Loxodonta africana (African savanna elephant): 100677422
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Entry
100677422 CDS
T04351
Symbol
VAV2
Name
(RefSeq) guanine nucleotide exchange factor VAV2
KO
K05730
guanine nucleotide exchange factor VAV
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav04015
Rap1 signaling pathway
lav04024
cAMP signaling pathway
lav04062
Chemokine signaling pathway
lav04510
Focal adhesion
lav04650
Natural killer cell mediated cytotoxicity
lav04660
T cell receptor signaling pathway
lav04662
B cell receptor signaling pathway
lav04664
Fc epsilon RI signaling pathway
lav04666
Fc gamma R-mediated phagocytosis
lav04670
Leukocyte transendothelial migration
lav04810
Regulation of actin cytoskeleton
lav05135
Yersinia infection
lav05205
Proteoglycans in cancer
lav05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
100677422 (VAV2)
04024 cAMP signaling pathway
100677422 (VAV2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
100677422 (VAV2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
100677422 (VAV2)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
100677422 (VAV2)
04660 T cell receptor signaling pathway
100677422 (VAV2)
04662 B cell receptor signaling pathway
100677422 (VAV2)
04664 Fc epsilon RI signaling pathway
100677422 (VAV2)
04666 Fc gamma R-mediated phagocytosis
100677422 (VAV2)
04670 Leukocyte transendothelial migration
100677422 (VAV2)
04062 Chemokine signaling pathway
100677422 (VAV2)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
100677422 (VAV2)
09171 Infectious disease: bacterial
05135 Yersinia infection
100677422 (VAV2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
100677422 (VAV2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
RhoGEF
CAMSAP_CH
CH
SH3_2
SH2
SH3_1
SH3_9
C1_1
DUF7145
PLU-1
CDC24
C1_2
SH2_2
PH
ANC1_spectrin
Motif
Other DBs
NCBI-GeneID:
100677422
NCBI-ProteinID:
XP_023398103
LinkDB
All DBs
Position
Unknown
AA seq
906 aa
AA seq
DB search
MEQWRQCGRWLIDCKVLPPNHRVVWPSAAVFDLAQALRDGVLLCQLLHNLSPGSIDLKDI
NFRPQMSQFLCLKNIRTFLKVCHDKFGLRNSELFDPFDLFDVRDFGKVISAVSRLSLHSI
AQNKGIRPFPSEETAENDDDVYRSLEELADEHDLGEDIYDCVPCEDEGDDIYEDIIKVEV
QQPMKMGMTEDDKRSCCLLEIQETEAKYYRTLEDIEKNYMSPLRLVLSPGDMAAIFTNLE
DLIKVHHSFLRAIDLSMMAGGSTLAKVFLDFKERLLIYGEYCSHMEHAQNTLNQLLAGRE
DFRQKVEECTLKVQEGKFKLQDLLVVPMQRVLKYHLLLKELLSHSTDRPERQQLKEALEA
MQDLAMYINEVKRDKETLKKISEFQSSIENLQVKLEEFGRPKIDGELKVRSIVNHTKQDR
AGNELSADGCGEGRAGVHRRWSGRGELGFTGDGQAYTHAGMCTQDRHVSCLLLQWSYGFY
LVHLQGKQGFQFFCKTEDMKRKWVEQFEMAMSNIKPDKANANHHSFQMYTFDKTTNCKAC
KMFLRGTFYQGYLCTKCGVGAHKECLEVMPPCKISFPADPDASGAGPGPKMVAVQNYHGN
PAPPGKPVLTFQTGDVMELLRGDPESQWWEGRLVQTRKLGYFPSSSVKPCPVDGRPPIGR
PPSREIDYTAYPWFAGNMERQQTDNLLKAHASGTYLVRERPAEAERFAISIKFNDEVKHI
KVVEKDSWIHITEAKKFESLLELVEYYQCHSLKESFKQLDTTLKYPYKSRERVACRASSR
SPASCAFYNFSFLSPQGLSFASQGSSAPFWSVFTPRVIGTAVARYNFAARDMRELSLREG
DVVKIYSRIGGDQGWWKGEANGRQLKSLVPVGKRRLQRSSRALGSRHTVRSGPRPDSALS
CFVPPS
NT seq
2721 nt
NT seq
+upstream
nt +downstream
nt
atggagcagtggcggcagtgcggccgctggctcatcgactgcaaggtcctgccgcccaac
caccgggtcgtgtggccctcggctgcggtcttcgacctggctcaggcgctgcgcgatggc
gtcctgctctgccagctgctgcacaacctgtccccaggctccatcgacctcaaggacatt
aacttccggccgcagatgtcccagtttctgtgtttgaagaatatccgcaccttccttaaa
gtctgccacgataaatttggactcagaaacagtgagctgttcgacccctttgacctcttc
gatgtccgagattttggaaaggtcatctcggccgtgtccaggctctctctgcacagcatc
gcacagaacaaaggcatcaggccttttccctcagaggagaccgcagaaaacgatgatgac
gtgtaccgaagcctggaggagctggcggacgagcacgacctgggggaggacatctatgac
tgcgtcccgtgtgaggatgaaggagacgacatctatgaggacatcatcaaggtggaggtg
cagcagcccatgaaaatgggcatgacagaggatgacaagaggagctgctgcttgctggaa
atccaggagactgaggccaagtactaccggaccctcgaggacatcgagaagaactacatg
agcccgctgaggctggtgctgagccccggggacatggcggccatcttcaccaacctggag
gacctgattaaggtgcaccacagcttcctgcgggccatcgacctatccatgatggcgggg
ggcagcaccctggccaaggtcttcctcgacttcaaggaaaggctcctcatttatggcgag
tactgcagccacatggaacacgcccagaacacgctgaaccagctcctcgctggccgcgag
gacttcaggcagaaggtcgaggagtgcacgctgaaggtccaggaaggcaagttcaaactg
caggacctgcttgtggtgcccatgcagagggtgctcaagtaccacctcctcctgaaggaa
cttctgagccattccactgaccggcctgagagacaacagctcaaagaagctctggaagcc
atgcaggacttggccatgtacatcaatgaggtcaaacgggacaaagagaccttgaagaaa
atcagtgagttccagagctccattgaaaacctgcaagtgaaactggaggagtttgggagg
ccgaaaatagacggcgagttgaaagtccgctccatagtcaaccacaccaagcaggacaga
gccggcaatgagctttccgcagacggctgcggggaggggcgagccggggttcacaggagg
tggtcagggaggggcgagttggggttcacgggagatggtcaggcgtacacacatgcaggc
atgtgcacacaggaccgacatgtttcctgtctcctcctgcagtggtcctatggcttctat
ctggtccaccttcaaggaaagcagggcttccagttcttctgcaagacggaagacatgaag
aggaagtgggtggagcagtttgagatggccatgtcaaatatcaagccagacaaagccaat
gccaaccaccacagcttccagatgtacacatttgacaagaccaccaactgcaaagcctgc
aagatgttcctcaggggtaccttctaccagggctacctgtgtaccaagtgtggcgttggg
gcacacaaagagtgtctggaggtgatgccgccctgcaagatcagttttcctgcagacccg
gacgcctctggagcgggaccaggtcccaagatggtggctgtgcagaattaccatggcaac
cccgcgccccctggaaagccggtgctcaccttccagacgggtgatgtgatggaactgctt
cgaggggaccctgagtcgcagtggtgggagggtcggctggtccaaaccaggaagttgggt
tatttcccaagttcgtctgtgaagccctgccctgtggacggaaggccacccatcggccgg
ccaccgtcccgggagatcgactacaccgcatacccctggtttgctggcaacatggagagg
cagcagacagacaacctgctcaaggcccacgccagcggtacctacctggtccgggagcgg
ccggctgaggcggagcgcttcgcaatcagcatcaagttcaatgacgaggtcaagcatatc
aaggtggtggagaaggacagctggatccacatcacagaagcaaagaagttcgaaagcctc
ttggagctggtggagtactaccagtgccactcactcaaggagagcttcaagcagctggac
accacgctcaagtacccctacaagtcacgggagcgcgtggcctgcagggcctccagccgg
tccccagcttcctgcgctttctacaacttttcttttctcagtcctcagggcctcagcttt
gcttctcagggctcctccgctcccttctggtcagtgttcacgccccgagtcatcggcacg
gctgtggccaggtataactttgcagcccgggacatgcgggagctctcattgcgagaaggc
gacgtggtgaagatttacagccgcatcggcggggaccagggctggtggaaaggcgaggcc
aatgggcggcagctgaaaagcctggtgccagtggggaaacggaggctgcagagatctagc
cgggcactaggaagcagacatactgtcagatctggacccaggcctgattcagccctgtcc
tgttttgtgccaccttcatga
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