Loxodonta africana (African savanna elephant): 100668841
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Entry
100668841 CDS
T04351
Symbol
TOP2B
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
100668841 (TOP2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lav03032
]
100668841 (TOP2B)
03036 Chromosome and associated proteins [BR:
lav03036
]
100668841 (TOP2B)
Enzymes [BR:
lav01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
100668841 (TOP2B)
DNA replication proteins [BR:
lav03032
]
Eukaryotic type
DNA Topoisomerases
100668841 (TOP2B)
Chromosome and associated proteins [BR:
lav03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
100668841 (TOP2B)
Centrosome formation proteins
Centriole proteins
100668841 (TOP2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
100668841
NCBI-ProteinID:
XP_010593853
LinkDB
All DBs
Position
Unknown
AA seq
1543 aa
AA seq
DB search
MWVYDDDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWN
NGKGIPVVEHKVEKVFVPALIFGQLLTSSNYDDEEKKVTGGRNGYGAKLCNIFSTKFTVE
TACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMT
RRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHELANERWDVC
LTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSVKPFQVKNHI
WVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFIKAASNCGIVESILNWVKFKAQ
TQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLDCTLILTEGDSAKSLAVSGLGVIGRDR
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKK
HIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDD
RKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVD
GFKPGQRKVLYTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNN
INLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAMDDNLLKFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQ
ELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEY
HTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILK
EFFDLRLSYYGLRKEWLVGMLGAESSKLNNQARFILEKIQGKITIENRSKRDLIQMLVQR
GYESDPVKAWKEAQEKAAEEEDTQNQHDDSSSDSGTPAGPDFNYLLNMSLWSLTKEKVEE
LIKQRDTKGREVSDVKRKSPSDLWREDLAAFIEELDKVEAQEREDILAGMSGKAIKGKVG
KPKVKKLQLEETMPSPYGRRIVPEITAMKADASKKLLKKKKGDLDTTAVKVEFDEEFSGT
PVEGTGEEALTPSAPINKGPKPKREKKEPGTRVRRTPASAGKSNTKKVKKRNPWSDDESK
SESDLEETEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEELKVKASPI
TNDGEDEFVPSDGLDKDEYTFSPGKPKATPEKPSHDKKSQDFGNLFSFPSYSQKSEDDSA
KFDSNEEDSASVFSPSFGLKQTDKVPSKTAAAKKGKPSSDITPKPKRTPKQKKVETVNSD
SDSEFGVPKKTAAPKGKGRGAKKRKASGSENEGDYNPGRKTSKTTASKKPKKSSFDQDSD
VDIFPSDFASEPPSLPRAGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4632 nt
NT seq
+upstream
nt +downstream
nt
atgtgggtgtatgatgatgatgtaggaatgaattgcagagaggttacctttgtgccaggt
ttatacaagatctttgatgaaattttggttaatgcagctgacaataagcagagggataag
aacatgacctgtattaaagtttctattgatcctgaatctaacataataagcatttggaat
aatggaaaaggcattccagtggtagaacataaagtagagaaagtatttgttcctgcttta
atttttggacaacttttaacatccagtaattatgacgatgaagagaaaaaagttacaggt
ggtcgcaacggttatggtgcaaaactttgtaatattttcagtacaaagtttacagtagaa
acggcttgcaaggagtacaaacatagttttaaacagacatggatgaataatatgatgaag
acttctgaagccaaaattaaacatttcgatggtgaagattacacatgcataacattccaa
ccagatctgtccaaatttaagatggagaaacttgacaaggatattgtggccctcatgacc
agaagagcctatgacttggcaggctcctgcaaaggtgtcaaagtcatgtttaatggaaag
aaattgcctgtaaatggatttcgcagttacgtagatctttatgtaaaagacaaattggat
gaaaccggggtggccctgaaagttattcatgaacttgcaaatgaaagatgggatgtttgt
ctcactttgagtgaaaaaggatttcagcaaattagctttgtaaatagtattgcaactaca
aaaggtggacgacacgttgattacgtagtggatcaagttgttggtaaattgattgaagtg
gttaagaaaaagaacaaagctggggtatcagtgaaaccatttcaagtaaaaaaccatata
tgggtttttattaattgccttattgaaaatccaacttttgattctcagactaaggaaaat
atgactctgcaacccaaaagttttgggtccaaatgccagctgtcagaaaaatttattaaa
gcagcttctaactgtggcattgtggaaagcatcctgaactgggtgaagtttaaggctcag
actcagctgaacaagaagtgttcatcagtgaagtacagtaaaatcaaaggtattcctaaa
ctggatgatgctaacgatgctggtggcaaacattccctggattgtacactgatattgaca
gagggagactctgccaaatcgctggctgtgtctggattaggtgtgattgggcgagacaga
tacggagtctttccactcaggggtaaaattctcaatgtacgggaagcttctcataaacag
atcatggaaaatgcagaaataaacaatattattaaaatagttggtctacaatacaagaaa
agttatgatgatgcagaatctctgaaaactttacgctacggaaagattatgattatgact
gatcaggatcaagatggttctcatataaaaggcctgctcattaatttcatccaccacaat
tggccatcacttttgaagcacggttttcttgaagagttcattactcctattgtaaaggcg
agcaaaaataaacaggaactctccttctacagtattcctgaatttgatgagtggaaaaag
catatagaaaaccagaaagcatggaaaataaaatactacaaagggttgggtaccagtaca
gctaaagaagcaaaggagtattttgccgatatggaaaggcatcgtatcttatttagatat
gctggtcctgaagatgatgctgccattaccttggcgttcagtaagaagaagattgatgac
agaaaagaatggttaaccaattttatggaagatcggagacagcgtaggttacatggctta
ccagagcaatttttgtatggtacagcaacaaagcatttgacttacaatgatttcatcaac
aaggaattgattctcttctcaaactcagacaacgaaaggtctataccatctcttgttgat
ggctttaaaccaggccaacggaaagtattatatacctgtttcaagaggaatgataaacgt
gaagtgaaagttgcccagttggctggatctgttgctgagatgtctgcctatcatcatgga
gaacaagcattaatgatgactattgtgaatttggctcagaactttgtgggaagtaacaac
attaacttacttcagcctattggtcagttcggaactcggcttcatggtggcaaagatgct
gcaagccctcgttatattttcacaatgttaagctctttagcaagactgcttttccctgcc
atggatgacaacctgcttaagttcctttatgatgataatcaacgtgtagagcctgagtgg
tatattcctataattcccatggttttaataaatggtgctgagggaattggtaccggatgg
gcttgtaaactccccaactatgatgctagggaaattgtgaacaatgtcagacgaatgctg
gatggcttggatcctcatcccatgcttccaaactacaaaaactttaaagggacaattcaa
gagcttggtcaaaaccaatatgcagtcagtggtgaaatatttgtggtggataggaacacg
gtagagattacagagctccccgttagaacttggacacaggtatacaaagagcaggttttg
gaacctatgctaaatgggacagacaaaacaccagcattaatttctgactataaagaatat
catactgatacaactgtgaaatttgtggtgaaaatgactgaagagaaacttgcacaagca
gaagctgctggattgcacaaagtttttaaacttcaaactactcttacgtgtaattctatg
gtactctttgatcatatgggatgtctgaagaagtatgaaactgtgcaggacattttgaaa
gaattctttgatttacgattaagttattatggtttacggaaggagtggcttgtaggaatg
ttgggagctgaatcttcaaagcttaataatcaagctcgtttcattttagagaagatacaa
gggaaaattactatagagaataggtcaaagagagatttgattcaaatgttagtccagaga
ggttatgaatctgacccagtgaaagcctggaaagaagcacaagaaaaggcagcggaagag
gaagacacacaaaaccagcatgatgacagttcctcggattcaggaactcctgcaggccct
gattttaactatcttttaaatatgtctctgtggtctcttactaaggaaaaagttgaagaa
ctgattaaacagagagatacaaaaggacgagaggtcagtgatgtgaaaagaaaatctcct
tcagatctttggagagaagatttggcagcattcattgaagaactagataaagtggaagcg
caagaacgagaagatattctggctgggatgtctggaaaagcaataaaaggtaaagttggc
aaacctaaagtgaagaaacttcagttggaagagacaatgccttcaccttacggcagaaga
atagttcctgagattactgctatgaaggcagatgccagcaaaaagttgctgaagaagaaa
aagggtgacctggatactacagctgtaaaagtggaatttgatgaagaattcagtggaaca
ccagtagaagggacaggagaagaggcactgactccgtcagctcctataaataaaggtccc
aaacccaaaagagagaaaaaggagcctggtaccagggtgagaagaacacctgcatcagct
gggaaatccaatacaaagaaagtaaagaaaagaaatccttggtcagacgatgagtccaag
tcagaaagtgacttggaagaaacagagcctgtggttattccaagagattctttgcttagg
agagcggctgccgaaagacccaagtacacttttgatttctcagaagaggaggatgatgat
gctgatgatgacgatgacaataatgatttagaggagttgaaagttaaagcatcccccata
acaaatgatggagaagatgaattcgttccttcagatggcttagataaagatgagtataca
ttctcaccgggcaaaccaaaagctaccccagagaagccttcgcatgacaaaaaaagtcag
gattttgggaaccttttctcatttccttcatactctcagaagtcagaagacgattcggct
aaatttgacagtaatgaagaagattctgcctctgtgttttcaccatcatttggtctgaaa
caaacagataaagttccaagtaaaacagcagctgctaaaaagggcaaaccatcttcagat
ataacccctaagcctaagagaacccccaagcagaagaaagtagagaccgtaaactctgac
tcggattcagaatttggtgttccaaagaagactgcggcacccaaaggtaaaggtcgaggg
gcaaagaaaaggaaagcatctggctctgaaaatgaaggtgattataaccctgggaggaaa
acatccaaaaccacggcaagcaagaagccgaagaaatcatcttttgatcaggattcagat
gtggacatcttcccgtcagacttcgcttctgaaccaccgtctctgccacgagccggtagg
gctagaaaagaagtaaaatattttgcagagtctgatgaagaagaagatgtggatttcgca
atgtttaattaa
DBGET
integrated database retrieval system
