgccgcccgcggccgcagggcccgcggtgagctgggcagcggcagcagcgcg
ggctccacggcccccgcggcgaccacctgcaggggccggagtcgccactgctgcagcagc
gcggaggccgagacccagaccagctacaccagcgtcaagcaggtctcttctgcagaggta
cgcatcgggcccatgagactgacgcaggatcctatccaggttttgctgatctttgcaaag
gaagacagtcagagtgatggattctggtgggcctgtgacagagccggttacagatgtaat
attgctcggactccggagtcagccctggaatgctttctagataaacatcatgagattatt
gtgatcgaccacagacaaactcgaaactttgatgcagaagcagtgtgcaggtcgatccgg
gccacaaatccctcggagcacacggtgattcttgcagtggtttcacaagcatccggcgac
tatgaagaggcctccgtcctccctcttctgcacgcaggcttcaaccggagatttatggag
aatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagttcgc
tcacagttcaagttaagggcctgtaattcagtgtttacagcattagaccactgtcatgaa
gccatagaaatcacaagcgatgaccacgtgattcagtatgtcaacccagccttcgaaagg
atgatgggctaccacaaaggtgagctcctggggaaagaactcgccgagctgcccaaaagt
gacaagaaccgggcggaccttcttgacaccatcaacacctgcatcaagaagggcaaggag
tggcagggggtttactatgccagacggaaatccggcgacagcatccaacagcatgtgaag
atcactccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaactg
tgttgtaccactgacaaaaataagcagattcacaaggttcatcgtgactcaggagataat
tctcaaacagagtctcattcattcagacacaagaacaggaggaaagagtccattgatgtg
aaatcaatatcatctcgaggcagtgatgcaccaagcctacagaatcgtcgctacccatcc
atggcaaggatccattccatgaccatcgaggctcccatcacaaaggttataaatataatc
aatgcagcccaagaaaacagtcctgtcacagtagcagaagccttggacagagttttagaa
attttacggaccacagaactgtactcccctcagctgggtaccaaagatgaagatccccac
accagtgatctcgtgggaggcctgatgactgatggcttgagaaggttgtcaggaaacgag
tatgtgttcactaagaatgtgccccagagtcacagtcaccttgggatgccggtaaccatc
aacgatgtccccccttctatcgctcaattacttgataatgaggaaagctgggagttcaac
atatttgaattggaagctgtgacacacaaaaggccattggtttacctgggcttaaaagtc
ttttcccggtttggagtatgtgaatttttacactgttctgaaactacccttcgggcctgg
ctccaagtgattgaatccaactaccactcctccaacgcttaccacaactccactcatgcc
gctgatgtcctgcacgccactgccttcttcctcggaaaagaaagagtgaagggaagcctc
gatcagctagatgaggtggctgccctgattgctgccacagtccatgacgtggatcaccca
ggaaggaccaactctttcctgtgcaacgcaggcagtgaactcgccgtgctctataatgac
actgctgtcttggagagtcaccacacagccctggccttccagctcacggtcaaggacagc
aaatgcaacattttcaagaatattgacaggaaccattatcgaacactgcgccaggctatt
attgatatggttttagcaacagagatgacaaaacactttgaacatgtgaacaaatttgtg
aacagcatcaacaagccaatggcagctgagattgaaggcagtgactgtgaatgcaaccct
actgggaagaactttcctgaaaatcaaatcctgattaagcgcatgatgattaagtgtgct
gacgtggccaatccatgccgccccctggacctatgtatcgaatgggctggaaggatctcc
gaggagtactttgcacagactgatgaagagaagagacaggggctacctgtagtgatgcca
gtattcgaccggaatacctgtagcatccccaagtcccagatctcctttattgactacttc
ataacagacatgtttgatgcttgggatgcctttgcacacctgccaaccctgatgcaacat
ttggccgataactacaaacactggaagacgttagatgacctaaagtgcaaaagtctgagg
cttccatctgacagctaa
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