Loxodonta africana (African savanna elephant): 100670753
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Entry
100670753 CDS
T04351
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04148
Efferocytosis
lav04260
Cardiac muscle contraction
lav04261
Adrenergic signaling in cardiomyocytes
lav04380
Osteoclast differentiation
lav04919
Thyroid hormone signaling pathway
lav04972
Pancreatic secretion
lav05010
Alzheimer disease
lav05017
Spinocerebellar ataxia
lav05022
Pathways of neurodegeneration - multiple diseases
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
lav05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100670753 (ATP2A2)
04024 cAMP signaling pathway
100670753 (ATP2A2)
04022 cGMP-PKG signaling pathway
100670753 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100670753 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100670753 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
100670753 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
100670753 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
100670753 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
100670753 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100670753 (ATP2A2)
05017 Spinocerebellar ataxia
100670753 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
100670753 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100670753 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
100670753 (ATP2A2)
05414 Dilated cardiomyopathy
100670753 (ATP2A2)
05415 Diabetic cardiomyopathy
100670753 (ATP2A2)
Enzymes [BR:
lav01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100670753 (ATP2A2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Hydrolase
Hydrolase_3
Cation_ATPase_N
HAD
Motif
Other DBs
NCBI-GeneID:
100670753
NCBI-ProteinID:
XP_003420398
LinkDB
All DBs
Position
Unknown
AA seq
1012 aa
AA seq
DB search
MLLGEFLHFTELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWFEEGEETITAFV
EPFVILLILIANAIVGVWQERNAENAIEALKEYEPEMGKVYRQDRKSVQRIKAKDIVPGD
IVEIAVGDKVPADIRLTSIKSTTLRVDQSILTGESVSVIKHTDPVPDPRAVNQDKKNMLF
SGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQLSKVISLICI
AVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKK
NAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTY
APIGEVHKDDKPVRCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLV
EKMNVFDTELKGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMSVYCTPNKPSRTSMS
KMFVKGAPEGVIERCTHIRVGSTKIPITPGVKQKIMSVIREWGSGSDTLRCLALATHDNP
MRREEMNLEDSANFIKYETNLTFVGCVGMLDPPRSEVASSVKLCRQAGIRVIMITGDNKG
TAVAICRRIGIFRQDEDVTSKAFTGREFDELSPSAQRDACLTARCFARVEPSHKSKIVEF
LQSFDEITAMTGDGVNDAPALKKSEIGIAMGSGTAVAKTASEMVLADDNFSTIVAAVEEG
RAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFN
PPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCYVGAATVGAAAWWFIAADGGPRVTFYQL
SHFLQCKDDNPDFEGVDCAVFESPYPMTMALSVLVTIEMCNALNSLSENQSLLRMPPWEN
IWLVGSICLSMSLHFLILYVEPLPLIFQITPLNLTQWLMVLKISLPVILMDETLKFVARN
YLEPGKECVQPARPCSLSACTDGISWPFVLLVVPLVVWVYSTDTNFTDMFWS
NT seq
3039 nt
NT seq
+upstream
nt +downstream
nt
atgttgcttggcgaatttcttcattttacagagttaccggctgaagaaggaaaaaccttg
ctagaacttgtgattgagcagtttgaagacttactagttagaattttattgctggcagca
tgtatatcttttgttttggcttggtttgaagaaggtgaagaaacaattacagcctttgta
gaaccctttgtaattttacttatattaatagccaatgcaattgtgggtgtatggcaggaa
agaaatgctgaaaatgcaattgaagcccttaaggagtatgagcctgaaatgggcaaagtg
tatcgacaggacagaaagagtgtacagcgaattaaagctaaagacatagttcctggtgat
atcgtagaaatcgctgttggtgacaaagttccagctgatataagactaacttctatcaaa
tctacaactctgagagtagaccagtcgattcttacaggtgaatctgtctctgtcatcaag
cacacggaccctgtccctgacccacgggctgtcaaccaagataagaagaacatgctcttt
tctggcacaaacattgctgctggaaaggccatgggagtggtggtggcaactggagttaac
actgagattggcaagatccgggatgaaatggtggcaacggagcaagagagaacacccctc
cagcagaaactggatgagtttggagaacagctgtccaaagttatctccctcatttgtatt
gccgtctggatcataaacattgggcatttcaatgatcccgttcacggaggttcttggatc
agaggtgctatctactactttaaaattgcggtggccctggctgtcgcagccattcccgaa
ggtctgcctgctgtcatcaccacctgcctggctcttggaacacgcagaatggcaaagaaa
aatgccattgttcgaagccttccctcggtggaaacccttggttgtacttctgttatctgc
tcagacaagactggtacacttacgacaaaccagatgtcggtctgcaggatgttcattctg
gacagggtcgaaggcgatacttgttctcttaatgagttcaccataactggatcaacatat
gcacctataggagaagtgcataaagatgataagccagtaagatgtcatcagtatgatggt
cttgtagaattagcaacaatctgtgctctttgtaatgactctgctttggattacaatgag
gcaaagggcgtgtatgaaaaagttggagaagctacagagactgcactcacgtgtctggta
gagaagatgaatgtattcgatacggaattgaagggtctttctaaaatagaacgtgcaaac
gcctgcaactcggtcattaaacagttgatgaaaaaagaatttaccctagagttttcacgc
gatagaaaatcaatgtcggtttattgcacaccaaacaaaccaagccgaacatccatgagc
aagatgtttgtgaagggcgctcccgagggtgtcattgagaggtgtacccacattcgagtt
ggaagcacgaagattcccataactccgggggtcaagcagaagatcatgtctgttattcgg
gagtggggcagtggcagcgacaccctgcgctgcctggctctggccactcacgacaaccca
atgaggagagaagagatgaaccttgaggactctgccaacttcatcaagtatgagaccaat
ctgaccttcgttggctgcgtgggcatgctggaccccccgagaagtgaagtggcctcgtca
gtgaagttgtgcaggcaggcaggcatccgcgtcatcatgatcacgggggacaacaagggt
accgctgtggccatctgtcgccggattggcatcttccggcaggatgaggatgtgacgtcg
aaggccttcacaggccgggagtttgacgagctcagtccctcagcgcagagggacgcctgc
ttgacggctcgctgcttcgctcgtgtggagccttcccacaagtctaaaatcgtagagttt
cttcagtcttttgatgagattacagctatgactggggacggtgtgaacgatgcgcctgct
ctgaagaagtctgagatcggcatcgccatgggctccggcaccgccgtggccaagactgcc
tctgagatggtcttggctgacgacaacttctccaccattgtggcggccgtcgaggaggga
cgggcaatctacaacaacatgaagcagttcatccgctacctcatctcgtccaacgtcggc
gaggtcgtctgtattttcctgacagcggccctgggttttcctgaggctttaattcctgtc
cagctgctctgggtcaacctggtgacagacggcctacccgctaccgccctgggcttcaac
cctcctgatctggacatcatgaataagccgccccggaaccccaaggagccactgatcagt
gggtggctctttttccgttacctcgcaattggctgttatgttggtgccgctaccgtgggc
gctgctgcatggtggtttatcgctgctgacggcggtccccgggtcaccttctaccagctg
agtcacttcctacagtgtaaagacgacaaccctgattttgaaggagtggattgtgcagtc
tttgaatccccgtacccgatgacaatggcactttctgttctcgtaaccatagagatgtgt
aatgccctcaacagcttgtctgaaaaccagtccttgctgaggatgcccccctgggagaac
atctggctcgtgggctccatctgcctgtccatgtccctccacttcctcatcctctacgtg
gagcccttgcctcttatcttccagatcacaccgctgaacttgacccagtggctgatggtg
ctgaaaatctccctgcccgtgatcctcatggacgagaccctcaagttcgtggcgcgcaac
tacctggagcctggtaaagagtgtgtgcagccggcgcggccatgctcgctctcagcgtgc
accgacggcatctcctggccttttgtgctgctcgtagtgccgctggtggtctgggtctat
agcacagacactaacttcaccgatatgttctggtcttga
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