Lagenorhynchus albirostris (white-beaked dolphin): 132523918
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Entry
132523918 CDS
T10760
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor isoform X1
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb01521
EGFR tyrosine kinase inhibitor resistance
lalb01522
Endocrine resistance
lalb04010
MAPK signaling pathway
lalb04014
Ras signaling pathway
lalb04015
Rap1 signaling pathway
lalb04066
HIF-1 signaling pathway
lalb04068
FoxO signaling pathway
lalb04081
Hormone signaling
lalb04114
Oocyte meiosis
lalb04140
Autophagy - animal
lalb04144
Endocytosis
lalb04150
mTOR signaling pathway
lalb04151
PI3K-Akt signaling pathway
lalb04152
AMPK signaling pathway
lalb04211
Longevity regulating pathway
lalb04213
Longevity regulating pathway - multiple species
lalb04510
Focal adhesion
lalb04520
Adherens junction
lalb04550
Signaling pathways regulating pluripotency of stem cells
lalb04730
Long-term depression
lalb04913
Ovarian steroidogenesis
lalb04914
Progesterone-mediated oocyte maturation
lalb05200
Pathways in cancer
lalb05202
Transcriptional misregulation in cancer
lalb05205
Proteoglycans in cancer
lalb05214
Glioma
lalb05215
Prostate cancer
lalb05218
Melanoma
lalb05224
Breast cancer
lalb05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132523918 (IGF1R)
04014 Ras signaling pathway
132523918 (IGF1R)
04015 Rap1 signaling pathway
132523918 (IGF1R)
04066 HIF-1 signaling pathway
132523918 (IGF1R)
04068 FoxO signaling pathway
132523918 (IGF1R)
04151 PI3K-Akt signaling pathway
132523918 (IGF1R)
04152 AMPK signaling pathway
132523918 (IGF1R)
04150 mTOR signaling pathway
132523918 (IGF1R)
09133 Signaling molecules and interaction
04081 Hormone signaling
132523918 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
132523918 (IGF1R)
04140 Autophagy - animal
132523918 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
132523918 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
132523918 (IGF1R)
04520 Adherens junction
132523918 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
132523918 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
132523918 (IGF1R)
04914 Progesterone-mediated oocyte maturation
132523918 (IGF1R)
09156 Nervous system
04730 Long-term depression
132523918 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
132523918 (IGF1R)
04213 Longevity regulating pathway - multiple species
132523918 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132523918 (IGF1R)
05202 Transcriptional misregulation in cancer
132523918 (IGF1R)
05205 Proteoglycans in cancer
132523918 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
132523918 (IGF1R)
05214 Glioma
132523918 (IGF1R)
05218 Melanoma
132523918 (IGF1R)
05215 Prostate cancer
132523918 (IGF1R)
05224 Breast cancer
132523918 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132523918 (IGF1R)
01522 Endocrine resistance
132523918 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lalb01001
]
132523918 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lalb04090
]
132523918 (IGF1R)
Enzymes [BR:
lalb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
132523918 (IGF1R)
Protein kinases [BR:
lalb01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
132523918 (IGF1R)
CD molecules [BR:
lalb04090
]
Proteins
132523918 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Ig_DSCAM-DSCAML_C
Kinase-like
Insulin_TMD
Motif
Other DBs
NCBI-GeneID:
132523918
NCBI-ProteinID:
XP_060011792
LinkDB
All DBs
Position
1:143140555..143448739
Genome browser
AA seq
1368 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSTCGKRACTENHECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPSCPPNTYRFEGWRCVDRDFCANIPNAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNRIIITWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDAEPGILLHGLKPWTQYAVYVKAVTLTMVENDHIRGAKSE
ILYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRH
NYCSKADKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYR
KVFENFLHNAIFVPRPERKRREVMQVANTTMSSRNRNTTVVDTYNITDPEELETEYPFFE
SRVDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVT
WEPRPENSIFLKWPEPENPNGLILMYEIKYGSQVEDQRECVSRQEYRKYGGAKLNRLNPG
NYTARIQATSLSGNGSWTDPVFFYVQAKTTYENFIHLIIALPIAVLLIVGGLVIMLYVFH
RKRNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAK
GVVKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIM
ELMTRGDLKSYLRSLRPEMENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAAR
NCMVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFG
VVLWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSF
LEIISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDR
HSGHKAENGPGPGVLVLRASFDERQPYAHMNGGRKKERALPLPQSSTC
NT seq
4107 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctatttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgtgggccaggcatcgacatccgc
aacgactaccagcagctgaagcggctggagaactgcacggtgatcgagggctacctccac
atcctgctcatttccaaggctgaggactaccgcagctaccgcttccccaagctcacggtc
atcactgagtacctgctgctgttccgcgtggccggcctcgagagcctcggtgacctcttc
cccaacctcacagtcatccgtggctggaagctcttctacaactacgccctggtcatcttc
gagatgaccaacctcaaggatattgggctctacaacctgcgaaacattacccgtggggcc
atccggatcgagaagaatgctgacctctgctacctctccacggtggactggtccctaatc
ctggatgccgtgtccaataactacatcgtggggaataagcccccaaaggagtgtggggac
ctgtgcccggggacgatggaggagaagccgctgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggaccacgaaccgctgtcagaaaatgtgcccgagcacgtgcggg
aagcgggcgtgcacggagaaccacgagtgctgccaccccgagtgcctgggcagctgcagc
gcgcctgacaacgacacggcctgcgtggcctgccgccactactactatgccggtgtctgt
gtgcccagctgcccgcccaacacctaccgcttcgagggctggcgttgtgtggaccgtgac
ttctgcgccaacatccccaacgctgagagcagcgattccgagggcttcgtgatccacgac
ggcgagtgcatgcaggagtgcccgtcgggcttcatccgcaacggcagccagagcatgtac
tgcatcccttgcgaaggcccttgtcccaaagtgtgtgaggaagagaaaaagacaaagacc
attgattctgtcacttctgctcagatgctccaaggatgcaccatcttcaagggcaatcta
ctcattaatatccgacgcggcaacaacatcgcttcggaactggagaacttcatgggactc
attgaggtcgtgacgggctacgtgaagatccgccactcccatgccttggtctccttgtcc
ttcctgaagaaccttcgccagatcctaggagaggagcaactagaggggaattactccttc
tacgtcctcgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagccgggaaaatgtactttgctttcaatcccaaattgtgtgtctccgagatttac
cgcatggaggaagtgacggggactaaagggcgccagagcaaaggggacataaacaccagg
aacaatggagagagagcctcctgtgaaagtgacgtcctgcacttcacctccaccaccacg
tggaagaaccgcatcatcatcacctggcatcggtaccggccccctgactacagggacctc
atcagcttcaccgtctactacaaggaagcaccctttaaaaacgtcacagagtatgacggg
caggatgcctgtggctccaacagctggaacatggtagatgtggacctcccacccaacaag
gacgcggagcccggcattttactgcatggactgaagccctggacacagtatgccgtttac
gtcaaggctgtgaccctcaccatggtggagaatgaccacatccgtggagccaagagcgag
atcttgtacattcgcaccaacgcttcagttccttccatccccctggatgtactctcagca
tcaaactcctcttctcagctgatcgtgaagtggaaccctccttccctgcccaacggcaac
ctgagctactacatcgtaaggtggcagcgccagccccaggacagctacctttaccggcat
aattactgctccaaagcagacaaaatccccatcaggaagtacgccgatggcaccatcgac
gttgaggaggtgacggagaatcccaagaccgaagtgtgtggtggggagaaggggccgtgc
tgcgcttgccccaaaaccgaagccgagaagcaggccgagaaggaggaggccgagtaccgc
aaggtcttcgagaatttcctgcacaacgccatcttcgtgcccagacctgaacggaagcgg
agggaggtcatgcaggtcgccaacaccaccatgtccagccggaacaggaacaccacggtg
gtggacacctacaacatcacagacccggaagagctcgagaccgagtaccctttcttcgag
agcagagtggataacaaggagagaactgtcatctccaacctccggccttttactctgtac
cgaatcgatatccacagctgtaaccacgaagctgagaagcttggctgcagtgcctccaac
tttgtctttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccagtgacc
tgggagccaaggcctgagaactccatctttttaaaatggccagaacctgagaatcccaat
ggattgattttaatgtacgaaataaaatatggatcacaagtcgaggatcagcgggaatgt
gtgtccagacaggagtacaggaagtatggaggggccaagctaaaccggctcaacccgggg
aactacacggcccggatccaggccacctctctctctgggaacgggtcgtggactgatcct
gtgttcttctatgtccaggccaaaacaacgtatgaaaacttcatccatctgatcattgct
ctgcccattgccgttctgctgatagtaggagggttggttataatgctgtacgtcttccat
agaaaaagaaataacagcaggctggggaacggagtgctgtatgcctctgtgaacccggag
tacttcagtgcagccgatgtgtacgtgcctgacgagtgggaggtcgcccgggagaagatc
accatgagccgggagctgggacagggctcgttcgggatggtttacgaaggtgtcgccaag
ggcgtggtcaaggatgagcctgagaccagggtggccattaagacggtgaacgaggccgcc
agcatgcgcgagaggattgagtttctcaacgaggcctcggtgatgaaggagttcaactgt
caccacgtggtgcgcttgctgggcgtggtatcccagggccagccgacgctggtcatcatg
gaactgatgacccggggggacctcaaaagttatctccggtctctgaggccagaaatggag
aataatccagtcctagcacctcccagcctaagcaaaatgatccagatggctggagagatt
gcagatggcatggcatacctcaacgccaataagtttgtccacagagacctcgctgcccgg
aactgcatggtggccgaagatttcacagtcaaaatcggagattttgggatgacgagagac
atctatgagaccgactattaccggaagggagggaaggggctgctgcccgtgcgctggatg
tcccccgagtccctcaaggatggagtcttcaccacgcactctgacgtctggtccttcggg
gtcgtcctctgggagatcgccacgctggccgagcagccataccagggcctgtccaatgag
caagtccttcgctttgtcatggagggcggccttctggacaagccggacaactgtcctgac
atgctgtttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttc
ctggaaatcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttc
tactacagcgaggagaacaagccacctgagccagaggagctggacctagagccggagaac
atggagagtgtccccttggacccctcggcatcctcgtcctccctgccactgcccgacaga
cactcaggacacaaggccgagaacggtccgggccctggcgtgctggtccttcgagccagc
ttcgacgagagacagccttatgcgcacatgaacgggggccgcaagaaggagcgggccttg
cctctgccccagtcctcgacctgctga
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