Loxodonta africana (African savanna elephant): 100655614
Help
Entry
100655614 CDS
T04351
Symbol
ATIC
Name
(RefSeq) bifunctional purine biosynthesis protein PURH
KO
K00602
phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:
2.1.2.3
3.5.4.10
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00230
Purine metabolism
lav00670
One carbon pool by folate
lav01100
Metabolic pathways
lav01523
Antifolate resistance
Module
lav_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100655614 (ATIC)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100655614 (ATIC)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100655614 (ATIC)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lav04147
]
100655614 (ATIC)
Enzymes [BR:
lav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.3 phosphoribosylaminoimidazolecarboxamide formyltransferase
100655614 (ATIC)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.10 IMP cyclohydrolase
100655614 (ATIC)
Exosome [BR:
lav04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100655614 (ATIC)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AICARFT_IMPCHas
MGS
Ribosomal_L12_N
Motif
Other DBs
NCBI-GeneID:
100655614
NCBI-ProteinID:
XP_010600435
LinkDB
All DBs
Position
Unknown
AA seq
591 aa
AA seq
DB search
MFSVAALFSVSDKTGLVEFARNLTSVGLNLVASGGTAKALRDAGLTVRDVSELTGFPEML
GGRVKTLHPAVHAGILARNIPEDNADMARLDFDLIRVVVCNLYPFVKTVASPDVTVEAAV
EQIDIGGVTLLRAAAKNHARVTVVCDPEDYAAVSAEMQSSNSRDTSLEARRQLALKAFTH
TAQYDEAISDYFRKQYSKGVSQMPLRYGMNPHQTPAQLYTLKPKLPITVLNGAPGFINLC
DALNAWQLVKELKEALGVPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISA
AYARARGADRMSSFGDFIALSDVCDVPTAKIISREVSDGIVAPGYEEEALKILSKKKNEN
YCVLQMDQTYKPDENEVRTLFGLRLSQKRNNGVIDRSLFSNVVTKNKELPESALRDLIVA
TIAVKYTQSNSVCYAKNGQVIGIGAGQQSRIHCTRLAGDKANYWWLRHHPRVLSMKFKTG
VKRAEISNAIDQYVTGTIGEDEDLVKWKALFEEVPELLTEAEKKDWIGKLSEVSVSSDAF
FPFRDNVDRAKRSGVAYIAAPSGSAADQVVIEACDELGIILVHTSLRLFHH
NT seq
1776 nt
NT seq
+upstream
nt +downstream
nt
atgttttctgttgcagcgttatttagtgtctcagacaaaactggccttgtggaatttgcc
agaaacctaacttctgttggtttgaatctggttgcttctggaggcactgcaaaagctctg
agggatgccggtctgacagtcagagatgtctctgagctgacagggtttcctgagatgtta
gggggacgtgtgaaaaccctacatcccgcagtccatgcaggaatcttggctcgtaatatc
ccagaagataatgctgacatggccagacttgatttcgatcttataagagttgttgtttgt
aatctgtacccgtttgttaagactgtggcttctccagatgtaactgttgaggcagctgtt
gagcaaattgatattggtggagtaactttactgagagcggcagccaaaaaccacgctcgc
gtgacagtagtgtgtgacccagaagactacgcggcggtgtctgcagagatgcagagttcc
aatagtagagacacctctttggaggctagacgccagttagccttgaaggcattcactcat
acggcacaatatgatgaagcaatttcagattacttcagaaagcagtatagtaaaggagta
tctcagatgcccttgaggtacggaatgaaccctcatcaaacgccagcccagttatacaca
ctgaagcccaagcttcccatcacagttctaaatggagcccctggatttataaacttgtgc
gatgctttgaatgcctggcagctggtaaaggaactcaaagaagctttaggagttccagct
gccgcctctttcaaacatgtcagtccagcaggcgctgctgttggaattccactcagtgaa
gatgaggccaaagtctgcatggtctacgatctgtacaaaacccttacacccatatcagct
gcatatgctagagcaaggggggccgataggatgtcttcatttggtgattttattgcatta
tctgatgtttgtgatgtccctactgccaaaattatctccagagaggtttctgatggtatt
gttgctccaggatatgaagaagaagccttgaaaatcctttctaaaaagaaaaatgaaaac
tactgtgttcttcagatggaccagacgtacaaaccagatgaaaatgaagttcgaactctt
tttggtcttcgtttaagccagaaaaggaataatggtgtcattgacaggtcattatttagc
aatgttgttaccaagaataaagagttgccggagtctgctctcagggacctcatcgtcgcc
accattgcagtcaagtacactcagtcaaattctgtatgctatgccaagaacggtcaggtt
attggcattggagcaggacagcagtctcggatacactgtacacgccttgcaggggataaa
gcaaactattggtggcttagacatcacccacgcgtgctttcaatgaagtttaaaacggga
gtgaaaagggcagaaatctcgaatgccatcgatcaatacgttacgggaaccattggcgag
gatgaagatttagtaaagtggaaggcactgttcgaggaagtccctgaactattaacggag
gcagagaagaaagattggattggcaaacttagcgaagtttctgtcagttctgatgccttc
tttcctttcagggataatgtggacagagctaaaaggagtggcgtggcgtacattgctgct
ccctccggttctgctgccgaccaagtggtgattgaggcgtgcgatgagctggggataatc
ctcgttcataccagtcttcggcttttccatcactga
DBGET
integrated database retrieval system
