Loxodonta africana (African savanna elephant): 100674070
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Entry
100674070 CDS
T04351
Symbol
ATP1A2
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-2
KO
K01539
sodium/potassium-transporting ATPase subunit alpha [EC:
7.2.2.13
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04022
cGMP-PKG signaling pathway
lav04024
cAMP signaling pathway
lav04260
Cardiac muscle contraction
lav04261
Adrenergic signaling in cardiomyocytes
lav04820
Cytoskeleton in muscle cells
lav04911
Insulin secretion
lav04918
Thyroid hormone synthesis
lav04919
Thyroid hormone signaling pathway
lav04925
Aldosterone synthesis and secretion
lav04960
Aldosterone-regulated sodium reabsorption
lav04961
Endocrine and other factor-regulated calcium reabsorption
lav04964
Proximal tubule bicarbonate reclamation
lav04970
Salivary secretion
lav04971
Gastric acid secretion
lav04972
Pancreatic secretion
lav04973
Carbohydrate digestion and absorption
lav04974
Protein digestion and absorption
lav04976
Bile secretion
lav04978
Mineral absorption
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04024 cAMP signaling pathway
100674070 (ATP1A2)
04022 cGMP-PKG signaling pathway
100674070 (ATP1A2)
09140 Cellular Processes
09142 Cell motility
04820 Cytoskeleton in muscle cells
100674070 (ATP1A2)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
100674070 (ATP1A2)
04918 Thyroid hormone synthesis
100674070 (ATP1A2)
04919 Thyroid hormone signaling pathway
100674070 (ATP1A2)
04925 Aldosterone synthesis and secretion
100674070 (ATP1A2)
09153 Circulatory system
04260 Cardiac muscle contraction
100674070 (ATP1A2)
04261 Adrenergic signaling in cardiomyocytes
100674070 (ATP1A2)
09154 Digestive system
04970 Salivary secretion
100674070 (ATP1A2)
04971 Gastric acid secretion
100674070 (ATP1A2)
04972 Pancreatic secretion
100674070 (ATP1A2)
04976 Bile secretion
100674070 (ATP1A2)
04973 Carbohydrate digestion and absorption
100674070 (ATP1A2)
04974 Protein digestion and absorption
100674070 (ATP1A2)
04978 Mineral absorption
100674070 (ATP1A2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
100674070 (ATP1A2)
04961 Endocrine and other factor-regulated calcium reabsorption
100674070 (ATP1A2)
04964 Proximal tubule bicarbonate reclamation
100674070 (ATP1A2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
lav04147
]
100674070 (ATP1A2)
Enzymes [BR:
lav01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.13 Na+/K+-exchanging ATPase
100674070 (ATP1A2)
Exosome [BR:
lav04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
100674070 (ATP1A2)
Exosomal proteins of other body fluids (saliva and urine)
100674070 (ATP1A2)
Exosomal proteins of colorectal cancer cells
100674070 (ATP1A2)
Exosomal proteins of bladder cancer cells
100674070 (ATP1A2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
100674070
NCBI-ProteinID:
XP_003415228
LinkDB
All DBs
Position
Unknown
AA seq
1020 aa
AA seq
DB search
MGRGAGREYSPAATTAENGGGKKKQKEKELDELKKEVAMDDHKLSLDELGRKYQVDLSKG
LTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAFGIQAAME
DEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIMDSFKNMVPQQALVVREGEKIQINA
EEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNI
CFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFL
GVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLE
AVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALS
RIAGLCNRAVFKAGQENISVSKRDTAGDASESALLKCIELSCGSVKKMRERNPKVAEIPF
NSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYM
ELGGLGERVLGFCHLNLPSGKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAV
GKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVTQVNPREAKAC
VVHGSDLKDMTAEQLDEILKNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSP
ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSN
IPEITPFLMFIIVNIPLPLGTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPQTDK
LVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPSRLLGIRLDWDDRSRNDLEDSYG
QEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKTRRNSVFQQGMKNKILVFGLLEETA
LAAFLSYCPGMGVALRMYPLKVTWWFCAFPYSLLIFLYDEVRKLILRRYPGGWVEKETYY
NT seq
3063 nt
NT seq
+upstream
nt +downstream
nt
atgggccgtggggccggccgtgagtactcacctgctgccaccaccgcagagaatgggggc
ggcaagaagaagcagaaagagaaggagctggatgagctgaagaaggaggtggccatggat
gaccataagctgtccctggatgagctgggccgcaagtaccaagtggacctgtccaagggc
ctcaccaaccagcgggcccaggacatcctggctcgagatggacccaatgccctcactcca
ccccctaccacccccgagtgggtcaagttctgtcgccagctttttgggggcttctccatc
ctgctgtggatcggggccatcctctgcttcctggccttcggcatccaggctgccatggag
gatgagccatccaatgacaatctctatctgggtgtagtgctggcagctgtggtcatcgtc
accggctgcttctcctactaccaggaggccaagagctccaagatcatggattccttcaag
aacatggtgcctcagcaagccctcgtggtgcgggagggagagaagatacagatcaatgca
gaggaggtagtggtgggagacctggtagaagtgaagggtggagaccgcgtccctgctgac
ctccgtatcatctcttctcacggatgtaaggtggataactcatccctcacaggcgagtca
gagccccagacccgctccccggagttcacgcatgagaaccctctggagacccgcaatatc
tgtttcttctctactaactgtgttgaaggcactgccaggggcatcgtgattgccacaggt
gaccggacagtgatgggtcgcatagccactctggcctcaggcctagaggttgggcggacg
cctatagctatggagatcgaacacttcatccagctgatcacaggggtggccgtgttcctg
ggagtctccttcttcgtactctccctcatcctgggctacagttggctggaagcagtcatc
ttccttatcggcatcattgtggccaatgtgcctgaagggctgctggccactgtcactgtg
tgtctgaccctgacagccaagcgcatggcgcgaaagaactgcctggtgaagaaccttgag
gcggtggagacgctgggctccacctccaccatctgctctgacaagacaggcacccttacc
cagaatcgtatgactgtcgcccacatgtggtttgataaccagatccatgaggctgacacc
acagaagaccagtctggggccacttttgacaaacgatcccccacatggacagctctgtct
cggattgccggtctttgcaaccgtgctgtcttcaaggccggacaggagaacatctctgta
tctaagcgggacacagctggtgatgcctctgagtcagctctgctcaagtgcattgagctg
tcctgtggctcagtgaagaagatgagggagaggaaccccaaggtggcagagattcctttc
aactccaccaacaaataccagctgtccatccatgaaagagaagacagcccccagagccat
gtgctcgtgatgaagggggccccagagcgcatcctggaccggtgctccactatcctggtg
cagggcaaggagatcccactggacaaggaaatgcaagacgccttccaaaatgcctacatg
gagctgggaggattgggggagcgtgtcctggggttctgtcacctgaatctgccatctgga
aagtttcctcggggcttcaaattcgacacagatgagctgaactttcccacggagaagctc
tgctttgtggggctcatgtctatgattgaccctccccgggctgcagtgccggatgctgtg
ggcaaatgccggagcgcaggcatcaaggtgatcatggtgactggggatcatcctatcaca
gccaaggccattgccaaaggcgtgggcattatatccgagggcaacgagactgtggaagac
attgcagcccggctcaacattcctgtgactcaagtcaaccccagagaagccaaggcgtgt
gtggtgcacggctctgacctgaaggacatgactgcagagcagctcgacgagatcctcaag
aaccacacggagattgtgttcgctcggacctcccctcagcagaagctcatcatcgtggag
ggatgtcagaggcagggtgccatcgtggcagtgacgggtgatggagtgaatgattcccct
gcgctgaagaaggctgacattggcattgccatgggcatctctggctctgatgtctctaag
caggcggccgacatgatcctgctggacgacaactttgcctccattgtcacaggcgtggag
gagggccgcctgatctttgacaacctgaagaaatccattgcctacaccctgaccagcaac
attcctgagatcacccccttcctgatgttcatcattgtcaacatccccctccctctgggc
accgtgaccatcctctgcattgacctaggcacagacatggtccccgccatctccttggcc
tatgaggcagccgagagtgacatcatgaagcggcaacccagaaacccccagacagacaaa
ctggtgaacgagaggctcatcagcatggcctatggacagattggaatgatccaggccctg
ggtggcttcttcacctactttgtgatcctggccgagaacggtttcctaccatcacggctg
ctgggaatccgcctagactgggatgaccggtccaggaatgacctggaggacagctatgga
caggagtggacctatgagcagcggaaggtggtggagttcacgtgccacacggccttcttt
gccagcatcgtggtcgtacagtgggctgacctcatcatctgcaagacccgccgcaactca
gtcttccagcagggcatgaagaacaagattctggtatttgggctcctggaggagacagcg
ctggctgcttttctgtcttactgcccaggcatgggtgtagccctccgcatgtacccgctc
aaggtcacttggtggttctgtgccttcccttacagtctcctcatcttcctctatgacgag
gtccggaagctcatcttacggcgatatcctggtggctgggtggagaaggagacatactac
tga
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