| Entry |
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| Symbol |
ATF4
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| Name |
(RefSeq) cyclic AMP-dependent transcription factor ATF-4 isoform X2
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| KO |
| K04374 | cyclic AMP-dependent transcription factor ATF-4 |
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| Organism |
lav Loxodonta africana (African savanna elephant)
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| Pathway |
| lav04141 | Protein processing in endoplasmic reticulum |
| lav04261 | Adrenergic signaling in cardiomyocytes |
| lav04925 | Aldosterone synthesis and secretion |
| lav04927 | Cortisol synthesis and secretion |
| lav04928 | Parathyroid hormone synthesis, secretion and action |
| lav04932 | Non-alcoholic fatty liver disease |
| lav04935 | Growth hormone synthesis, secretion and action |
| lav05022 | Pathways of neurodegeneration - multiple diseases |
| lav05163 | Human cytomegalovirus infection |
| lav05166 | Human T-cell leukemia virus 1 infection |
| lav05207 | Chemical carcinogenesis - receptor activation |
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| Brite |
KEGG Orthology (KO) [BR:lav00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
100662521 (ATF4)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100662521 (ATF4)
04668 TNF signaling pathway
100662521 (ATF4)
04022 cGMP-PKG signaling pathway
100662521 (ATF4)
04151 PI3K-Akt signaling pathway
100662521 (ATF4)
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
100662521 (ATF4)
09143 Cell growth and death
04210 Apoptosis
100662521 (ATF4)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100662521 (ATF4)
04922 Glucagon signaling pathway
100662521 (ATF4)
04912 GnRH signaling pathway
100662521 (ATF4)
04915 Estrogen signaling pathway
100662521 (ATF4)
04926 Relaxin signaling pathway
100662521 (ATF4)
04935 Growth hormone synthesis, secretion and action
100662521 (ATF4)
04918 Thyroid hormone synthesis
100662521 (ATF4)
04928 Parathyroid hormone synthesis, secretion and action
100662521 (ATF4)
04925 Aldosterone synthesis and secretion
100662521 (ATF4)
04927 Cortisol synthesis and secretion
100662521 (ATF4)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
100662521 (ATF4)
09156 Nervous system
04725 Cholinergic synapse
100662521 (ATF4)
04728 Dopaminergic synapse
100662521 (ATF4)
04720 Long-term potentiation
100662521 (ATF4)
04722 Neurotrophin signaling pathway
100662521 (ATF4)
09149 Aging
04211 Longevity regulating pathway
100662521 (ATF4)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100662521 (ATF4)
05203 Viral carcinogenesis
100662521 (ATF4)
09162 Cancer: specific types
05215 Prostate cancer
100662521 (ATF4)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
100662521 (ATF4)
05161 Hepatitis B
100662521 (ATF4)
05163 Human cytomegalovirus infection
100662521 (ATF4)
09164 Neurodegenerative disease
05010 Alzheimer disease
100662521 (ATF4)
05012 Parkinson disease
100662521 (ATF4)
05014 Amyotrophic lateral sclerosis
100662521 (ATF4)
05020 Prion disease
100662521 (ATF4)
05022 Pathways of neurodegeneration - multiple diseases
100662521 (ATF4)
09165 Substance dependence
05030 Cocaine addiction
100662521 (ATF4)
05031 Amphetamine addiction
100662521 (ATF4)
05034 Alcoholism
100662521 (ATF4)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100662521 (ATF4)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100662521 (ATF4)
04934 Cushing syndrome
100662521 (ATF4)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:lav03000]
100662521 (ATF4)
Transcription factors [BR:lav03000]
Eukaryotic type
Basic leucine zipper (bZIP)
AP-1(-like) components, CRE-BP/ATF
100662521 (ATF4)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Unknown
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| AA seq |
353 aa
MAEMSFLSSEVLVGDLMSPFDQSGLGVEETLGLLDDYLEVAKHCRPHGFSRDKAKAGSSE
WLAVDGLVDASDNGKEDAFSGTDWMVEKMDLKEFDFDALLSLDDLEIMPAELLATLDDTC
DLLDPLVQETNEPPQTLNPIGHLPESFPQTDQVAPLTFLQPLPHCPGVLASTPDHSFSLE
LGSEVDISEGDRKADSFLYVTAVPQCIKEEEAPSDNDSGICMSPESCPGSPQHSPSTSGG
SPDRSLLSPPALGGSARPKPYDPPREKVVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKR
AEQEALTDECKELEKKNEALKERADSLAKEIQYLKDLIEEVRRARGKKRDSLG |
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| NT seq |
1062 nt +upstreamnt +downstreamnt
atggccgagatgagcttcctgagcagcgaggtgttggtgggggacttgatgtcccccttc
gaccagtcgggtttgggggttgaagaaaccctaggtctcttagacgactacctggaggtg
gccaagcactgcagaccgcatgggttctccagggacaaggctaaggcgggctcctccgaa
tggctggctgtggacgggttggtcgatgcctcagacaacggcaaggaggatgccttctcc
ggaacagattggatggtggagaaaatggatctgaaggagtttgacttcgatgccctattg
agtctagacgacctggaaattatgccagccgagcttttggccacgttggatgacacctgt
gatctcttagaccctttagtccaggagacgaatgagcccccccagacattgaacccaatt
ggccatctcccagaaagttttccacaaactgaccaggttgccccattgaccttcctgcaa
cctctgccccattgccccggagtcctggcctccactccagaccattcttttagtttagag
ctcggcagtgaagtggatatttccgaaggagacagaaaggcagattcctttctgtatgtt
accgcggtccctcagtgcataaaagaggaggaggccccttcagataatgacagtggcatc
tgcatgagtcctgaatcctgtccaggatctccccagcacagcccctccacctctgggggc
tctccagataggagcttgctgtctccacctgctctcggtggctctgctcgccccaaacct
tatgatcctcctagagagaaggtggtagcagcaaaagtaaagggagagaaattggataag
aaactgaaaaaaatggagcagaacaagacagcagccactaggtaccgtcagaaaaagagg
gcagagcaggaggccctcacggatgagtgtaaggagctagaaaagaaaaacgaggctttg
aaggagagggcagattctctggccaaggagatccagtatctgaaagacttgatagaagag
gtccgcagggccagggggaagaaaagggattccctagggtag |
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