Lagenorhynchus albirostris (white-beaked dolphin): 132521312
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Entry
132521312 CDS
T10760
Symbol
GART
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3 isoform X1
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00230
Purine metabolism
lalb00670
One carbon pool by folate
lalb01100
Metabolic pathways
lalb01523
Antifolate resistance
Module
lalb_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
132521312 (GART)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
132521312 (GART)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
132521312 (GART)
Enzymes [BR:
lalb01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
132521312 (GART)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
132521312 (GART)
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
132521312 (GART)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
GARS_C
AIRS
GARS_N
ATP-grasp
ATP-grasp_3
CPSase_L_D2
ATP-grasp_2
ATP-grasp_4
Dala_Dala_lig_C
LUD_dom
DUF3104
SNF5
Motif
Other DBs
NCBI-GeneID:
132521312
NCBI-ProteinID:
XP_060006840
LinkDB
All DBs
Position
5:complement(134157717..134185453)
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AA seq
1013 aa
AA seq
DB search
MGKRSQPGAGRVGGGRARRIPSADFRRAAGGWAQSAQRGSKCERPESFGSVDISISDHTA
LAQFCKDEKIEFVVVGPEAPLAAGIVGSLTSAGVRCFGPTAEAAQLESSKRFAKEFMDRH
GIPTAQWRAFTKAEEACCFIMSADFPALVVKASGLAAGKGVVVAKSKEEACKAVQEIMQD
KAFGEAGETTVIEELLEGEEVSCLCFTDGKTVAPMPPAQDHKRLLEGDQGPNTGGMGAYC
PAPQVSKDLLLKIKNTILQKTVDGMQQEGVPYTGILYAGIMLTKDGPKVLEFNCRFGDPE
CQVILPLLKSDLYEVIQSTLDGLLCTSLPVWLDNRTAVTVVMASKGYPGDYTKGVEITGF
PEAQALGLEVFQAGTALKDGKVVTNGGRVLTVTAIRENLISALEEAKKGLAAIKFEGAIY
RKDIGYRAIAFLQQPRGLTYKDSGVDIAAGNMLVKKIKPLAKATSRPGCDVDLGGFAGLF
DLKAAGFNDPLLACGTDGVGTKLKIAQQCHKHETIGQDLVAMCVNDILAQGAEPLFFLDY
FSCGKLDPSTAEAVVAGIAKACKKAGCALLGGETAEMPDMYPPGEYDLAGFAVGAMERDQ
KLPHLERITEGDAVIGIASSGLHSNGFSLVRKIVAKSSLQYSSPAPDGCGGQALGDLLLT
PTRIYSHSLLPVLRSGHVKAFAHITGGGLLENIPRVLPQKFGVDLDAQTWRIPRIFSWLQ
QEGHLSEEEMARTFNCGIGAALVVSRDLTQQILQDIQQHKEEAWVIGRVVACPEGSPRVK
VKHLIETMQINRSVLENGTLKNHVSVQPKKARVAVLISGTGSNLQALIDSTREPSSSAHI
VVVISNKAAVSGLDKAERAGIPTRVINHKLYKNRAAFDTTVDQVLEEFSTDIVCLAGFMR
ILSGPFVRKWNGKMLNIHPSLLPSFKGSNAHEQVLDAGVTVTGCTVHFVAEDVDAGQIIL
QEAVPVKRGDTVETLSERVKLAEHKIFPSALQLVASGTVRLGENGKICWVKEE
NT seq
3042 nt
NT seq
+upstream
nt +downstream
nt
atggggaagcgaagccagccgggggcggggcgggtgggcggggggcgtgcgcgccggatc
ccatcggccgacttccggcgcgcggcgggagggtgggctcagagcgcgcagcgagggtct
aagtgcgagcgcccagagagctttgggtccgtggacatctcaatcagtgatcacactgcc
cttgcacagttctgcaaagatgagaaaattgaatttgtagttgttggaccagaggcacct
ctggctgctggaattgttgggagcctgacatctgcaggagtgcggtgctttggccccaca
gcagaagcagctcagttagagtccagcaagaggtttgccaaagagtttatggaccgacat
ggaatcccaactgcacagtggagagctttcaccaaagctgaagaagcctgctgcttcatt
atgagtgcagacttccctgctttggttgtgaaggccagtggtcttgcagctgggaaaggg
gtagttgtcgcaaagagcaaagaagaggcctgcaaagctgtacaggagattatgcaggat
aaagcttttggagaagctggagaaacaactgtcattgaagaacttcttgaaggagaagag
gtgtcttgtctgtgcttcactgatggaaagactgtggcccccatgcccccagcacaggac
cataagcgattgctggagggagatcagggccccaacacagggggaatgggagcctattgt
ccagcgcctcaggtttctaaggatttgttgctaaaaattaaaaatactattcttcagaag
acagtggatggcatgcagcaggagggtgtgccatacacaggtatcctctatgctggtata
atgctgaccaaggatggcccaaaagttctggagtttaattgccgttttggtgatccagag
tgccaagtgatcctcccacttcttaaaagtgacctttatgaagtgattcagtctacctta
gatggcctgctctgcacatctctgcctgtttggcttgacaaccgcactgccgtaactgtg
gtcatggcaagtaaaggttatccaggagactacaccaagggtgtagagataacagggttt
cctgaggctcaagctttaggactagaggtgtttcaagcaggcactgccctaaaagatggc
aaagtggtgactaacgggggtagggtccttacagtaacggccatccgggaaaatctcatc
tcagcccttgaagaagccaagaaaggactagctgctataaagtttgagggggccatttac
aggaaggacattggctatcgtgccatagctttcctccagcagcccaggggcctgacttac
aaggactctggggtagatattgcagctggaaatatgctggtcaagaaaattaagccttta
gcaaaagccacctccagaccaggctgtgatgttgatcttggaggttttgctggtcttttt
gatttgaaagcagccggtttcaacgatcctcttctggcctgtggaacagacggcgttgga
actaaactgaagattgcccagcagtgccataaacatgaaaccattggccaagatttggtt
gcgatgtgtgtaaatgatattctggcacaaggagcggagcccctctttttcctcgattac
ttttcctgtggaaaacttgaccccagtacagctgaagctgttgttgctggaattgctaaa
gcttgtaaaaaagccggatgtgctctcctcggaggtgaaacggcagaaatgcctgacatg
taccctcctggagagtatgatctagccggttttgccgttggtgcaatggagcgggatcag
aaactccctcacctggaaagaatcactgaaggggacgctgttattggaatagcttcatct
ggtcttcacagcaatggatttagccttgtgaggaaaattgtagcgaaatcttcccttcag
tactcctctccagcacctgatggctgtggtggccaggccttaggtgatttacttctaact
ccaaccagaatctacagccattcactgttacctgtcctgcgttcaggacatgttaaggcc
tttgcacatattaccggtgggggattgctagaaaacatccccagagtcctacctcagaaa
tttggggtggatttagatgcccagacctggaggatccccaggatcttctcgtggttacag
caggaaggacacctctctgaagaagagatggccagaacatttaactgtgggattggggct
gccctcgtggtatcaagggatctgacacagcagattctgcaggatattcagcagcacaag
gaagaagcctgggtgatcggcagagtggttgcatgtcctgaaggttctcctcgtgtgaaa
gtcaagcatctgattgaaaccatgcaaataaatagatcagtattggagaatggcaccctg
aaaaatcatgtctctgttcaaccaaaaaaggcaagagtagctgtcttaatatctgggaca
ggatcaaacctccaagctctcatagacagtactagggagccaagtagctctgcacacatt
gttgttgtgatctccaacaaagctgcagtgtctggcttagataaagcagaaagagccgga
attcccaccagggtaattaatcataaattatataaaaatcgtgcagcatttgacactaca
gtagaccaagtccttgaagagttctccacagacatagtctgtcttgcaggattcatgaga
attttatctggcccctttgtcagaaaatggaatgggaaaatgctcaacatccacccatcc
ttgctcccttcgtttaagggttcaaatgcccatgaacaagtcctggatgccggggtcacc
gtcactgggtgcaccgtgcactttgtagctgaagatgtagatgctggacaaattatttta
caagaagctgttccggtgaagaggggtgacactgttgaaactctatctgaaagagtaaaa
ttagcagaacataaaatatttccctcagccctccagctggtggccagtggaactgtacgg
cttggagaaaatggcaagatctgttgggtcaaagaggaatga
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