Lagenorhynchus albirostris (white-beaked dolphin): 132529692
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Entry
132529692 CDS
T10760
Symbol
LRRK2
Name
(RefSeq) leucine-rich repeat serine/threonine-protein kinase 2
KO
K08844
leucine-rich repeat kinase 2 [EC:
2.7.11.1
]
Organism
lalb Lagenorhynchus albirostris (white-beaked dolphin)
Pathway
lalb05012
Parkinson disease
lalb05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
lalb00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
132529692 (LRRK2)
05022 Pathways of neurodegeneration - multiple diseases
132529692 (LRRK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lalb01001
]
132529692 (LRRK2)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
lalb04131
]
132529692 (LRRK2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lalb04147
]
132529692 (LRRK2)
Enzymes [BR:
lalb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
132529692 (LRRK2)
Protein kinases [BR:
lalb01001
]
Serine/threonine kinases: TKL group
LRRK family
132529692 (LRRK2)
Membrane trafficking [BR:
lalb04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
132529692 (LRRK2)
Exosome [BR:
lalb04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
132529692 (LRRK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_LRRK2
Beta-prop_LRRK2
ANK_LRRK2
Pkinase
PK_Tyr_Ser-Thr
LRR_8
Roc
LRR_4
COR
Ras
LRR_14
LRR_9
Arf
LRR_13
Beta-prop_EML_2
Beta-prop_RSE1_2nd
T2SSE
Ank_2
WD40_CDC20-Fz
Beta-prop_WDR19_1st
Beta-prop_BBS7
nSTAND3
AAA_22
AAA_16
ABC_tran
PduV-EutP
MMR_HSR1
AAA_7
Beta-prop_RIG_2nd
GTP_EFTU
WD40_Prp19
G-alpha
NACHT
MobB
Kdo
TrwB_AAD_bind
LRR_6
AAA_29
cobW
FtsK_SpoIIIE
TniB
Arm
AAA_23
Motif
Other DBs
NCBI-GeneID:
132529692
NCBI-ProteinID:
XP_060022526
LinkDB
All DBs
Position
11:complement(71759694..71913986)
Genome browser
AA seq
2525 aa
AA seq
DB search
MASGSCQDCEEDEETLKKLIVRLNNVQEGKQIETLVQILEDMLVFTYADHASKLFQDKNV
HVPLLIVLDSYMRVASVQQVGWSLLCKLIEICPNTMQSLMGPQDIGHDWEVLGVHQLILK
MLTVHNASVNLSTVGLKALDLLLTSGKITLLILDEENDIFLLIFDAMRTFSANDEVQKLG
CKALHVLFERVSEEQLTEFVENKDYMILLSTLKHFKDEEEIVFHVLHCLYSLAIPCNNVE
VLMSGNVRCYNIVVEAMIAFPISEKIQEVSCCLLHRLTLGNFFNILVLNEVHVFVVKAVQ
QYSENAALQIAALSCLALLTETIFLNQDLEEKNENQENDDEEDKLFWLEACYKALTWHRK
NKHVQEAACWALNNLLMYQNSLHEKIGDEDGQFPAHREVMLSMLMHSSSKEVFQASANAL
STLLEQNVNFRKILLSKGIYLNVLELMQKHIHSPEVAESGCKMLNHLFEGSNTSLDTMAA
VARKIITVMRSHETSVSVQLEALRAILHFIVPGIPEESREDTEYQHKLSMVKKQCFRNDI
HKLVLAALNRFIGNPGIQKCGLKVISSIAHFPDALEVLSLEDAIDSVLHTLQMYPDDQEI
QCLGLSLIGCLITKKNLCIGTGHLLAKVLISSLQRFKDIGEIQMKGFQTILTVLELSVSF
SKLLVHHSFDSVIFHQLSSNIMEQKDQQFLNLCCKCFAKLAMDDELKSVMLERACDQNNS
IMVECLLLLGADANRAKEAASLICQVCEKASSPKVVELLLNSGSREQDVRKALTISIGKG
DSQIISLLLKRLALDLANNSICLGGFCMGKIEPSWLGPLFPDKTSNLRKETNIGSTLARM
VLRYQMKSAVEEGTASGSSGTFSEEILDKFDEWTFIPESYVDSVFAQSDDLDSEGSEGSF
LVKKKSNSISVGEFYRDPALQRCSPNLQRHSNSLGPMFDHEDLLKRKRKILTSDDSLRAS
KFQSHMKHSESISSLSSEREYITSLDLSANELRDIDALSQKSCISGHLEHLEKLELHQNA
LTSFPQQLCETLKCLTHLDLQSNKFTSFPPYLLKMNCIANLDVSRNDIGPSVVLDRAVRC
STLKQFNLSYNQLSFLPENLGDVVEKLEQLILEGNKISGIYSPLSLKELKILNLSKNHIS
SLSEDFLETCPKVESLSARMNFLAAMPFLPSSMTSLKLSQNRFTCVPEAILNLPHLRSLD
MSNNDIQYLPGPVHWRSLNLRELLFSHNQISILDLSEKACAWSRVEKLHLSHNKLKEIPP
EIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDIIRFL
QQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKIKKSDLGMQGATVGIDVKDWPIQIRG
KGKKDLILNVWDFAGCEEFYSTHPHFMTQRALYLAVYDLSKGQAEVDAMKPWLFNIKARA
SSSPVILVGTHLDVSDEKQRKACISKITKELLNKRGFPAIRDYHFVNATEESDALAKLRK
TIINESLNFKIRDQPVVGQLIPDCYVELEKIILSERKNVPVEFPVIDQKRLLQLVKEHQL
QLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKVMAQILTVKVEGCPKHP
KGIISRRDVEKFLSKKKRFPKNYMSQYFKLLEKFQIALPTGEEYLLVPSSLSDHRPVIEL
PHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRMYWRQGIYLNW
SPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICG
EGETLLKKWALYSFNDGEEHQKILLDNLMKKVEEGDLLVNPDQPRLTVPISQIAPDLILA
DLPRNIMLNNDELEFEQAPEFLLGDGSFGSVYRASYEGEEVAVKIFNKHTSLRLLRQELV
VLCHLHHPSLISLLAAGVRPRMLVMELASKGSLDRLLQQDKASLTRTLQHRIALHVADGL
RYLHSAMIIYRDLKPHNVLLFTLYPNAAIIAKIADYGIAQYCCRMGIKTSEGTPGFRAPE
VARGNVIYNQQADVYSFGLLLYDILTTGGRIAEGLKFPNEFDELAIQGKLPDPVKEYGCA
TWPMVEKLIKKCLKENPQERPTSAQVFDILNSAELICLMRRISIPKNFTVECMVAMNHNS
KNASIWLGCGHTDKGQLSFLDLNTERYTSAEVTDSRILCLALVHLPVEKESWIVSGTQSG
MLLVVNTEDERKRHTLEKMTDSVTCLYCNSFSKQSKQKNFLLVGTADGNLAIFEDKTVKC
KGAAPLKTLNIGNVSTPLMCLSESMNSTEKNIMWGGCGTKVFSFSDDFTIQKRIETRTNQ
LFSYASFSDSNIIAVVVDTALYVAKKNSPFVEVWDKKTEKLCELIDCVHFLKEELVKANK
EAKHQMSYSGRVKTLCLQKNTALWIGTGGGHILLLDLSARRIICIIHSFCDSVRAMMTAQ
LGSLKNVMLVLGYNRKSIEGMQHQKEIQSCLSVWDINLPHEVKNLEKHIGVRKELAEKMR
RISVE
NT seq
7578 nt
NT seq
+upstream
nt +downstream
nt
atggccagtggcagctgccaggactgtgaggaggatgaggaaactctgaagaagttgata
gtcaggctgaacaatgtccaggaaggaaaacagatagagacgctggtccaaatcctggag
gatatgctcgtgttcacttacgccgaccacgcctccaagttatttcaagacaaaaatgtc
cacgtgcctctgttgatcgtcttggactcgtatatgagagtcgctagtgtgcagcaggtg
ggttggtcacttttatgcaaattaatagaaatctgtccaaatacaatgcaaagcttaatg
ggtccccaggatattggacatgattgggaagtcctaggggttcaccaactgattcttaaa
atgctaacagttcataatgccagtgtcaacctgtcaacagttggattgaaggccttagat
cttctcctaacttcaggtaaaatcactttgctgatactggatgaagaaaatgatattttc
ttgttaatttttgatgccatgcgcacattttcagccaatgacgaagtccagaaacttgga
tgcaaagctttacatgtgctgtttgagagagtttcagaggagcaactgactgaatttgtt
gagaataaagattatatgatattgctaagtacattaaaacattttaaagatgaagaggaa
attgtgtttcatgtactgcactgtttatattccctagcaattccttgtaataatgttgaa
gtcctcatgagtggcaatgtcaggtgttataatattgtggtagaagccatgatagcattc
cctatcagtgaaaaaatccaagaagtgagttgctgcttgctccataggcttacattaggt
aatttttttaatattctggtattaaacgaggtgcatgtgtttgtggtgaaagctgtgcag
cagtattcagagaatgcagcattacagattgcagcactcagctgtttagctctcctcact
gagaccattttcttaaatcaagacttagaggaaaagaatgagaatcaggagaatgatgat
gaagaagataaattgttttggctggaagcctgctacaaagcattaacgtggcatagaaag
aacaagcatgtgcaggaggctgcatgttgggccctgaataatctccttatgtaccaaaac
agtttacatgagaagattggagatgaagatggccagttcccagctcacagggaagtgatg
ctctcgatgctgatgcattcttcatcaaaagaagtcttccaggcatctgcaaatgcattg
tcgactctgttagagcaaaatgttaatttcagaaagatcctgttatcaaaaggaatatat
ctgaatgtgttggagttaatgcagaagcatatacattctcctgaagtggctgaaagtggc
tgtaaaatgctaaatcatctttttgaaggaagtaacacttccctggatacaatggcagca
gtggcccgcaaaataataacagttatgagaagtcatgagacgtcagtatcagtgcagctg
gaggcacttcgagctattttacattttatagttccaggcatcccagaagaatccagggaa
gatactgaatatcagcataagctaagtatggttaaaaaacagtgtttcaggaatgatatt
cacaaattggtcctagcggctttgaacaggttcattggaaatcctgggattcagaaatgt
ggattaaaagtaatttcttctatagcacattttcctgatgcattagaggtgttatccctg
gaagatgctattgattcggtgcttcacacactgcagatgtatccagatgaccaagaaatt
cagtgtctgggtttaagtcttataggatgtttgattacaaagaagaatttatgcataggc
actgggcatctgctggcaaaagttctgatttccagcctacaacgatttaaggatattggt
gaaatacagatgaaaggatttcagacaatcttgacggtactggaattgtcagtgtctttt
tccaagctgctggtgcatcattcctttgattcagtaatattccatcagttgtcctccaac
atcatggagcaaaaggatcaacagtttctaaatctttgttgcaagtgctttgcaaaattg
gccatggatgatgagttaaaaagtgtgatgctagagagagcatgtgatcaaaataacagc
atcatggtcgaatgcttgcttctgttgggagcggatgccaatcgagcaaaagaagcagct
tctttaatttgtcaggtatgtgagaaagcgagcagtcccaaagtggtagaactgttactg
aatagtggatcccgtgagcaggatgtacggaaagctctaacaatcagcattgggaaaggc
gacagccaaatcatcagcttactcttaaagaggcttgccctggatctggccaataatagc
atctgccttggaggattttgtatgggaaaaattgaaccttcttggctgggtcctctattt
ccagataagacatctaatttaagaaaagagacaaatataggatccaccctagcgagaatg
gtgctcagatatcagatgaaaagtgctgtggaagaaggaacagcctcaggcagcagtggg
actttttctgaagaaatacttgataaatttgatgaatggaccttcattcctgagtcttat
gttgacagtgtatttgctcaaagtgatgacctggatagtgaaggaagtgaaggctcattt
cttgtgaaaaagaaatcaaattcaattagcgtaggagaattttaccgagatcctgccttg
cagcgttgctcaccaaatttgcaaagacattccaattcattgggacccatgtttgatcat
gaagatttactgaagagaaaaagaaaaatattgacttcagatgattcactcagagcatca
aaattccaatcacatatgaagcattcagagagcatttcttccctgtcttctgagagagaa
tatattacatctttagacctttcagcaaatgaactaagagatattgatgccctgagccag
aaatcctgtataagtggtcatttggagcatcttgaaaagctggaacttcaccagaatgca
ctcacgagctttccacaacaactatgtgaaactctgaagtgtttgacacatttggacctg
caaagtaataaatttacatcatttcccccttacttgttgaaaatgaattgtattgccaac
cttgacgtctctcgaaacgacattggaccctcagtagttttggatcgggctgtgaggtgc
tcaaccttgaaacagtttaacctgtcctacaatcagctatcttttcttcctgagaatctc
ggtgatgtggtagagaaacttgaacagctcattttagaaggaaataaaatatcaggaata
tattcccctttgagcctgaaggaactgaagattttaaaccttagtaaaaaccacatttca
tctctatcagaggactttcttgagacttgtcctaaagtggagagtttaagtgccagaatg
aattttcttgctgctatgccttttttgccttcttccatgacaagcctaaaattatctcaa
aacagatttacatgtgttccagaagcaattttaaatcttccacacctgcggtccttagat
atgagcaacaatgatattcaatatctaccaggtcctgtgcactggagatctttgaactta
agggaactcttgtttagtcataatcagatcagtatcttggacttgagtgaaaaagcatgt
gcatggtctagagtagagaaactacatctttctcataataaactgaaagagattcctcct
gagattggctgtcttgaaaatctgacatctcttgatgttagttacaacttggagctgaga
tcctttcccaatgaaatggggaaattaagcaaaatatgggatcttcctttggatgaactg
catcttaattttgattttaaacacataggatgtaaagccaaagacatcataaggtttctt
caacagcggttaaaaaaagctgtgccctataaccgaatgaaacttatgattgtgggaaat
accgggagtggtaagaccaccttgttgcagcaattaatgaaaatcaagaaatcagatctt
gggatgcaaggtgccacagttggcatagacgtgaaagactggcccatccaaataagaggc
aaagggaagaaagaccttattctaaatgtgtgggattttgcaggttgtgaggaattctac
agcactcacccccactttatgacccaacgagccctgtatcttgctgtctatgacctcagc
aaagggcaagctgaagttgatgccatgaagccttggctcttcaatataaaggctcgtgct
tcttcgtcccctgtgattcttgttgggacacatttggatgtttctgatgagaagcagcgc
aaagcctgtatcagtaaaatcaccaaggagctcttgaacaaacgagggtttcctgcaata
cgggattaccactttgtaaatgccactgaggaatccgatgctttggcaaaacttcggaaa
accatcataaatgagagcctcaatttcaagatccgagatcagcctgttgttgggcagctg
attccagactgctatgtagaacttgagaaaatcattttatcagagcgtaaaaatgtgcca
gttgaatttcctgtaattgaccagaaacgattattacaacttgtgaaagaacatcagctg
cagttagatgaaaatgagcttcctcatgcagttcacttcctaaatgaatcaggggtcctc
cttcattttcaagacccagccttgcagttaagtgacttatattttgtggaacccaagtgg
ctttgtaaagtcatggcccagattttgacagtgaaagtggagggctgtccaaagcatcct
aagggaattatttcacgtagagatgtggaaaaatttctttcaaagaaaaagagatttcca
aagaactacatgtcacagtactttaaactcttagaaaaattccagattgccttgccaaca
ggagaagaatatttgctggttccaagcagtttgtcggaccacagacctgtaatagagctt
ccccattgtgagaactctgaaattatcattcgactgtatgaaatgccttattttccaatg
ggcttttggtcgagattaatcaatcgattacttgaaatttcaccttacatgctttcagga
agagaacgagcacttcgcccaaacagaatgtattggcgacaaggcatctacttgaattgg
tctcctgaagcttattgcttggtaggatctgaagtcttagataatcacccagagagtttc
ttaaaaattacagttccttcttgtagaaaaggctgtattcttttgggccaagttgtggac
cacattgactctctcatggaagagtggtttccagggttattggagattgatatttgtggt
gaaggagaaactctgttgaagaagtgggcattatatagttttaatgatggtgaagaacat
cagaaaatcttacttgacaacttgatgaagaaagtagaagaaggagacctcctagtgaat
ccagaccaaccaaggctcaccgttccaatatctcagattgctcctgacttgattttggct
gacctgcctagaaatattatgttgaataatgatgaattggaatttgaacaagctccagag
tttcttttaggtgacggcagttttggatctgtttatcgagcgtcctatgaaggagaagaa
gtggctgtgaagatttttaataaacatacatcacttagactgttaagacaagagctggtg
gtgctttgccacctccaccatcccagcttaatatctttgctggcagctggggttcgtcct
cgaatgttggtgatggagttagcctccaagggttccctggatcgcctgcttcaacaagac
aaagccagtctcaccagaacgctgcagcacaggattgcactacatgtggctgatggtctg
agatacctccactcagccatgattatataccgtgacttgaagccccacaacgtgttgctt
ttcaccctgtatcccaatgccgccatcattgccaagattgcggactatgggattgctcag
tactgctgtagaatggggataaaaacgtcagagggcacaccagggtttcgtgcacctgaa
gttgccagaggaaatgttatttataaccaacaggctgatgtttattcatttggtttgcta
ctctatgatattttgacaactggaggtagaatagcagagggtttgaagttcccaaatgag
tttgatgaattggcaatacaaggaaaattacctgatccagttaaagaatatggttgtgcg
acatggcctatggttgagaagttaattaaaaaatgtttgaaagaaaatcctcaggaaaga
cctacttctgcccaggtctttgacattttgaattcagctgagttaatctgtctgatgagg
cgtatatcaatacctaaaaactttactgttgaatgtatggttgctatgaatcataacagc
aagaatgcaagcatttggctgggctgtgggcacactgacaaaggacagctctcctttctt
gacttaaatacagaaagatacacttctgcggaagttactgatagtagaatattgtgccta
gccttggtgcatcttcctgttgaaaaggaaagctggattgtatctggaacacagtctggc
atgctcctcgtcgtcaatactgaagatgagagaaagaggcacactcttgaaaagatgact
gattctgttacttgcttgtattgcaattccttttccaagcaaagcaagcagaaaaatttc
cttttagtgggaactgctgatggcaacttagcaatttttgaagataaaacggttaagtgt
aaaggagctgctcctttgaagacactcaatataggaaatgtcagcactccactgatgtgt
ttgagtgaatccatgaattcaaccgagaaaaacattatgtggggaggatgtggtacaaaa
gttttctcattttctgatgatttcaccattcagaaacggattgagaccaggacaaatcag
ctgttttcttatgcatctttcagtgattccaacatcatagcagtggtggtagacacggct
ctttatgttgctaagaaaaatagcccatttgtggaagtatgggacaagaagactgaaaaa
ctctgtgaactgatagactgtgtgcactttttaaaggaggagctggtcaaagcaaacaag
gaagcgaaacaccaaatgtcttattctgggagagtgaaaactctctgcctccagaagaac
actgccctctggatagggactggggggggccatatcttactccttgatctttcagctcgt
cgaatcatctgtataattcacagcttttgtgattctgttagggccatgatgactgcacag
ttaggaagccttaaaaatgtcatgctggttttggggtataaccggaagagtattgaaggt
atgcaacatcaaaaagagatacagtcctgcttgtctgtttgggacatcaatcttccacat
gaagtgaaaaatttagaaaaacatattggagtgagaaaagaattagctgaaaaaatgaga
agaatatctgttgaataa
DBGET
integrated database retrieval system
