Loxodonta africana (African savanna elephant): 100670374
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Entry
100670374 CDS
T04351
Symbol
SHMT1
Name
(RefSeq) serine hydroxymethyltransferase, cytosolic
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00260
Glycine, serine and threonine metabolism
lav00630
Glyoxylate and dicarboxylate metabolism
lav00670
One carbon pool by folate
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01230
Biosynthesis of amino acids
lav01240
Biosynthesis of cofactors
lav01523
Antifolate resistance
lav04981
Folate transport and metabolism
Module
lav_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100670374 (SHMT1)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100670374 (SHMT1)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100670374 (SHMT1)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100670374 (SHMT1)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100670374 (SHMT1)
Enzymes [BR:
lav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100670374 (SHMT1)
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Motif
Pfam:
SHMT
DegT_DnrJ_EryC1
Aminotran_1_2
Motif
Other DBs
NCBI-GeneID:
100670374
NCBI-ProteinID:
XP_003420713
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All DBs
Position
Unknown
AA seq
484 aa
AA seq
DB search
MATPISGVHQDADLWASHTKMLAEPLRDNDIEVYNIIKKESNRQRVGLELIASENFASRA
VLEALGSCLNNKYSEGYPGQRYYGGTEFIDELELLCQKRALQAYNLDPQCWGVNVQPYSG
SPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGY
INYDQLEQNARLFHPKLIIAGVSCYSRNLDYSRLRKIADDNGAYLMADMAHISGLVAAGV
VPSPFEYCHVVSTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKEILYNLESLINAAVFPGL
QGGPHNHAIAGVAVALKQAMTPEFIAYQHQVVANCKALSQALMELGYSIVTGGSDNHLIL
VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGFLEEDFHQ
VAHFIHRGIELTLQIQKDIGAKATLKEFKEKLAGDEKHQTAIRALREDVENFASLFPLPG
LPDF
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggcgactcccatcagtggtgttcaccaggatgccgacctctgggcctcgcacactaag
atgctggcagagcccctgagagacaatgacatcgaggtttacaacatcattaagaaggag
agtaaccggcagagggttggattggagctgattgcctcagagaatttcgccagccgagct
gttctggaggccctgggctcttgcttaaataacaaatactctgaggggtacccaggccag
aggtactatggcgggacggagttcattgatgagctggagcttctgtgccagaaacgggcg
ctgcaggcttacaacctggacccccagtgctggggggtcaatgtccagccctactcaggc
tcccctgccaactttgcggtgtacactgccctggtggagccccacgggcgcatcatgggc
ctggacctgcccgacgggggccacctgacccacgggttcatgactgacaagaagaagatc
tcggccacatccatcttttttgaatccatgccttataaggtgaaccccgacactggctat
atcaactatgaccagctggagcagaatgcccgccttttccacccaaagctgatcattgca
ggtgtcagctgctactcccgaaacctggactactcccgtctgaggaagattgccgatgat
aacggggcgtatctcatggcagacatggcacacatcagtgggctggtggcagctggcgtg
gtgccctccccttttgaatactgccacgtggtgtccaccaccacccacaagactctgcga
ggctgccgggctggcatgatcttctacaggaaaggagtgcgcagtgtggaccccaagact
ggcaaagagattctgtacaacctggagtcgctcatcaatgctgccgtcttcccgggcctc
cagggaggtccccacaaccacgccattgctggggttgctgtggccctgaagcaagccatg
actccggagttcatagcttatcagcaccaggtggtggccaactgcaaggccctgtcccag
gccctaatggagctgggctacagcatagtgacaggtggttctgacaaccatttgatcctt
gtcgatctccgttccaaaggcactgatggtggaagggctgagaaggtgctagaagcctgt
tctattgcctgtaacaagaacacctgcccaggtgacaaaagtgcactgcggcccagtgga
ctaagactggggaccccagcactgacatcccgaggattcttggaagaagacttccaccaa
gtagcccactttatccacagagggatagagctgacactgcagattcagaaggacatcggt
gccaaggctaccctgaaggaattcaaggagaagctagcaggcgatgagaagcaccagact
gccatcagggctctccgggaggatgtggagaactttgcttccctcttccctctgcctggc
ctgcctgacttctga
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