Loxodonta africana (African savanna elephant): 100677530
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Entry
100677530 CDS
T04351
Symbol
NDUFS1
Name
(RefSeq) NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial isoform X1
KO
K03934
NADH dehydrogenase (ubiquinone) Fe-S protein 1 [EC:
7.1.1.2
]
Organism
lav
Loxodonta africana (African savanna elephant)
Pathway
lav00190
Oxidative phosphorylation
lav01100
Metabolic pathways
lav04714
Thermogenesis
lav04723
Retrograde endocannabinoid signaling
lav04932
Non-alcoholic fatty liver disease
lav05010
Alzheimer disease
lav05012
Parkinson disease
lav05014
Amyotrophic lateral sclerosis
lav05016
Huntington disease
lav05020
Prion disease
lav05022
Pathways of neurodegeneration - multiple diseases
lav05208
Chemical carcinogenesis - reactive oxygen species
lav05415
Diabetic cardiomyopathy
Module
lav_M00143
NADH dehydrogenase (ubiquinone) Fe-S protein/flavoprotein complex, mitochondria
Brite
KEGG Orthology (KO) [BR:
lav00001
]
09100 Metabolism
09102 Energy metabolism
00190 Oxidative phosphorylation
100677530 (NDUFS1)
09150 Organismal Systems
09156 Nervous system
04723 Retrograde endocannabinoid signaling
100677530 (NDUFS1)
09159 Environmental adaptation
04714 Thermogenesis
100677530 (NDUFS1)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
100677530 (NDUFS1)
09164 Neurodegenerative disease
05010 Alzheimer disease
100677530 (NDUFS1)
05012 Parkinson disease
100677530 (NDUFS1)
05014 Amyotrophic lateral sclerosis
100677530 (NDUFS1)
05016 Huntington disease
100677530 (NDUFS1)
05020 Prion disease
100677530 (NDUFS1)
05022 Pathways of neurodegeneration - multiple diseases
100677530 (NDUFS1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
100677530 (NDUFS1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100677530 (NDUFS1)
Enzymes [BR:
lav01000
]
7. Translocases
7.1 Catalysing the translocation of protons
7.1.1 Linked to oxidoreductase reactions
7.1.1.2 NADH:ubiquinone reductase (H+-translocating)
100677530 (NDUFS1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Molybdopterin
Fer4_Nqo3
Fer4_NDSU1
Fer2_4
NADH-G_4Fe-4S_3
NADH_dhqG_C
Fer2
Motif
Other DBs
NCBI-GeneID:
100677530
NCBI-ProteinID:
XP_003406159
UniProt:
G3TBZ7
LinkDB
All DBs
Position
Unknown
AA seq
727 aa
AA seq
DB search
MIRIPLRRALAGLAKSPKGCVRATSTAASNLIEVFVDGQSIMVEPGTTVLQACEKVGIQI
PRFCYHERLSVAGNCRMCLVEIEKAPKVVAACAMPVMKGWNILTNSEKSRKAREGVMEFL
LANHPLDCPICDQGGECDLQDQSMMFGSDRSRFLEGKRAVEDKNIGPLVKTIMTRCIQCT
RCIRFASEIAGVDDLGTTGRGNDMQVGTYIEKMFMSELSGNIIDICPVGALTSKPYAFTA
RPWETRKTESIDVMDAVGSNIVVSTRTGEVMRILPRMHEDINEEWISDKTRFAYDGLKRQ
RLTEPMVRNEKGLLTYTSWEDALSRVAGKLQSFQGKGVAAIAGGFVDAEALVALKDLLNR
VDSDTLCTEEVFPTAGAGTDLRSNYLLNTTIAGVEEADVLLLVGTNPRFEAPLFNARIRK
SWLHNDLKVALIGSPVDLTYRYDHLGDSPQVLQDVASDEHPFSQVLKEAKKPMVVLGSSA
LQRNDGAAILAAVSSIAQKIRTSSGVAGDWKVMNILHRIASQVAALDLGYKPGVEAVRKN
PPKVLFLLGADGGCITRQDLPKDCFIIYQGHHGDVGAPIADVILPGAAYTEKSATYVNTE
GRAQQTNVAVTPPGLAREDWKIIRALSEIAGVTLPYDTLDQVRNRLEEVSPNLVRYDDVE
GANYFQQANELSKLVNQQLLADPLVPPQLTIKDFYMTDSISRASQTMAKCVKAVTEGAQA
VEEPSIC
NT seq
2184 nt
NT seq
+upstream
nt +downstream
nt
atgataaggatacctctaagaagggccttggcaggccttgctaagtctcctaaaggatgt
gttcgtgcaacttccacagcagcaagcaacttgattgaagtatttgtggatggtcaatct
atcatggtggaaccaggaactactgtcctccaagcttgtgaaaaggttggcatacagatc
cctcgattctgttaccatgaaagattgtctgttgctggaaactgcaggatgtgccttgtt
gaaattgagaaagctcctaaggttgtagctgcttgtgccatgcctgtaatgaagggttgg
aatatcctgaccaactcagagaagtctaggaaagccagagaaggtgtgatggagttctta
ctagcaaatcacccactggactgtcctatttgtgaccagggaggtgaatgtgatctacag
gaccagtccatgatgtttggaagtgataggagccgatttttagaggggaaacgtgctgtg
gaggacaagaacattgggccgttggtaaagaccattatgactagatgtatacagtgtact
cgctgcatcaggtttgctagcgagattgcaggagtagatgatttgggaacaacaggcaga
ggaaatgatatgcaagttggcacatacattgaaaagatgttcatgtcagagctgtctggg
aatatcattgatatctgccctgtaggtgccctgacctctaagccctatgccttcactgcc
cggccctgggaaacaagaaagacagaatccattgatgtaatggatgcagttgggagtaat
attgtggtaagcacaagaactggagaggtgatgaggattttgcccaggatgcatgaggac
attaatgaagagtggatctctgataaaactagatttgcctatgatgggctaaaacgtcaa
agactcaccgagccaatggtcagaaacgaaaaagggcttttaacctatacctcctgggaa
gatgcactctctcgtgtagctggaaagttgcagagttttcaaggcaagggtgtagcagca
attgcaggtggttttgtggatgctgaagccctggtagctctcaaagatttacttaataga
gtggactctgacaccctatgtactgaagaagtcttccccaccgcaggagctggcacagat
ttacgttctaattatcttcttaatactacaattgctggtgtggaagaggcagatgttctc
cttctggttggtacaaatccacgttttgaggcaccactatttaatgccagaattcgaaag
agctggcttcataatgacttaaaagtggccctcataggcagcccagtggatctgacgtac
agatatgaccacctgggagactctccccaagttcttcaagacgttgcttcagatgagcat
cccttcagccaggtcctaaaggaagctaaaaaaccaatggtggttttagggagttctgca
cttcagagaaatgacggtgctgcaatccttgcggctgtttccagcattgcacaaaagatt
cggacaagcagtggtgttgctggtgattggaaagttatgaatattcttcacaggattgca
agccaggtagctgctttggaccttggctataaacctggggtggaagcagttcgaaagaac
cctcccaaagtgctgtttctcctaggagcagatggaggttgtatcactcgacaggatttg
ccaaaggattgtttcattatttatcaaggacatcatggtgatgtcggagctcctatagct
gatgttattctcccaggagctgcttacacagagaagtctgctacttacgtcaataccgag
ggcagagctcagcagactaatgtagctgtgacaccacctggtttggcaagagaagactgg
aaaattataagagcactatctgagattgctggtgtaactcttccgtatgatactctggat
caagtgaggaacagattggaagaagtttctcctaatcttgttcgatatgatgatgttgaa
ggagccaactacttccagcaagcaaatgagctctcaaagctagtaaatcagcaactgctt
gctgatccgcttgttccccctcagctaacaataaaagacttctacatgacagattcaatt
agcagagcctcacaaacaatggccaagtgtgtcaaagctgtaacagagggtgcccaggca
gtggaggaaccatccatatgctga
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