Loxodonta africana (African savanna elephant): 100656270
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Entry
100656270 CDS
T04351
Symbol
PDE3A
Name
(RefSeq) cGMP-inhibited 3',5'-cyclic phosphodiesterase A
KO
K19021
cGMP-inhibited 3',5'-cyclic phosphodiesterase A [EC:
3.1.4.17
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00230
Purine metabolism
lav01100
Metabolic pathways
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04924
Renin secretion
lav05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100656270 (PDE3A)
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100656270 (PDE3A)
04022 cGMP-PKG signaling pathway
100656270 (PDE3A)
09150 Organismal Systems
09152 Endocrine system
04924 Renin secretion
100656270 (PDE3A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100656270 (PDE3A)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100656270 (PDE3A)
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Paralog
GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
100656270
NCBI-ProteinID:
XP_003405726
LinkDB
All DBs
Position
Unknown
AA seq
1141 aa
AA seq
DB search
MAVPGEAARVRDKPSHGGAIPAPAAGPDCHGRAGPASPLDSGCCGCWGDLVLQPLRRSRK
LSSALCAGSLSFLLALLVRLVRGEIGCDLEQSSEEAAVEEAARGAGGGVFPGPRGGAPGG
GAPLSPWLQPSALLFSLLCAFFWMGLYLLRAGVSLPLAVALLAACCGGEALVQIGLGVGE
DHLLSLPAAGVVLSCLAAATWLVLKLRLGVLMIALTSAVRTVSLISLERFKVAWRPYLAY
LAGVLGILLARYVEQILPQSAGATPREHFGSQLIAGTKEDIPVFKRRRRSSSVVSAEMSG
CSSKSHRRTSLPCIPREQLMGHSEWDHKRGQRGSQSSGTSITVDIAVMGEAHGLITDLLA
DPSLPPNVCTSLRAVSNLLSTQLTFQAIHKPRVNPVISFSENYTCSDSEESSEKDKLAIP
KRLRRSLPPGLLRRVSSTWTTTTSATGLPTLEPAPVRRDRSASIKLHEAPLSSAVNPDSW
NNPVMMTLTKSRSFTSSYTVSAANHVKAKKQNRPDALAKISPLSSPCSSPIQGTPASSPI
SKTSAVQFPESAETTAKQGLSSHRALTYYTQSAPDLAPQILTTPVICSSCGRAYSHGNPA
DGPLERGRTTLRTPSRTDDTAQVTSDYETNNNSDSSDIVQNEDETECSRESLRKVSACST
YTPETMIFLDKPILAPEPLVMDNLDSIMEQLNTWNFPIFDLMEKIGRKCGCILSQVSYRL
FEDMGLFEAFKIPIREFMNYFHALEIGYRDIPYHNRIHATDVLHAVWYLTTQPIPGLSTV
INDHGSTSDSDSDSGFTHGHMGYVFSKMYGVPDDKYGCLSGNIPALELMALYVAAAMHDY
DHPGRTNAFLVATSAPQAVLYNDRSVLENHHAAAAWNLFMSRPEYNFLVNLDHVEFKHFR
FLVIEAILATDLKKHFDFVAKFNAKVNDDVGIDWTNENDRLLVCQMCIKLADINGPAKCK
ELHLQWTEGIVNEFYEQGDEEASLGLPISPFMDRSAPQLANLQESFISHIVGPLCNSYDS
AGLMPGKWVEDSDESGDTDDPEEEEGEAPTEEETCENNESPRKKTFKRRKIYCQITQHLL
QNHKMWKKVIEEEQRLAGMEKQSLDQCPQPHSSELIQAIREEEEEKGKQRAEEIPTPKPN
Q
NT seq
3426 nt
NT seq
+upstream
nt +downstream
nt
atggcagtgcctggcgaggccgcccgagtcagggacaagcccagccacggtggggcgatt
ccagcccccgcggccggcccagactgccacggtcgtgcgggccccgcgtcgccgctggac
tcgggctgctgcggctgctggggagacctggtgctgcagccgctccggcgctccaggaaa
ctttcctccgctctgtgcgcgggctccctgtcctttctcttggcgctcctggtgaggctg
gtccgcggggagatcggctgtgacctggagcagagtagtgaggaggcggccgtggaggaa
gcggcccggggagcaggagggggcgtcttcccagggcctcggggaggtgctcccgggggc
ggcgcgccgctcagcccctggctgcagccctcggcgctgctcttcagtctcctgtgtgcc
ttcttctggatgggcttgtacctcctgcgcgctggggtaagcctgcctctggccgtggcg
ctgctggccgcctgctgcgggggagaagcgctcgtccagattgggctgggcgtcggggag
gatcacttactctcgctccccgccgcgggggtggtgctcagctgtttggccgccgcgaca
tggctggtgctgaagctgaggctgggcgtcctcatgatcgccttgactagcgcggtcagg
accgtgtctctcatttccttagagaggttcaaggtcgcctggagaccttacctggcgtac
ttggcaggcgtactggggatcctcctggccaggtacgtggagcaaatcttgccgcagtct
gcgggggcgactccgagggaacattttgggtcccagctgattgctgggaccaaggaagat
atcccggtgtttaagaggaggaggcggtccagctccgtggtgtccgccgagatgtcgggc
tgcagcagcaagtcgcataggaggacctccctaccttgcataccgagagaacagctcatg
gggcattcggaatgggaccataagcgagggcaaagaggatcccagtcttcaggaaccagt
attactgtggatattgccgtgatgggcgaggctcacggtctcattaccgaccttctagca
gacccttctctgcccccaaacgtgtgcacatccttgagggcagtgagcaacctacttagc
acacagctcaccttccaggccattcacaagcccagagtgaaccccgtcatttccttcagt
gagaactatacctgttccgattctgaagaaagttctgaaaaagacaagctggctattccc
aagcgcctgagaaggagtttgcccccaggattgttgagacgagtttcatctacttggaca
accaccacctcagccacaggtctacccaccttagaacctgcaccagttcgaagggaccgt
agcgccagcatcaaactgcatgaagcacctttatccagtgcggtgaatcctgattcttgg
aataacccagtgatgatgaccctcaccaaaagcagatccttcacgtcttcctatactgtt
tctgcagctaatcatgtaaaggctaaaaagcaaaatcgaccagatgccctagcaaagatt
tcacctctctcatcgccctgttcctcacctatccaagggactcctgccagcagcccgatc
agcaaaacttctgcagtgcagttccctgaatctgcagaaacaactgctaaacaaggccta
agttctcacagggctttaacttactatactcagagtgcccctgacctagcccctcagatc
ctgactacaccagttatatgtagcagctgtggcagagcatattcccatgggaatccagct
gatgggccactggagagaggcagaacgacccttcggacaccaagcagaacggatgacaca
gctcaagttacctctgactatgaaaccaataacaacagtgacagcagtgatattgtacag
aatgaagatgagactgagtgttccagagagtcactgaggaaagtgtcagcttgcagcacc
tacaccccggagaccatgatatttctggacaaaccaattcttgctcctgaacctcttgtc
atggataacctggactcaattatggaacagctaaatacttggaattttccaatttttgat
ttgatggaaaagataggaagaaaatgtggctgtattcttagtcaggtatcatacagactt
tttgaagacatgggtctgtttgaagcttttaaaattccaattagggaatttatgaattac
tttcatgctttggagattggctatagggatattccctaccataacagaatccatgccact
gacgtcttacatgcagtttggtatcttactacacaacctattccaggactctccactgtg
attaatgatcatgggtcaacaagtgattcagattctgacagtggatttacacatggacat
atgggatatgtattctcaaaaatgtatggtgtgccagatgataaatatggatgtctgtct
gggaatatccctgccttagagttgatggcactgtatgtggctgctgccatgcatgattac
gatcatccaggaaggactaatgcctttctggttgcaactagtgctcctcaggcggtgcta
tacaacgaccgttcagttttggagaatcaccatgcagctgctgcgtggaatcttttcatg
tcccggccagagtataacttcttagttaaccttgaccatgtggaatttaagcatttccgt
ttccttgtcattgaagcgattttggccacagacctgaagaaacactttgacttcgttgcc
aaatttaatgccaaggtaaatgacgatgttggaatagattggaccaatgaaaatgatcgt
ctcctggtttgtcaaatgtgtataaagttggctgatatcaatggaccagctaaatgtaag
gaactccatcttcagtggacagagggcattgtcaatgaattttatgagcagggtgatgaa
gaggccagtcttgggctaccaataagccccttcatggaccgctctgctcctcagttggcc
aatcttcaggaatccttcatctctcacattgtgggtcctctgtgcaactcctatgactca
gcaggtctcatgccagggaagtgggtggaagacagtgatgagtcaggagatactgatgac
ccagaggaagaagaaggggaagcaccaactgaagaggaaacctgtgaaaataatgaatct
ccaagaaagaaaactttcaaaaggaggaaaatctactgccaaataactcagcacctcctg
cagaaccacaagatgtggaagaaggtcatagaagaggaacagcggttggcaggcatggaa
aagcaatccctggaccagtgccctcagccgcactcctcagaactgatccaggccatcagg
gaagaagaggaagagaaaggaaagcagagagcagaggagatcccaaccccaaagccaaac
cagtga
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