Loxodonta africana (African savanna elephant): 100677152
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Entry
100677152 CDS
T04351
Symbol
ABL1
Name
(RefSeq) tyrosine-protein kinase ABL1 isoform X1
KO
K06619
abelson tyrosine-protein kinase 1 [EC:
2.7.10.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04012
ErbB signaling pathway
lav04014
Ras signaling pathway
lav04110
Cell cycle
lav04360
Axon guidance
lav04722
Neurotrophin signaling pathway
lav05200
Pathways in cancer
lav05206
MicroRNAs in cancer
lav05208
Chemical carcinogenesis - reactive oxygen species
lav05220
Chronic myeloid leukemia
lav05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
100677152 (ABL1)
04014 Ras signaling pathway
100677152 (ABL1)
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
100677152 (ABL1)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
100677152 (ABL1)
09158 Development and regeneration
04360 Axon guidance
100677152 (ABL1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100677152 (ABL1)
05206 MicroRNAs in cancer
100677152 (ABL1)
05208 Chemical carcinogenesis - reactive oxygen species
100677152 (ABL1)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
100677152 (ABL1)
09166 Cardiovascular disease
05416 Viral myocarditis
100677152 (ABL1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
lav01001
]
100677152 (ABL1)
Enzymes [BR:
lav01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
100677152 (ABL1)
Protein kinases [BR:
lav01001
]
Non-receptor tyrosine kinases
ABL family
100677152 (ABL1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
F_actin_bind
SH2
SH3_1
SH3_2
SH3_9
Haspin_kinase
Kinase-like
SH3_6
Motif
Other DBs
NCBI-GeneID:
100677152
NCBI-ProteinID:
XP_003407604
UniProt:
G3SZ92
LinkDB
All DBs
Position
Unknown
AA seq
1142 aa
AA seq
DB search
MGQQPGKVLGDQRRPSLPALHFIKGAGKKESSRHGGPHCNVFVEHEALQRPVASDFEPQG
LSEAARWNSKENLLAGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCE
AQTKNGQGWVPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQR
SISLRYEGRVYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVADGLITTLHYPAPKRN
KPTVYGVSPNYDKWEMERTDITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLKEDTMEVE
EFLKEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRECNRQEVNAVVLL
YMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKF
PIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERP
EGCPEKVYELMRACWQWNPSDRPSFAEIHQAFETMFQESSISDEVEKELGKKGVRGVAST
LLQAPELPTKTRTSRRAAEHKDSADVPETPHSKGQGESDPLDHEPTVSPLLPRKERGPQD
ASLNEDERLLPKDKKTNLFSALIKKKKKTAPTPPKRSSSFREMDGQPERKGGGEEEGQEI
SNGALAVMPSDTTEPSKSPKPSNGTSVPNGAFRSPHLWKKSNMLTSNRLAASEEESGSSS
SKRFLRSCSASCVPHGAKDTEWRSVTLPRDLQSTGRQFDSSTFGGHKSEKPALPRKRASE
NRSDQVTRGTVTPPPRLVKKNEETADEVFKDTTESSPGSSPPSLTPKLVRRQVMMAPSSG
HPQKEEAGKSSALGTSVTAEPVPPTSRAGSGASGGGTKAPTEESRVRRHKQPSESPGRDK
GKVSRLKPAPPPPPPASVGKAGKSSQSPSHEAAGEAGAGAKAKSMTLGVDAVSSEATKPN
QLGEGIKKPVLPSIPKPQSSTKPSGTPTSPAPASSSLPSASSSLGGDQQSSTAFIPLIST
RVSLRKTRQLPERIASGTITKGVVLDSTNALCLTISKNSEQMASHSAVLEAGKNLYTFCV
SYVDSIQQMRNKFAFREAINKLENNLRELQICPATAGSGPAATQDFSKLLSSVKEISDIV
QR
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atggggcagcagcctggaaaagttcttggggaccaacgaaggccaagtttgcctgccctg
cactttatcaaaggagcagggaagaaggaatcatcgaggcatgggggtccacactgcaat
gtttttgtggaacatgaagcccttcagaggccggtagcatcagattttgagccccaaggt
ctgagcgaagcagctcgttggaactccaaggaaaaccttcttgctggtcccagtgaaaat
gaccccaaccttttcgttgcactgtatgattttgtggccagtggggataatactctaagc
ataactaaaggtgaaaagctccgggtcttaggctacaatcacaatggtgaatggtgtgaa
gcccaaaccaaaaatggccaagggtgggttccaagcaactacatcacgcctgtcaacagt
ctggagaaacattcctggtaccatgggcctgtgtcacgcaatgctgctgaatacctactg
agcagcggaataaatggcagcttcttggtgcgagagagcgagagcagtcctggccagagg
tccatctcgctgagatatgaaggaagggtgtaccactacaggatcaacactgcatctgat
ggcaagctctacgtctcctcagagagccgctttaatactttggccgagttggttcatcac
cattcaacagtggcagacgggctgattaccactctccattatccagcccccaagcgcaac
aagcccactgtctatggtgtgtcccccaactatgacaagtgggagatggaacgcacagac
atcaccatgaagcacaaactgggaggaggccagtatggggaggtgtatgaaggagtgtgg
aagaaatatagcctgacggtggcagtaaagaccttgaaggaggataccatggaggtggaa
gagttcttgaaagaagctgcagtaatgaaagagatcaaacaccctaatctagtgcagtta
ctcggcgtctgtacccgggagcccccgttctacataatcaccgagttcatgacctatggg
aacctgttggattacctgagggagtgcaatcggcaggaggtgaatgctgtggtgctactg
tatatggccactcagatctcgtcagccatggagtacctggagaagaaaaacttcatccac
agggatcttgctgcccgaaactgcctggtaggggaaaaccacttggtgaaggtggctgat
tttggcctgagcaggttaatgacaggtgatacctacacagcccacgccggagccaagttc
ccgatcaaatggaccgccccagaaagcctggcctacaacaagttttccattaagtctgat
gtctgggcatttggagtattgctttgggaaatagctacctatggcatgtcaccttaccca
ggaattgacctgtcccaggtgtatgagctactggaaaaagactatcgcatggaacgcccg
gaaggctgcccagagaaagtctatgaactcatgcgagcatgttggcagtggaatccctct
gaccggccctcctttgctgaaatccaccaagcctttgaaacaatgtttcaggaatccagc
atatcggatgaagtggaaaaggaactggggaaaaaaggcgtacgaggtgttgcaagtact
ttgctgcaggccccagagctgcccaccaagacgagaacctccaggagagctgcagagcac
aaagactcggctgacgtgcctgagacgccccactccaagggccagggagagagtgatcct
ctggaccatgagcccactgtgtccccattgctccctcggaaagagcgaggtccccaggat
gccagcctaaatgaagatgagcgccttctccccaaagacaaaaagaccaacttgttcagc
gccttaatcaaaaagaagaagaaaacagcccccacccctcccaaacgcagcagctccttc
cgtgagatggacggccagccagagcgcaaggggggcggtgaggaagagggccaagaaatc
agcaacggggcgctggctgtcatgccctcagacacaaccgagccaagcaagtccccaaag
cccagcaatgggaccagcgtccccaatggagccttccggtctcctcatctgtggaaaaag
tccaacatgctgaccagcaaccgattagcagccagtgaagaggagagtggcagcagctcc
agcaagcgcttcctaagatcctgctctgcctcctgtgtgccccacggagccaaggacaca
gagtggaggtcagtcacactgcctcgggatttgcagtccacaggaagacagtttgactcg
tccacatttggagggcacaaaagtgagaagccagccttgcctcggaaacgggcaagtgag
aacaggtctgaccaggtgaccaggggcacagtgacacccccacccagactggtgaagaag
aacgaggaaacagctgatgaggtcttcaaagataccacagagtccagcccaggctccagt
cctcccagtttgactccgaaacttgttcgcaggcaagtcatgatggctccttcctctggc
catccccagaaggaagaggccgggaaatccagtgccttagggacctctgtcacagctgag
ccagttccccccaccagcagagcagggtcaggtgcatctggaggtggcaccaaggcccct
actgaggagtccagagtaaggaggcacaagcagccctccgagtctccggggagagacaag
gggaaagtgtccaggctcaaacctgccccaccgcccccacccccagcctctgttgggaaa
gctggaaagtcctctcagagcccgagccatgaagcagctggggaggcaggagccggtgct
aaagcaaaatccatgaccctgggtgtggatgctgtgagcagtgaggctaccaagccaaac
cagctaggagagggcatcaaaaagcctgtgctcccttccataccaaagccacagtcatct
accaagccatcggggaccccaaccagcccagcccctgcttcctcatcattgccgtcagca
tcctcatccctgggaggggaccagcagtcctccactgccttcatccctctcatctctaca
cgtgtctctcttcggaaaacccggcagcttccggagcggattgccagtggcaccattacc
aagggtgtggtcctggacagcaccaatgccttgtgcctcaccatctccaagaactctgaa
cagatggccagccacagtgcagtgctggaagctggcaaaaacctctacacgttctgtgtg
agctacgtggattctatccagcaaatgaggaacaaattcgccttccgtgaggccatcaac
aaactggagaacaatctccgggagcttcagatctgcccggcgactgcggggagtggccca
gccgccactcaggactttagcaaactcctcagctcagtgaaagaaatcagtgacatcgta
cagaggtag
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