Loxodonta africana (African savanna elephant): 100659617
Help
Entry
100659617 CDS
T04351
Symbol
HIF1A
Name
(RefSeq) hypoxia-inducible factor 1-alpha
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04066
HIF-1 signaling pathway
lav04137
Mitophagy - animal
lav04140
Autophagy - animal
lav04148
Efferocytosis
lav04659
Th17 cell differentiation
lav04919
Thyroid hormone signaling pathway
lav05167
Kaposi sarcoma-associated herpesvirus infection
lav05200
Pathways in cancer
lav05205
Proteoglycans in cancer
lav05208
Chemical carcinogenesis - reactive oxygen species
lav05211
Renal cell carcinoma
lav05230
Central carbon metabolism in cancer
lav05231
Choline metabolism in cancer
lav05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
100659617 (HIF1A)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
100659617 (HIF1A)
04137 Mitophagy - animal
100659617 (HIF1A)
04148 Efferocytosis
100659617 (HIF1A)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
100659617 (HIF1A)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100659617 (HIF1A)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100659617 (HIF1A)
05205 Proteoglycans in cancer
100659617 (HIF1A)
05208 Chemical carcinogenesis - reactive oxygen species
100659617 (HIF1A)
05230 Central carbon metabolism in cancer
100659617 (HIF1A)
05231 Choline metabolism in cancer
100659617 (HIF1A)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
100659617 (HIF1A)
09162 Cancer: specific types
05211 Renal cell carcinoma
100659617 (HIF1A)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
100659617 (HIF1A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
lav03000
]
100659617 (HIF1A)
Transcription factors [BR:
lav03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
100659617 (HIF1A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
DDRGK
Motif
Other DBs
NCBI-GeneID:
100659617
NCBI-ProteinID:
XP_010586982
LinkDB
All DBs
Position
Unknown
AA seq
822 aa
AA seq
DB search
MEGAGGANDKKKISSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGDLDIEDEMKAQMNCFYLKALDGFVMVLTDDGDMIYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVKKGKEQNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQSQCGYKKPPMTCLVLICEPIPHPSNIEVRIDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYDYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTECV
LKPVESSDMKMTQLFTKVESEDTSSLFDKLKKEPDALTLLAPAAGDTIISLDFGSNDTES
DDQQLEEVPLYNDVMLPSSSEKLQNMNLAMSPLPASETPKPLRSSADPALNQEVALKLEP
NPESLELSFTMPQIQDQPASPSDGSTRQSSPEPNSPSDYCFDVDSDMVNEFKLELVEKLF
AEDTEAKNPFATQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESSSASPQSTSTITVFQ
QTQMQEPAIIANTSTATTDELKTVTKDGMEDIKILIASPSPTHVPKETTSARTSPYNDTQ
SRTASPSRAGKGVIEQTEKSHPRSPNLLSVTLSQRTTVPEEELHPKIIALQNAQRKRKME
HDGSLSQAVGIGTLLQQPEDRATTSLSWKRVKGCKSSEQNGLEQKTIILIPSDLACRLLG
QSMDESGLPQLTSYDCEVNAPVQGSRNLLQGEELLRALDQVN
NT seq
2469 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgcgaacgacaagaaaaagattagttctgaacgccgaaaagaa
aagtctcgagatgcagccaggtctcggcgaagtaaagagtctgaagttttttatgagctt
gctcatcagttgcctcttccccataatgtcagctcgcatcttgataaagcttctgttatg
aggcttaccattagctacttgcgtgtgaggaaacttctagatgctggtgatttggatatt
gaagatgaaatgaaggcacagatgaattgcttttatctgaaagctctagatggttttgtt
atggttctcacagatgatggtgacatgatttacatttctgataacgtgaacaaatacatg
ggattaactcagtttgaattaactggacacagtgtgtttgattttactcatccgtgtgac
catgaggaaatgagagaaatgcttacccacagaaatggccctgtgaaaaagggtaaagag
caaaacacacaacgaagcttttttctcagaatgaagtgtaccctaactagccgggggaga
actatgaacataaagtctgcaacatggaaggtacttcattgcacaggccatattcatgta
tacgacaccaacagtaaccaatctcagtgtgggtataagaaaccacctatgacatgtttg
gtgctgatatgtgaacccattcctcacccatcaaatattgaagttcgaatcgatagcaag
acttttctcagtcgtcacagcctggacatgaaattttcttattgtgatgaaagaattact
gaattgatgggatatgagccagaagaacttttgggtcgctcaatttatgactattatcac
gctttggactctgatcatctgaccaaaactcatcacgatatgtttactaaaggacaggtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatacaacactaagaactctcaaccacaatgcattgtatgtgtaaattat
gttgtgagtggtataattcagcacgacttgattttctcccttcaacaaacagaatgtgtc
ctcaaacctgttgagtcttcagatatgaaaatgactcagctattcaccaaagttgaatca
gaagatacaagtagtctctttgataaacttaagaaggaacctgatgctttaactttgctg
gccccagcggctggagacacaatcatatctttagattttggcagcaatgacacagaaagt
gatgatcaacaacttgaggaagttcccttgtataatgatgtaatgcttccctcatccagt
gaaaaattacagaatatgaatttggcaatgtctccattacctgcctctgaaactccaaag
ccacttcgaagtagtgctgaccctgcactaaatcaagaagttgcattaaaattagaacca
aatccagagtcactggaactttcttttactatgccccagattcaagatcagccagccagc
ccttctgatggaagcactagacaaagttcaccagagcctaacagtcccagtgactattgt
tttgatgtggacagtgatatggttaatgaattcaagttggaattggtagagaaacttttt
gctgaagacacagaagcaaagaatccatttgccacacaggacactgatttagacttggag
atgttagccccctacatcccaatggatgatgacttccagttacgttcatttgatcagtta
tcaccattagaaagcagttctgcaagccctcaaagtacgagcacaattacagtattccag
cagactcaaatgcaggaacctgctattatcgccaacacttccactgccaccactgatgaa
ttaaaaacagtgacaaaagacggtatggaagacattaaaatattgattgcatctccatct
cctacccacgtacctaaagaaactactagtgccagaacatcaccatataatgatacacaa
agtcggacagcctcaccaagcagagcaggaaaaggagtcatagaacagacagaaaaatct
catccaagaagccctaacctgttatctgtcactttgagtcaaaggactactgttcctgag
gaagaattacacccaaagataatagctttgcagaacgctcagagaaagcgaaagatggaa
cacgatggctcactttctcaagcagtaggaattggaacattattacaacagccagaggat
cgtgccactacatcactttcttggaaacgtgtaaaaggatgcaaatctagtgaacagaat
ggactggagcaaaagacaattattttaataccctctgatttagcatgtagactgctgggg
caatcaatggatgagagtggattaccacagctgaccagttacgattgtgaagttaatgct
cctgtacaaggcagcagaaacctactgcagggtgaagaattactcagagctttggatcaa
gttaactga
DBGET
integrated database retrieval system
