Loxodonta africana (African savanna elephant): 100673089
Help
Entry
100673089 CDS
T04351
Symbol
CACNA1S
Name
(RefSeq) LOW QUALITY PROTEIN: voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04010
MAPK signaling pathway
lav04020
Calcium signaling pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04260
Cardiac muscle contraction
lav04261
Adrenergic signaling in cardiomyocytes
lav04270
Vascular smooth muscle contraction
lav04723
Retrograde endocannabinoid signaling
lav04725
Cholinergic synapse
lav04726
Serotonergic synapse
lav04727
GABAergic synapse
lav04911
Insulin secretion
lav04912
GnRH signaling pathway
lav04921
Oxytocin signaling pathway
lav04924
Renin secretion
lav04925
Aldosterone synthesis and secretion
lav04927
Cortisol synthesis and secretion
lav04929
GnRH secretion
lav04934
Cushing syndrome
lav04935
Growth hormone synthesis, secretion and action
lav05010
Alzheimer disease
lav05020
Prion disease
lav05022
Pathways of neurodegeneration - multiple diseases
lav05207
Chemical carcinogenesis - receptor activation
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100673089 (CACNA1S)
04020 Calcium signaling pathway
100673089 (CACNA1S)
04024 cAMP signaling pathway
100673089 (CACNA1S)
04022 cGMP-PKG signaling pathway
100673089 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100673089 (CACNA1S)
04929 GnRH secretion
100673089 (CACNA1S)
04912 GnRH signaling pathway
100673089 (CACNA1S)
04921 Oxytocin signaling pathway
100673089 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
100673089 (CACNA1S)
04924 Renin secretion
100673089 (CACNA1S)
04925 Aldosterone synthesis and secretion
100673089 (CACNA1S)
04927 Cortisol synthesis and secretion
100673089 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
100673089 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
100673089 (CACNA1S)
04270 Vascular smooth muscle contraction
100673089 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
100673089 (CACNA1S)
04725 Cholinergic synapse
100673089 (CACNA1S)
04726 Serotonergic synapse
100673089 (CACNA1S)
04723 Retrograde endocannabinoid signaling
100673089 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
100673089 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
100673089 (CACNA1S)
05020 Prion disease
100673089 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
100673089 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100673089 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
100673089 (CACNA1S)
05414 Dilated cardiomyopathy
100673089 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
100673089 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
lav04040
]
100673089 (CACNA1S)
Ion channels [BR:
lav04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
100673089 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
NPCC
Motif
Other DBs
NCBI-GeneID:
100673089
NCBI-ProteinID:
XP_023404020
LinkDB
All DBs
Position
Unknown
AA seq
1719 aa
AA seq
DB search
MEPSSPQDEGLKKKQPKKPVPENLPRPPRALFCLTLENPLRKACISIVEWKLFEMIILLT
IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTVILEQVNVIQSNTTPLGSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFQAMLPLFHIALLVLFMLIIYAIIGLELFKGKMHKTCYFIGTDIMATVENE
KPSPCSRSGLGRRCTINGSECRGSWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFLTLILLGSFFILNLVLGILSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGKLSLVEGGSDTESLYEIEGLNKIIQFVRHWRRWNRI
LRWKCHDVVKSRVFYWLVILIVALNTLSIASEHHNQPLYLTYLQDVANRVLLALFTIEML
MKMYGLGLHQYFMSIFNRFDCFVVCSGILEILLVESGAMTPLGISVLRCIRLLRLFKITK
YWTSLSNLVASLLNSVRSIASLLLLLFLFITIFALLGMQLFGGRYDFEDVEVRRSNFDNF
PQAIISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVSIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEEKKRRKMSKGLPDKSEEEKSILAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPEASSFF
IFSPTNKIRVLCHRIVNATWVTNFILLFILLSSAALAAEDPIRVKSVRNQILEYFDIVFT
SVFTVEIILKMTTFGVFLHKGSFCRNYFNILDLVVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFIFACIGVQLFKGKFFSCNDL
SKMTEEECRGYYYVYKDGDPTQMELRPRQWIHNEFHFDNVLSAMMSLFTVSTFEGWPQLL
YKAIDSNKEDMGPIYNNRVEMAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LNKNQRQCVQYALKARPLRCYIPKNPYQYKVWYFVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGGCGNVDPDESGRISSAFFRLFRVLGVIKLVGGGEGVRTLLGTF
IKSFQGALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRC
ATGEAWQEILLACSYGKLCDPESDYAPGEEYTCGTNFAYYYFISFYMLCAFLIINLFVAV
IMDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFC
PHRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWK
RTSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDTVQIQAGL
RTIEEEAAPEIHRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDNFLERTNSLP
PVMANQRPLQFAEIEMEELESPVFLEDFPQHPSTNSLARANTNNANANTACGNSNHSNSH
VFSSVHYEREFPGEREVLAAREGALGQPHRAPGQSLLCT
NT seq
5160 nt
NT seq
+upstream
nt +downstream
nt
atggagccctcctcgccccaggatgagggcctgaagaagaaacagcccaagaagcctgtt
cctgagaatctgccaaggccaccccgtgccttgttctgcctgaccctagagaaccccctg
agaaaggcctgcatcagcatcgtggaatggaaactctttgagatgatcatcttgctcacc
atctttgccaactgtgtggccctggccgtgtacttgcccatgcctgaagatgacaacaac
tctctgaacctgggcctggagaagcttgagtatttcttcctcatcgtgttctcaattgaa
gctgccatgaagatcatcgcctatggcttcctattccaccaggatgcctacctgcgcagc
ggctggaacgtgctggacttcatcattgtcttcctgggggtcttcactgtgattctggag
caggttaacgtcatccaaagcaacacaacccctttgggcagcaaaggagctggcttggac
gtcaaggccctgagagccttccgtgtgctcagacccctccggctggtgtcgggggtgccc
agcctgcaggtggtcctcaactccatcttccaggccatgctccccctgttccacattgcc
ctgcttgttctcttcatgctcatcatctatgccatcattgggttggaacttttcaagggc
aagatgcacaagacctgctacttcattggaacagatatcatggccacagtagagaatgag
aagccctcgccctgctccaggtcgggcttggggcgccggtgtaccatcaacggcagcgag
tgccggggcagctggccaggacccaaccacggcatcacccacttcgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggaggggtggaccgatgtgctttactgg
gtcaatgatgccatcgggaacgagtggccctggatctactttctcaccctcattctgctg
ggctccttcttcattctcaacctggtgctgggtattctaagtggggaattcaccaaggag
cgggagaaggccaaatccaggggaaccttccagaagctccgggagaagcagcagctggag
gaggaccttcgaggctacatgagctggattacgcagggcgaggtcatggacgtggaggat
ttaagagaagggaagctgtctttggttgaaggtggctccgacacagagagcctgtatgaa
attgagggcttgaacaaaatcatccagtttgtccgacactggaggcgctggaaccgcatc
ttacgctggaagtgccatgatgtggtgaagtccagggtcttctattggctggtgatcctg
atcgttgccctcaacaccctgtccatcgcctcagagcaccataaccagcccctatatttg
acctatttgcaagacgttgccaaccgggtgctactggctctcttcaccatcgagatgctg
atgaagatgtatgggctgggcttacaccagtacttcatgtccatcttcaaccgctttgac
tgcttcgtggtgtgcagcggcatcctagagatcctgctggtggagtcgggcgccatgaca
ccgctgggcatttctgtgcttcgctgcatccgcctcctgaggctgttcaagatcaccaag
tattggacatcactgagcaacctggtcgcatccctgctcaactccgtccgctccattgcc
tccctgctgctgctgctcttcctcttcatcaccatctttgctttgctgggcatgcagctc
tttgggggcaggtacgacttcgaggacgtggaggtgcggcgcagcaacttcgacaacttc
ccccaagccatcatcagcgtcttccaggtcctgacaggggaggactggacttcgatgatg
tacaacgggatcatggcctacggcgggccatcctaccccggcatgcttgtgtccatttat
ttcatcatccttttcgtctgtggcaactacatcttgctcaacgtcttcctggccattgct
gtggacaacctggccgaggcggagagcctgacttccgcccagaaggccaaggctgaggag
aagaaacgcaggaagatgtccaagggtctcccagacaagtcagaggaggagaagtcaatt
ttggccaagaagctggaacagaaacccaagggtgagggcatccccacaactgccaagctg
aaaatcgatgagtttgaatctaacgttaatgaggtgaaggacccttacccctcggctgac
ttcccaggggatgatgaggaagatgagcccgagatcccagtgagcccccgaccacgtccc
ctggctgagctgcagctgaaggagaaggcagtgcccattccagaagccagctccttcttc
atcttcagccccaccaataagatccgtgtcctgtgtcaccgcattgtcaacgccacctgg
gtcaccaacttcatcttgctcttcatcctgcttagcagtgctgccctggcggctgaggac
cccatccgggtgaaatctgtcaggaaccagatccttgagtattttgacatcgtgttcacc
tctgttttcactgtggagattatcctcaagatgacaaccttcggtgtcttcctgcacaag
ggctccttttgccggaactatttcaacatcctggacctggtggtagtggccgtgtccctc
atctccatgggacttgagtccagcaccatctctgtggtaaagatcctgagggtgctgagg
gtgctccgacccctccgagccatcaacagagccaaagggttgaagcacgtggtgcaatgt
gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
attttcgcctgcatcggcgtccagctcttcaagggaaagttcttcagctgcaatgactta
tccaagatgacagaagaggagtgcaggggctactactatgtgtacaaagatggggacccc
acgcagatggagctgcgtccccggcagtggatacacaacgaattccactttgacaacgtg
ctctcggccatgatgtcactcttcacagtctccaccttcgagggatggcctcagctactg
tacaaggccatagattcaaacaaggaggacatgggccccatctacaacaaccgagtggag
atggccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatcttt
gtgggcttcgttattgtcaccttccaggagcagggggagactgagtacaagaattgtgag
ctgaacaagaaccagcgccagtgtgtacagtatgccctgaaagcccgcccactgaggtgc
tacatccccaaaaacccataccagtacaaggtgtggtacttcgtcacatcctcctacttc
gaatacctgatgtttgccctcatcatgctcaacaccatctgcctgggcatgcagcactac
aatcaatcagagcagatgaatcacatctcagatatcctcaacgtggccttcaccatcatc
ttcaccttggagatgatcctcaagctcatggcattcaaggccaggggctattttggagac
ccctggaatgtgtttgacttcttgatcgtcatcggcagcatcattgacgtcatccttagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcggg
aacgttgacccagacgagagtggccgcatctccagcgccttcttccgcctgtttcgggtc
ttgggggtgatcaagctggtgggggggggagagggggtgcgcaccctgctggggaccttc
atcaagtccttccagggggccctgccttacgtggccctgctcattgttatgctcttcttc
atctacgctgtcatcggcatgcagatgttcgggaagatcgccatggtcgacgggacgcaa
ataaaccggaacaacaacttccagaccttcccacaagctgtattgcttctcttcaggtgt
gcaacaggagaggcctggcaggagatcctgctggcctgcagctacgggaagttgtgcgac
cccgagtcagactacgcccccggtgaggagtacacgtgtggcaccaacttcgcctattac
tacttcatcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtc
atcatggataactttgactacctcacacgggactggtccatcctgggccctcaccacctg
gatgaattcaaggcaatctgggcagagtacgacccggaggcaaaggggcgcatcaaacac
ctggacgtggtgaccctgctgagacggatccagccccctctgggctttgggaagttctgc
ccccaccgggtggcatgtaagcggctggtgggcatgaacatgcccctgaacagcgacgga
acggtcaccttcaacgccacgcttttcgcccttgtccgcacagcactcaagatcaagacg
gaaggtaactttgagcaggccaatgaggagctgagggccatcatcaagaagatctggaag
agaaccagcatgaagctcctggaccaagtcattcctccaataggagatgatgaggtgact
gtgggaaagttctatgccacgttccttatccaagagcacttccggaagttcatgaagcgc
caggaggagtattatgggtatcgaccaaagaaggacactgtacagatacaggctggactt
cgcaccattgaggaagaggcagcccctgagatccaccgcaccatctcaggagacctgaca
gctgaggaggagttggagagagccatggtggaggctgcgatggaggaggggatattccga
aggacaggaggcctgtttgggcaggtagacaacttcctggaaaggaccaactccctgccc
cctgtcatggccaaccagagacccctccagtttgctgagatagagatggaagaactggaa
tcacctgtcttcttggaggacttccctcaacatccaagtaccaactctcttgctcgtgcc
aataccaacaatgccaacgccaacactgcgtgcggcaacagcaaccatagcaacagccac
gtgttttccagcgttcactatgaaagggagttccctggagagagagaggtgcttgcagcc
agagaaggagccctcggacaaccccaccgggccccaggtcagtcccttctgtgcacctga
DBGET
integrated database retrieval system
