Loxodonta africana (African savanna elephant): 100667057
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Entry
100667057 CDS
T04351
Symbol
PLA2G4E
Name
(RefSeq) cytosolic phospholipase A2 epsilon
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00564
Glycerophospholipid metabolism
lav00565
Ether lipid metabolism
lav00590
Arachidonic acid metabolism
lav00591
Linoleic acid metabolism
lav00592
alpha-Linolenic acid metabolism
lav01100
Metabolic pathways
lav04010
MAPK signaling pathway
lav04014
Ras signaling pathway
lav04072
Phospholipase D signaling pathway
lav04217
Necroptosis
lav04270
Vascular smooth muscle contraction
lav04370
VEGF signaling pathway
lav04611
Platelet activation
lav04664
Fc epsilon RI signaling pathway
lav04666
Fc gamma R-mediated phagocytosis
lav04724
Glutamatergic synapse
lav04726
Serotonergic synapse
lav04730
Long-term depression
lav04750
Inflammatory mediator regulation of TRP channels
lav04912
GnRH signaling pathway
lav04913
Ovarian steroidogenesis
lav04921
Oxytocin signaling pathway
lav05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
100667057 (PLA2G4E)
00565 Ether lipid metabolism
100667057 (PLA2G4E)
00590 Arachidonic acid metabolism
100667057 (PLA2G4E)
00591 Linoleic acid metabolism
100667057 (PLA2G4E)
00592 alpha-Linolenic acid metabolism
100667057 (PLA2G4E)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100667057 (PLA2G4E)
04014 Ras signaling pathway
100667057 (PLA2G4E)
04370 VEGF signaling pathway
100667057 (PLA2G4E)
04072 Phospholipase D signaling pathway
100667057 (PLA2G4E)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
100667057 (PLA2G4E)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100667057 (PLA2G4E)
04664 Fc epsilon RI signaling pathway
100667057 (PLA2G4E)
04666 Fc gamma R-mediated phagocytosis
100667057 (PLA2G4E)
09152 Endocrine system
04912 GnRH signaling pathway
100667057 (PLA2G4E)
04913 Ovarian steroidogenesis
100667057 (PLA2G4E)
04921 Oxytocin signaling pathway
100667057 (PLA2G4E)
09153 Circulatory system
04270 Vascular smooth muscle contraction
100667057 (PLA2G4E)
09156 Nervous system
04724 Glutamatergic synapse
100667057 (PLA2G4E)
04726 Serotonergic synapse
100667057 (PLA2G4E)
04730 Long-term depression
100667057 (PLA2G4E)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
100667057 (PLA2G4E)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
100667057 (PLA2G4E)
Enzymes [BR:
lav01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
100667057 (PLA2G4E)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
cPLA2_C2
PLA2_B
C2
Motif
Other DBs
NCBI-GeneID:
100667057
NCBI-ProteinID:
XP_023414478
LinkDB
All DBs
Position
Unknown
AA seq
834 aa
AA seq
DB search
MLQRKMPAWVSHDLPDPCTAKDSRPSTTCAPEEGLSPCHLLTVRVIRMKNVRQADVLSQT
DCFVTLWLPTASCEKLRTKTISNCSNPEWNETFNFQIQSQVKNILELSVCDEDTVTPDDH
LLTVLYDLTKLCFRKKTHVKFPLNPEGMEELEVEFLLEESPSAPETLITNGVLVSRQISH
LEVHAEARRQRKSRKKEGLLVTVHESFEHTQHLLPCLEPCHPDPACFHYPKYFQPRICVE
VPKSHWSCGLCCCRARKSSPVCQPLDCLPDGHIMTLPVGENCELHMKSTDCPDVLDVRLG
YSLCPAELEFLEKRKVVVARALKQVLQLEEDLQADEVPLIAIMATGGGTRSMTSMYGHLL
GLQKLNILNCAAYIAGLSGATWTMATLYQDPEWSSKNLEPAVFEARRHVVKDKLPALFPD
QLLKYKEELRQRSQEGYRVTFNDFWGLLIEACLGDKRNECKLSEQRAALCRGQNPLPIYL
TINVKDDVSNQDFREWCEFSPYEVGLQKYGAFVPTELFGSEFFMGRLTKRIPESQMCYML
GLWSSIFSLNLLDAWNLSHTSEEFFHRWTRERVHDIEDEPLLPEIPKCDANALETTVVIP
GSWLSNTFRDILTHRSFVSEFHNFLRGLQLHTDYLQNGQFSKWKDTVLDGFPNQLTESVN
HLCLLDTAFFVNSCYPPLLRPERKADLIIHLNYCAGSQTKPMKQTCEYCTVQNIPFPRYE
LQEDDDHLKECYLMENPQDPEAPIVAFFPLINGTFQKYKAPGVERSPEELEHGQVDIYGP
KTPYATKELTYTEAAFDKLVKLSEYNILNNSDKLLQALRLAVEKKKRLKGQCPS
NT seq
2505 nt
NT seq
+upstream
nt +downstream
nt
atgctccagaggaagatgcccgcctgggtctcccacgacctgccagacccatgcacagca
aaagacagcagaccctcaaccacctgtgccccagaggagggactgtctccatgccacctg
ctgacagtgagggtcatccggatgaaaaatgtccgtcaggctgacgtgttgagccagaca
gactgctttgtgaccctctggctgcccacagcctcttgtgaaaagctgaggactaagacg
atctccaactgctcaaacccagagtggaatgaaaccttcaacttccagatccagagccaa
gtgaagaacattttagagctgagcgtctgtgatgaagacacagtgacgccagacgaccat
ctcttgacagttctctatgacctcaccaagctctgcttccgaaagaaaacccacgtgaaa
ttcccacttaaccctgagggcatggaggagctggaggtagagttcctgctggaggagagt
ccctctgcacctgagaccctcatcaccaacggtgtcctggtgtcccggcaaatctcccat
ttggaggtacacgcagaagccaggcgtcagaggaagagcaggaaaaaggagggcctcttg
gtgacggtgcacgagtcctttgaacacacccagcacctcttgccctgcctggagccctgc
cacccagaccctgcctgcttccactaccccaagtacttccagccccggatatgtgtggag
gtgcccaagagccactggagctgtgggctttgctgctgcagagcccgcaagagcagccct
gtctgccagcccctggactgccttcccgatggccatatcatgaccctgcctgtgggtgag
aactgtgaattacacatgaagtctacagactgccccgacgtgctggacgtgcggctgggc
tacagcctgtgcccggcagagctggagttcctggagaagcggaaggtggtggtagctcgg
gcgctgaagcaggtgctgcagctggaggaggacctgcaggcagatgaggtaccgctgata
gccatcatggccaccgggggagggacaagatccatgacctccatgtacggccacctgctg
gggctgcagaagctgaacatcctgaactgtgccgcctatatcgccggcctgtcaggggcc
acctggaccatggctaccttgtaccaagaccccgaatggtcctccaaaaacctggagcct
gctgtcttcgaggcccggaggcatgtagtcaaggacaagctaccagctctgttcccagac
cagctccttaaatacaaggaggaactccggcagcgtagccaggaaggctacagggtcacc
tttaatgacttctggggcctgctgatcgaggcctgtctgggagacaagagaaacgaatgc
aaactgtcagagcagcgagccgctctgtgccgaggccagaaccccctgcccatctacctc
accatcaatgtcaaggatgatgtaagcaaccaagacttcagagagtggtgtgagttctcc
ccctacgaggtgggcctgcagaagtacggggccttcgtccccaccgagctcttcggctcc
gagttcttcatggggcggctgacgaagaggatccctgagtcgcaaatgtgctacatgcta
ggtttgtggagcagcatcttctccctgaacctgctggatgcctggaacctgtcccatacc
tcggaggagtttttccacaggtggacgagagagagagtgcatgatattgaagacgagccg
ctcctgcctgaaatccccaaatgtgacgccaacgccctggagaccacggtggtgatccca
gggtcatggctgtccaacactttccgcgacatcctcacccatcggtcctttgtgtctgag
ttccacaacttcctgagggggctgcagctgcacaccgactacctccagaacggccagttc
tccaagtggaaagacacagttctcgacggcttcccaaaccagctgacggagtccgtgaac
cacttgtgcctgctggacactgcgttctttgtcaactcctgctacccaccccttctacgg
ccagagaggaaagctgacctcatcatccacctcaattactgtgccgggtcccagaccaag
cccatgaagcaaacctgtgagtactgcaccgtgcagaacatccccttccccagatatgag
ctgcaagaagacgacgaccatctcaaggaatgctacctgatggagaacccccaggacccc
gaagcccccattgtggctttcttcccgctcatcaatggcaccttccaaaagtacaaggcc
ccaggtgtggagcgaagccctgaagagctggagcatggccaggttgacatttatggtccc
aaaactccctacgccaccaaggagctgacatacacagaagccgcctttgacaagctggtg
aagctgtctgagtacaacatcctgaacaacagcgacaagctccttcaggccctgcgactg
gcggtggagaagaagaaacgcctgaagggccagtgtccctcctga
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