Loxodonta africana (African savanna elephant): 100658490
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Entry
100658490 CDS
T04351
Symbol
PLA2G4A
Name
(RefSeq) cytosolic phospholipase A2 isoform X2
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00564
Glycerophospholipid metabolism
lav00565
Ether lipid metabolism
lav00590
Arachidonic acid metabolism
lav00591
Linoleic acid metabolism
lav00592
alpha-Linolenic acid metabolism
lav01100
Metabolic pathways
lav04010
MAPK signaling pathway
lav04014
Ras signaling pathway
lav04072
Phospholipase D signaling pathway
lav04217
Necroptosis
lav04270
Vascular smooth muscle contraction
lav04370
VEGF signaling pathway
lav04611
Platelet activation
lav04664
Fc epsilon RI signaling pathway
lav04666
Fc gamma R-mediated phagocytosis
lav04724
Glutamatergic synapse
lav04726
Serotonergic synapse
lav04730
Long-term depression
lav04750
Inflammatory mediator regulation of TRP channels
lav04912
GnRH signaling pathway
lav04913
Ovarian steroidogenesis
lav04921
Oxytocin signaling pathway
lav05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
100658490 (PLA2G4A)
00565 Ether lipid metabolism
100658490 (PLA2G4A)
00590 Arachidonic acid metabolism
100658490 (PLA2G4A)
00591 Linoleic acid metabolism
100658490 (PLA2G4A)
00592 alpha-Linolenic acid metabolism
100658490 (PLA2G4A)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100658490 (PLA2G4A)
04014 Ras signaling pathway
100658490 (PLA2G4A)
04370 VEGF signaling pathway
100658490 (PLA2G4A)
04072 Phospholipase D signaling pathway
100658490 (PLA2G4A)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100658490 (PLA2G4A)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100658490 (PLA2G4A)
04664 Fc epsilon RI signaling pathway
100658490 (PLA2G4A)
04666 Fc gamma R-mediated phagocytosis
100658490 (PLA2G4A)
09152 Endocrine system
04912 GnRH signaling pathway
100658490 (PLA2G4A)
04913 Ovarian steroidogenesis
100658490 (PLA2G4A)
04921 Oxytocin signaling pathway
100658490 (PLA2G4A)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100658490 (PLA2G4A)
09156 Nervous system
04724 Glutamatergic synapse
100658490 (PLA2G4A)
04726 Serotonergic synapse
100658490 (PLA2G4A)
04730 Long-term depression
100658490 (PLA2G4A)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100658490 (PLA2G4A)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
100658490 (PLA2G4A)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
100658490 (PLA2G4A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLA2_B
C2
cPLA2_C2
Motif
Other DBs
NCBI-GeneID:
100658490
NCBI-ProteinID:
XP_010589241
LinkDB
All DBs
Position
Unknown
AA seq
749 aa
AA seq
DB search
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGAFGDMLDTPDPYVELFICTTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPISSMKVGEKKEV
PFIFNQVTEMILEMSLEVCSAPDLRFSMALCDQEKTFRQQRKEKIKENMKKLLGPENSEG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSD
PDFPEKGPEEINEELMKNVSHNPLLLLTPQKIKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIHNRMNTTLSSLKEKVNTAQCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSASQSKGSTMEEE
LENITAKHIVSNDSSDSDDESQEPKGTENEDAERDYQNDNQASWVHRMLMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPLRGFTTQESLDEDELDAAVADPDEFERIYEPLDV
KSKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMN
KLPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKSPGVPRETK
EEKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKKAIIESIEYRR
QNPSRCSVSLSNVEARRFFNKEFLSKTTA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgtcatttatagatccttatcagcacattatagtggagcaccagtattcccacaagttc
actgtcgtggtgttacgtgccaccaaagtgacaaagggggccttcggtgacatgcttgat
actccagatccgtatgtggaacttttcatctgtaccactcctgacagcaggaaaagaaca
agacacttcaataatgacataaatcccgtgtggaatgagacctttgaatttattttggat
cctaatcaggaaaatgttttggagatcacattaatggatgccaattatgttatggatgaa
actctagggacagcaacatttcctatatcttctatgaaagtgggagagaagaaggaagtt
ccctttattttcaaccaagtcactgaaatgattctggaaatgtctcttgaagtttgctca
gccccagaccttcgatttagcatggctctctgtgatcaggagaaaactttcagacaacaa
agaaaagaaaaaataaaggagaacatgaagaaactcttgggtccagagaatagtgaaggc
ttgtattctacccgtgatgtgcctgtggtggccatattgggctcaggtgggggcttccga
gccatggtgggcttctccggtgtgatgaaggcactgtatgaatcagggattttggattgc
gccacctacattgctggtctttctggctccacatggtacatgtcaaccttatattctgat
cctgattttccagagaaagggccagaggagattaatgaagagttaatgaaaaatgttagc
cacaatccccttttacttctcacaccacagaagattaaacgatatgttgagtctttatgg
aagaagaaaagctctgggcaacctgtcacctttactgatatctttggaatgttaatagga
gaaacactaattcacaatagaatgaacactacgttaagtagtttgaaggaaaaagtcaac
actgcacaatgccctttacctcttttcacctgtctccatgtcaaacccgatgtttcggag
ttgatgtttgcagattgggttgaatttagtccatatgagattggcatggctaaatatggt
acttttatggcccctgacttatttggaagcaaattttttatgggaacagttgtgaagaaa
tatgaagaaaatcccttgcattttttaatgggtgtctggggaagtgctttttctatatta
ttcaacagagtcttgggtgtttctgcttcacaaagtaaaggttccacaatggaggaagaa
ttagaaaatattacagcgaaacatattgtgagtaatgatagctcggatagtgatgatgaa
tcacaagagcccaaaggcactgaaaatgaagatgccgaaagggactatcaaaatgataat
caagcaagttgggttcatcgaatgttaatggccttggtgagtgattcagctttattcaat
acccgagaaggacgtgctgggaaggtgcacaacttcatgttgggcttgaatctcaataca
tcctatccactgtctcctttgagaggctttaccacacaggagtccttggatgaagatgaa
ttggatgcagctgtggcagatcctgatgaatttgaaagaatatatgagcccctggatgtc
aaaagtaaaaagatccatgtagtggacagtgggctcacatttaacctgccctatcctttg
atcctgagaccacagagaggggtagatctcatcatttcctttgacttttctgcaagacca
agtgactccagtcctcccttcaaggaacttctacttgcagaaaagtgggctaaaatgaac
aagctcccttttccaaagattgatccttatgtgtttgatcgggaaggactgaaggagtgc
tatgtctttaaacccaagaaccctgatgtggagaaagattgcccaactatcattcacttt
gttctggccaacatcaacttcagaaagtacaagtctccaggtgttccaagagaaactaag
gaagagaaagaaatagctgactttgacatttttgatgatccagaatcaccattttcaacc
ttcaactttcaatatccaaatcaagcattcaaaaggctgcatgatctaatgcacttcaat
accctgaacaacattgatgtgataaagaaagccataattgaaagcatcgaatatagaaga
cagaatccatctcgttgctctgtttctctcagtaatgttgaggcaagacgattcttcaac
aaagagtttctaagcaaaaccacagcatag
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