Loxodonta africana (African savanna elephant): 100658099
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Entry
100658099 CDS
T04351
Symbol
FPGS
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00790
Folate biosynthesis
lav01100
Metabolic pathways
lav01240
Biosynthesis of cofactors
lav01523
Antifolate resistance
lav04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
100658099 (FPGS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100658099 (FPGS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100658099 (FPGS)
Enzymes [BR:
lav01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
100658099 (FPGS)
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Ortholog
Paralog
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
100658099
NCBI-ProteinID:
XP_003407759
UniProt:
G3SR80
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All DBs
Position
Unknown
AA seq
587 aa
AA seq
DB search
MSRVRARLHPALFLAAVSARWTTTGVGTERGLSARPAPQEPGMEYQDAVRTLNTLQTNAS
YLDQVKRQRGDPQTQLEAMVLYLAQSGLQVEDLDKLNIIHVTGTKGKGSTCAFTEQILRS
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWHLYHRLEKTKDGSCVSMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKGGIFKCGVPAYTVLQPDGPLAVLRDRAQQISCPLYLCPPLEALEEGGPPLTLGLEGE
HQRSNAALALQLARCWLQRQNHPGIGELKTSRSSLLRQLPLAPVFQPTSHMRHGLRDTEW
LGRTQVLRRGPLTWYLDGAHTASSVQACVRWFRQALQRRQRLNSGQEVRVLLFNATGDRD
RAALLKLLQPCQFDYAVFCPNLTEVSPTDNADQQNFTVTLDQMLLRCLEHQQHWGNLTEK
QASPDLWRPPNPEPSGPTSLLLAPHPPHSHSASSLIFSCISHALQWISQGRDPVFQPPCS
PRGLLTHPVAGSGASVLREAAAIHVLVTGSLHLVGGVLKLLEPSLSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgagggtacgggcccgcctgcacccggccctattcctggcggcggtttctgcgcgc
tggacgacgaccggggtcgggaccgagcgggggttaagcgcgcggccggcgccgcaagag
cctggcatggagtatcaggatgctgtgcgcacactcaacaccctgcagaccaatgctagt
tacctggaccaggtgaagcgccagcgaggcgacccccagacacaactggaagccatggtg
ctgtacctggcacagagtgggctgcaggtggaggacttggacaagctgaacatcatccat
gtcaccgggaccaaagggaagggttccacctgtgccttcactgaacagattctccgaagc
tacggcctgaagacaggattctttagctctccccacctggtgcaggtgcgtgagcggatc
cgcatcaatgggcagcccattagccctgagctgttcaccaagcacttctggcatctctac
caccggctggagaagaccaaggacggcagctgtgtctccatgcctgcctacttccgcttc
ctcacccttatggccttccacgtcttcctccaggagaaggtggacctggcggtggtggaa
gtgggcatcggtggggcttacgactgtaccaacatcatcaggaagcctgtggtatgtggg
gtctcctctcttggcatcgaccacaccagccttctgggggacacggtggagaagatcgca
tggcagaaagggggaatctttaagtgtggcgttcctgcctataccgtgctccagcctgat
ggtcccctggcggtgctgagggatcgtgcccagcagatctcatgtcctctctacctgtgc
ccaccactggaagccctggaggaagggggaccaccactgactctgggcctagagggggag
caccagcggtccaacgctgccttagccttacaactggcccgctgctggctgcagcggcag
aatcacccaggcatcggggagctgaagacatccagatccagcctcctgcggcagctgccc
ctggcacccgtgttccagcccacctcccacatgcggcacgggcttcgggacacagagtgg
ctgggcaggacccaggttctgcggcgcggacccctcacctggtacctggatggcgcgcac
acagccagcagcgtgcaggcctgcgtgcgctggttccgacaagcgctgcagaggcgccag
aggctgaacagcgggcaggaggtgcgggtcctgctcttcaatgccactggggaccgggac
cgggccgcactgctgaagctgctgcagccctgccagtttgactatgccgtcttctgcccc
aacctgacagaagtatcacccacagacaatgcagaccagcaaaacttcacagtgacattg
gaccaaatgctgcttcgctgccttgaacaccagcagcactggggcaacctgaccgagaag
caggccagcccagacctgtggaggcctcccaacccagagcctagtggacccacatccctg
ctactggcaccccacccaccccacagccacagcgccagctccctcatcttcagctgcatc
tcccatgctttacagtggatcagccaaggccgggaccctgtctttcagccaccctgttcc
ccacggggtcttctcacccaccctgtggcaggcagtggggccagtgtacttcgggaggct
gctgccatccatgtgctggtcacgggcagcctgcatctggtgggtggtgtcctgaagctg
ctggagccttccctgtcccagtag
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