Loxodonta africana (African savanna elephant): 100667785
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Entry
100667785 CDS
T04351
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial isoform X1
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00020
Citrate cycle (TCA cycle)
lav00620
Pyruvate metabolism
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav04934
Cushing syndrome
lav05200
Pathways in cancer
lav05211
Renal cell carcinoma
Module
lav_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lav_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
100667785 (FH)
00620 Pyruvate metabolism
100667785 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100667785 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
100667785 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100667785 (FH)
Enzymes [BR:
lav01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
100667785 (FH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
100667785
NCBI-ProteinID:
XP_003410962
UniProt:
G3SWS6
LinkDB
All DBs
Position
Unknown
AA seq
508 aa
AA seq
DB search
MSRALRFLARQDRLVRPAAPGSAPGLGSSAGLPSRPPNAARMASQNSYRIEYDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPAPVIKAFGILKRAAAEVNQDYGLDPKIASAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAATEVHEVLLPGLQKLHDALDAKSKEFAQIIKIGRTHTQDAVPL
TLGQEFSGYVQQVKYAMTRIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVAALTG
LPFVTAPNKFEALAAHDALVELSGAMNTAACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARL
LGDASVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KGTAIELGYLTAEQFDEWVKPADMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgagccgagcgctccgattcctcgcgcgccaggatcgcctcgtgcggcctgcagcccca
ggctccgctcccggcctcggtagctctgccggcctcccatcccggcccccgaacgctgct
cgaatggcgagccagaattcctatcggatagaatatgacactttcggtgaactcaaggtc
ccaaatgataagtattatggtgcccagacagtgagatccacgatgaactttaagattgga
ggtgtaacagaacgcatgccagccccagttattaaagcttttggcatcttaaagcgagca
gctgctgaagtaaaccaggattatggtcttgatccaaagattgccagtgcaataatgaag
gcagcagatgaggtagctgaaggtaaattaaatgatcattttcctctcgtggtatggcag
actggatcaggaacccagaccaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgttaggaggcgaacttggcagcaagaaacctgtacatcctaatgatcatgttaat
aaaagccagagctcaaacgatacttttcccactgcaatgcacattgccgccgcaacagaa
gtgcatgaagtactgttaccaggattgcagaagctacatgacgctcttgatgcgaaatcc
aaggagtttgcccagatcatcaaaattgggcgtacccatacgcaggatgctgttccactt
actcttggacaggaatttagtggttacgttcaacaagtgaaatatgcaatgacgagaata
aaagctgccatgccgagaatctatgagctcgcagccggaggcactgctgttggtactggc
ttaaatactagaattggctttgcagaaaaggttgctgcaaaagtggctgcactcacaggc
ttgccttttgtcacggctccaaataaatttgaagctctggctgctcacgatgccttggtt
gaactcagtggtgccatgaacactgccgcttgcagtctgatgaagatagcaaatgatatc
cgttttctgggctctggtcctcggtcgggtctgggagaactgatcttgcctgagaatgaa
ccaggaagcagtatcatgccaggaaaggtgaaccccacccagtgtgaagcaatgaccatg
gttgccgcacaagtcatggggaatcacgttgctgttactgttggaggcagcaatggacat
tttgagttgaatgttttcaagccaatgatgattaaaaatgtgttacactcagcaaggctg
ctgggggatgcttcagtttccttcacagaaaactgcgtggtgggaatccaggccaacaca
gaaagaatcaacaagctaatgaatgagtctttaatgttggtgacggcgcttaatccccat
atagggtatgacaaggcagcaaagattgctaagacagcacacaaaaatggatcaacctta
aagggaactgccattgaacttggctatctcacagcagagcagtttgatgagtgggtgaaa
cctgcagacatgctggggccaaagtag
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