Loxodonta africana (African savanna elephant): 100668912
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Entry
100668912 CDS
T04351
Symbol
NOS3
Name
(RefSeq) LOW QUALITY PROTEIN: nitric oxide synthase, endothelial
KO
K13242
nitric-oxide synthase, endothelial [EC:
1.14.13.39
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00220
Arginine biosynthesis
lav00330
Arginine and proline metabolism
lav01100
Metabolic pathways
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04066
HIF-1 signaling pathway
lav04071
Sphingolipid signaling pathway
lav04151
PI3K-Akt signaling pathway
lav04370
VEGF signaling pathway
lav04371
Apelin signaling pathway
lav04611
Platelet activation
lav04915
Estrogen signaling pathway
lav04921
Oxytocin signaling pathway
lav04926
Relaxin signaling pathway
lav04931
Insulin resistance
lav04933
AGE-RAGE signaling pathway in diabetic complications
lav05415
Diabetic cardiomyopathy
lav05417
Lipid and atherosclerosis
lav05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09105 Amino acid metabolism
00220 Arginine biosynthesis
100668912 (NOS3)
00330 Arginine and proline metabolism
100668912 (NOS3)
09130 Environmental Information Processing
09132 Signal transduction
04370 VEGF signaling pathway
100668912 (NOS3)
04371 Apelin signaling pathway
100668912 (NOS3)
04066 HIF-1 signaling pathway
100668912 (NOS3)
04020 Calcium signaling pathway
100668912 (NOS3)
04071 Sphingolipid signaling pathway
100668912 (NOS3)
04022 cGMP-PKG signaling pathway
100668912 (NOS3)
04151 PI3K-Akt signaling pathway
100668912 (NOS3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
100668912 (NOS3)
09152 Endocrine system
04915 Estrogen signaling pathway
100668912 (NOS3)
04921 Oxytocin signaling pathway
100668912 (NOS3)
04926 Relaxin signaling pathway
100668912 (NOS3)
09160 Human Diseases
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100668912 (NOS3)
05418 Fluid shear stress and atherosclerosis
100668912 (NOS3)
05415 Diabetic cardiomyopathy
100668912 (NOS3)
09167 Endocrine and metabolic disease
04931 Insulin resistance
100668912 (NOS3)
04933 AGE-RAGE signaling pathway in diabetic complications
100668912 (NOS3)
Enzymes [BR:
lav01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
1.14.13.39 nitric-oxide synthase (NADPH)
100668912 (NOS3)
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Motif
Pfam:
NO_synthase
FAD_binding_1
Flavodoxin_1
NAD_binding_1
Motif
Other DBs
NCBI-GeneID:
100668912
NCBI-ProteinID:
XP_023403844
LinkDB
All DBs
Position
Unknown
AA seq
1219 aa
AA seq
DB search
MGNLKSVGQEPRPPCGLGLGLGLGLCGKQGPASPASEPSWAPAPVPLPAPDHSPPLARPP
EGPKFPRVKNWEVGSITYDTLSAQAQQDGPCTPRHCLGSLVYPRKLQSRPSPHPAPPERL
LSQARDFIHQYYSSIKRSGSQAHEQRLQEVEDEVAATGTYQLRESELVFGAKQAWRNAPR
CVGRIQWGKLQVFDARDCSSAQEMFTYICNHIKYGTNRGNLRSAITVFPQRAPGRSDFRI
WNSQLVRYAGYRQQDGSVLGDPANVEITELCIQHGWTPGNGRFDVLPLLLQAPDEPPEVF
PLPPELVLEVPLEHPTLEWFAALGLRWYALPAVSNMLLEIGGLEFTAAPFSGWYMSTEIG
TRNLCDPHRYNILEDVAVCMDLDTRTTSSLWKDKAAVEINLAVLHSFQLAKVTIVDHHAA
TASFMKHLENEQKARGGCPADWAWIVPPISGSLTPVFHQEMVNYFLSPAFHYQPDPWKGS
AAKGTGITRKKTFKEVANAVKISASLMGTVMAKRVKATILYGSETGRAQSYAQQLGRLFR
KAFDPRVLCMDEYDVVSLEHETLVVVVTSTFGNGDPPENGESFAAALMEMTSPYNSSPRP
EQHKSYKMRFNSVSCSDPLVASWRRKRKESSNTDSAGALGTLRFCVFGLGSRAYPHFCAF
ARAVDTRLEELGGERLLQLGQGDELCGQEEAFRSWAQAAFQASCETFCVGEDAKAAARDI
FSPKWSWKRQRYRLSAQAKDLQLLPGLIHVHRRKMFQATVLSVENLQSSKSTRATILVRL
DTAEQQGLQYQPGDHVGVCPPNRPGLVEALLSRVEDPPPPSEPIAVEQLEKGSPGGPPPS
WVRDPRLPPCTLRQALTYFLDITSPPSPRLLRLLSTLAEEPSEQQELETLSQDPRRYEEW
KWFRCPTLLEVLEQFPSVALPAPLLLTQLPLLQPRDYSVSSAPSAHPGEIHLTVAVLAYR
TQDGLGPTCTMGGLFHVAEANFKGWETPLPLLSIRRGKRGQLPGAEVSPTRAPSFRLPPD
PSLPCILVGPGTGIAPFRGFWQERLNDIESKGLQPAPMTLVFGCRCSQLDHLYREEVQDA
QQRGVFGRVLTAFSREPDSPKTYVQDLLRTELAAEVHRVLCLERGHMFVCGDVTMATSVL
QTVQRILATEGNMELDEAGDVIGVLRDQQRYHEDIFGLTLRTQEVTSRIRTQSFSLQERQ
LRGAVPWAFDPPGPDTPGP
NT seq
3660 nt
NT seq
+upstream
nt +downstream
nt
atgggcaacttgaagagtgtgggccaggagcctaggcctccctgcgggctggggctgggg
ctgggccttgggctgtgcggcaagcagggcccagcctccccagcctctgagcccagctgg
gcaccagcaccagtgcccctacctgcgcctgaccacagccccccactagcccggcctcca
gagggacccaagttccctcgtgtgaagaactgggaagtggggagcatcacctatgatacc
ctgagtgcccaggcacagcaggatggaccctgcaccccaagacactgcctgggctccctt
gtatatccgcggaaactgcagagccggccctccccgcaccctgcaccccctgagaggctt
ctgagtcaggcccgggacttcatccaccagtactacagctccatcaagaggagtggctcc
caggcccacgagcagcgtcttcaggaggtagaagacgaggtggcagccacaggcacctac
cagcttcgggagagcgagctggtgttcggggccaagcaggcctggcgcaatgccccccga
tgcgtgggccgcatccagtgggggaagctgcaggtatttgatgcgcgggactgtagctct
gcgcaggagatgttcacctacatctgcaaccacatcaagtatggcaccaaccggggtaac
cttcgctctgccatcaccgtgttcccccaacgtgcccctggccgcagtgatttccgaatc
tggaacagccagctggtgcgctatgcaggctacagacagcaggatggctctgtgctgggg
gaccctgccaacgtggagatcaccgagctctgcatccagcatggctggaccccaggaaac
ggccgatttgacgtgctgcccctgctgctccaggccccagatgagcccccagaggtcttc
cctttgccccctgaactggtccttgaggtgcccctggagcaccccacgttggagtggttc
gcagcactgggcctgcggtggtatgccctcccagcagtgtccaacatgctgctggaaatc
gggggtctggagttcactgcagctcctttcagcggctggtacatgagcactgagattggc
actcggaacctgtgtgatccccaccgctacaacattctagaggatgtggctgtctgcatg
gacctggacacacggaccacctcgtccctgtggaaagataaggcagctgtggaaattaac
ttggctgtgctgcacagtttccagctagccaaagtgaccattgtggaccaccacgccgcc
acagcctccttcatgaagcacctggaaaatgagcagaaggcgaggggagggtgccctgct
gactgggcatggatcgtaccccccatctcgggcagcctcacacctgtcttccatcaggag
atggtcaactatttcctgtcccctgccttccactatcagccagatccctggaagggaagt
gcagccaagggtacaggcatcaccaggaagaagacctttaaggaagtggctaatgcagtg
aagatctctgcctcgctcatgggcactgtgatggctaagcgagtgaaggcgacaatcctg
tatggctctgagactggccgggcccagagctacgcacagcagcttgggaggctcttccgg
aaggctttcgatccccgggtcctgtgcatggatgagtatgacgtggtgtccctcgagcac
gagacactggtggtggtggtgaccagcacatttgggaacggtgatccacctgagaatggc
gagagctttgcagccgccctgatggaaatgaccagcccctacaacagctcccctcggcca
gaacagcacaagagctacaaaatgcgcttcaacagtgtctcctgctcagaccccctggtc
gcctcctggcggcggaagaggaaggagtccagtaacacggacagtgcgggggcgctgggc
accctcaggttctgtgtgttcgggctgggctcccgggcatatccccacttctgcgctttc
gcgcgcgcagtggacacgcggttggaagagctgggtggagagcggctgctgcagctgggc
cagggggatgagttgtgcggccaggaggaagccttccgtagctgggcccaggccgccttt
caggcctcctgtgagactttctgtgtgggggaagatgccaaggctgctgcccgggacata
ttcagtcccaaatggagctggaagcgccagagataccggctgagtgcccaggccaaggac
ctccagctgctgccaggcctgatccacgtacacaggcggaaaatgttccaagctacagtc
ctctcagtggaaaatctgcaaagcagcaagtctacccgggccaccatcctggtgcgccta
gacactgcagagcagcaggggctgcagtaccagcctggggaccatgtcggtgtctgccca
cccaaccggcctggcctggtggaggcgctgctgagccgtgtggaggacccaccgccgccc
tctgagcccattgcagtggagcagctagagaagggcagtcctggtggcccaccccccagc
tgggtacgggaccccagactgcccccgtgcacactgcgccaggctctgacctacttcctg
gacatcacatccccacccagccctcgactccttcgactgctcagcactctcgctgaagag
cccagcgaacagcaggagctggagaccctcagccaggaccccaggcgctatgaggagtgg
aagtggttccgctgccccacgctactggaagtgctggagcagtttccgtcagtggcattg
cctgctcccctgctcctcacccagctgcctctgctccagccacgggactactcagtcagc
tcagcacccagtgcccacccaggagagatccacctcacagtagctgtcctggcataccgg
acccaggatggcctgggccccacctgcactatgggaggcctgttccacgtggctgaagcc
aacttcaaaggctgggagactccgttgcccctgctttccatcagaaggggtaaacggggg
caactgcctggggcagaagtctctccaaccagggctccctccttccgactgccgcctgat
cccagcttgccctgcatccttgtgggacctggcacaggcattgcccccttccggggattc
tggcaggagagactgaacgacattgaaagcaaagggttgcagcccgcccccatgaccttg
gtgtttggctgccgatgctcccagcttgaccacctctaccgtgaggaggtgcaagacgcc
cagcagcgcggggtgtttggccgtgttctcaccgccttctcccgggaacccgacagcccc
aagacttacgtgcaggacctcctccggactgagctggctgccgaggtgcaccgcgtgctg
tgcctcgagcggggccacatgttcgtctgcggcgatgtcaccatggcgaccagcgtcctg
cagaccgtgcagcgcatcctggcgactgagggcaacatggagctggacgaggccggcgat
gtcatcggcgtgctgcgggatcagcaacgctatcacgaagacattttcggactcaccctg
cgcacccaggaggtgacaagccgcatacgcacccagagcttttccttgcaagagcggcag
ctccggggtgcagtgccctgggcattcgaccctcctggcccagacacccccggcccctga
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integrated database retrieval system
