Lagenorhynchus albirostris (white-beaked dolphin): 132525635
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Entry
132525635 CDS
T10760
Symbol
IDH2
Name
(RefSeq) isocitrate dehydrogenase [NADP], mitochondrial
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb00020
Citrate cycle (TCA cycle)
lalb00480
Glutathione metabolism
lalb01100
Metabolic pathways
lalb01200
Carbon metabolism
lalb01210
2-Oxocarboxylic acid metabolism
lalb01230
Biosynthesis of amino acids
lalb04146
Peroxisome
lalb05230
Central carbon metabolism in cancer
Module
lalb_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lalb_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
132525635 (IDH2)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
132525635 (IDH2)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
132525635 (IDH2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
132525635 (IDH2)
Enzymes [BR:
lalb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
132525635 (IDH2)
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GFIT
Motif
Pfam:
Iso_dh
Motif
Other DBs
NCBI-GeneID:
132525635
NCBI-ProteinID:
XP_060014619
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All DBs
Position
1:164088238..164105126
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AA seq
452 aa
AA seq
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MAGYLRVVRLLCRASGSGPAWAPAALTAPNLQEQPRRHYADKRIKVAKPVVEMDGDEMTR
IIWQFIKEKLILPHVDVQLKYFDLGLPNRDQTNDQVTIDSALATQKYSVAVKCATITPDE
ARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICRNIPRLVPGWTKPITIGRHAHGDQYK
ATDFVADRAGTFKIVFTPKDGSGAKEWEVYSFPAGGVGMGMYNTDESISGFAHSCFQYAI
QKKWPLYMSTKNTILKAYDGRFKDIFQEIFEKHYRTEFDKNKIWYEHRLIDDMVAQVLKS
SGGFVWACKNYDGDVQSDILAQGFGSLGLMTSVLICPDGKTIEAEAAHGTVTRHYREHQK
GRPTSTNPIASIFAWTRGLEHRGKLDGNQDLIRFAQTLEKVCVETVESGAMTKDLAGCIH
GLSNVKLNEHFLNTSDFLDTIKSNLDKALGQQ
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atggctggttacctgcgggttgtacgcttgctctgtagagcctccggttccgggccggcc
tgggcgccggcagccttaacagcccccaacttgcaagagcagccgcggcgccactatgcc
gacaagaggatcaaggtggcgaagccagtggtggagatggacggcgatgagatgacccgt
attatctggcagttcatcaaggagaagctcatcctgccccatgtggacgtccagctcaag
tattttgacctggggctcccaaaccgtgaccagaccaatgatcaggtcaccatcgactcc
gcgctggccacccagaagtacagcgtggctgtcaagtgtgccaccatcacccctgacgag
gcccgtgtggaagagttcaagctgaagaagatgtggaagagtcccaatggaaccatccgg
aacatcctcggggggactgtcttccgggagcccatcatctgcagaaacatcccacgcctc
gtccctggctggaccaagcccatcaccattggcaggcacgcccacggcgaccagtacaag
gccacagactttgtggctgaccgggccggcacattcaagatcgtcttcaccccaaaggac
ggcagcggagctaaggagtgggaggtgtacagcttccccgccggtggcgtgggcatgggc
atgtacaacacggatgagtccatctcgggttttgcgcacagctgcttccagtatgctatc
cagaagaagtggccactctacatgagcaccaagaacaccattctgaaagcctatgacggg
cgcttcaaggacatcttccaggagatctttgagaagcactacaggaccgagttcgacaag
aataagatctggtacgagcaccgcctcattgacgacatggtggctcaggtcctcaagtct
tcgggcggctttgtgtgggcctgcaagaactacgacggagacgtgcaatcagacatcctg
gcccagggctttggctcccttggcctgatgacgtccgtgctgatctgcccggatgggaag
accattgaggctgaggctgctcatgggacggtcacgcgccactatcgggagcaccagaag
ggccggcctaccagcaccaaccctattgccagcatctttgcctggacgcgtggcctggag
caccgggggaagttggacggaaaccaggacctgatcaggtttgcccagaccctggagaag
gtgtgcgtcgagacagtggagagtggagccatgaccaaggacctggcgggctgcatccat
ggcctcagcaatgtgaagctgaacgagcacttcctgaacacctcggacttcctggacacc
atcaagagcaacctggacaaagctctgggccagcagtag
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