Lagenorhynchus albirostris (white-beaked dolphin): 132523624
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Entry
132523624 CDS
T10760
Symbol
JAK2
Name
(RefSeq) tyrosine-protein kinase JAK2 isoform X1
KO
K04447
Janus kinase 2 [EC:
2.7.10.2
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb01521
EGFR tyrosine kinase inhibitor resistance
lalb04062
Chemokine signaling pathway
lalb04081
Hormone signaling
lalb04148
Efferocytosis
lalb04151
PI3K-Akt signaling pathway
lalb04217
Necroptosis
lalb04550
Signaling pathways regulating pluripotency of stem cells
lalb04630
JAK-STAT signaling pathway
lalb04658
Th1 and Th2 cell differentiation
lalb04659
Th17 cell differentiation
lalb04725
Cholinergic synapse
lalb04917
Prolactin signaling pathway
lalb04920
Adipocytokine signaling pathway
lalb04933
AGE-RAGE signaling pathway in diabetic complications
lalb04935
Growth hormone synthesis, secretion and action
lalb05140
Leishmaniasis
lalb05145
Toxoplasmosis
lalb05152
Tuberculosis
lalb05161
Hepatitis B
lalb05164
Influenza A
lalb05167
Kaposi sarcoma-associated herpesvirus infection
lalb05168
Herpes simplex virus 1 infection
lalb05200
Pathways in cancer
lalb05207
Chemical carcinogenesis - receptor activation
lalb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
lalb05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
132523624 (JAK2)
04151 PI3K-Akt signaling pathway
132523624 (JAK2)
09133 Signaling molecules and interaction
04081 Hormone signaling
132523624 (JAK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
132523624 (JAK2)
09143 Cell growth and death
04217 Necroptosis
132523624 (JAK2)
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
132523624 (JAK2)
09150 Organismal Systems
09151 Immune system
04658 Th1 and Th2 cell differentiation
132523624 (JAK2)
04659 Th17 cell differentiation
132523624 (JAK2)
04062 Chemokine signaling pathway
132523624 (JAK2)
09152 Endocrine system
04920 Adipocytokine signaling pathway
132523624 (JAK2)
04917 Prolactin signaling pathway
132523624 (JAK2)
04935 Growth hormone synthesis, secretion and action
132523624 (JAK2)
09156 Nervous system
04725 Cholinergic synapse
132523624 (JAK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132523624 (JAK2)
05207 Chemical carcinogenesis - receptor activation
132523624 (JAK2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
132523624 (JAK2)
09172 Infectious disease: viral
05161 Hepatitis B
132523624 (JAK2)
05164 Influenza A
132523624 (JAK2)
05168 Herpes simplex virus 1 infection
132523624 (JAK2)
05167 Kaposi sarcoma-associated herpesvirus infection
132523624 (JAK2)
09171 Infectious disease: bacterial
05152 Tuberculosis
132523624 (JAK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
132523624 (JAK2)
05140 Leishmaniasis
132523624 (JAK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
132523624 (JAK2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
132523624 (JAK2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132523624 (JAK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lalb01001
]
132523624 (JAK2)
Enzymes [BR:
lalb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
132523624 (JAK2)
Protein kinases [BR:
lalb01001
]
Non-receptor tyrosine kinases
JAK family [OT]
132523624 (JAK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
FERM_F2
FERM_F1
SH2_1
Jak1_Phl
SH2
ABC1
FERM_C_FAK1
RIO1
Kinase-like
FERM_M
Motif
Other DBs
NCBI-GeneID:
132523624
NCBI-ProteinID:
XP_060011024
LinkDB
All DBs
Position
7:55450014..55616556
Genome browser
AA seq
1132 aa
AA seq
DB search
MGMACLTMTEMEGTSSSPVHQNGDIPGNANSVKQIDPILQVYLYHSLGKAEGDYLKFPTG
EYVAEEICVAASKACGVTPVYHSMFALMNETERIWYPPNHVFHIDESTRHNVLYRVRFYF
PYWYCNGSNRTYRHGISRGAEAPLLDDFVMSYLFAQWRHDFLHGWIKVPVTHETQEECLG
MAVLDMMRIAKEKDQTPLDIYSSVSYKTFLPKCVRAKIQDYHILTRKRIRYRFRRFIEQF
SHCKATARNLKLKYLINLETLQSAFYTEQFEVKEPGRGPSGEEIFATIIITGNGGIQWSR
GKHKESETLTEQDLQLYCDFPDIIDVSIKQANQEGSNESRIVTIHKQDGKSLEIELMSLR
EALSFVSLIDGYYRLTADAHHYLCKEVAPPMVLENIQSNCHGPISMDFAISKLKKTGNQT
GLYVLRCSPKDFNKYFLTFAVERENVIEYKHCLITKNENGEYNLTGTKKNFSNLKDLLNC
YQMETVRSDSIIFQFTKCCPPKPKDKSNLLVFRTNGISDVPTSPTLQRHNNVNQMVFHKI
RNEDLIFHESLGQGTFTKIFKGVRREVGDYGQLHETEVLLKVLDKAHRNYSESFFEAASM
MSQLSHKHLVLNYGVCVCGEENILVQEFVKFGSLDIYLKKNKNSINILWKLEVAKQLAWA
MHFLEEKTLIHGNVCTKNILLIREEDRKTGNPPFIKLSDPGISITVLPKDILQERIPWVP
PECIENPKNLNLATDKWSFGTTLWEICSGGDKPLSALDSQRKLQFYENRHQLPAPKWTEL
ANLINNCMDYEPDFRPSFRAIIRDLNSLFTPDYELLTENDMLPNMRIGALGFSGAFEDRD
PTQFEERHLKFLQQLGKGNFGSVEMCRYDPLQDNTGEVVAVKKLQHSTEEHLRDFEREIE
ILKSLQHDNIVKYKGVCYSAGRRNLRLIMEYLPYGSLRDYLQKHKERIDHKKLLQYTSQI
CKGMEYLGTKRYIHRDLATRNILVENENRVKIGDFGLTKVLPQGKEYYKVKEPGESPIFW
YAPESLTESKFSVASDVWSFGVVLYELFTYIEKSKSPPAEFMRMIGNDKQGQMIVFHLIE
LLKNNGRLPRPDGCPDEIYVIMTECWNNNVNQRPSFRDLALRVDQIRDSMAG
NT seq
3399 nt
NT seq
+upstream
nt +downstream
nt
atgggaatggcatgccttacaatgacagaaatggaaggaacatcctcatctcctgtacat
caaaatggtgatattcctggaaatgctaattctgtgaagcaaatagatccaatcctacag
gtctatctttatcattcccttggaaaagctgagggggattatctgaagtttccaactgga
gagtatgttgcagaagagatttgtgttgctgcttctaaagcttgtggagtcacacctgtg
tatcatagtatgtttgctttaatgaatgaaacagaaaggatctggtatccacccaaccac
gtcttccatatagatgaatcaaccaggcacaatgtactctacagagtcagattttacttt
ccttactggtattgtaatggcagcaacagaacctataggcatggaatatctcgaggtgct
gaagctcctcttcttgatgactttgtcatgtcttacctttttgctcagtggaggcatgat
tttttgcatggatggataaaagtacctgttactcatgaaacacaggaagaatgtcttggg
atggcggtgttagatatgatgagaatagccaaagaaaaggatcagacccccctggacatc
tatagctctgtcagctacaagacatttttaccaaaatgtgttcgagcaaagatccaagac
tatcatattttgacaaggaagcgaataaggtacagatttcgcagatttattgagcaattc
agccattgcaaagccactgccagaaacttgaaacttaagtatcttataaatctggaaact
cttcagtctgccttctacacagagcaatttgaagtaaaagaacctggaagaggtccttca
ggtgaggagatttttgcaaccattataataactggaaacggtggaattcagtggtcaaga
gggaaacataaagaaagtgagacactgacagaacaggatttacagttatattgtgatttt
cctgatattattgatgtcagtattaaacaagcaaaccaagaaggctcaaatgaaagcaga
attgtaactattcataagcaagatggtaaaagtctagaaattgaacttatgtcattaaga
gaagctttgtcttttgtgtcattaattgatggatattacaggttaactgcagatgcacat
cattatctttgtaaagaagtagcacctccaatggtgcttgaaaatatacaaagcaactgt
catggcccaatttcaatggattttgccatcagtaaactgaagaaaactggtaatcagact
ggactctatgtacttcgatgcagtcctaaggactttaataaatattttctgacttttgct
gttgagagagaaaacgtcattgaatataagcactgtttgattacaaaaaatgagaatgga
gaatacaacctcactggtactaagaagaacttcagtaatcttaaagatcttttgaattgc
tatcagatggaaactgttcgctcagacagtataattttccagtttactaaatgctgtccc
ccaaagccaaaagataaatcaaaccttctagtcttcagaaccaatggtatttctgatgta
ccaacctcaccaacattacagaggcataataatgtgaaccaaatggtgttccacaaaatc
agaaatgaagatctgatatttcatgaaagccttggccaaggaacttttaccaaaattttt
aaaggtgtaagaagagaagtaggagactatggtcaactgcatgaaacagaagttctttta
aaagttctggataaagcacatagaaactattcagagtctttctttgaagcagcaagcatg
atgagccagctttctcacaaacatctggttttaaattatggagtatgtgtctgtggagag
gagaatattctggttcaggagtttgtaaaatttggatcactagatatatatctgaaaaag
aataaaaattctataaatatattatggaaacttgaagtggctaaacagctggcatgggcc
atgcattttctagaagaaaaaacccttattcatgggaatgtgtgcaccaaaaatattctt
cttatcagagaagaagacaggaagacaggaaatcctcctttcatcaaacttagtgatcct
ggcattagtattacagttttgccaaaggacattctgcaggagagaataccatgggtacca
cctgaatgcattgaaaatcctaaaaatctaaatttggcaacagacaaatggagttttggt
accactttgtgggaaatctgcagtggaggagataagcccctgagtgctttggattctcaa
agaaaactacagttttatgaaaataggcaccagcttcctgcaccaaagtggacagaatta
gcaaatcttattaataattgtatggattacgaaccagattttagaccttctttcagagcc
atcatacgagatcttaatagtttgtttactccagattacgaactattaacagaaaatgac
atgttacctaatatgagaataggtgccctagggttttctggtgcttttgaagaccgagac
cctacacaatttgaagagagacacttgaaatttctacagcaacttggcaagggtaatttt
ggcagtgtggagatgtgccggtatgaccctctacaagacaacactggagaggtggtggct
gtgaagaagctccagcacagtactgaagagcacctcagagactttgaaagggaaattgaa
atccttaaatccttgcaacatgacaacattgtaaagtacaagggagtgtgctacagtgct
ggccggcgtaatctaagattaattatggaatatttaccatatggaagtttacgagactat
ctccaaaaacataaagaacggatagatcataaaaaacttcttcagtacacatctcagata
tgcaagggtatggagtatcttggtacaaaaaggtatatccacagggatctggcaacgagg
aatatattggtggagaatgaaaacagagttaaaataggagattttggcttaaccaaagtg
ttgccacaaggcaaagaatactacaaagtgaaagaacctggtgaaagtcccatattctgg
tatgcgccagaatcactgacagagagcaagttttctgtggcctcagatgtttggagcttt
ggagtggttctgtatgaacttttcacatatattgagaagagtaaaagcccaccagcggaa
tttatgcgtatgattggcaatgacaaacaaggacagatgattgtgtttcatttgatagaa
ctcctgaagaataatggaagattaccaagaccagatggatgcccagatgagatttatgta
atcatgacagaatgctggaacaataatgtaaaccaacgcccctctttcagagacctagct
cttcgagttgatcaaataagagacagcatggctggatga
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