Loxodonta africana (African savanna elephant): 100657620
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Entry
100657620 CDS
T04351
Symbol
SETX
Name
(RefSeq) LOW QUALITY PROTEIN: probable helicase senataxin
KO
K10706
ATP-dependent RNA/DNA helicase, senataxin [EC:
5.6.2.5
5.6.2.3
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav05014
Amyotrophic lateral sclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
100657620 (SETX)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03021 Transcription machinery [BR:
lav03021
]
100657620 (SETX)
Enzymes [BR:
lav01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.3 DNA 5'-3' helicase
100657620 (SETX)
5.6.2.5 RNA 5'-3' helicase
100657620 (SETX)
Transcription machinery [BR:
lav03021
]
Eukaryotic type
RNA polymerase II system
Other transcription-related factors
Transcription termination factor
100657620 (SETX)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
AAA_11
AAA_12
AAA_19
UvrD-helicase
AAA_30
AAA_22
ResIII
nSTAND3
NAT10_TcmA_helicase
AAA_16
UvrD_C_2
Motif
Other DBs
NCBI-GeneID:
100657620
NCBI-ProteinID:
XP_010585851
LinkDB
All DBs
Position
Unknown
AA seq
2690 aa
AA seq
DB search
MSTCCWCTPGGGSTVDFLQRYAARTHTSEFQTADEDLCYCLECVAEYHKARDELPFLHEV
LWELETLRLINHFXKSMKAEIEADDDDIIVDNNGETHLFDFTGQDFENKLRVPLLEILKY
PYLLLHERVNELCVEALCRMEQANCSFQVFDKHPGIYLFLVHPNEMVRRWAILTARNLGK
VDRDDYYDLQEVLTCLFKVIELGLLESPDIYTSSVLEKGKLILLPSHMYDTTNYKNYWLG
ICMLLTILEEQAMDSLLLGSDKQNDFMQSILHTMERQSDDDNVDPFWPALHCFMVILDRL
GSKVWGQLIDPIEAFQTIINNVSYNREIQNIRNSSVRTKLEPESYLDDMVTCSQIVYNYN
PEKTKKDSGWRSAICPDYCPNMYEEMETLASVLQSDIGQDMRVHNSTFLWFIPFVQSLMD
LKDLGVAYIVEVIHHLHSEVKDVLNQRDAVCDKVTEFFLLILVSVIELHRNRKCLHLLWV
SSQQWVEAVVKCAKLPTTAFARSSEKSSGNCAKGTAMISSLSLHSMPSNSVQLACVQLIR
SLLKEGYQLGLQNLCKQFRDKLNFFLRGNLSLGWQLTSQETHELQTCLKQIIRNIKVKVP
QCSTSVDLTLACKSPPASYSKEETEQIGKKFKKDTHYLENSSPTFSKEPMKADTYQVQEG
ILIKASKTVAEDNEQNYVKDSKLEDHLLAESCLKQTKRLFTERAQDQAKINTGKQKSVKE
NSAHIPRNSTLRNGPERGCDRGVIISTCMLTDSSIDALENVSTSNEDFTLKDDALSKTSK
PKTKAQKDEICAKLSHVIKKQCQKSTLANNAISLEENLIVSNIESSYPRKDTGDQNGDGF
IYNLSLDPVGILDDNKSGGQKFQNSLLLKKKQVKIEKLDIFSSHENSRQIQESHVDGKDL
ISFTDVTNTSVKRTPSFKDTVTVLESKNREMSKSTDQVSSYLPREQTSGISPKSETLTDS
QIDRDLHKLSLIAQASVIKFPSDSNKKKNSTQLQRKVKDDKRCFTANQNNESTLVKESCR
EQIIIISDSDDDDDDGDGDQRILGFEKHTKIDKICIKKEYPEQHASRVNSSVEKKLIKEE
GTMFEESESQIFEFESPNEVFSVWQDHKPDDSSVQEVAEKSYLTHIADITNNWGYDTDFV
PEEVIKEVAESVEEHAEPQSSSISVEKFCEMEVKSKRKRFEKAMAEDPLRPSSSVRNEDQ
FDVLNERDLTETGFEGTDIRTATPNSSIQKATAASLKKSSPKLRTYSKPIRKVPVSKTPK
KTHSDAKKGQSKSLNYISCRTTPAIVPPKKFRQCPEPTSTVEKLGLKKAPRKAFDLSQQS
LECLNQLRDYGKTVGVVDTRKKAKLISPQTLSVKNNKKLLTSQDLQLQRQMRSKSQRSRQ
GLVDRESTDTAKAGPRAPSNSDTFVPESDQSAHSYKGGTEVIANNNGKQLLKCNSSEPET
ITPKYVSQVPDNTRLLNQCDSIMLNGRIPTNKIIVASSEGPFPGRGDLTAHQSEVAALKE
GEPESNSDTEDDNLFLTQNDPEDMDMCSQMETATVIEVLYGKDTFQIDDSVSLPQLQSLS
NKKCKHKDCVETTKNQGDYCSKHSEAKATDEDVFRKPGLPLSASKPLRPSTTKIFSSSST
SRNANLSKSLENTSALPPALKNKSNRVQSIGKVPQPASVMPQKPMGDGKSLCSVLSPTPD
NSNRQGYKLPFGESKSFLASSPVNSLSSSQSISDTFVKEILKWKYEMFVNFDQCGPPASL
YRSLSRPVPVRFQDSGDYFSVFFPLMILNTFETVAQEWISSPNKETFCQLRVRKFPADYK
KYWEFVVYLEECELARQLHPKENDLVFLVPERLNEENNTEGNLMQDPHEYYCGYVYKFRR
TSVMRNGKSECCVSIQTQDNLPVNLNELVKCIVISSLVTTQRKLKAMSLLSGRNQLARAV
LNPNPMDFCTKDLLTTTSERIITYLRDFNEDQKKAIETAYAMVKHSPSVAKICLIHGPPG
TGKSKTIVGLLYRLLTENQRRGYSDENSNAKIKQNRVLVCAPSNAAVDELMKKIILEFKE
KCKDKKNPLGNCGDINLVRLGPEKSINNEVLKFSLDSQVNHRMKKDLPCHVQEMHKRKEF
LDHQLDELSRQRALCRGVREVQRRELDEKIAQVSKERQELASKIKEVQGRPQKTQSIIIL
ESHIICCTLSTSGGLLLESAFRGQGGVPFSCVIVDEAGQSCEVETLTPLIHRCNKLILVG
DPKQLPPTVISMKAQEYGYDQSMMARFCKLLEENVEHNVISRLPVLQLTIQYRMHPDICL
FPSNYVYNRNLKTNRVTETNRCSSDWPFQPYLVFDVGDGSERRDNDSYVNVQEIKLVMEI
IKLIKDKRRDVTFRNIGIITHYKAQKMMIQKDLDKEFDRKGPAEVDTVDAFQGRQKDCVI
VTCVRANASQGSIGFLASLQRLNVTITRAKYSLFILGHLRTLMENPHWNHLIQDAQKRGA
IIKTCDKNYRHDAMKILKLKPVLQRSLTHPPPVAPEVSQPQGDLRSNKLDSGLAKTSYSS
PLCHSPDDSKEATVTVTSKDPERPPVQDRLRDPRLLRRLGSEAIEKLLRNPQSLSPQHSG
AAAPTGEPDFPITYQDLGTTVQQSTAKVATPSNHRPHMQCGLPAASTDVSTSKRKCDQEG
GLSHRRETRAFSEGEQEMYSSMTYHAMRNSDWDRRRLEKEDSSSKKRKLL
NT seq
8073 nt
NT seq
+upstream
nt +downstream
nt
atgagcacatgttgttggtgtacgcctggtggtggttccaccgttgacttcctacagcgc
tatgcagccaggacccataccagtgaatttcaaacagctgatgaagacctctgctattgc
ttggagtgtgtggctgaataccataaagcaagagatgaattgccattcttgcatgaggtt
ttatgggaattagaaactttacgtctcataaatcattttngaaaatccatgaaagcagaa
attgaggcagatgatgatgatattatagtagacaacaatggagaaacacatttgttcgac
tttactggccaagactttgaaaataagcttcgagttcctcttcttgaaatactgaaatat
ccttacctacttctacatgagcgtgttaatgaattatgtgtcgaagcactttgtcgaatg
gaacaagccaattgctcctttcaggtttttgacaaacatccaggaatctatctgtttttg
gtccatcccaatgaaatggttcggcgttgggctattctgactgcaagaaacttgggaaaa
gtggacagagatgattattatgacttacaggaggttttaacttgcctttttaaagtcatt
gagttggggcttttagaaagtccagacatttatacatcttctgtcctggagaagggtaaa
ttgattcttctcccatcgcacatgtatgatactactaactacaaaaactactggctaggt
atttgcatgttgctgaccattcttgaagaacaagccatggattctctgctgttgggctca
gacaaacaaaatgattttatgcaatcaatacttcacaccatggaaaggcaatcagatgat
gataatgtggaccctttctggccagcattacactgtttcatggtcattctggatcgcctt
gggtctaaggtctggggtcaacttattgatcctattgaagcatttcagaccattatcaac
aatgtgagctacaacagagaaatccagaatatacggaacagctctgtaaggaccaagtta
gaaccagagtcatacttggacgatatggtgacttgcagccagattgtatacaattataat
cctgaaaagacaaaaaaggattcagggtggcggtcggccatttgcccagattattgtcct
aacatgtatgaagaaatggaaacattagccagtgtgcttcagtcagatattggtcaagac
atgcgtgttcataacagcacatttctatggtttatcccttttgttcaatccctcatggat
cttaaggatttgggtgtggcttatatagtagaggttattcatcatctgcactctgaagtc
aaagatgttctcaaccaaagagatgctgtgtgtgacaaagtcactgaattttttcttcta
attttggtgtcagtgattgaactgcacagaaatagaaaatgtttgcatttgctgtgggtt
agttcacagcagtgggtggaagctgttgtaaaatgtgccaagctgcctaccactgcattt
gcacggagttctgagaagtcatcgggaaattgtgccaaaggaaccgcaatgatatcatct
ttgtcgttgcattccatgccatctaactctgtacaacttgcttgtgtacagctgattaga
agtctccttaaagagggttatcagcttgggctacagaatctttgtaagcaattccgggat
aagctcaactttttcctgcgaggaaatttatctctcggttggcagctgactagtcaggaa
acccatgagttacaaacttgtctaaagcaaattattagaaacataaaagtcaaagtacct
cagtgtagcacttctgtggatctgactcttgcatgtaaaagtcctcctgcatcttacagt
aaagaagaaactgaacaaatagggaagaagtttaaaaaagatacacattatctggaaaat
tctagtccaacattttctaaagaaccaatgaaagctgacacatatcaagtacaagagggt
atattgataaaagcaagtaaaactgtggcagaggacaatgagcaaaattatgtaaaggat
tccaaactagaagaccatctcttggctgaatcatgcttaaaacagactaaaagacttttt
actgaaagagctcaagatcaagctaaaataaatacggggaagcagaagtctgtaaaagag
aattctgcacatataccacggaatagtactttaagaaatggtccagaaaggggatgtgac
agaggagtgataatatcaacatgtatgttgactgattctagcattgatgccctggaaaat
gtgtccacatcaaatgaggattttactttaaaggatgatgctcttagtaaaacctcaaaa
cccaaaactaaggcacagaaagatgagatctgtgctaagttatcacatgtaataaagaag
caatgccagaaaagtactttggccaataatgcaatcagtttagaagaaaacctgattgta
tctaacattgagagttcctatccaaggaaagataccggagatcagaacggggatggcttc
atatacaatctgtctttagaccctgttggtattctggatgataataaaagtggaggacaa
aaatttcaaaatagtttattgctaaaaaagaaacaggtaaagattgagaaattagatatt
ttctcttcccatgaaaacagtcgtcagatacaggaaagccatgttgatggtaaagacttg
atctcatttacagatgtgaccaatacttcagtgaagagaacaccttcctttaaagatact
gtgactgtactcgaatcaaagaatagggagatgagtaagagtactgatcaggtttcttct
tacttgccaagagaacagacctctggcatcagtcctaaatctgaaaccttaacagattct
cagatagacagagacctccataaattgtctttaatagctcaagccagtgttattaagttt
ccatctgattcaaataaaaaaaagaactcaactcagctacaaagaaaagtaaaagatgat
aaaagatgtttcacagctaaccaaaataatgaatctactttggtcaaggaatcttgccgg
gaacagattattattatttcagattctgatgatgatgatgatgatggagatggagatcaa
agaattctgggttttgaaaaacacactaaaatagacaaaatatgcattaagaaagaatat
ccagagcagcatgcttcaagagttaatagtagtgtggaaaaaaagctaataaaagaggaa
ggaacaatgttcgaggaatctgagtctcagatttttgagtttgaaagtccaaatgaggta
ttttcagtttggcaggatcataaaccagatgacagttcagttcaagaggttgcagaaaaa
tcatatttgactcatatagctgatatcacaaataattggggttatgatacagattttgta
cctgaagaggttattaaagaagtagcagagagtgttgaagaacacgcagaaccacagagt
agtagtatttctgttgagaaattttgtgaaatggaagtaaaatccaagagaaaacgattt
gaaaaagctatggctgaagatcccctgaggccttcatcttctgtcagaaatgaggaccag
tttgatgttctgaatgagagagatcttactgaaactggttttgaaggtacagatataagg
actgcaactcccaattcaagcattcagaaagccactgcagcttcactaaagaagtcttct
ccaaagcttcgtacttactcaaaacccattaggaaagtcccagtttctaaaactcctaag
aaaacacattcagatgccaaaaaagggcaaagtaaaagtttgaattacataagttgtagg
acaactcctgctatagttccaccaaagaaatttcgccagtgtcctgaaccaacttcaaca
gtagaaaaacttggtttgaaaaaggccccacggaaggcatttgatttatctcagcagtct
ttagagtgtttgaatcaattacgtgattatggcaaaactgttggagtagttgatacccga
aaaaaggctaaattaatttctcctcaaactctctctgtcaagaataataagaaactgctg
acaagtcaagatcttcagttgcaaaggcaaatgagatccaaatcacaacgaagtagacaa
ggacttgttgatcgtgaaagtacagatactgcaaaggcagggccacgtgcaccatcaaat
tctgacacatttgtaccagaatctgatcagtcagctcatagttataaaggaggaactgag
gttattgctaacaataatggaaaacaattactaaaatgcaattcttcagaaccagaaacc
ataacaccaaaatatgtttctcaggtgcctgataatactcgtcttttgaaccagtgtgat
tctataatgttaaatgggagaataccaacaaataaaataattgtcgctagttcagagggc
ccttttccaggcagaggtgatctcacagcacatcagtctgaagtggcagctttgaaagag
ggagagcctgaatccaacagtgatacagaggatgataatttatttttaactcaaaatgat
cctgaagatatggatatgtgttcacaaatggagactgctacagtcattgaagtactttat
ggaaaagatacatttcagatagacgactctgtaagtctgcctcagttgcagtctttgagt
aacaaaaaatgtaagcacaaagattgtgttgaaaccacaaaaaaccagggtgattactgc
tcaaaacactctgaagctaaagcaacagatgaagatgtatttcgtaaacctggcttgcct
ctttctgcatctaaacctttaagaccttccactactaaaatttttagctcaagtagtact
tcacgaaatgctaatctttccaagtctttggaaaatacttcagcacttccaccagcacta
aaaaataaatcaaatagagtgcaatctattgggaaagtaccacagccagcctcggtgatg
cctcagaagccaatgggtgatggaaagagtttgtgcagcgttctttctccaactccggat
aattccaacaggcaaggctacaaacttccatttggtgaaagcaagtcttttttagcttcc
tctccagtaaacagtctctcgtcatcacagtccatctctgataccttcgttaaagagatc
ttaaaatggaaatatgaaatgtttgtgaactttgatcagtgtgggcccccagcaagtctt
tatcggtccctctcaagacctgtgcctgtcagatttcaagatagtggagattattttagt
gtcttttttcctttgatgatactgaatacttttgaaacagtggcacaggaatggatcagt
tctccaaataaagagactttctgtcagttgcgtgtacggaaatttcctgctgattataaa
aaatactgggaatttgtagtttatcttgaggaatgtgaactggctagacagcttcatcca
aaggaaaatgacttggtgtttttggttcctgaaagactaaacgaagagaataatacagaa
ggaaatctcatgcaagatccccatgaatattattgtggttatgtttataaatttcgccgt
acttcagtcatgcgtaacgggaaatctgagtgttgcgtttccatccagactcaagacaat
ttgccggtcaatttaaatgaacttgtgaaatgtattgtaatcagttctctggtaactaca
caaaggaagttgaaagccatgtctctgttgagtggtcggaaccaactggccagggctgtt
ctgaatccaaaccccatggacttctgtacaaaagatttactaactacaacttctgagaga
attattacctacttaagagatttcaatgaagaccaaaagaaagcaatagaaactgcatat
gcaatggtgaaacactcaccatcagttgcaaaaatctgtctgattcatggaccacctgga
acaggaaaatcaaaaactattgttggcctcctataccgcctactgacagagaaccagagg
agggggtattcagatgaaaactccaatgccaaaatcaaacagaaccgtgttcttgtgtgt
gcaccttccaatgcagctgttgatgaacttatgaaaaaaattatcctcgaattcaaggaa
aaatgtaaagacaagaagaatcctttgggaaactgtggagatataaatttagtacgactg
gggccggaaaagtctattaataatgaagttctaaaattcagtttggacagccaagttaac
cacagaatgaaaaaggacttaccttgtcatgttcaggagatgcataaaagaaaagagttt
ttagatcatcaactagatgagctttcccgccagcgtgctttgtgccgaggtgtaagggaa
gtacagaggcgagaattagatgaaaaaattgcccaagtttcaaaagaaaggcaggaactt
gcatctaagattaaagaggttcaaggacgcccacaaaaaacacagagtatcatcatatta
gagtcccatatcatctgctgcacattgagcacaagtggtggtttactgcttgagtctgct
tttcgtgggcaagggggtgtccccttcagttgtgtcattgttgatgaggctggacagtct
tgtgaagttgagacgcttactccactcatccatcgttgcaacaagctcatcctagtagga
gatcctaaacagctccctcccacagtcatttctatgaaggcacaggagtatggctacgac
cagtcgatgatggctcgcttctgtaagctgctggaggagaatgtagagcacaatgtgatc
agcagactgcccgttttacagctcactatccagtacaggatgcacccagacatatgcctc
ttcccttctaattatgtttataacagaaacttgaaaacaaacagagtgactgaaaccaat
cgatgttcatcagactggccatttcaaccttaccttgtgtttgatgtcggagatggttca
gaaagacgggataatgactcatatgttaatgttcaagaaataaagttggtgatggaaata
attaaacttattaaagacaaaagaagggatgttactttccgaaacattggcataataacc
cattacaaggctcagaagatgatgattcagaaggatttggacaaagagtttgatagaaaa
ggaccagcagaagtagatacggtggatgcattccagggtcgtcagaaggattgtgttatt
gttacatgtgtcagagcaaatgcctcgcaaggctcgattggattcctggcaagtttgcag
agattgaatgtcaccattacacgagccaagtacagcctcttcatcttgggacatttgagg
actctgatggaaaatccacattggaatcacctgattcaggatgctcagaagcgtggtgcc
attattaagacctgcgacaaaaactacaggcacgatgcaatgaagattctgaaactgaag
cctgtactgcagagaagtctgactcaccctcctcctgtagccccagaggtgtcccaaccc
cagggtgacttgcgcagcaacaaactagacagtggactcgccaagacatcttactcttct
cctctttgtcacagtcccgatgactccaaggaagctactgttactgttacttcaaaggac
cctgaaaggcctcctgttcaggaccgacttcgggacccaagactacttagaagactgggc
tctgaggccatagagaaactgctaagaaatccacagtctttgagcccccagcattctgga
gcagcagctcctacaggagagccagactttcctataacttaccaggatcttggtactact
gtgcagcagtccactgctaaagtagccactccgagcaaccacagacctcacatgcaatgt
ggacttccagctgctagtacggatgtttccacaagtaaaaggaaatgtgaccaggaagga
ggactcagccacagaagagagaccagggctttcagtgaaggggaacaggaaatgtatagc
tctatgacctatcacgcaatgaggaactctgactgggacaggaggagactggagaaggag
gacagtagttcaaagaaaagaaagcttttatag
DBGET
integrated database retrieval system
