KEGG   Lagenorhynchus albirostris (white-beaked dolphin): 132524865
Entry
132524865         CDS       T10760                                 
Symbol
GCK
Name
(RefSeq) hexokinase-4 isoform X1
  KO
K12407  glucokinase [EC:2.7.1.2]
Organism
lalb  Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00010  Glycolysis / Gluconeogenesis
lalb00052  Galactose metabolism
lalb00500  Starch and sucrose metabolism
lalb00520  Amino sugar and nucleotide sugar metabolism
lalb00524  Neomycin, kanamycin and gentamicin biosynthesis
lalb01100  Metabolic pathways
lalb01200  Carbon metabolism
lalb01250  Biosynthesis of nucleotide sugars
lalb04910  Insulin signaling pathway
lalb04911  Insulin secretion
lalb04917  Prolactin signaling pathway
lalb04922  Glucagon signaling pathway
lalb04930  Type II diabetes mellitus
lalb04950  Maturity onset diabetes of the young
lalb05230  Central carbon metabolism in cancer
Module
lalb_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
lalb_M00549  UDP-Glc biosynthesis, Glc => UDP-Glc
Brite
KEGG Orthology (KO) [BR:lalb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    132524865 (GCK)
   00052 Galactose metabolism
    132524865 (GCK)
   00500 Starch and sucrose metabolism
    132524865 (GCK)
  09107 Glycan biosynthesis and metabolism
   00520 Amino sugar and nucleotide sugar metabolism
    132524865 (GCK)
  09110 Biosynthesis of other secondary metabolites
   00524 Neomycin, kanamycin and gentamicin biosynthesis
    132524865 (GCK)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    132524865 (GCK)
   04910 Insulin signaling pathway
    132524865 (GCK)
   04922 Glucagon signaling pathway
    132524865 (GCK)
   04917 Prolactin signaling pathway
    132524865 (GCK)
 09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    132524865 (GCK)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    132524865 (GCK)
   04950 Maturity onset diabetes of the young
    132524865 (GCK)
Enzymes [BR:lalb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.2  glucokinase
     132524865 (GCK)
SSDB
Motif
Pfam: Hexokinase_2 Hexokinase_1
Other DBs
NCBI-GeneID: 132524865
NCBI-ProteinID: XP_060013365
LinkDB
Position
8:complement(96296781..96352525)
AA seq 537 aa
MLDDRARMEIAKKEKVEQILAEFQLQDEDLKKVMRRMQKEMDRGLRLETHKEASVKMLPT
YVRSTPEGSVYPGVPQMSGIGGPSSSSSGPPTMPSPPPLPVWGLLPGGAHETDVLLSVAA
EVGDFLSLDLGGTNFRVMLVKVGEGEEGQWSVKTKHQMYSIPEDAMTGTAEMLFDYISEC
ISDFLDKHQMKHKKLPLGFTFSFPVRHEDIDKLPSLHACPQHPAATEAPLSPQGILLNWT
KGFKASGAEGNNIVGLLRDAIKRRGDFEMDVVAMVNDTVATMISCYYEDRRCEVGMIVGT
GCNACYMEEMQNVELVEGDEGRMCVNTEWGAFGDSGELDEFLLEYDRVVDENSLNPGQQL
YEKLIGGKYMGELVRLVLLKLVDENLLFHGEASEKLRTRSAFETRFVSQVESDSGDRKQI
YNILSTLGLRPSATDCDIVRRACESVSTRAARMCAAGLAGVINRMRESRSEDVMRITVGV
DGSVYKLHPSFKERFHAGVRRLTPSCEITFIESEEGSGRGAALISAVACKKACMLGQ
NT seq 1614 nt   +upstreamnt  +downstreamnt
atgctggatgacagagccaggatggagatcgccaagaaggaaaaggtggaacagatcctg
gcggagttccagctgcaggacgaggacttgaagaaggtgatgaggcggatgcagaaggag
atggaccgaggcctgaggctggagacacacaaggaggccagtgtgaagatgctgcccacc
tacgtgcgctctaccccggaaggctcagtttatcctggggtcccccagatgtctggcatc
gggggcccctcgtccagctcttctggtccccccaccatgccttcccctcctcctctccca
gtttgggggctcctgcccggcggtgcccatgagactgatgtgcttctctctgtggctgca
gaagtcggggatttcctctccctggacctgggcggcaccaacttcagggtgatgcttgtg
aaggtgggggaaggggaggagggacagtggagtgtgaaaaccaagcaccagatgtactcc
atccccgaggacgccatgacgggcactgctgagatgctctttgactacatctctgagtgc
atctccgacttcctggacaagcatcagatgaagcacaagaagctacccttgggcttcacc
ttctcctttcctgtgaggcacgaagacatcgacaagctcccgtcccttcacgcctgcccc
cagcatccagcagccactgaggcccccctctccccccagggcatccttctcaactggacc
aagggcttcaaggcctcaggagcagaagggaacaacatcgtggggctcctgcgagatgcc
atcaagcggagaggggactttgagatggacgtggtggcgatggtgaacgacactgtggcc
acgatgatctcctgctactatgaagaccgccggtgtgaggttggcatgattgtgggcacg
ggctgcaacgcctgctacatggaggagatgcagaacgtggagctggtggaaggggacgag
ggccgcatgtgtgtcaacaccgagtggggtgccttcggggactcgggcgagctggacgag
ttcctgctggagtacgaccgtgtggtggacgagaattccctgaaccccggccagcagctg
tacgagaagctcatcggcggcaagtacatgggcgagctggtgcggctcgtgctgctgaag
cttgtggacgagaacctgctcttccacggggaggcctcggagaagctgcgcacgcgcagc
gccttcgagacacgcttcgtgtcgcaggtggagagtgactcgggcgaccgcaagcagatc
tacaacatcctgagcacgctggggctgaggccgtcggccaccgactgcgacatcgtgcgc
cgtgcctgcgagagcgtgtccacccgcgccgcgcgcatgtgcgccgcggggctggcgggc
gtcatcaaccgcatgcgcgagagccgcagcgaggacgtgatgcgcatcaccgtgggcgtg
gacggctcagtgtacaagctgcaccccagcttcaaggagcggttccacgccggcgtgcgc
aggctgacgcccagctgtgaaatcaccttcatcgagtcggaggagggcagcggccggggt
gcggccttgatctccgcggtggcctgtaagaaggcctgcatgctgggccagtga

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