Lysobacter auxotrophicus: LA521A_32010
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Entry
LA521A_32010 CDS
T09075
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
laux
Lysobacter auxotrophicus
Pathway
laux00260
Glycine, serine and threonine metabolism
laux00261
Monobactam biosynthesis
laux00270
Cysteine and methionine metabolism
laux00300
Lysine biosynthesis
laux01100
Metabolic pathways
laux01110
Biosynthesis of secondary metabolites
laux01120
Microbial metabolism in diverse environments
laux01230
Biosynthesis of amino acids
Module
laux_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
laux_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
laux00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
LA521A_32010 (thrA)
00270 Cysteine and methionine metabolism
LA521A_32010 (thrA)
00300 Lysine biosynthesis
LA521A_32010 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
LA521A_32010 (thrA)
Enzymes [BR:
laux01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
LA521A_32010 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
LA521A_32010 (thrA)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
ACT_7
NAD_binding_3
ACT
LytR_C
Motif
Other DBs
NCBI-ProteinID:
BDU18000
UniProt:
A0ABM8DHB1
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All DBs
Position
3590583..3593120
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AA seq
845 aa
AA seq
DB search
MPPADASHPSAPPCHVHKFGGSSLADAPLYRAAAALVDDPSRTRVVVVSAMQGVTDALIA
LLDTAQRGDAWQPAFDALRERHLVAAEALDPDGHFDLRARLEEEFATLRHQLQAIAGGEP
DAAQLAPGLPGFGEVFSSFLMHAALGGDAASWRRLDARDVLVVHEGEMGMAVDWPQSRAR
LAQWRAAQGDGNVVITGFVARDTHGRATTLGRNGSDYSAAIFANLFDAAALTIWTDVDGV
LSADPRLVPEAVCLPSMSYAEACELAYFGAKVLHPQTMAPVQERGIPLWIRNTKRPEAPG
TLIAPDSGRDGAPVKGLSLVRDLAIVELVGNGMVGVPGAAERLFGALRGAGVSVTMISQG
SSEHSICCVLRADQAERARDAAAAAFADAIADGQAQGVTLTRDIAVLAAVGDGMVGTPGV
AARLLGGLAQARVNARAIAQGAGERNISVAIGANDATRALRAAHAAFWLSPQTLSVGVIG
PGQVGSALLVQMSAALPQLRERSGLDLRLRAIANSRAMVLDERGVEPVDAVARLHGGAAQ
PLDLDRFADHVRGEHLPHALIVDCSASPRVAAEYPRWLARGIHVVTPNKQAGSGAWDHYA
AIQDASRRGGGRFRYEATVGAGLPVMLTLRNLLDTGDELHGIDGMLSGTLAWLFNRFDGS
VPFSQLVREAQALGYTEPDPRDDLSGLDVARKLVILAREAGRALSLEDVDVENLVPPALR
DVDREEFLARLSEMDEPMLARQRDAAREGRSLRHLAQLDRDGLARVGVVALPAEHACCHT
RLTDNLVQFRTRRYSDNPLVVQGPGAGPDVTAAGVFGDVLAIAQSLGAAASWSSPAIDVR
AQVHA
NT seq
2538 nt
NT seq
+upstream
nt +downstream
nt
atgccgcccgccgatgcgtcccacccttccgctccgccgtgccacgtgcacaagttcggc
ggcagcagcctcgccgatgccccgctctatcgcgccgccgcggcgctggtcgatgacccg
tcccgaacgcgcgtcgtcgtcgtatcggcgatgcagggcgtcaccgatgcgctgatcgcc
ctgctggacaccgcgcagcgaggcgacgcctggcagcccgccttcgatgccttgcgcgaa
cgccatctcgtggcggccgaagcgctcgatcccgacggccacttcgatctgcgcgcccgg
ctggaagaggaattcgcgacgcttcgccaccaactccaggcgattgccgggggcgagccc
gacgccgcgcagctcgcgcccgggctgcccggtttcggcgaagtgttctcgtccttcctg
atgcacgccgcgctcggcggcgacgccgcgtcgtggcgccggctcgatgcgcgcgacgtc
ctggtcgtgcacgaaggcgagatgggcatggccgtcgactggccgcaaagccgcgcgcgc
ctcgcgcaatggcgggcggcgcagggcgatggcaacgtggtgatcaccggcttcgtcgcg
cgcgacacgcacggccgcgcgacgacgctgggccgcaacggcagcgactactccgccgcg
atcttcgccaacctgttcgatgccgccgcgctcacgatctggaccgacgtggacggcgtg
ctgtcggcggacccgcgcctggtaccggaagccgtgtgcctgccgtcgatgtcctacgcc
gaagcctgcgagctggcctacttcggcgcgaaggtgctgcatccgcagaccatggcgccg
gtgcaggaacgcggcatcccgctgtggatccgcaacacgaagcggcccgaagcgcccggc
acgctgatcgcgcccgacagcggccgcgatggcgcgccggtgaaaggcttgagcctggtg
cgcgacctcgccatcgtcgaactcgtcggcaacggcatggtcggcgtgcccggcgcggcc
gagcgcctgttcggcgcactgcgcggcgcgggcgtctcggtgacgatgatctcgcagggc
tcgtccgaacattcgatctgctgcgtgctgcgcgccgaccaggccgaacgcgcgcgcgac
gcggccgctgccgcgttcgccgacgccatcgccgacggccaggcgcagggcgtgacgctc
acacgcgacatcgcggtgctcgcagccgtcggcgacggcatggtcggcacaccgggcgtc
gcggcgcgactgctcggcggactcgcacaggcgcgcgtgaatgcccgggcgatcgcgcag
ggtgcgggcgaacgcaacatctcagtcgccatcggcgcgaacgacgccacccgcgcattg
cgcgccgcgcacgcggcgttctggttgtcgccgcagacgttgtcggtcggcgtgatcggg
cccggccaggtcggcagcgcgttgctggtccagatgtcggcggcattgccgcagctgcgc
gagcggtccgggctggacctgcgcctgcgcgccatcgccaacagccgcgcgatggtgctg
gacgaacgcggcgtggagccggtcgatgccgtcgcgcgcctgcacggcggggcggcgcaa
ccgctcgacctggaccgcttcgccgaccacgtacgcggcgagcatcttccgcatgcgctc
atcgtcgattgcagcgcgagcccccgcgtggcggcggagtatccgcgctggctcgcgcgc
ggcatccacgtggtcacgccgaacaagcaggccggcagcggcgcgtgggatcattacgcc
gccatccaggacgcgagccgtcgcggcggtgggcgcttccgctacgaggcgaccgtcggc
gccggcctcccggtgatgctgacgctgcgcaacctgctcgacacgggcgacgagctgcac
ggcatcgacggcatgctctcgggcacgctggcctggctgttcaaccggttcgacggctcg
gtgccgttctcgcagctcgtccgcgaggcgcaggcgctgggctacaccgaaccggacccg
cgcgacgatctgtccggcctcgacgtcgcgcgaaaactcgtgatcctggcgcgcgaagcc
ggtcgtgcgctgtcgttggaggatgtggacgtggaaaacctggtgccgccggcactgcgc
gacgtggaccgcgaggaattcctcgcgcgactgtccgaaatggacgagccgatgctcgcg
cgacaacgcgacgcggcgcgcgaaggccgttcgctgcggcacctcgcgcagctcgatcgc
gatggcctcgcgcgcgtgggcgtggtcgcgttgcccgccgaacacgcctgttgccacacg
cgactgaccgacaacctcgtgcagttccgcacgcgccgctactccgacaatcccctcgtc
gtacagggccccggcgccggccccgacgtcaccgccgccggcgtgttcggcgacgtgctg
gcgatcgcgcaatcgcttggcgcagcggcgtcgtggtcgtcgcccgcgatcgacgtccgc
gcgcaggtccacgcatga
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