Loxodonta africana (African savanna elephant): 100677404
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Entry
100677404 CDS
T04351
Symbol
LAMA2
Name
(RefSeq) laminin subunit alpha-2
KO
K05637
laminin, alpha 1/2
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04151
PI3K-Akt signaling pathway
lav04510
Focal adhesion
lav04512
ECM-receptor interaction
lav04820
Cytoskeleton in muscle cells
lav05145
Toxoplasmosis
lav05146
Amoebiasis
lav05165
Human papillomavirus infection
lav05200
Pathways in cancer
lav05222
Small cell lung cancer
lav05410
Hypertrophic cardiomyopathy
lav05412
Arrhythmogenic right ventricular cardiomyopathy
lav05414
Dilated cardiomyopathy
lav05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
100677404 (LAMA2)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
100677404 (LAMA2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100677404 (LAMA2)
09142 Cell motility
04820 Cytoskeleton in muscle cells
100677404 (LAMA2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100677404 (LAMA2)
09162 Cancer: specific types
05222 Small cell lung cancer
100677404 (LAMA2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
100677404 (LAMA2)
09174 Infectious disease: parasitic
05146 Amoebiasis
100677404 (LAMA2)
05145 Toxoplasmosis
100677404 (LAMA2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
100677404 (LAMA2)
05412 Arrhythmogenic right ventricular cardiomyopathy
100677404 (LAMA2)
05414 Dilated cardiomyopathy
100677404 (LAMA2)
05416 Viral myocarditis
100677404 (LAMA2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Laminin_G_1
Laminin_G_2
Laminin_EGF
Laminin_B
Laminin_I
Laminin_N
Laminin_II
Laminin_G_3
LXG
DUF948
DUF6594
Motif
Other DBs
NCBI-GeneID:
100677404
NCBI-ProteinID:
XP_023413930
LinkDB
All DBs
Position
Unknown
AA seq
3097 aa
AA seq
DB search
MPLCSGPHVFTCLSFLGLFPAVLNLASNAVITTNATCGEKGPEMYCKLVEHVPGQPVRNP
QCRICNQNSSNPYQRHPITNAIDGKNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIV
KAANSPRPGNWILERSLDDVEYKPWQYHAVTDSECLTLYNIHPRTGPPSYAKDDEVICTS
FYSKIHPLENGEIHISLINGRPSADDPSPELLEFTSARYIRLRFQRVRTLNADLMMFAHK
DPREIDPIVTRRYYYSIKDISVGGMCICYGHARACPLDPETNKSRCECEHNTCGDSCDQC
CPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYLGGGVCINC
TQNTAGINCETCIDGFFRPKGVSPKYPRPCQPCHCDPTGSLNEVCVKDEKHARRGLAPGS
CHCKSGFGGVSCDRCARGYTGYPSCQSCNCSGIGSRNEDPCFGPCNCKENVEGGDCSSCK
PGFFNLQEDNHKGCDECFCSGVSNRCQSSYWTYSNIQDMSGWYLTDISGRIRVAPQQDDF
DAPQQTSINNAEARLRLPQSYYWSAPAPYLGNKLTAAGGQLTFTISYDLEEEEEDTERAL
QLMIILEGNGLRISTAQDEVYLLPSEEHINVLSLKEELFTIHGTNVPVSRKEFMTVLANL
KRLLIQTTYSLGMDAIFRLSSVILESAVPYPTDGSIAAAVEVCQCPPGYSGSSCESCWPR
HRRVNGTIFGGICEPCQCFGHAESCDDVTAECVNCKDHTSGPYCNECLPGFYGDPTKGTS
EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDECPVGYTGPRCERCAEGYFGQPSIPGGS
CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCN
VNGSFSEVCHARTGQCECRPNVQGWKCNECKPETFGLQSARGCVPCNCNSFGSKSFDCEE
SGQCWCQPGVTGKKCDHCAHGYFKFQEGGCTACDCAHLGNNCDPKTGRCICPPNTVGEKC
SKCVPNTWGYSIISGCKVCNCSLVGSLDIQCNINTGQCKCHPKFSGAKCTECKLGHWNYP
HCDLCDCFLPGTDGTTCDTETKKCSCSDQTGQCTCKMNVEGVHCDRCRPGKFGLDAKNPL
GCSSCYCFSATSQCSEAKGLIRTRVTLNPEQTILPLVDEALQHTTTKGIAFQHPEIVAHM
DLVKQDLHLEPFYWKLPEQFEGKKLMAYGGKLKYAIYFEAREETGFSTYNPQVIIRGGTP
AHARIIVRHMAAPLIGQLTRHEIEMTEKEWKYYGDDPRISRTVTREDFLDVLYDIHYILI
KATYGNIMRQSRISEISMEVAEKGRVTAVTPRAHLIEKCDCPLGYSGLSCETCLPGFYRL
PSELGGRTPGPTLGTCVPCQCNGHSSLCDPETSKCQNCQHHTGGDFCERCALGYYGIVKG
SPNDCRQCACPLISSSNNFSPTCVMEGLDDYRCSACPRGYEGQYCERCAPGYTGSPRSPG
GSCQECECDPHGSLPVPCDPVTGLCTCRPGATGQKCDGCKHWHAREGMECVFCGDECTGL
LLGDLARLEQMAMSINLTGPLPAPYKMLYSLENTTQELKHLLSPQRAPERLIQLAEGNLN
TLVTEMNELLTRATKVTADGEQTGQDAERTNTRAKSLGEFIKELVQDAEAVNDKAAKLND
TLGAQDKAFERNLQGLQKEIDQMMTELRRKNLDTQKEAAEDELVAAEALLKKVKKLFGES
RGKNEEMEKDLREKLADYNNKVDDAWDLLREATDKIREANRLSTANQKNMTALEKMKEAL
ESGKRQTENTLKEGNDILDEANRLADGINSVIEYVEDIQTKLPPMSEELKDKIDGLSREI
KDRNLAEKVSQAENHAAELNDSSTVLDGILDEAKNISFNATAAFKAYSNIKDYIDEAEKV
AEEAKGLANEATELATGPQGLLKEGAKASLQKSFRILNEAKKLANNVKENDDHLNGLTNR
LENASVRNGELLKALNDTLGKLSAIPNDTAVKLQAVKDKARQANDTAKDVLAQIKDLHQN
LDGLKKNYNKLADSIAKTNAVIKDPSKNKIIADADATVKNLEQEADRLIDKLKPIKELED
NLKKNISEIKELINQARKQANSIKVSVSSGGDCIRTYKPEIKKGSYNHIVINVKTAVADN
LLFYLGSAKFIDFLAIEMRKGKVSFLWDVGSGVGRVEYPDLTIDDSYWYRIEASRTGRNG
TISVRALDGPKASIVPSTYSSVSPPGYTILDVDANAMLFVGGLTGKLKKADAVRVITFTG
CMGETYFDSKPIGLWNFREKEGDCKGCTVSPQVEDSEGTIQFDGEGYALVSRPIRWYPNI
STVMFKFRTFSSSALLMYLATRDLKDFMSVELTDGRIKVSYDLGSGMASVASNQNHNDGK
WKSFTLSRIQKQANISIVDIDTNQEENIATSSSGNNFGLDLKADDKIYFGGLPTLRNLRP
EVNLRKYSGCLKDIEISRTPYNILSSPDYVGVTKGCSLENVYTVSFPKPGFVELAPVPIN
VGTEINLSFSTKNESGVILLGSGGTPAPPRRKRRQTGQAYYAIFLNKGRLEVHLSTGART
MRKIVIKPEPSLFHDGREHSVHVERTRGIFTVQVDEDRRHVQNMTVEQAIEVKKLFVGGA
PLEFQPSPLRNIPPFEGCIWNLVINSVPMDFAQPVSFKNADIGRCADQKPPEDEDGAVPA
EILILPEPVPTPAFPTPTPVLAHGPCAVDSEPALLLGSKQFGLSKNSHIAIAFDDTKVKN
RLTIEFEVRTEAESGLLFYMARINHADFATVQLRNGLPYFSYDLGSGDTKTMIPTKINDG
QWHKIKIMRIKQEGILYVDDASNRTISPKKADILDVVGMLYVGGLPINYTTRRIGPVTYS
IEGCIRNLQMAEAPADLEKPTSSFHVGTCFADAQKGTYFDGTGFATAVGGFKVGLDLLVE
FEFRTTRTTGVLLGISSQKMDGMGIEMIDEKLMFHVDNGAGRFTAVYDAGIPGRLCDGQW
HKVTANKIKHRIELTVDGNQVEAQSPNPASTSADTNDPVFVGGFPDGLNQFGLTTNIRFR
GCIRSLRLTKGTGKPLEVNFAKALELRGVQPVSCPAN
NT seq
9294 nt
NT seq
+upstream
nt +downstream
nt
atgccactttgttctggaccacacgtattcacttgtctgtcttttttaggtttatttcct
gctgtgctgaatcttgcttctaatgctgtcatcaccaccaatgcaacatgcggagaaaaa
ggacctgaaatgtactgcaaattggtagaacacgtccctggacagcctgtgaggaaccct
caatgtcgaatctgcaatcaaaacagcagcaatccctaccagagacacccgattacaaat
gcgattgatggaaagaacacttggtggcagagccccagtattaagaatggaattgaatac
cattatgtgacaattacactggatttacagcaggtgttccagattgcatatgtgattgtg
aaagcggctaactcccctcggcctggaaactggatcttggaacgctctcttgatgacgtt
gaatacaagccatggcagtatcatgctgtgactgactcggagtgcctaaccctctacaat
atacatccccgcacagggccaccgtcatatgccaaggacgatgaggtcatctgcacttcg
ttttattccaagatacaccctttagaaaatggagagattcacatctctttgatcaatgga
agaccaagtgctgatgacccttctcctgaactgctggaatttacctcagctcgctatatt
cgcctgagatttcagagggtccgcaccttgaatgctgatttgatgatgtttgcccacaaa
gacccaagagaaattgaccccattgtcacaagaagatattactactccatcaaggatatt
tcggtcggagggatgtgcatctgctatggtcatgccagggcttgtccgcttgatccagag
acaaataaatcccgttgtgaatgtgagcataatacatgtggtgatagctgtgatcagtgc
tgtccaggattccatcaaaaaccttggagagctgggacttttctaactaaaactgaatgt
gaagcatgcaattgccatgggaaagctgaagaatgctattatgatgaaaatgttgccaga
agaaatctgagtttaaatatacgtggaaagtaccttggagggggtgtgtgcattaattgt
acccaaaacactgccggcataaactgtgagacatgtattgatggcttcttcagacccaaa
ggggtgtctccaaagtatccaagaccatgtcagccatgtcattgtgatccaactggttcc
ttaaatgaagtctgtgtcaaggatgagaaacatgctcgacgaggtctggcacctggatcc
tgtcattgcaaaagtggctttggaggggtaagctgtgatcgatgtgccaggggttacact
ggctaccccagttgccaatcctgcaactgcagtggcataggaagcagaaatgaggaccct
tgttttggaccctgtaactgcaaggagaacgttgaaggtggagactgcagtagttgcaaa
cctggcttcttcaatttgcaagaggataaccataaaggctgtgatgagtgtttctgttca
ggggtttcaaacagatgtcagagttcctactggacctacagcaatatacaagacatgagt
ggctggtacctgactgacatctctggccgcatccgagtggctccgcagcaggacgacttt
gatgcaccccaacagaccagtatcaataatgcagaggccagactaaggttgccacagagc
tactactggagtgccccagctccctatctgggaaacaaactcacagcagctggaggacaa
ttgacattcaccatatcatatgacctagaagaagaggaagaagatacagaacgtgcactc
cagcttatgattatcttggagggaaatggcttgcgcatcagcacagcccaagatgaggtg
tacctgctaccatctgaagaacatattaatgttctgtcacttaaagaagaattatttacc
atacatggcacaaatgtcccagtcagcagaaaagaatttatgacagtgcttgcgaattta
aagagactcctcatacaaaccacatacagccttgggatggatgccatcttcaggttgagt
tctgttatccttgaatccgctgttccctatcctactgacggaagcattgcagcagctgtg
gaagtttgtcagtgtccaccagggtatagtggttcctcttgtgaatcttgttggcctcgg
catagacgagttaacggcacgatttttggtggcatctgcgagccatgtcaatgctttggt
catgcagagtcctgtgacgacgtcactgcagaatgcgtgaattgtaaagaccacacaagt
ggcccatactgcaatgaatgtcttcctggtttctatggtgatcctactaaaggtacctct
gaagactgtcaaccctgcgcctgtcctctcaatatcccatctaataactttagcccgacg
tgccatttagaccggagtcttggattgatctgtgatgaatgccctgtcgggtacacaggc
ccacgctgtgaaaggtgtgcagaaggctattttggtcaaccatctatacctggaggatca
tgtcagccatgccaatgcaatgacaaccttgacttctccatccctggcagctgtgacagc
ttgtctggctcctgtctgatatgtaaaccaggtacaacaggccgctattgcgagctctgt
gccgatggatattttggagacgcggttgatgcaaagaactgtcagccctgtcgctgtaac
gtcaacggctccttctccgaggtttgccacgctcggacagggcagtgtgaatgcagaccc
aatgtgcagggatggaagtgcaatgagtgcaagcctgaaactttcggcctacagtcagca
agggggtgtgtgccctgcaactgtaattccttcgggtctaaatcttttgattgtgaagag
agtggacaatgctggtgccagcctggagtaacaggaaagaaatgtgaccattgtgcccat
ggctatttcaaattccaagaaggaggatgcacagcttgtgactgtgctcatctgggtaat
aattgtgaccccaagactggtcgatgcatttgccctcccaatactgttggagagaaatgt
tctaaatgcgtacccaacacctggggctacagcattatcagtggatgtaaggtttgcaat
tgcagtttggtgggatctcttgatatccagtgcaatataaacacaggccaatgcaaatgt
catccaaaattctccggtgcaaaatgtacagagtgcaagctaggtcactggaattaccct
cattgcgacctctgtgactgcttcctgcctgggactgacggcacgacctgtgacacagag
actaagaaatgttcatgtagcgatcagactggccagtgtacatgcaagatgaacgtggaa
ggtgtccactgtgacaggtgccggcctggcaaatttggacttgatgccaagaacccactt
ggttgcagcagctgctattgcttcagtgctacttctcagtgctctgaagcaaaaggactg
atccgtacgcgggtaacactgaaccctgagcagaccattctgccacttgtggatgaggca
ctgcagcacacaactaccaagggcattgcttttcagcacccggagatcgttgcacacatg
gacctggtgaaacaagatctccatttagaaccattttattggaaacttccagaacaattt
gaaggaaagaagttgatggcctatggtggcaagctcaagtatgcaatctattttgaggct
cgggaagaaacaggtttctctacttataatcctcaagttatcattcgaggtgggactcct
gctcatgctagaattattgtcagacacatggctgctcctctaattggccaattgacaagg
catgaaattgaaatgacagagaaagaatggaaatattatggtgatgatcctcgaatcagt
aggactgtgacccgagaagacttcttggatgtactgtacgatattcattatattcttatc
aaggctacttatgggaatatcatgcgacaaagcaggatttctgaaatctcaatggaggta
gctgaaaaaggacgtgtgacagcagtgactcctcgagctcacttgatagaaaaatgtgat
tgtcccctgggctattctggcttgtcctgtgagacatgcttgccaggattttatcgactg
ccttctgaactgggtggccgcacccctggaccaaccctgggcacctgtgttccatgtcag
tgtaatggacacagcagcttatgtgaccctgaaacgtccaaatgccagaattgtcagcat
cacactggtggtgacttctgtgaacgttgtgccctcggatactacggaattgtcaaagga
tcaccaaatgactgtcggcaatgtgcttgccctctgatttcttccagcaacaatttcagt
cctacttgtgtcatggaaggtcttgatgattaccgctgcagtgcttgtccacggggatat
gaaggccagtactgtgaaaggtgcgcccctggctatactggaagtccaagaagcccagga
ggttcctgccaagaatgtgagtgtgacccccatggctcacttcctgtcccttgtgaccca
gtcacagggctctgcacgtgccgacctggagccacagggcagaagtgtgacggctgcaag
cactggcatgcgagagagggcatggagtgtgttttttgtggagatgagtgcacgggcctt
cttctcggtgacttggctcgcctggaacagatggccatgagcatcaacctcactggtccg
ctgcctgctccctataaaatgctgtacagtctcgaaaacacgactcaagaactaaagcac
ttgctctcacctcaacgggccccagaaagactcattcagttggcagagggcaatctgaat
acactcgtgacagaaatgaatgagcttctgaccagggctaccaaagtgacagcagatggc
gagcaaactggacaggatgctgagaggaccaacacgagagcaaagtctttaggagaattc
attaaggagctcgtccaggatgcagaagctgtaaatgacaaagctgcaaaactaaatgac
actctgggagctcaagacaaggcctttgagagaaatttgcaaggacttcagaaagagatt
gatcagatgatgacagaattgaggaggaaaaatctagatacacaaaaggaagccgctgaa
gatgagttggtagctgcagaagcccttctgaagaaagtgaagaagctgtttggagagtct
cgggggaaaaatgaagaaatggagaaggatctccgtgagaaactggctgactacaacaac
aaagtggatgatgcttgggacctattgagagaagccacagataaaatcagagaagctaat
cgcttgtctacagcaaaccagaaaaacatgacagctttggagaaaatgaaggaggctctt
gaaagtggcaaacggcaaactgagaacactttaaaagaaggcaatgacatacttgatgaa
gccaaccgtcttgcagatggaatcaactcagtgatagaatatgttgaagacattcaaact
aaattgccaccaatgtctgaagagcttaaagataaaatagatggcctctcccgtgaaatc
aaagacaggaatcttgctgagaaggtgtcccaggccgaaaaccatgctgctgagttgaat
gactcctctactgtccttgatggaatccttgatgaagctaaaaacatttccttcaatgcc
actgcggccttcaaagcttacagcaatattaaggactatattgatgaagcagagaaagtt
gccgaagaagccaaaggtcttgcaaatgaagctacagaactggcaacaggtcctcagggc
ttattgaaagaaggtgccaaagcctctcttcagaaaagcttcaggattcttaatgaagcc
aagaagttagcaaataatgtaaaagaaaatgatgatcacctgaatggcttgacaaacagg
ttagaaaatgccagtgttagaaatggggagctcctgaaagccttgaatgacactttggga
aagttatcagccattccaaatgatacagccgtgaaactgcaagctgttaaggacaaagca
agacaagccaatgacacagcaaaagatgtactggcacagattaaagacctccaccagaac
ctcgatggcctgaagaaaaattacaataaactagcggacagcatagccaaaacaaatgct
gtgataaaagatccttctaagaacaaaatcattgcagatgcagacgccactgtgaaaaat
ttagaacaagaggctgatcgactaatagataaactcaaacctatcaaggaacttgaggat
aacctgaagaaaaacatttctgagataaaagaactgataaaccaagctaggaaacaagcc
aattctatcaaagtatctgtgtcttctggaggtgactgcattcgaacatacaaaccagaa
atcaagaaaggaagctacaatcatatcgttatcaatgtcaagacagctgttgctgacaat
cttcttttttatcttggaagtgccaaatttattgactttctggctatagaaatgcgtaaa
ggcaaagtaagcttcctttgggatgttggatctggagttggacgtgtagaatatccggat
ttgactattgatgactcatattggtaccgtattgaagcatcaagaactgggagaaatgga
acaatttcggtgagagccctggatggacccaaagccagcattgtgcccagtacatacagt
tcagtctcaccaccagggtatactatcctagatgtggatgcaaacgcaatgctgtttgtt
ggtggcttgactgggaagctaaagaaggccgatgccgtacgcgtgatcacattcactggc
tgtatgggagagacatactttgacagtaagcccatagggttgtggaatttccgagaaaaa
gaaggtgactgcaaaggatgtacagtcagtcctcaggtggaagatagtgaggggactatt
cagtttgatggagaaggttatgcattggtcagccgccctattcgctggtatccaaacatc
tccaccgtcatgttcaagttcaggacattttcttcaagtgctctcctgatgtatcttgcc
acacgagacctgaaagattttatgagtgtagagctcactgatgggcgcataaaagtcagc
tatgatctgggttcaggaatggcttccgttgccagcaatcaaaaccataatgacgggaaa
tggaaatcattcaccctgtcaagaattcaaaaacaagccaatatatcaattgtagacata
gatactaaccaggaggagaacatagcaacttcatcatctggaaacaactttggtcttgac
ttgaaagcagatgacaaaatatattttggcggcctaccaacactgagaaacttgaggccg
gaagtaaatttgcggaaatattctggctgcctcaaagatattgaaatttcaagaacccca
tataatatactcagtagccctgattatgttggcgttaccaaaggatgttcactggagaat
gtttacaccgtaagcttccctaagcctggttttgtggagttggcccctgtgccaattaat
gtaggaacagaaatcaacctgtccttcagcaccaagaatgagtctggggtcattctcttg
ggaagtggagggacaccagcaccacctagaagaaaacgaaggcagactggtcaggcctat
tatgcgatattcctgaacaaaggccgtctggaagtgcatctctccacaggcgcacgaaca
atgaggaaaatcgtcatcaaaccagagccgagtctgtttcacgacgggagagaacattcc
gttcatgttgagagaactagaggcatctttactgttcaagttgatgaagacagaagacat
gtgcaaaacatgactgtggaacaggctattgaagttaaaaagctttttgttgggggtgct
ccactggaatttcaaccttcccccctcaggaacattcctccttttgaaggctgtatatgg
aacctagttattaactccgtccccatggactttgcacagcctgtatccttcaaaaatgca
gacattggtcgctgtgcagatcagaagccccctgaggatgaagatggagcagttcctgct
gagatacttatcctcccagagccagttcccacacctgccttccctacacccaccccagtt
ctggcacatggtccttgtgctgtagattcagaaccagcccttttgctggggagtaagcag
tttgggctttcaaaaaatagtcacattgcaattgcatttgatgacaccaaggttaagaac
cgcctcacaattgagtttgaagtgcgaaccgaagctgaatcgggattgcttttttacatg
gctcggatcaatcatgctgactttgctactgttcagctgagaaatggattgccctacttc
agttatgacttgggaagtggtgacaccaaaaccatgatccccaccaaaatcaatgatggc
cagtggcacaagattaagattatgcgaattaagcaagaaggaattctttatgtagatgat
gcctccaacagaaccatcagtcccaagaaagctgatatcctggacgttgtaggaatgcta
tatgttggagggctgcccatcaactatactacccgaagaataggtccagtcacctacagc
attgagggctgcatcaggaatcttcagatggcagaggcccctgctgaccttgaaaagcca
acctccagcttccatgtcgggacatgttttgcagatgctcagaagggaacatacttcgat
ggaacaggttttgccacagcagttggtggattcaaggtgggattggaccttcttgtagaa
tttgaattccgcacaactaggaccactggagttcttctgggaattagcagccaaaaaatg
gatggaatgggtatcgaaatgattgatgaaaagctcatgtttcatgtggacaatggagcc
ggccgattcactgctgtctatgatgctgggatcccagggcgtttgtgtgatggacagtgg
cataaggtcactgccaacaagatcaaacaccgcatcgagctgacggttgatgggaaccag
gtggaagcccaaagcccaaacccagcttctacatcagctgacacaaatgaccctgtgttt
gttggaggtttcccagatggcctcaatcagtttggcctgacaaccaacattcggttccga
ggttgcatccgatccctgaggctcaccaaaggaactggcaagccactggaggttaatttt
gccaaagccttggagctgagaggtgttcaacctgtatcgtgcccagccaactga
DBGET
integrated database retrieval system
