Loxodonta africana (African savanna elephant): 100659553
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Entry
100659553 CDS
T04351
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00010
Glycolysis / Gluconeogenesis
lav00620
Pyruvate metabolism
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01230
Biosynthesis of amino acids
lav04910
Insulin signaling pathway
lav04930
Type II diabetes mellitus
lav04932
Non-alcoholic fatty liver disease
lav04950
Maturity onset diabetes of the young
Module
lav_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
lav_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
100659553 (PKLR)
00620 Pyruvate metabolism
100659553 (PKLR)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
100659553 (PKLR)
04950 Maturity onset diabetes of the young
100659553 (PKLR)
04932 Non-alcoholic fatty liver disease
100659553 (PKLR)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lav04147
]
100659553 (PKLR)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
100659553 (PKLR)
Exosome [BR:
lav04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
100659553 (PKLR)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
HpcH_HpaI
Motif
Other DBs
NCBI-GeneID:
100659553
NCBI-ProteinID:
XP_003415178
LinkDB
All DBs
Position
Unknown
AA seq
574 aa
AA seq
DB search
MSVQENLPPQQLWSWISKSQRDLATSILIGAPGGPAGYLRRASVAQLNQELGTAFFQQQQ
LSAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFS
HGSHEYHAESIANVREAVESFATSPLSYRPVAIALDTKGPEIRTGILRGGPESEVELAKG
SQVLVTVDPAFRTQGNADTVWVDYPNIARVVPVGGRIYIDDGLISLLVKKIGPEGLVTEV
ENGGVLGNRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIIFASFVRKASDVVAVRAA
LGPEGQGIKVISKIENHEGVKKFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRC
NLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGSFPVEAVKM
QHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRS
AQLLSRYRPRAAVIAVTRSAQAARQAHLCRGVFPLLYREPPEAIWADDVDRRVQFGIQSG
KLRGFIRVGDLVIVVTGWRPGSGYTNIMRVLSIS
NT seq
1725 nt
NT seq
+upstream
nt +downstream
nt
atgtcagtccaggagaacttaccaccccaacagctttggtcatggatctctaagtcccaa
agggacttggcaacgtccatcttgattggggctccaggagggccagctgggtacctgcgg
agggccagtgtggcccaactgaaccaggagctgggcactgccttcttccagcagcagcag
ctgtcggctgctatggcggacacattcctggagcacctctgcctgctggacatagactcg
gagcctgtggccgctcgcagtaccagcatcattgccaccatcgggccagcctctcgctcc
gtggagcgcctaaaggaaatgatcaaggctgggatgaacatagcgcgactcaacttctcc
cacggttcccacgagtatcacgctgagtccatcgctaacgtccgggaggcagtggagagc
tttgcaacttccccgctcagctatcggccggtggccatcgctctggacaccaagggaccg
gagatacgcactggaatcctccgggggggcccagagtcggaggtggagctagcgaagggc
tcccaggtgctggtgaccgtggacccagcatttcggacgcaggggaacgcggacaccgtg
tgggtggactaccccaatatcgcccgggtcgtgccggtcgggggccgcatctacattgac
gacgggctcatctccctcctggtcaagaaaattggcccagaggggctggtgacggaagtg
gagaacggcggcgtcctgggcaaccgaaaaggggtgaacttgccgggcgcccaggtggac
ctgcctgggctgtccgagcaagatgtccgggacctgcgctttggggtggagcatggcgtg
gacatcatcttcgcctcctttgtgcggaaggccagcgacgtggtggccgtccgggctgct
ctggggccggaagggcagggcatcaaggtcatcagcaaaatcgagaaccacgaaggcgtg
aaaaagtttgatgaaatcctggaggtgagcgatggcatcatggtggcccggggtgacctg
gggatcgagattccagctgagaaggttttcctggctcagaagatgatgatcgggcgctgt
aacttggccggcaagcccgtagtctgtgccacacagatgctggagagcatgatcactaag
ccccggccaacgcgggcagagacgagtgacgtggccaacgctgtgctggacggggcagac
tgcatcatgctgtcgggggagactgccaagggcagctttcctgtggaggctgtaaagatg
cagcacgcgattgcccgtgaggcagaggctgcggtctaccaccggcagctgttcgaggag
ctgcgtcgggcagcaccactgagccgtgaccccactgaggtcaccgccataggtgctgtg
gaggctgccttcaagtgctgtgcggctgccatcatcgtgctgaccacgactggccgttca
gcccagcttctttctcgatatcgacctcgagcagcagtcattgctgtcactcgttctgcc
caggctgcccgccaggcccacctatgccgaggagtctttcccttgctctatcgtgaacct
ccagaggccatctgggcagacgatgtggatcgccgggtccaatttggcattcaaagtgga
aagctccgtggcttcatccgtgttggggacctggtgattgtggtgacaggctggcggcct
ggctccggctataccaacatcatgcgggtgctgagcatatcctga
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