Leptopilina boulardi: 127278644 Help Entry 127278644         CDS       T08910                                  Name (RefSeq) ryanodine receptor isoform X1   KO K04962   ryanodine receptor 2 Organism lbd  Leptopilina boulardi Brite KEGG Orthology (KO) [BR:lbd00001]  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:lbd04040]     127278644    04990 Domain-containing proteins not elsewhere classified [BR:lbd04990]     127278644 Ion channels [BR:lbd04040]  Voltage-gated cation channels   Ryanodine receptor    127278644 Domain-containing proteins not elsewhere classified [BR:lbd04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    127278644 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR SPRY Ins145_P3_rec MIR RR_TM4-6 RIH_assoc Ion_trans EF-hand_7 Serglycin Motif Other DBs NCBI-GeneID:  127278644 NCBI-ProteinID:  XP_051156404 LinkDB All DBs Position Unknown AA seq 5130 aa AA seqDB search MADSEGGSEQDDVSFLRTEDMVCLSCTATGERVCLAAEGFGNRHCFLENIADKNIPPDLS QCVFVIEQALSVRALQELVTAAGSETQQESLGKGTGSGHRTLLYGNAILLRHLNSDMYLA CLSTSSSNDKLAFDVGLQEHSQGEACWWTVHPASKQRSEGEKVRVGDDLILVSVATERYL HTTKENNLSVVNASFHVTHWSVQPYGTGISRMKYVGYVFGGDVLRFFHGGDECLTIPSTW STAPNQNIVIYEGGSVMSQARSLWRLELARTKWSGGFINWMHPMRIRHLTTGRYLGVNEA NNELYLVDKKEATTDICNFLLRQEKDDQKVALEDKDLEVIGLPIIKYGDSTVIMQHAQTS LWVSYKSYETKKKGVGKVEEKQAVLQEEGKMDDGLDFSRSQEEESRTARVIRKCSSLFTQ FITGLETLQIDRRASQFFKNVNLNEMVMCLEDLINYFAQPEDDMEHEEKQNKIRALRNRQ DLFQEEGILNLILEAIDKINVITSQGFLVALSSDESGQSWDQISGYLYQLLAAIIKGNHT NCAQFANSNRLNWLFSRLGSQASSEGTGMLDVLHCVLIDSPEALNMMRDEHIKVIISLLE KHGRDPKVLDVLCSLCVGNGVAVRSSQNNICDFLLPGKNLLLQTQLVDHVASVRPNIFVG RVEGSALYQKWYFEVTVDHIEQTTHMMPHLRIGWANIAGYVPYPGGGEKWGGNGVGDDLY SFGFDGSYLWTGGRKTRVIEDATEPFIKKTDVIGCSLDLTVPVINFAFNGIPINGSFRNF NLDGMFFPVISCSSKLSCRFLLGGDHGRLKFEPPEEFSPLVESLLPQQILSLDPCFYFGN MGKVVIAGPWLVEDDTAFVPAPVDTSMINLPSYVEQIRDKLAENIHEMWAMNKIEAGWIF GEQRDDLNKIHPCIVQFERLPNAEKRYDTQLAVQTLKTILALGYYITMDKPPSRIKTLRL PNEPFLQSSGYKPAPLDLTAITLTPKMEELVDQLAENTHNLWAKERISQGWTYGLNEDSE MRRSPHLVPYPKVDDAIKKANRDTASETVRTLLVYGYMLDPPTGEQHEALLLEANRLRQL SFRTYRVERHYAVTSGKWYFEFQVLTAGPMRVGWARADCPPGNMLGNDDSTWAFDGYNEE KVYSGTAETFGKQWQVGDVVGVFLDLIDRTISFSLNGELLMDALGGETSFADVQGDSFVP AFTLGVGQKAKLTFGQDVDTLKFFTTCGLQEGYEPFCVNMNRPVTYWYTKDQPIYENTDD MSDTRIDVARIPAGSDSPPCLKISHNTFETMEKANWEFLRLSLPVICGSTFISDADKMRR WQEIKMKQNRLLAEQMEQVQQATPSAHIEQIMRSGFSMSDIKGLQRNYSEDAVENDEMMK ESPLPIQRNKPSRPPRKGSVPRGLDRATSEAEMNGYGEMNGDLKDDKKKRGRSPFRKRSI EMEDIASNVSRFFSRKAKSPDAKAKTPEPFARSDVSDRSMKQTTLSTSGSRTAQIRTSTN DLTKMMPPQIPERNAPKAMSVMTGTGIESIGNEIFDADCLKLMNEYFYGVRIFPGQDPTH VYVGWVTSQYHIHTKDFNLSKVRKVSVIITDNYDQPLEQVDRQSCYMVRADELYNEVTQD ASGKGASQGMFIGCFVDTATGWISFTCEGKETSHKFKMEPDTKLFPAIFVEATSKEILQI ELGRTSTTLPLSAAVLQNSERHVIPQFPPRLKVQCLKPHQWARVPNQSLQVHALKLSDIR GWSMLCEDAISMLALHIPEEDRCIDILELIEMDKMLSFHAHTLTLYAALCYQSNYRAAHA LCQHVDQKQLLYAIRAEYMSGPLRQGFYDLLIALHLESHATTMEVCKNEYVIPLGQELKD LYEDLEMRHSLRYLETESVRPQMKMSEIGENQNIENIKSLYSPHFPLDIVRDYVMMALNE AVEVNQVHNRDPIGGSNENLFLPLIKLVDRLLLVGMLRNEDIQKLLTMINPETWDDTFDK EGKDEHKKGLLHMKMAEGAKLQMCYLLHHLNDIQLRHRVESIISFSHDFVGDLQADQLRR YIEIKQSDLPSAVAAKKTREFRCPPREQMNAILNFKNLEEEDSDNCPCGEELIAKMNEFH SELMSYVSLTALQEAADAAQEIVEIEKPGAMKRLFNFINTVKELEEEAKPEPEPQKKTAE EVFRKVLIATIVKWAEESQIETPKLVREMFSLLVRQYDTVGELIRALEKTYVINSKTKQD VAEMWVGLSQIRALLPVQMSQEEEGLVRERLWKLVNNHTFFQHPDLIRVLRIHENVMAIM INTLGRRAQAQSDGQAQAQTAEGEVPTKEKDTSHEMVVACCRFLCYFCRTSRQNQKAMFD HFDFLLENSNILLSRPSLRGSTPLDVSYSSLMENTELALALREHYLEKIAIYLSRCGLQS NSELVEKGYPDLGWDPVEGERYLDFLRFCVWVNGESVEENANLVIRLLIRRPECLGPALR GEGEGLLRAIIDANKMSERIADRRKHFKQLQDEAEGTSTGLQFEHPLPESDDDEDYIDTG AAILNFYCTLVDLLGRCAPDSSVIEQGKNESLRARAILRSLVPLDDLQGVLSLRFTLLNP AAGEERPKSDTPSGLIPGHKQSITMFLERVYGIETQELFFKLLEEAFLPDLRAATMLDRN DGYESDMALAMNRYIGNSILPLLIKHSKFYNEADNYSSLLDATLHTVYRLSKNRMLTKGQ REAVSDFLVALTSQMQPSMLLKLLRKLTVDVSNLSEYTTVALRLLTLHYDRCGKYYGSTG SSGSSPYGASSDEEKRLTMVLFSNIFDSLSKMDYDPELFGKALPCLTAIGCALPPDYSLS KNCDDEWYGSKSASTQSTDGPYNPQPINTSSVVLNNDLNQIVQKFSEHYHDAWASRKLEN GWTFGDSWSDANKTHPRLKPYNTLNDYERERYKEPVRESLKALLAIGWSVEHAEVDNKST NRNSLRRSSKSQGDSASPFNYNPHPVDMTNLTLSREMQNMAERLADNAHDIWAKKKKEEL LTVGGGIHPQLVPYDLLTDKEKRKDRERSQEFLKYLQYQGYKLHKPNRGGEAEVGGVGAA VELRFAYSLLEKLIEYLDKATINMKLLRPSDTFSRRTSFKTATRDIKFFSKVVLPLVEKY FSTHRNYFIAVATATNNVGAASLKEKEMVAALFCKLASLLRSRMAAFGADVRITVRCLQV LVKGIDAKSLVKNCPEFIRTSMLTFFNNTADDLGHIILNLQEGKFSHLRGTHLKTSTSLS YINSVILPVLTAMFDHLATCEYGSDLLLDEIQVASYKMLASLYTLGVDSTLTQDRKYLKT EIERSKPNLGSCLGAFSSCFPVAFLEPHLNKHNQFSLLNRIADHSLEAQDVMTRMESSMP TLETILSEVDQFVESEKTYTDAPHVVDVILPLLCSYLPLWWAQGPDNVNPTEGAYVSMVT SDHMNQLLKNVLKLIKKNIGNENAPWMTRIAAYTQQIIINSSEELLKDPFLPLAERVRKR TDNMFHKEESLRGFIKSSTDDTSQVEAQIQEDWQLLVRDIYSFYPLLIKYVDLQRNQWLR NNISEAEDLYNHVASIFNIWSKSQYFLREEQNFISANEIDNMVLIMPTATRRPAAVSEGA TPAGGGKKKKKHRDKKRDKDKEVQASLMVACLKRLLPVGLNLFAGREQELVQHCKDRFLK KMAEHEITEFAKTQLTLPDKIDPADEMSWQHYLYSQLGQKKDVMEPVKAQQIDDVVARIT DMAKVLYGLHMIDHPQQQSKSQYRSVVSIQRKRAVIACFRQISLHSLPRHRAINIFARTY YELWLQDENVGQEVMIEDLTQSFEDAELNKTDGKEDEGKPDPLTQLVTTFCRGAMTERSG ALQEDPLYMSYAQIISKSCGEEEEEEEGEGGGEEEGRASIHRPMHKLMEQEMEKQKLLFH QARLANRGVAEMVLLHISACKGVPSEMVMKTLELGISILRGGNIEIQKGMLNHLKEKKDV GFFTSIAGLMNSCSVLDLDAFERNTKAEGLGVGSDGAAGEKNMHDAEFTCALFRFIQLTC EGHNLDWQNYLRTQAGNTTTVNVVICTVDYLLRLQESIMDFYWHYSSRELIDPAGKANFF KAIGVASQVFNTLTEVIQGPCAQNQQALAHSRLWDAVGGFLFLFSHMQDKLSKHSSQVDL LKELLNLQKDMITMMLSMLEGNVVNGTIGKQMVDTLVESASNVELILKYFDMFLKLKDLV SSPSFLEVDLNSDGWVYPKDFKEKMEQQKSYTDEEIEFLLACCETNHDGKIDYVAFMDRF HEPAKEIGFNLAVLLTNLSEHMPNEPRLARFLETAGSVLNYFEPFLGRIEILGSNKKIER VYFEIKESNIEQWEKPQIKESKRSYFYNTVVEAGDKEKLETFIDFCEDAIFEMQHASALM AVEESGGIGKARESSYTYMTDDDDERNKDPIRRGIQAFKDGIYFFFSMFSPTNIKNKISE MQQMTIPELFIGFFKMIFYAFYYSGFGVGVVIQYFMKLLLTLMRGPHVEPVVEVKEEEEK PLRHLPALPPTPDESNMQVQAFGMDITKEEGGQLKIAPHESNVSTPHSSMEETGESTADE GAGGEEGQRALGDGVETESPVTLADLLGGEQARAQAAAAAEAAAAQQAAMAAVEAETKQE TTSERVSASSFDISQYTHRIVSFLARNFYNLKYVALVLAFCINFMLLFYKVTSLVSDEEE TNDTMADLLSEISGSGSGVGEGSGVDSGSGGEDGSSEEADVIEYVEVSEDVYYMAHVMRL MAALHSIVSLAMLVAYYHLKVPLAIFKREKEIARRVEFDGLYIAETPEDDDIKAHWDKMV ISAKTFPVNYWDKFVKKKVRQKYSEAYDFDHISNLLGMEKTSFSQQEEDGSGLIHFIVTI DWRYQIWKAGVTITDNAFLYSLWYFTFSILGNYNNFFFAAHLLDVAVGFKTLRTILQSVT HNGKQLVLTVLLLTIIVYIYTVIAFNFFRKFYIQEEDDEVDKKCHDMLTCFVFHLYKGVR AGGGIGDEIGEPDGDDYEVYRIMFDITFFFFVIIILLAIIQGLIIDAFGELRDQLESVKA NMESNCFICGLGKEYFDTVPHGFDTHVQQEHNLANYMFFLMHLINKPDTEYTGQETYVWN LYQQRSWDFFPVGDCFRKQNDAVEEEAKKK NT seq 15393 nt NT seq  +upstreamnt  +downstreamnt atggcagacagcgagggaggatctgaacaggatgacgtatccttcctccgtacggaagac atggtatgtctttcgtgtacagctacgggggaaagggtatgtttggcagccgagggtttt ggaaatcggcactgttttttggaaaacatagcagacaagaatattccgcctgatttgtca cagtgtgtatttgtaatagagcaagcactttcggtacgagcactacaagagttggtcacg gctgctgggtctgagacgcaacaagaaagtttaggaaagggtacaggatcgggtcacaga acattgctttatggcaatgcaattcttctcaggcatcttaacagtgatatgtacttagcg tgtctatccacgagttcttcaaacgataaacttgcttttgatgtcggtttacaggagcac tctcaaggagaggcttgctggtggactgtacatccggcttcgaaacaaagatcagaggga gaaaaagttcgagttggtgatgatttaattcttgtatcagtcgccacagaaagatatttg cacacgactaaagaaaataacttatcagtagtaaacgcttccttccacgtaacacattgg tctgttcaaccttatgggactggcataagtcgaatgaaatatgtaggttacgtgtttgga ggagacgtccttagattttttcatggtggtgacgaatgtctcaccataccttcgacatgg agcacagctcccaatcaaaatatagttatttacgaaggaggaagtgtaatgagtcaagct cgatccctgtggcgattggagcttgcaagaacaaaatggtctggtggatttattaattgg atgcatccaatgaggattagacatttaaccactggacgttatctaggtgttaatgaagcc aataatgaactatacctcgttgacaagaaagaggcaaccacagatatatgtaatttttta ctgcgacaagaaaaggacgatcaaaaagttgctctcgaagacaaagacctggaagttatt ggattgcccattatcaaatatggtgattcaactgttatcatgcaacatgcacaaacgagt ctttgggtgtcttacaagtcgtacgaaacgaagaaaaaaggtgttggaaaagtcgaagaa aaacaggcagttttgcaagaggaaggaaaaatggacgatggtcttgatttttcccgatca caagaagaggaatctagaactgccagagtaattagaaaatgcagtagtcttttcacacaa ttcatcacaggactagaaacgctgcagattgatcgaagggcttcccaattttttaaaaat gtaaatctcaacgaaatggttatgtgcctcgaggatttgatcaattactttgctcaacct gaagatgatatggaacacgaggaaaagcaaaataagattcgtgccttaagaaatcgtcag gatttatttcaagaggagggaatattgaatcttattttagaagctattgataaaataaat gttattacatcgcaaggatttttggttgcactttctagtgatgagagtggacaatcatgg gaccaaatatccggttatttgtatcaattattggctgccattattaaaggcaatcatacg aattgtgcacaatttgccaatagcaatcgtcttaattggctcttcagtcggttaggatca caggcatcaagcgagggaactggaatgttagatgtgttgcattgtgtgcttattgactcg ccagaagcattaaacatgatgagggatgagcacatcaaggtgataatatcccttttggag aagcatggaagagatccaaaagtactggacgttttgtgttccctttgcgtgggaaatgga gtggcagtacgttcgtcgcagaacaatatttgtgattttctactaccgggaaaaaattta ttactacaaacacaattagtggatcatgtggcgagtgtgagaccaaatattttcgttggc agagtcgagggatcggcgctctatcaaaaatggtattttgaagtaacagtggatcatatt gagcagacaacacacatgatgccacatttgaggattggatgggccaatatcgcgggatat gttccctatccgggtggtggtgaaaaatggggtggcaatggagttggtgatgatctttat tcatttggattcgatggctcatatctttggacgggtggtcgtaaaactcgtgtaattgaa gacgcaaccgagccatttatcaagaaaactgatgtaattggatgttctctggatttgacg gttccggtgataaattttgccttcaatggaataccaattaatggttcatttcgaaatttc aatctcgatggaatgttctttccagtgattagttgctcgtcaaaattatcatgtcgattt cttttgggtggtgatcatggacgattgaaattcgaaccacctgaagaattttcacccttg gttgagagtcttcttccacagcagattctatcgttggatccttgtttttattttggaaat atgggcaaagtggtgattgccggtccatggcttgttgaagatgacactgcctttgtgcca gctccggttgacacgtcgatgatcaatctaccgagttacgttgaacaaataagggacaaa cttgctgaaaatattcacgaaatgtgggctatgaataaaattgaagctggatggattttt ggtgaacagagggatgatcttaataagatacatccttgtattgtacaatttgagagatta ccaaacgctgagaagagatatgatacacaattggctgttcagactttaaagacaattctt gccttggggtactatataactatggataaaccaccatcgaggattaagacattgagattg ccgaatgaaccttttttgcagagcagtggatataagccagcgccacttgatttaactgcc attactttgacaccgaaaatggaggaacttgttgatcaattggcggaaaatactcataat ttatgggcgaaggagagaatcagccagggctggacttatggattaaatgaggattcagag atgagacgaagtcctcatcttgttccttatccaaaagttgatgacgctatcaagaaagct aatcgtgacactgctagtgaaactgttcggactttacttgtttatggatatatgttggat ccaccaactggagagcagcatgaagcactgctgctggaagcgaatcgattacgtcaattg tcgttcagaacttatcgagtggagaggcattatgctgttacgagtggaaaatggtatttt gaatttcaagttttgactgctggaccaatgagagtcggatgggccagggctgattgtcca ccgggaaatatgttgggcaatgatgacagtacctgggcattcgatggttataacgaggaa aaagtttactcgggcactgctgaaacattcggtaaacaatggcaagttggagacgttgtt ggggttttcctggatcttatagatcgaacaattagcttctcgctgaatggagaacttctc atggatgctttgggaggagaaacttcatttgcagacgtccagggagactcatttgttcca gctttcactctgggggtcggacaaaaggctaaattaacatttggacaagatgttgataca ctgaaatttttcaccacctgtggtttacaggagggatatgaacctttttgcgtaaatatg aatcgaccggtgacctattggtacacaaaggatcagccaatttatgaaaatacagatgac atgtccgacacgagaatcgacgtggcgagaattccagccggttcagattcaccaccatgt ttaaaaatttcacacaatacttttgaaacaatggaaaaggcaaattgggaatttttacgt ctttcgttgccagttatttgtggttctacttttatttccgatgctgataaaatgagacga tggcaggaaattaaaatgaaacaaaatagacttttagctgaacaaatggaacaagtgcaa caagcaacaccttccgctcatattgaacaaatcatgagatctggatttagcatgagcgac attaaaggattacagagaaattattctgaagatgcagtggaaaatgatgaaatgatgaaa gaatcaccacttccgattcaacgaaataaaccatcaagaccgccaagaaaaggttctgtt cctcggggtctagatcgagcaaccagtgaagctgaaatgaacggttatggagaaatgaat ggtgatcttaaggatgacaagaaaaaaagaggacgatcaccgtttcgcaagcgtagtatc gaaatggaagatatcgcttcgaacgtgtctagatttttctcgaggaaggcaaaatctcca gacgcaaaggccaagactccggaaccatttgcgagatccgatgtttctgataggagcatg aagcaaacaactttgtcaacttctggcagtcgaacagctcaaattagaacttcaacgaac gatttgacaaaaatgatgccaccacaaattcccgaaagaaatgcaccgaaagcaatgtca gtaatgactggaactggaatcgaatcaattggaaatgaaattttcgatgctgattgttta aaattaatgaacgaatatttttatggtgtacgaatttttcccggtcaggatccaactcac gtttatgttggttgggttacatcgcaatatcacattcacaccaaggattttaatttgtca aaagttcgaaaagtatccgtgatcatcactgacaattatgatcagcctttggaacaagtg gatcgtcaaagttgctacatggttcgagcagatgaactttacaacgaggtgacacaggac gcatcgggtaaaggagcatcacagggaatgtttattggttgttttgttgatacagccacg ggttggataagtttcacctgtgagggaaaggaaacgagtcataaatttaaaatggaaccc gatactaaactctttccagcaatatttgtcgaagcgactagtaaagaaattttgcaaatt gaacttggaaggacctcgactacacttccattatcggcagctgttttacagaattcagag cgtcatgtgattccacaatttccacctagactgaaggtgcagtgcttgaaacctcatcaa tgggccagagtaccaaatcaatctcttcaagttcatgctttaaaattatctgatattcga ggatggtccatgctctgcgaagatgctatctcaatgttggcacttcatatacctgaagag gatcgttgtatcgacattttggaattaattgaaatggataagatgctgagttttcatgca cacacactgacgctttatgccgcattgtgctaccaatcgaattatagagcagcacacgct ttgtgtcaacatgttgatcagaaacaattattgtatgcaataagagctgaatatatgtca ggacccttgcgacaaggattttatgatcttcttatcgcgttgcatctcgagtctcatgcc acgacaatggaagtttgcaaaaatgaatacgtcattccattaggacaagaattgaaagat ttatatgaagatttagaaatgagacatagtttgaggtacctagaaactgagtctgttcgc cctcaaatgaaaatgagtgaaataggagagaatcagaatattgaaaacatcaaaagtcta tacagtccacatttccctctggatattgttcgagattatgtaatgatggctctaaatgaa gctgttgaagtcaatcaggtgcataacagagatccaatcggaggcagtaacgaaaatcta tttttacctctaataaaattagtggacagacttctattagttggaatgctgagaaacgaa gacatacaaaaattgctaactatgataaatccagaaacatgggatgacacttttgataaa gagggaaaagacgaacacaaaaaaggacttttacacatgaaaatggcagagggagcaaaa ttgcaaatgtgttatttgcttcatcatttgaatgacattcaattgcgtcatcgtgttgag tcgataatatcatttagtcacgatttcgttggtgatttacaagctgatcaattaagaaga tacattgaaatcaaacaatccgatcttccttcagctgtagctgcaaaaaagacaagagaa tttcgatgtcctcctcgtgagcagatgaatgctattttgaattttaaaaatctcgaggaa gaggacagtgataattgtccatgtggcgaagaacttatagcaaaaatgaacgaatttcac agtgaactaatgtcatatgtctcgttgactgctcttcaagaggctgctgatgctgctcaa gagattgtcgaaattgagaaacctggagccatgaagagactctttaatttcatcaatact gtcaaggaacttgaggaggaagccaaacctgaaccggagccacaaaaaaagacggctgaa gaggtgtttagaaaagttctgatagcaacaatcgtcaagtgggccgaagaatcacaaatt gagactccaaaattagttcgtgagatgtttagccttcttgttcgtcagtacgatacagtt ggagaattgatacgagctttggaaaaaacatacgtgattaatagtaaaacgaaacaagat gtcgcagaaatgtgggtgggattaagtcaaattcgagcacttttacctgttcagatgtcg caagaggaagaaggtttggtgagagaacgtctttggaaattggtgaacaatcatacattt ttccagcatccagatttaattcgagttctaaggatacatgagaatgtgatggcaattatg attaacactctcggtagaagagctcaggcacaatctgatggtcaagctcaagctcaaaca gctgaaggtgaagttccaactaaagagaaggatacatctcacgagatggttgttgcttgt tgtcgatttttgtgttatttctgcagaacttctcgacaaaatcaaaaagccatgtttgat cattttgattttctgctggagaacagtaatattttattgtcaagaccttcactaagagga tcaacacctcttgatgtgtcttattcatcgctgatggagaatacagaattggctcttgca ttaagggaacattatcttgaaaaaattgccatttatctttcacgttgtggattacagtcg aattccgagttggtggaaaaaggttatcctgatttaggttgggatcctgttgagggagaa cgttatcttgactttcttcgattttgtgtctgggtcaatggcgagagtgttgaagagaat gcgaatctcgtgattagattgttgattcgacgaccagagtgtttgggtccagctcttcgt ggagaaggtgaaggattattgcgagcaattatagatgctaacaaaatgtccgaacggatt gctgatcgtcgaaaacattttaaacagctccaagatgaagctgaaggaacttcaacagga ctacagtttgagcatcccttaccagaatcagacgatgatgaagattacatagacactggt gcagctattctcaatttttactgtacattggttgatttattgggacgttgtgctcccgac tcttctgtgattgaacaaggaaaaaatgaatcacttcgagctagggcaattttaagatca ctggtacctttggatgatcttcaaggagttctttcgttgcgttttacattgctcaatcca gcagcaggtgaagagagaccaaaaagtgacacaccgtctggattgattccaggtcataag caaagtatcacaatgtttttggaaagagtttatggaatcgagacacaggaattatttttc aaacttcttgaagaagcctttttacctgatttacgagctgccactatgcttgataggaac gatggttacgaatcagatatggctttagcaatgaatcgttacataggaaatagtatttta ccgttgctaattaaacactcgaaattttataacgaggcagataattattctagtttactt gatgcgacacttcacactgtttatcgtttaagtaaaaacagaatgttgaccaaaggacaa cgagaagcggtttcagatttcctggttgcattaacaagtcaaatgcaacccagtatgctg ctgaagcttcttcgaaaattgactgtcgatgtttctaatttatcggaatatacaacagta gctttgaggctcttaacattacactatgatcgttgtggaaaatattatggatcaactgga tcgagtggttcgagtccttatggtgcttccagcgatgaagagaaaagattgacaatggtt cttttcagtaatatatttgattctctgtcaaaaatggactacgatccagaattattcgga aaggctcttccttgcttaacggccattggatgtgctctaccaccagattattctttatct aaaaattgcgacgacgaatggtatggaagcaaatcggcttctactcaatctaccgatggt ccctataatcctcaaccaatcaacacttctagtgtggtgctgaataatgatttgaatcaa atagttcaaaagttttccgaacactatcatgatgcctgggcaagtcgaaaattagaaaat ggttggacttttggagattcctggtcagatgcgaataaaacacatccgagattaaagccc tataatacgttgaatgattatgaacgagaaagatataaggaaccggttcgagaaagtttg aaagcacttttagcaattggttggagtgttgaacacgcggaggttgataataaatcaacg aatcgtaattctttgagacgatcctccaaaagtcagggtgattctgcaagtccattcaac tataatcctcatcctgttgatatgacaaatttgacattaagtagagaaatgcaaaatatg gctgaaagattagcggacaatgctcacgatatttgggccaagaaaaagaaagaagaactt cttactgtcggtggtggaatacatcctcaactagtgccctacgatcttttgacagacaaa gaaaaacgaaaagatcgtgaacgttctcaagaatttttgaaatatctccaatatcaggga tacaaacttcacaaaccaaatcgtggaggagaagcggaagttggaggagttggagcggca gtagaattaagattcgcctattctctgcttgagaaattgatagaatatcttgataaagca actattaatatgaaacttttaagaccatcggacaccttcagtagaagaacaagtttcaaa actgctaccagggatattaaatttttcagcaaggtagttttgccacttgtggaaaaatat tttagcactcatagaaattattttatagccgttgcaacagctaccaataatgttggtgct gcatctctcaaagagaaggaaatggtagctgccttattttgcaaattggcaagtttactc agatcaagaatggctgcctttggagcagacgtaagaattaccgtcaggtgccttcaagtt ttagttaagggtattgatgccaaatcactagtgaagaactgtccagaatttattcgaact tccatgttgactttcttcaacaacactgctgatgatcttggtcatattattctcaactta caagagggcaaattcagtcatcttagagggactcatttaaaaacatccacatcgctctcg tatattaacagtgtcattcttccagtactcacagccatgtttgatcatcttgcaacttgt gaatatggcagtgatcttctattggacgaaattcaagtagcttcctataaaatgttggcc tcactctacaccctcggtgtggattccactttgactcaagatcgaaaatacctaaaaaca gaaatcgagagaagtaaaccaaatttaggttcatgtttaggagccttctccagctgtttt ccagtggcttttctcgaaccacatttaaataaacataatcaattctccctgttaaatcga atagctgatcattcactagaagctcaggatgtaatgacaagaatggaatcaagtatgcca acattggaaacaattttatcagaagtggatcaatttgttgaatctgaaaaaacttacact gatgcaccgcacgttgttgatgtgattcttccacttctttgctcgtatcttccattgtgg tgggctcaaggtccggataatgtgaatccaacggaaggcgcatacgtcagtatggtgaca agtgatcacatgaatcaacttttgaaaaatgttctcaaattgattaaaaagaacattgga aatgagaatgcaccatggatgacgagaattgcggcttacacacagcaaattattatcaat tcttcggaagaattactcaaggatccattcctacctttggcggaacgtgtgagaaaacgt actgacaatatgtttcacaaagaagaatcacttagaggatttattaaatcatccaccgat gatacttcacaagttgaggcacaaatacaagaagattggcaattattggttcgtgatatc tattcattttatccacttctcatcaaatatgtcgatcttcaacgtaatcaatggctgagg aataatatttcggaagcggaggatctttataatcacgttgcgtcgatatttaacatttgg tcgaaatcgcagtactttttacgagaggaacagaattttatatctgcgaatgaaattgat aatatggttcttattatgcctactgcgacgaggagaccagcggctgtgagtgaaggagcg actcccgctggaggtggaaagaaaaagaagaaacatcgggataagaaacgagacaaggac aaggaagttcaagcatcactgatggtagcatgtttgaagaggcttctgccagtgggattg aatttatttgcaggacgtgaacaagaattggttcagcattgcaaggatagatttttgaaa aaaatggccgagcatgaaattacggaatttgcaaaaactcaattgaccctaccggataaa attgatccagctgatgaaatgtcttggcagcattatttatattcacaacttggtcaaaaa aaggatgttatggaaccagtgaaagctcaacaaatcgacgatgttgttgctagaataaca gatatggcgaaagttctttatggcttgcatatgatcgaccatccgcaacagcaaagcaaa agtcaatatcgatcagtggtttcaattcagagaaagcgagccgtcattgcttgttttcgt cagatctcccttcactccctgcccaggcatcgggctataaatatttttgcccgaacatat tatgaattatggcttcaggatgaaaatgttggccaggaagttatgattgaagatcttacg caatcgttcgaagatgcagaattgaacaaaacggatggtaaagaagatgaaggtaaaccg gatccactgacacaattagtgacaacattctgtcgaggagcaatgactgaaagatctgga gcacttcaggaagatcctctttatatgagttacgcgcaaattatatcgaaatcctgtggc gaagaagaggaagaagaagaaggtgaaggtggtggcgaagaagaaggacgtgcttcaatt cataggccaatgcataaattaatggaacaagaaatggaaaaacaaaaattattatttcat caagcgcgacttgcaaatcgcggagttgcggaaatggttcttcttcacatatcagcttgc aaaggtgttcctagtgagatggtgatgaaaactctcgaattgggaatctctattcttcgt ggtggtaacattgaaattcaaaaaggaatgttgaatcatctgaaggaaaaaaaagacgtt ggtttcttcacatcaattgcgggattaatgaattcgtgcagtgttttggatttagatgct tttgagagaaataccaaggcagaaggtcttggtgttggatcagatggagctgctggtgaa aaaaatatgcacgatgctgaatttacttgtgcattattcagatttattcaattgacctgt gagggtcacaatcttgactggcagaattatttaagaactcaagcgggtaatacgacaacg gtaaatgttgtaatttgtaccgtcgattatttattacgattacaagaatcaattatggac ttttattggcattattcgagtagagaattgattgatcctgcgggtaaagcaaattttttc aaagctattggagttgcgagtcaagtttttaatacacttacggaagtaattcagggacct tgtgcacaaaatcaacaagcacttgctcattcgagattgtgggatgctgtgggtggattt ttatttttattctcacatatgcaggataaattatcgaaacactcgagccaagtggattta ttgaaggagttgcttaatcttcagaaagatatgatcacaatgatgctgtccatgttggaa ggtaatgttgtaaacggaacgattggaaagcagatggtcgatactttagtggaatctgcc agcaatgttgaacttattctcaaatattttgatatgttcctgaaactgaaagatcttgtt tcttcacccagtttcttagaagtggatttaaacagtgatggatgggtttatcctaaagat ttcaaagaaaaaatggagcagcaaaagagttacactgacgaggaaattgaatttcttctc gcctgctgtgaaacgaatcacgatggaaaaatcgactatgtcgcattcatggatcgtttt cacgagccagctaaggagattggttttaatctggcagtacttttaacaaatctttcggag catatgccaaatgaacccaggttagcgagattcctcgaaacagccggttctgttcttaat tatttcgagccattccttggccgtatagaaattcttggaagtaataaaaagatcgagagg gtctattttgagattaaggaatcaaatattgagcagtgggagaagccacagattaaggaa tcaaaacgtagttacttttacaatactgtcgttgaggctggcgataaagagaaattggag 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cgaatcatgttcgacattactttcttcttctttgtcattattattttactcgctattatc caaggtttgatcatcgatgcctttggagaacttcgagaccaactcgaaagtgtgaaagcc aacatggaaagtaattgtttcatttgtggcttaggaaaagaatattttgataccgttcct catggatttgatacacacgttcaacaggaacataatcttgccaattacatgttctttttg atgcacttaatcaacaaacctgataccgaatacactggtcaggaaacttatgtatggaat ttgtaccaacaaagaagttgggacttcttcccagttggagactgtttcagaaaacagaat gacgccgtcgaagaagaagcgaagaagaaataa

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