Loxodonta africana (African savanna elephant): 100676104
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Entry
100676104 CDS
T04351
Symbol
SHMT2
Name
(RefSeq) serine hydroxymethyltransferase, mitochondrial
KO
K00600
glycine hydroxymethyltransferase [EC:
2.1.2.1
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00260
Glycine, serine and threonine metabolism
lav00630
Glyoxylate and dicarboxylate metabolism
lav00670
One carbon pool by folate
lav01100
Metabolic pathways
lav01200
Carbon metabolism
lav01230
Biosynthesis of amino acids
lav01240
Biosynthesis of cofactors
lav01523
Antifolate resistance
lav04981
Folate transport and metabolism
Module
lav_M00141
C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00630 Glyoxylate and dicarboxylate metabolism
100676104 (SHMT2)
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
100676104 (SHMT2)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
100676104 (SHMT2)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
100676104 (SHMT2)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
100676104 (SHMT2)
Enzymes [BR:
lav01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.1 glycine hydroxymethyltransferase
100676104 (SHMT2)
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SSDB
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Paralog
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Motif
Pfam:
SHMT
Motif
Other DBs
NCBI-GeneID:
100676104
NCBI-ProteinID:
XP_003405192
UniProt:
G3T7N9
LinkDB
All DBs
Position
Unknown
AA seq
504 aa
AA seq
DB search
MVPFSFLWAARPLQRCSQLVRMAIQAQYSKTAQTQSGEAARGWTGQESLSDSDPEMWKLL
QREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQ
RRALEAFDLDPAQWGVNVQPYSGSPANLAAYTALLQPHDRIMGLDLPDGGHLTHGYMSDV
KRISATSIFFESMPYKLNPKTGLIDYDQLALTARLFRPRLIIAGTSAYARLIDYARMKEV
CDEVKAHLLADMAHISGLVAAKVIPSPFEYADIVTTTTHKTLRGARSGLIFYRKGVQAVD
PKSGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLRNAQA
MADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAIT
PGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLSDPETGQ
QLADLRQRVEQFARAFPMPGFDEH
NT seq
1515 nt
NT seq
+upstream
nt +downstream
nt
atggtgcctttctctttcctctgggctgcccggcctctacagagatgcagtcagctggtc
aggatggccatacaggcccaatacagcaagacagcccagacccagtctggggaagcagcc
cggggctggacaggccaagagagcctgtccgacagtgaccctgagatgtggaagctgctg
cagagggagaaggacaggcagtgtcgtggcctggagctcattgcctcagagaacttctgc
agccgagctgcgctggaggccctggggtcctgtctgaacaacaagtactcggagggttat
cctggcaagagatattacggaggagcagaagtagtggatgagatcgagctgctgtgtcag
cgccgggctttggaggcctttgatctggatcctgcacagtggggagtcaatgttcagccc
tattcggggtctccagccaatctggccgcctacacagcccttctgcagccccatgaccga
atcatggggctggacctgcctgatgggggccatctcacccatggctacatgtccgatgtc
aagcggatctcagctacatccattttctttgagtccatgccctataagctgaatcccaaa
actggcctcattgactatgaccagttggcactgactgcccggctcttccgaccacggctt
attattgctggtaccagtgcctatgctcgcctcattgactatgcccgaatgaaagaggtg
tgtgatgaggtcaaagcacacctactggcagatatggcccacatcagcggcctggtggct
gccaaggtgatcccctcacctttcgagtatgcagatattgtcaccaccaccactcacaag
acccttcgaggggccaggtcaggactcatcttctaccggaaaggggttcaggctgtggac
cccaaatctggccgtgagatcccttacacatttgaagaccgaatcaactttgccgtgttc
ccgtcacttcagggcggcccccataaccatgccattgctgcagtagctgtggccctaaag
caggcttgcacccccatgttccgagagtactccctgcaggttctgagaaacgctcaggcc
atggctgacgccctgctagagcgaggctactcactggtgtctggtggcactgacaaccac
ctggtgctggtagacctacggcccaaaggcctggatggagctcgggctgagcgggtgttg
gagcttgtatcaatcactgccaacaagaacacctgtcctggagaccgaagtgctatcaca
cctgggggcctgcggcttggagccccagccttgacctctcgacagttccgtgaagatgac
tttcggagagttgtggactttatagatgaaggtgtcaatatcggcttggaggtgaagagt
aagactgccaagctccaggatttcaaatccttcctgctcagcgacccagaaacagggcag
cagctggctgacctcaggcaacgggtagagcagtttgccagagccttccccatgcctggt
tttgatgagcactga
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