Loxodonta africana (African savanna elephant): 100657418
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Entry
100657418 CDS
T04351
Symbol
ROCK1
Name
(RefSeq) rho-associated protein kinase 1 isoform X1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04062
Chemokine signaling pathway
lav04071
Sphingolipid signaling pathway
lav04270
Vascular smooth muscle contraction
lav04350
TGF-beta signaling pathway
lav04360
Axon guidance
lav04510
Focal adhesion
lav04520
Adherens junction
lav04530
Tight junction
lav04611
Platelet activation
lav04670
Leukocyte transendothelial migration
lav04810
Regulation of actin cytoskeleton
lav04921
Oxytocin signaling pathway
lav05135
Yersinia infection
lav05163
Human cytomegalovirus infection
lav05200
Pathways in cancer
lav05205
Proteoglycans in cancer
lav05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
100657418 (ROCK1)
04071 Sphingolipid signaling pathway
100657418 (ROCK1)
04024 cAMP signaling pathway
100657418 (ROCK1)
04022 cGMP-PKG signaling pathway
100657418 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100657418 (ROCK1)
04520 Adherens junction
100657418 (ROCK1)
04530 Tight junction
100657418 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100657418 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100657418 (ROCK1)
04670 Leukocyte transendothelial migration
100657418 (ROCK1)
04062 Chemokine signaling pathway
100657418 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
100657418 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100657418 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
100657418 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100657418 (ROCK1)
05206 MicroRNAs in cancer
100657418 (ROCK1)
05205 Proteoglycans in cancer
100657418 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
100657418 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
100657418 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100657418 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
lav03036
]
100657418 (ROCK1)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
100657418 (ROCK1)
Protein kinases [BR:
lav01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
100657418 (ROCK1)
Chromosome and associated proteins [BR:
lav03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
100657418 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
PH_9
Motif
Other DBs
NCBI-GeneID:
100657418
NCBI-ProteinID:
XP_010585127
UniProt:
G3TF10
LinkDB
All DBs
Position
Unknown
AA seq
1354 aa
AA seq
DB search
MSSGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSSRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRTSSNV
DKNLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGSQRRNLEST
VSQMEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
AQLQKQLEEANDLLRTESDTAARLRKSHTEMSKSISQLESLNIELQERNRILENSKTQTD
KDYYQLQAVLDAERRDRGHDSEMIGDLQARITSSQEEVKHLKHNLERLEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEEEVKNLTLQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIQEKNRENLKKIQELQNEKETLATQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEEMNSMLTRDIELLRKENE
ELTENMRKTEEEYKLKKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHKNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQEKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKEVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtctggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgcattaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgcatgaaagctgaagactatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaagacataaatccagcaggaag
gtatatgctatgaagcttcttagcaaatttgagatgatcaagagatctgattcagctttt
ttctgggaagaaagagacatcatggcttttgctaacagcccttgggttgttcagcttttc
tatgcattccaagatgatcgttatctctacatggtgatggaatacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcgcggttttatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttattcatagagatgtgaag
cctgataatatgctgctggataagtctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggcatggtacgatgtgacacagcagttggaacacctgattat
atttcccctgaagtattaaaatcccaaggcggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctttggttgggacttacagtaagattatgaaccataaaaattcacttaccttccct
gatgataatgacatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaagtgagattagggcgaaatggtgtagaagaaatcaaacgacatctcttcttcaaaaat
gatcaatgggcttgggaaacacttcgagacactgtagcaccagttgtacctgatttaagt
agtgacattgatacaagtaattttgatgacttggaagaagacaagggagatgaagaaaca
ttccctattcctaaagcttttgttggcaatcagctaccttttgtaggatttacgtattat
agcaatcgtaggtacttatcttcagcaaatcctaatgataacagaactagttccaatgtg
gataaaaatttgcaggaaagtttgcagaaaacaatctacaagttggaagaacaactacat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagaggggagccaaagaaggaatctagaatctaca
gtgtcacagatggagaaggagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagctgaacaggaaaatgagaagagaaggaatgtagaaaatgaagtttctacgttaaag
gatcagttggaagacttaaagaaagtcagtcagaattcacagcttgctaatgagaaattg
gcacaattacaaaagcagctagaagaagccaatgacttacttaggacagagtcagacaca
gctgcaagattaaggaagagtcacacagagatgagcaagtcgattagtcagctagagtcc
ctgaacatagaattgcaggagagaaatagaattttagagaattccaagacacaaacggac
aaggattattaccagctgcaagctgtattagacgctgaacgaagagacagaggccatgat
tctgagatgattggagaccttcaagctcgaattacatcttcacaagaggaggtgaagcat
ctcaaacacaatcttgaaaggctggaaggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataacttagagatagatttaaactacaagcttaaatcatta
caacaacggttagaacaagaagtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcaatctattgaagaggcaaagtctgttgcaatgtgtgagatggaaaaaaagctg
aaggaagaaagagaagcccgagagaaggctgaaaatagggttgttcagattgagaaacaa
tgttccatgctcgatgttgatctaaagcaatctcagcagaagctagagcatttgactgaa
aataaagaaagaatggaggaagaagttaagaatctaaccctacaactggagcaggaatca
aataagcgactgctattacaaaatgaattgaagacacaagcttttgaggcagacaattta
aaaggtttagagaagcagatgaaacaggaaataaatacattattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacaatatagaggaaacgaaggacagatgcgg
gagctacaagatcagcttgaagctgagcagtatttctcgacgctttataaaacccaggtg
aaggaacttaaggaagaaattcaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttgctactcaattggatctagcagaaacgaaagctgag
tctgagcagttagctcgagggcttttggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcttcaagaaacagacaagagattacagataaagatcacactgttagtcgg
ctagaagaaatgaacagcatgctaacgagagatattgaattactaagaaaagaaaatgaa
gagctaactgaaaacatgaggaagacagaggaagaatataaattgaagaaggaagaggag
atcagtaatcttaaggctgcctttgaaaagaatatcaatacagaacgaaccctcaaaaca
caggctgttaacaagttggcagaaataatgaatcgaaaagattttaaaattgatagaaag
aaagctaatactcaagatttaagaaagaaggaaaaggaaaatcgaaaactacaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtagtgaaacaccagaaggaactgaat
gacatgcaggcgcaattagtggaagaatgtacacataagaatgagcttcagatgcagttg
gctagcaaagagagtgatattgagcaactgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgccgatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttcagtaccaaacagagggaatattaagcgatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaaaattttgttctacaatgatgaacaagaaaaggaa
caatccaatccgtctatggtgttggacatagataaactgtttcatgttcgacctgtaacc
caaggggatgtgtatagagctgaaactgaagaaattcctaaaatattccagatattatat
gcaaacgaaggtgaatgtagaaaagaagtagagatggaaccagtacaacaagctgaaaaa
actaattttcaaaatcacaaaggccatgagttcattccgacactctaccacttcccagcc
aactgtgaggcctgtgccaaacctctctggcatgttttcaagccaccccctgccctagaa
tgtcgaagatgccatgttaagtgccacagagaccatttagataagaaagaggacttgatt
tctccctgtaaagtaagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaagaaatgggtaactcatttagtaaagaagatccccaaaaatcca
ccctccggttttgttcgcgcatcccctcgaaccctttctacaagatctactgcaaaccag
tctttcaggaaagtggtcaaaaatacatctggaaaaactagttaa
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integrated database retrieval system
