Lactobacillus amylovorus GRL1118: LAB52_01310
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Entry
LAB52_01310 CDS
T01954
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lay
Lactobacillus amylovorus GRL1118
Pathway
lay00300
Lysine biosynthesis
lay00550
Peptidoglycan biosynthesis
lay01100
Metabolic pathways
lay01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lay00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LAB52_01310
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LAB52_01310
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LAB52_01310
Enzymes [BR:
lay01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LAB52_01310
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
RecA-like_ORC2
LPD11
Motif
Other DBs
NCBI-ProteinID:
AEA31247
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Position
260285..261652
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AA seq
455 aa
AA seq
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MKMQMAEIAKALNTTCEGDDQTVITSVAFDSRKITNGGLFVPLEGERDGHDFVAGAISNG
ASATLWKKGHPNKPENIAVIEVDDPLSAMQDLARYYLRKVNPTVVGITGSNGKTTTKDMV
AAVLSKRFNVHKTQANFNNEIGVPMTILEMKPNTEILVLEMGMDRPGQLHHLSELTHPDV
AVITMIGEAHIEFFGTRDKIADAKMEITDFLREDGEFIFNGDEPLLQERAKKLDQVKATF
GFRDEDTVHATGFKSYMHHATFTINDSEQKFSIPMIGKHNVSNAMAAISVGRHFGESDEE
IASSLSNFKPTANRMEWEKGDAGEAIMSDVYNSNPTAVRAVVTSFGQVEVKDDGCRIAVL
GDMLELGKNSPALHAGLSDTLDPQIINEVYLYGPEMKNLYDALKDKYKPEHLHYYTQDQM
DRMIDDLKNDIKPDDIVVLKGSHGMHLENVLARLR
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcaaatggcggaaattgccaaggctttaaatacaacttgtgaaggcgacgat
caaacagttattacttctgttgcctttgactccagaaagatcacaaatggtggtttgttt
gtaccacttgaaggtgaacgtgacggacatgatttcgtagctggtgctattagtaatggt
gcttctgctacgctttggaagaagggacaccctaacaaaccagagaatattgcggtaatc
gaagtagatgatccacttagcgcaatgcaagatttggcacgctactacttacgcaaggtt
aacccaactgtagttggtattactggttcaaatggtaagactactactaaagacatggta
gctgccgttttgtccaagcgttttaacgttcataagacacaagccaactttaataacgag
attggtgtgccaatgaccattcttgaaatgaagccaaatactgaaattttggtacttgaa
atgggtatggacagacctggtcaattacaccacttaagtgaattgactcatcctgatgta
gccgtaatcactatgattggtgaagctcacatcgaattctttggtacacgtgacaagatt
gccgatgccaagatggaaattaccgacttcttgcgtgaagacggtgaatttatcttcaac
ggtgatgaaccattgttacaagaacgtgctaagaagcttgatcaagttaaggctaccttt
ggcttcagggatgaagatacagttcacgctactggctttaagagctacatgcaccatgct
actttcactattaacgattcagagcaaaagttctcaatcccaatgattggtaagcacaac
gtttcaaacgctatggctgcaattagtgttggtcgtcactttggcgaaagcgatgaagaa
attgcctcatcactttctaacttcaagccaactgctaacagaatggagtgggaaaagggc
gatgccggcgaagcaattatgagcgacgtttataactctaacccaactgctgttagagcc
gttgttactagctttggtcaagttgaagttaaagacgacggttgtagaattgccgtcttg
ggcgatatgcttgaattaggtaagaactcccctgcacttcacgctggtttaagtgatact
ttggatccacaaatcatcaatgaagtatatttgtacggccctgaaatgaagaacttgtac
gatgcattgaaagacaagtataagccagaacatttgcattattatacacaagatcaaatg
gatcgtatgatcgacgatcttaaaaatgatattaagccggacgacattgttgtattaaag
ggttcacacgggatgcaccttgaaaatgtcttagcccgactaagatag
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