Lagenorhynchus albirostris (white-beaked dolphin): 132517808
Help
Entry
132517808 CDS
T10760
Symbol
DOT1L
Name
(RefSeq) histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1
KO
K11427
[histone H3]-lysine79 N-trimethyltransferase [EC:
2.1.1.360
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00310
Lysine degradation
lalb01100
Metabolic pathways
lalb05202
Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
132517808 (DOT1L)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
132517808 (DOT1L)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
lalb03036
]
132517808 (DOT1L)
Enzymes [BR:
lalb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.360 [histone H3]-lysine79 N-trimethyltransferase
132517808 (DOT1L)
Chromosome and associated proteins [BR:
lalb03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
132517808 (DOT1L)
HMT complexes
Dot1-containing complex
132517808 (DOT1L)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DOT1
HALZ
Motif
Other DBs
NCBI-GeneID:
132517808
NCBI-ProteinID:
XP_060001705
LinkDB
All DBs
Position
3:complement(169754163..169811307)
Genome browser
AA seq
1776 aa
AA seq
DB search
MEAPPPPARTGKGRPSRGAVGLHCIHGLGVRRPWSHPPLSAVVALSLPKACRAPLPEALT
REPTPPPWSRGPMMPRWSRGPMMPWDLCPLPRGPVACSELGSGQRLSPASFSFESMQRLC
DKYNRAIDSIHQLWKGTTQPMKLNTRPSTGLLRHILQQVYNHSVTDPEKLNNYEPFSPEV
YGETSFDLVAQMIDEIKMTEDDLFVDLGSGVGQVVLQVAAATNCKHHYGVEKADIPAKYA
ETMDREFRKWMKWYGKKHAEYTLERGDFLSEEWRERIANTSVIFVNNFAFGPEVDHQLKE
RFANMKEGGRIVSSKPFAPLNFRINSRNLSDIGTIMRVVELSPLKGSVSWTGKPVSYYLH
TIDRTILENYFSSLKNPKLREEQEAARRRQQRENKSNTTTPTKVPESKTAMPADTPMDSG
AEEEKAGATTVKKPSPSKARKKKLNKKGRKMAGRKRGRPKKMSTANPERKPKKTQSALDL
LHAQTVSRAASPSPQGAPYQLPPSTQRRPPEQLLLAPAPPALHRLLESFKIQYLQFLAYT
KTPQYKANLQQLLDQEKEKNARLLGAVQQLFGHCQAQKEEIKRLFQQKLDELGVKALTYN
DLIQAQKEISAHNQQLREQTEQLEKGNRELRSQSLRLLKARCEELKLDWSTLSLEGLLKE
KQALKSQISEKQRHCLELQISIVELEKSQRQQELLQLKSCVPPDDALSLHLRGKGGLGRE
PEAEPGRPHLELDCARFSLPHLSNMSPELSMNGHAAGYELCGALSRPSPKQNTPQYLASP
LDQEVVPCTPNHSGRPRLEKLSGLALPDYTRLSPAKLVLRRHLSQDHTANSRATASELHS
RAEHAKENGLPYQSPGIANGIKLSPQDPRPSSPAALQMTGEKGSEKREQAGPVVCLQGLK
ERTYASSGEAITSLPVSIPLSTVQPSKLPVSIPLASVVLPSRAEKVRSTPSPVPQARESS
STLEKQMGAGTHGSGCNAAGSRSLALAPAGFAYAGSVAISGALAGSPAPLVSGAEPPALD
ESSSSGSLFATVGSRSSTPQHPPLLAQPRNCGSASPAPQLCASPRLGAQGPLPDTSKGDL
PSEAGFSDPESEAKRRIVFTISAGSSSAKQSPSSKHSPLSSGARGDGGQSHGQDSRKRGR
RKRAAAGTPGFSSGVSPKRRALPSVAGLFTQSSGSPLNLNSMVSNINQPLEITAISSPES
SLKSSPVPYQDNDQPPVLKKEKPLSQTNGAHYSPLTSDEEQGSEDEPSSARIERKIATIS
LESKSPPKTLENGGGLAGRKVPASEPVNSSKWKSTFSPISDLGLAKAADSPLQAASALSH
NSLFAFRPGLEEPGAADAKLAAHPRKSFPGALPGAGGLSPSSHPASSFALGGGLAADLSL
HSFSDGASLSHKAPEAAGLGTPLSFPGPRGKEGGAADPGPFVNKRQLDGLAPKGEGGPPV
CGPADKASATHGKAGKGRDREPDVKNGHNLFMAAAAAAAAAAAATPPGGLLSGPGLAPAA
SSAGGTAPSAQTHRPFLGAFAPGPQFALGPMSLQANLGPSVLQSLFSSVPAAGLVHVSTA
ATRLTNSHAMGSFSSGVAGGAVGGAFNHAVPPASAHPFGASFGSGAACRSATLSLTPLQA
VASTPASSFQAPPPAEPRPPPPPPHLGRPPPGPPALHAPPPPNAALPPPPALLPANSEPV
LLQNLASLPANQAFLPASSAASVPPANASLSIKLASLPHKVSRPSFTVHHPPLPGLALAQ
AAPVIPQASSTGPPAVWVSLGMPPPYAARLAGVKPR
NT seq
5331 nt
NT seq
+upstream
nt +downstream
nt
atggaggcccccccacccccggctaggacagggaaggggcggcccagccgtggggcggtg
ggacttcattgcatccacgggttgggggtgaggcggccttggtcccacccgcctctctct
gctgtggtagccctttccctacccaaggcctgcagggcaccgctgcccgaggctttgacc
cgtgagccgacccctccgccctggtctcgaggccccatgatgccacgctggtctcgaggc
cccatgatgccctgggacctctgccccctcccacgaggcccggtggcttgttccgagctc
ggcagtggccagcggctatcacctgcctctttcagcttcgaaagcatgcagaggctctgt
gacaagtacaaccgggccatcgacagcatccaccagctgtggaagggcaccacgcagccc
atgaagctgaacacgcggccatccacggggctcctgcgccacatcctgcagcaggtctac
aaccactcggtgaccgaccccgagaaactcaacaactatgagcccttctccccggaggtg
tacggggagacttccttcgacctggtcgctcagatgatcgacgagatcaagatgaccgaa
gacgacctgtttgtggatctgggtagcggagtgggccaggttgtgctgcaggtcgctgcg
gctaccaactgcaaacatcactatggtgtcgagaaagctgacatcccggccaagtacgcg
gagaccatggaccgagagttcaggaagtggatgaaatggtatggaaaaaagcatgcagaa
tacacactggagagaggagatttcctctcggaggagtggagagagcggatcgccaacacg
agtgttatatttgtgaataactttgcctttggtcctgaggtggatcaccagctgaaggag
cggttcgcaaacatgaaggaaggtggcagaatcgtgtcctcgaagccctttgcacctctg
aacttcagaataaacagtagaaacttgagtgacatcggcaccatcatgcgcgtcgtggag
ctgtcgcctctaaaaggctcggtgtcgtggacggggaagccggtgtcttactacctgcac
accatcgaccgcaccatacttgaaaactatttttctagtctgaaaaatccaaaactcagg
gaggaacaagaggcagctcggcgccggcagcagcgggagaacaagagcaacacgaccacc
cccaccaaggtgcccgagagcaagacggccatgcccgccgacacccccatggactctggt
gctgaggaagagaaagccggggcgaccactgtcaagaagccatctccctccaaggcccgg
aagaagaagctgaacaagaagggccggaagatggccggccggaagcgcggacgtcccaag
aagatgagcaccgccaaccccgagcgcaagcccaagaagacccagagcgcactggacctg
ctgcacgcccagactgtgtcgcgggcggcgtcaccctcgccgcagggcgccccctaccag
ctacctcccagcacgcagcgacgcccccctgagcagctgctgctggcgcccgccccgcct
gccctacaccggctgctagaatccttcaagattcagtacctacagttcctggcgtacaca
aagacccctcagtacaaggccaacctgcagcagctgctggaccaggagaaggagaagaac
gcccggttgctgggcgccgtgcagcagctgttcggccactgccaagctcagaaggaggag
atcaagaggcttttccagcagaaactggatgagctgggagtgaaggcgctgacctacaac
gacctgatccaagcgcagaaggagatctcagctcacaaccagcagctgagggagcagacg
gagcagctggagaagggcaaccgggagctgaggagccagagcctgcggctgctcaaggca
cggtgcgaggagctgaagctggactggtccacgctgtcccttgagggcctgctgaaggag
aagcaggccctgaagagccagatctcggagaagcagaggcactgcctggagctgcagatc
agcattgtggagctggagaagagccagcggcagcaggagctcctgcagctaaagtcctgc
gtgccgcccgacgacgccctgtccctgcacctgcgcgggaagggtggcctgggccgagag
ccggaggccgagcccggccggccacacctggagctggactgtgccaggttctccctgccc
cacttgagcaacatgagcccggagctgtccatgaacggccacgcggccggctatgagctc
tgcggcgcgctgagccggccctcgcccaagcagaacaccccccagtacctggcctccccc
ctggaccaggaggtcgtgccctgcaccccgaaccacagtggccggccgaggctcgagaag
ttgtccggcctggccctgcccgactacaccaggctctccccggccaagctggtgctgcgg
cgccacctgagccaggaccacacagccaacagcagggcgaccgccagcgagctgcactca
cgagctgagcatgccaaggagaacggcctcccgtaccagagccccggcatcgccaacggc
atcaaactgagcccacaggaccctcggccctcgtcccctgcggccttgcagatgacggga
gagaagggcagtgagaagcgggagcaggctggcccggtggtgtgtctgcagggtttgaag
gagcgcacctacgccagcagtggggaggccatcaccagcctgcccgtcagcatcccgctc
agcaccgtgcagcctagcaagctgccagtcagcatccctctggccagcgtggtgctgccc
agccgcgccgagaaggtgagaagcacccccagccccgtgccgcaggcccgagagtcctcg
tccacactggagaagcagatgggtgctggcacccacggctccgggtgcaacgctgctggg
agcagaagcctcgccctggcccccgcaggctttgcctacgccggctcagtggccatcagt
ggggccctggcaggcagcccggcaccactcgtctctggagccgagccccccgccctggac
gagtcctccagctctggaagcctctttgccactgtggggtcccgcagctccacccctcag
cacccccccctgctggcgcagccccgcaactgcggctcggcctcgcccgccccccagctc
tgcgccagtccccggctcggcgcccagggcccgctccccgacaccagcaaaggagacctg
ccctctgaggccggcttctcggatcccgagagtgaagccaagagaaggatcgtcttcacc
atctcggccggctctagcagcgccaagcagtcaccttccagcaagcacagccctctgtcc
tcgggcgcccgcggtgacggcggccagagccacgggcaggacagccgcaagaggggcagg
aggaagcgggcagcggcggggacccccggcttcagctcgggcgtgtcccccaagcgccgg
gccctgccatccgtcgccggcctcttcacccagtcttcagggtcccccctgaacctcaac
tccatggtcagcaacatcaaccagcccttggaaatcacggccatctcgtcccccgagagc
tccctgaagagctcgcctgtcccttaccaggacaacgaccagccgcccgtgctcaagaag
gagaagcccctgagccagaccaacggggcccactattccccgctgacctcggatgaggag
cagggctctgaggacgagcccagcagtgccagaattgagagaaaaattgcaaccatctcc
ttagaaagcaaatctcctccaaaaaccttggaaaatgggggcggcctggcgggaaggaag
gtgccagccagcgagccggtcaacagcagcaagtggaagtccaccttctcgcccatctcc
gacctcggcctggccaaggcagccgacagcccgctgcaggccgcctccgctctgagccac
aactccctgttcgctttccggcccggcctggaggaacctggcgcggctgatgccaagctg
gctgcccaccccaggaagagcttcccaggcgcgctgccgggggcgggcgggctgagcccc
agcagccatcccgccagcagcttcgccctgggcgggggcctggcggccgacctcagttta
cacagcttcagcgatggtgcttctctctcccacaaggcccccgaggcggccggcctgggc
acccccctgagctttcccggcccgcggggcaaggagggcggcgccgcagaccccggcccc
ttcgtgaacaagagacagctggacggactggccccgaagggcgaggggggcccacctgtg
tgcgggcccgcggacaaggcctcagcgacgcacggcaaggcgggcaagggccgtgaccgc
gagcccgacgtcaagaacggccacaacctcttcatggccgctgctgctgctgccgccgcc
gccgccgctgccaccccccccgggggcctcctcagcggcccgggccttgccccggcggcg
tcctcggcagggggcacggccccgtccgcccagacccaccgccccttcctgggcgccttc
gcccccggcccgcagttcgcactgggccccatgtccctgcaggccaacctgggtccgtct
gtgctgcagtccctgttcagctccgtgcccgccgccggcctggtgcacgtctcaaccgcc
gccaccagactgaccaactcgcacgccatgggcagcttctcctccggggtggccggcggt
gcagtcggaggtgcctttaaccacgcggtgcctcccgcctccgctcatccgtttggagcc
agtttcggcagtggggctgcatgtcgcagcgccacgctgagcctaaccccgctgcaggcg
gtggccagcaccccggcctcttcctttcaggccccgccccctgcggagccgaggccgccc
ccgccccctccgcacctgggccggccccctccggggccgcccgccctccacgccccgccc
cctcctaacgccgccttgcctccgccccccgcgctgctcccggctaactctgagcccgtg
ctcctgcagaacctcgcgtccctcccagctaaccaagctttcttacctgcctcctctgct
gcctctgtgccgcctgctaacgcctctctgtccatcaagctcgcctcacttccgcacaag
gtgtcccgcccctccttcacggtgcaccacccgcccctgcccgggctggccctggcccag
gccgcgcccgtgatcccgcaggccagctccacggggccgcccgccgtgtgggtttccctt
ggcatgccacctccgtatgccgcgcgccttgcgggggttaagccgcgataa
DBGET
integrated database retrieval system
