Loxodonta africana (African savanna elephant): 100664128
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Entry
100664128 CDS
T04351
Name
(RefSeq) fibroblast growth factor receptor 2 isoform X1
KO
K05093
fibroblast growth factor receptor 2 [EC:
2.7.10.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01521
EGFR tyrosine kinase inhibitor resistance
lav04010
MAPK signaling pathway
lav04014
Ras signaling pathway
lav04015
Rap1 signaling pathway
lav04020
Calcium signaling pathway
lav04144
Endocytosis
lav04151
PI3K-Akt signaling pathway
lav04550
Signaling pathways regulating pluripotency of stem cells
lav04810
Regulation of actin cytoskeleton
lav05200
Pathways in cancer
lav05215
Prostate cancer
lav05226
Gastric cancer
lav05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100664128
04014 Ras signaling pathway
100664128
04015 Rap1 signaling pathway
100664128
04020 Calcium signaling pathway
100664128
04151 PI3K-Akt signaling pathway
100664128
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
100664128
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
100664128
09142 Cell motility
04810 Regulation of actin cytoskeleton
100664128
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100664128
05230 Central carbon metabolism in cancer
100664128
09162 Cancer: specific types
05226 Gastric cancer
100664128
05215 Prostate cancer
100664128
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100664128
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100664128
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
lav04090
]
100664128
00536 Glycosaminoglycan binding proteins [BR:
lav00536
]
100664128
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
100664128
Protein kinases [BR:
lav01001
]
Receptor tyrosine kinases (RTK)
FGFR family [OT]
100664128
CD molecules [BR:
lav04090
]
Proteins
100664128
Glycosaminoglycan binding proteins [BR:
lav00536
]
Heparan sulfate / Heparin
Growth factors/receptors
100664128
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
I-set
Ig_3
Pkinase
ig
Ig_2
V-set
Ig_5
ABC1
Ig_4
C2-set_2
V-set_CD47
CBM9_1
Motif
Other DBs
NCBI-GeneID:
100664128
NCBI-ProteinID:
XP_023396656
LinkDB
All DBs
Position
Unknown
AA seq
750 aa
AA seq
DB search
MGLTSTWRYGRGLGIGTVTMVSWARFICLVVVTMATLSLARPSFSLVEDTTLEPEEPPTK
YQISQPEVYVATPGESLELGCLLKDAAMISWTKDGVHLGPNNRTVLIGEYLQIKGATPRD
SGLYACTAARSVDSETLYFMVNVTDAISSGDDEDDTDGSEDFVSENSNNKRAPYWTNTEK
MEKRLHAVPAANTVKFRCPAGGNPTPTMRWLKNGKEFKQEHRIGGYKVRNQHWSLIMESV
VPSDKGNYTCVVENEYGSINHTYHLDVVERSPHRPILQAGLPANASTVVGGDVEFVCKVY
SDAQPHIQWIKHVEKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVTFEDAGEYT
CLAGNSIGISFHSAWLTVLPAPVREKDITASPDYLEIAIYCIGVFLIACMVVTVILCRMK
TTTKKPDFSSQPAVHKLTKRIPLRRQVTVSAESSSSMNSNTPLVRITTRLSSTADTPMLA
GVSEYELPEDPKWEFPRDKLTLGKPLGEGCFGQVVMAEAVGIDKEKPKEAVTVAVKMLKD
DATEKDLSDLVSEMEMMKMIGKHKNIINLLGACTQDGPLFVIVEYASKGNLREYLRARRP
PGMEYSYDINRVPEEQMTFKDLVSCTYQLARGMEYLASQKCIHRDLAARNVLVTENNVMK
IADFGLARDINNIDYYKKTTNVSLWWECGEGAGRAFRIKDCRFSELEGTDKAAWLRPLFL
FFCLLFVTFSTSSLSLYFVITCHRVGAYSW
NT seq
2253 nt
NT seq
+upstream
nt +downstream
nt
atgggattaacgtccacatggagatatggaagaggactgggcattggcaccgtaaccatg
gtcagctgggctcgcttcatctgcctggtcgtggtcaccatggcaaccttgtccctggcc
cggccctcattcagtttagtcgaggataccacattagagccagaagagccgccaaccaaa
taccaaatctctcaaccagaagtgtacgtggccacgccaggggagtcgctagagttgggc
tgcctgttgaaagatgccgccatgatcagttggactaaggatggggtacatttggggccc
aacaataggacagtgcttattggggagtacttgcagataaaaggcgccacgcctagagac
tccggcctgtatgcttgtactgctgctaggagtgtagacagtgagaccttgtacttcatg
gtcaatgtcacagatgcaatctcatctggggatgatgaggacgacacagatggctccgag
gactttgtcagtgagaacagtaacaacaagagagcaccatactggaccaacacggagaag
atggagaagcggctgcatgctgtccccgcggccaataccgtcaagttccgctgcccagct
ggggggaacccgacacccaccatgaggtggctgaagaacgggaaggaatttaagcaggag
catcgcattggtggctataaggtacgaaaccagcactggagccttattatggagagtgtg
gtcccatccgacaaaggaaattatacctgcgtggtggaaaatgaatacgggtccatcaat
cacacataccacctcgatgttgttgaacggtccccacaccggcccatcctccaagctgga
ctgccggcaaatgcctccaccgtggtcgggggtgacgtggaatttgtctgcaaagtgtac
agtgatgcccagccccacatccagtggatcaagcatgttgaaaagaacggcagcaaatac
gggcccgacgggctgccctaccttaaggttctcaaggctgccggtgttaacaccacggac
aaagagattgaggttctctatattcggaatgtaacttttgaggatgctggggaatatacg
tgcttggcgggtaattctattgggatatcctttcactctgcatggttgacagttctgcca
gctcctgtaagagaaaaggacattaccgcttccccagactacctggagatagccatttac
tgcataggggtcttcttaattgcctgtatggtggtgacagtcatcctgtgccgaatgaag
acaacgaccaagaagccagactttagcagccagccggctgtgcacaagctgaccaagcgc
atccctctgcggagacaggtaacagtttctgccgagtccagctcctccatgaactccaac
accccactggtgaggataacaacacgcctctcctcaacagcagacacgcccatgttggca
ggggtctctgagtacgaattgccagaggatccaaaatgggagtttccaagagataagctg
acgctgggcaaacccctgggggaaggttgctttgggcaagttgtcatggctgaagcagtg
ggaatcgacaaagagaagcccaaggaagcagtcactgtggctgtgaagatgttgaaagat
gatgccacagagaaagacctttccgatctggtgtcagagatggagatgatgaagatgatt
ggaaaacacaaaaacatcatcaatctcctgggagcctgtacgcaggatggcccactcttt
gtcatagtggagtacgcctcgaagggtaacctccgcgagtacctgcgtgcccgcaggccc
cctgggatggagtactcctacgacatcaaccgcgttcctgaggaacagatgaccttcaag
gacttggtgtcgtgcacataccagctggccagaggcatggagtacttggcttcccaaaaa
tgtattcatcgagacttagcagccagaaatgttttggtaacagaaaacaatgtgatgaaa
atagcagacttcggactggccagagacatcaacaatatagactactacaaaaagaccacg
aatgtaagtctatggtgggagtgtggtgagggggcgggcagagcgttccggataaaagat
tgtagattttcagagctggaaggtactgacaaggctgcatggctccgccctttattttta
ttcttttgcttactctttgtcaccttctcaacaagcagtcttagcctgtattttgtcatt
acttgccatcgagttggcgcctactcgtggtga
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