Loxodonta africana (African savanna elephant): 100671775
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Entry
100671775 CDS
T04351
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X6
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04148
Efferocytosis
lav04260
Cardiac muscle contraction
lav04261
Adrenergic signaling in cardiomyocytes
lav04380
Osteoclast differentiation
lav04919
Thyroid hormone signaling pathway
lav04972
Pancreatic secretion
lav05010
Alzheimer disease
lav05017
Spinocerebellar ataxia
lav05022
Pathways of neurodegeneration - multiple diseases
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
lav05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
100671775 (ATP2A3)
04024 cAMP signaling pathway
100671775 (ATP2A3)
04022 cGMP-PKG signaling pathway
100671775 (ATP2A3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
100671775 (ATP2A3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
100671775 (ATP2A3)
09153 Circulatory system
04260 Cardiac muscle contraction
100671775 (ATP2A3)
04261 Adrenergic signaling in cardiomyocytes
100671775 (ATP2A3)
09154 Digestive system
04972 Pancreatic secretion
100671775 (ATP2A3)
09158 Development and regeneration
04380 Osteoclast differentiation
100671775 (ATP2A3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
100671775 (ATP2A3)
05017 Spinocerebellar ataxia
100671775 (ATP2A3)
05022 Pathways of neurodegeneration - multiple diseases
100671775 (ATP2A3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100671775 (ATP2A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
100671775 (ATP2A3)
05414 Dilated cardiomyopathy
100671775 (ATP2A3)
05415 Diabetic cardiomyopathy
100671775 (ATP2A3)
Enzymes [BR:
lav01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
100671775 (ATP2A3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF3106
Motif
Other DBs
NCBI-GeneID:
100671775
NCBI-ProteinID:
XP_010594815
LinkDB
All DBs
Position
Unknown
AA seq
999 aa
AA seq
DB search
MEAAHLLPAADVLRRFAVTAECGLSPAQVTDARERYGPNELPTEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAISDARAVNQDKKNMLFSGTNIASGKAVGVAVATGLHTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSRAISVICVAVWVINIGHFADPVHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGSCRLHEFTISGTTYTPEGEVRQGEKPVRCGEFDSLVELATICALC
NDSALDYNEAKGIYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVIKQLMR
KEFTLEFSRDRKSMSVYCTPIRPGSAAQGSKMFVKGAPESVIERCISVRVGSRTVPLNTA
SRAQILAKIRDWGSGSDTLRCLALATRDMPPRKEDMQLDDCSKFAQYETDLTFVGCVGML
DPPRPEVAACIARCCQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVVGRAYTGREFDD
LSPEQQRHACQTARCFARVEPAHKSRIVEYLQSFNEVTAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVSAVEEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKPPRNPHEALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPHVTFYQLRNFLKCSKENPLFADEVDCKVFESRFPTTM
ALSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHFLILLVPPLPLIFQV
TPLSGRQWVVVLQISLPVILLDEALKYLSRNHMDEKGQK
NT seq
3000 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgcacctgctcccggccgccgacgtgctgcgccgctttgcggtgaccgcc
gagtgcggcctgagcccggcgcaggtgaccgacgcgcgggagcgctacggccccaacgag
ctcccgacggaggaagggaagtccctgtgggagctggtgctggagcagtttgaagacctc
ctggtgcgcatcctgctgctggccgccctggtctccttcgtcctggcctggttcgaggaa
ggtgaggagaccacgacagccttcgtggagcctctggtcatcatgctgatcctcgtggcc
aatgcgatcgtgggcgtatggcaggaacgcaatgctgagagtgccattgaggccctaaag
gaatacgagcctgagatgggcaaggtgatccgctcagaccgcaagggtgtgcagaggatc
cgtgcccgggacattgtccccggagatattgtggaagtggcagtcggggacaaagtgcct
gctgacctccgcctcattgagatcaagtccaccacgctgcgagtggaccagtccatcctg
acaggtgaatctgtgtcggtgaccaagcacacagatgccatctcagacgcgagagctgtg
aaccaggacaagaagaacatgctgttttctggcaccaacattgcgtcaggcaaggcggtg
ggcgtagctgtggccacaggcctgcacacggagctgggcaagatccggagccagatggcg
gcggtggagccggagcggacaccgctgcagcgtaagctggatgagttcgggcggcagctg
tcccgtgccatctctgtgatctgcgtggctgtgtgggtcatcaacatcggccattttgcc
gacccagtccacggcggctcctggctccgtggtgccgtctactacttcaagattgctgtg
gccttggctgtggccgccatccctgagggcctcccggctgtcatcactacatgcctggca
ctgggcacccggcgcatggcacgcaagaatgccatcgtgcggagcttgccctctgtggag
accttgggctgcacctcagtcatctgctctgacaagaccggcacactcaccaccaaccag
atgtccgtctgccggatgttcgtggtggccgaggccgaggctggctcctgccgtttgcac
gaattcaccatctcgggtaccacctacaccccggagggcgaagtgcggcagggagaaaag
cctgtgcgctgtggagagtttgacagtttggtggagctggcgaccatctgtgcgctgtgc
aatgactcggcgctggactacaacgaggccaagggcatatatgagaaagtgggagaggct
acggagacagctttgacttgcctggtggagaagatgaacgtgtttgacaccgacctccag
gccctgtcccgagtggagcgagccggtgcctgcaacacagtcatcaaacagctgatgcgg
aaggagttcacccttgagttctcccgagaccggaagtccatgtcagtgtactgcacgccc
atccgccctggctcagcagcccagggcagcaagatgtttgtgaagggggctcctgaaagt
gtgatcgagcgctgcatctcagtccgcgtgggaagccgcacagtacctctgaacactgcc
tccagggcgcagatcctggcaaaaatccgggattggggctcaggctcggacacactacgc
tgcctggcgctggccacccgggatatgcccccgaggaaggaggacatgcagctggatgac
tgcagcaagtttgcccagtatgagacggacctgaccttcgtgggctgtgtgggcatgctg
gacccaccaaggcctgaggtggctgcttgtattgcccgctgctgccaggcgggcatccgc
gtggtcatgatcacaggggacaacaaaggcacggccgtggccatctgccgccggcttggc
atcttcggggacacggaggacgtggtgggcagggcatacacaggtcgtgagtttgatgac
ctcagccctgagcagcagcgccatgcctgccagacggctcgctgctttgcccgtgtggag
cctgcgcacaagtcccgcatcgtggagtacctacagtcctttaatgaggtcaccgccatg
actggtgacggggtgaacgatgccccagccctgaagaaagcagagattggcatcgccatg
ggctcaggcacagccgtggccaagtcagcagcggagatggtgctgtcagatgacaacttt
gcctccatcgtgtctgcggtggaggagggccgagctatctacagcaacatgaagcaattc
atccgctacctcatctcctccaacgtcggcgaggtcgtctgcatcttcctcacggcaatt
ctgggcctgcccgaagccctgatccctgtgcagctgctctgggtgaacctggtgacggat
ggcttacctgccacggccctgggctttaacccaccagacctggacatcatggagaagcca
ccccggaacccccatgaggccctcatcagtggctggctcttcttccgctatctggctatt
ggcgtgtacgtgggcctggccacagtggctgctgccacctggtggttcctgtatgatgca
gagggacctcacgtcactttctaccagctgaggaacttcctgaagtgttccaaggaaaac
ccactctttgccgacgaggtggactgcaaggtcttcgagtcccgcttcccaaccaccatg
gccttgtccgtgctggtgaccattgagatgtgcaacgccctcaacagcgtctcggagaac
cagtcgctgttgcggatgccaccctggctgaacccctggctgctggcagccgtggccatg
tccatggccctgcacttcctcatcctgcttgtgccaccccttcccctcattttccaggta
accccactgagtgggcgccagtgggtggtggttctccagatatccctgcctgtcatcctg
ctcgatgaggccctcaagtacctgtcccgaaaccacatggatgaaaagggccagaagtga
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