Loxodonta africana (African savanna elephant): 100664597
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Entry
100664597 CDS
T04351
Symbol
PDE2A
Name
(RefSeq) cGMP-dependent 3',5'-cyclic phosphodiesterase
KO
K18283
cGMP-dependent 3',5'-cyclic phosphodiesterase [EC:
3.1.4.17
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00230
Purine metabolism
lav01100
Metabolic pathways
lav04022
cGMP-PKG signaling pathway
lav04740
Olfactory transduction
lav04925
Aldosterone synthesis and secretion
lav05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
100664597 (PDE2A)
09130 Environmental Information Processing
09132 Signal transduction
04022 cGMP-PKG signaling pathway
100664597 (PDE2A)
09150 Organismal Systems
09152 Endocrine system
04925 Aldosterone synthesis and secretion
100664597 (PDE2A)
09157 Sensory system
04740 Olfactory transduction
100664597 (PDE2A)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
100664597 (PDE2A)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
100664597 (PDE2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
GAF
GAF_2
GAF_3
Motif
Other DBs
NCBI-GeneID:
100664597
NCBI-ProteinID:
XP_023394813
LinkDB
All DBs
Position
Unknown
AA seq
1190 aa
AA seq
DB search
MGQACGHSILCRSQQYPAARPAEPLVILAMERAQTALALIFVGDRHTQAQAMNLVGPVAG
TAEGGDPQGTGTCGTTRYPAAATLQVSTHLVQLLSPTVTEENHRFQQSRAGVQLVPGRNL
PSSVPAPLKPLPLAPPPSAPQIRELAGTPLHRRQHPQGVKTINWSVTEPMWNCVYVTVWG
DTVDPRSMGCDTEGEGHPGESDRGGITVCDPVVTPTHSLMPIQEPPELHPPPVFSGEHGK
EEVETSIQWTCEGQDQGAESSSRGKGTRAGLGFWEDRTRAGLGDRVATWRVGEEWAGETG
AGGNRECGRVRDGEREEMPSERKREDAEVGKDAEPHGDETREPLVTERWKLAVADALLSL
GSVIDIAGLQQAVKEALSAVLPRVETVYTYLLDGESRLVCEDPPHELLQEGKVREAVISQ
KRLGCNGLGPSDLPGKPLARLVAPLAPGTQVLVIPLVDKEAGAVAGVILVHCGQLSDSEE
WSLQLYDLDASSLQLKVLQYLQQETGASRCCLLLVSEDNLQLSCKVIGEKVLEEEISFPL
TMGRLGQVVEDKKSIQLKDLTSEDVQQLQNVLGCGLQAMLCVPVISRATDQVVALACAFN
KLGGDLFTEQDEHVIQHCFHYTSTVLTSTLAFQKEQKLKCECQALLQVAKNLFTHLDDVS
VLLQEIITEARNLSNAEICSVFLLDQNELVAKVFDGGVVDDESYEIRIPADQGIAGHVAT
TGQILNIPDAYAHPLFYRGVDDSTGFRTRNILCFPIKNENQEVIGVAELVNKINGPWFSK
FDEDLATAFSIYCGISIAHSLLYKKVNEAQYRSHLANEMMMYHMKVSDDEYTKLLYNGIQ
PVAAIDSNFASFTYTPRSLPEDDTSMAILSMLQDMNFINNYKIDCPTLARFCLMVKKGYR
DPPYHNWMHAFSVSHFCYLLYKNLELANYLEDIEIFALFISCMCHDLDHRGTNNSFQVAS
KSVLAALYSSEGSVMERHHFAQAIAILNTHGCNIFDHFSRKDYQRMLDLMRDIILATDLA
HHLRIFKDLQKMAEVGYDRTNKQHHSLLLCLLMTSCDLSDQTKGWKTTRKIAELIYKEFF
SQGDLEKAMGNRPMEMMDREKAYIPELQISFMEHIAMPIYKLLQDLFPKAAELYERVASN
REHWTKVSHKFTIRGLPSNNSLDFLDEEYEVPKMDGAGGPVNGCCSLDAE
NT seq
3573 nt
NT seq
+upstream
nt +downstream
nt
atggggcaggcgtgcggccactccatcctctgcaggagccagcagtacccggcagcgcga
ccggctgagccgcttgtcatcctggccatggagagggctcagacagcccttgccctcatc
tttgttggagacaggcacacccaggcccaggcaatgaacctggtggggccagttgcaggc
acggctgagggaggagatccccagggcacaggaacatgtggcacaaccagataccctgcc
gcagccaccctacaagtgtccacacacctggtgcagctcctgtcacctaccgtcactgag
gagaaccacagattccagcagtcacgggcaggcgtccagctcgtgccaggccgcaacctc
ccttcatccgttcctgcccccctaaaacccctcccactggctcctcccccctcagctcct
caaatccgagaactggctgggacccccttgcacaggagacagcacccccagggagtaaag
acaatcaactggagtgtgacagagccaatgtggaactgtgtgtatgtcaccgtgtggggt
gacactgtggacccccggagcatggggtgtgacaccgagggtgagggccatcctggtgag
agtgaccggggtggtatcactgtgtgtgaccctgtggtgacccccacccactccctcatg
cccattcaggagccaccagagctacacccacccccagtcttcagtggggaacacgggaag
gaggaggtggagacgagcatccagtggacatgcgaagggcaagaccagggagcagaatcc
agcagccggggcaagggcacgagagcaggcctgggcttctgggaggaccggaccagggct
gggttgggggacagggtggctacttggagggttggggaggagtgggcaggagagacagga
gcgggtgggaacagggagtgtgggagagtgagagatggcgagcgggaggagatgccatct
gagaggaagagagaggatgcggaggtgggaaaagatgcagagcctcatggagatgagaca
cgggagccgcttgtgacagagagatggaagctggctgtggcagatgctttgctgagctta
ggctctgtcatcgacattgcgggccttcaacaggctgtcaaggaggccctgtcagctgtg
ctccccagagtggagacggtctacacctacctgctggatggggagtccaggctggtgtgt
gaggaccctccgcatgagctgctccaggaggggaaagtccgagaggctgtgatctcccag
aaacggctgggctgcaatggactgggcccttcagacctgccagggaagcccttggccaga
ctggtggctccactggcccctggcacccaagtgctggtcataccgctggtggacaaggag
gccggggctgtggctggtgtcatcttggtgcactgtggccagctaagtgacagtgaggag
tggagcctgcagctctacgacctggacgcctcttccctgcagctgaaagttctccaatac
ctgcagcaggagaccggggcatcccggtgctgcctcctgctggtgtccgaggacaacctt
cagctttcctgcaaggtcattggagaaaaagtgctggaggaagagatcagctttccactg
acaatgggtcgcctgggccaggtggtggaagacaagaagtccatccagctgaaggacctc
acctctgaggatgtgcaacagctgcaaaacgtgctgggctgtgggctgcaggccatgctc
tgtgtccctgtcatcagccgggccactgaccaggtggtggccttggcctgcgccttcaac
aagcttggaggagacttgttcacagaacaggatgagcacgtgatacagcactgtttccac
tacacaagcaccgtgctcaccagcaccttggccttccagaaggagcagaaactcaagtgt
gagtgccaggctcttctccaagtggcaaagaacctcttcactcacctggatgacgtctct
gtcctgctccaggagatcatcaccgaggccagaaacctcagcaatgcggagatctgctcc
gtgttcctgctggatcagaacgagttggtggccaaggtgttcgacgggggcgtggtggat
gatgagagctacgagatccgcatcccggccgaccagggcatcgcgggccacgtggcgacc
actggccagatcctgaacatcccggacgcgtacgcgcacccgcttttctaccgcggcgtg
gacgacagcactggcttccgcacgcgcaacatcctctgctttcccatcaagaatgagaac
caggaggtcatcggcgtggccgagctggtgaacaagatcaatggaccttggttcagcaag
ttcgacgaggacctggcgacagccttctccatctattgtggcatcagcatcgcccactcc
ctcctgtacaaaaaagtcaacgaggcccagtatcgcagccacctggccaacgagatgatg
atgtaccacatgaaggtctctgacgacgagtacaccaaacttctgtataacgggatccag
cctgtggctgccattgactccaactttgcgagtttcacctacacccctcgatctctgccc
gaggatgacacgtccatggctatcctgagcatgctgcaggacatgaatttcatcaataac
tacaaaatcgactgcccaacactggcccggttctgtttgatggtgaagaaaggctaccgg
gaccccccctaccacaactggatgcacgccttttctgtctcccacttctgttacctactc
tacaagaacctggagctggcaaactacctcgaggacattgagatcttcgccttgtttatt
tcctgcatgtgtcatgacctggaccacagaggcaccaacaactccttccaggtggcctcg
aaatctgtgctggctgcactctacagctccgagggctctgtcatggagaggcaccacttc
gctcaggccatcgccattctcaacacccacggttgcaacatcttcgaccacttctcccgg
aaggactatcagcgcatgctggacctgatgcgggacatcatcttggccacagacttggca
caccacctccgtatcttcaaggatctccagaagatggctgaagtgggctatgaccgaacc
aacaaacagcaccacagcctcctcctctgcctccttatgacctcctgtgacctctctgac
cagaccaagggctggaagaccacaagaaagattgcagagctgatctacaaagagttcttc
tcccagggagacttggagaaggccatgggcaacaggccgatggagatgatggaccgggag
aaggcctacatccctgagctgcagatcagcttcatggagcacatagcaatgcccatctac
aagcttctgcaggacctgttccccaaggcggcagagctgtatgagcgtgtggcctcaaac
cgtgagcactggaccaaggtgtcccacaagttcaccatccgaggcctcccaagcaacaac
tcactggactttctggatgaggagtacgaggtgcccaagatggatggtgctgggggccct
gtcaatggctgctgcagccttgacgctgagtga
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