Lactiplantibacillus argentoratensis: LPA65_02170
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Entry
LPA65_02170 CDS
T07625
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
larg
Lactiplantibacillus argentoratensis
Pathway
larg00300
Lysine biosynthesis
larg00550
Peptidoglycan biosynthesis
larg01100
Metabolic pathways
larg01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
larg00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LPA65_02170 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LPA65_02170 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LPA65_02170 (murF)
Enzymes [BR:
larg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LPA65_02170 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3323
DUF7639
Motif
Other DBs
NCBI-ProteinID:
AYJ37045
UniProt:
A0AAN1Q499
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All DBs
Position
463104..464492
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AA seq
462 aa
AA seq
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MKMQVAEIAKAVQAVNAEQAWPDVNVTGVAFDSRKLQAGDLFIPLMGANDGHQYIQSAIE
HGAVATLWASDHADDVPEDLPVIMVADTLTALQQLGQYYLQKINPKVVAVTGSNGKTTTK
DMIASVLGTQFNVTKTHANFNNQIGVPVTLLSMEPNTEVVVVEMGMDHFGELDFLSRLVQ
PDVAVITMIGEAHIEFFGTRDRIADAKMEIVHGLKEDGTFIFNGDEPLLQERAKEVSQHQ
RTFGLDDTNTLAGSDITTSRAQTQFKTSLWPDNTYTIPMMGAYNVNNALAALLVADTFHI
RPAAAQQAIASFVPTENRTEWLTGYRGEAILSDVYNSNPTAARRVLAAFAAVPTKGQRIA
VLGDMLELGDQSDALHMSLASELDPATIASVYLNGEHMRALAEVLQEKYPAGAVHYYQTD
QQPQLIADLTAAVGADDQILLKGSHGIHLEKVLTALEAASEK
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaagatgcaagttgccgaaattgctaaggccgttcaagcggtcaatgccgaacaggcg
tggcccgatgttaatgtaacaggtgtggcgtttgatagccgaaagctccaagcaggggat
ctatttattccgctgatgggcgctaatgatggtcatcaatatattcaaagtgcaatcgag
cacggggccgttgctaccttatgggccagcgaccatgccgacgacgttccagaagactta
cctgtcattatggttgctgatacattgacggcactacagcagctggggcaatactattta
caaaaaattaatccgaaagtcgtggctgttacgggtagtaatggtaaaacaacgacgaag
gatatgattgcgagtgttttgggcactcagtttaacgtgacaaagacgcacgccaacttt
aacaatcagattggtgtgccagtgacgttactcagtatggaaccgaatacagaagtggtc
gtcgttgaaatggggatggaccattttggcgagttggatttcttgagccgtctcgttcag
ccggacgttgcggtgattaccatgattggggaagcccacattgagttctttggtacacgg
gatcgaattgctgatgccaaaatggaaattgtccacggcttaaaagaagatggcacgttc
atttttaatggtgatgaaccactgctacaagaacgtgctaaggaagtcagtcagcatcaa
cggacgtttgggttggatgatacgaacaccttagcaggcagtgatatcacgactagtcgg
gctcaaacgcaatttaagacgagtctgtggccggacaacacgtacacaattccgatgatg
ggtgcgtacaatgtcaataatgcattggcggcgctcttggtagctgatacttttcacatt
cgaccagccgctgcacaacaagcaatcgccagttttgtgccgacggagaaccggacggaa
tggttaactggttaccgtggagaagccatcttaagtgatgtttataactctaatccaacg
gcagctcgacgggtcctagccgcttttgcggcggtacctactaagggtcagcgaatcgct
gtactcggtgatatgcttgagttgggtgaccagtcggatgcactacacatgagtttagcc
agtgaattggatccagccacgattgccagcgtctatttgaatggtgagcatatgcgagcg
ttggcagaagtgctacaagaaaagtaccccgccggtgcggttcactactatcaaacagat
cagcaaccccaattgattgctgacttaaccgcggcagttggtgcggacgatcagatctta
ttgaaggggagtcacgggattcatcttgaaaaagttctgacggcactagaagctgcttct
gaaaaataa
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