Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365: LBUL_0312
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Entry
LBUL_0312 CDS
T00419
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
lbu
Lactobacillus delbrueckii subsp. bulgaricus ATCC BAA-365
Pathway
lbu00300
Lysine biosynthesis
lbu00550
Peptidoglycan biosynthesis
lbu01100
Metabolic pathways
lbu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lbu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LBUL_0312
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LBUL_0312
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LBUL_0312
Enzymes [BR:
lbu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LBUL_0312
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ABJ57974
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Position
299675..301042
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AA seq
455 aa
AA seq
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MKMQLAEIAQALNTSCEGDAETVITSVAFDSRKISQGALFIPIKGERDGHDFVGSAIEAG
ASATLWEAGNPNKPEGIAVLEVADTLKAMQDLARYYLQKVNPTVVSITGSNGKTTTKDMV
AAVLAKRFNVYKTQANFNNEIGVPMTILEMKPITEILVLEMGMDRAGQLHELSQLARPDV
AVITMIGEAHIEFFGSRDKIADAKMEITDFLQEDGEFIYNGDEPLLAERAAKLPQDKSTF
GFADSDSIHASDLRSTMHHSFFKINGTDREFSIPMIGRHNVANAMAAILVGRHFGESDEE
IAAGLANFVPTANRMEWEKGDCGEDIMSDIYNSNPTAVKAVTASFGQVPVSEDGRRIAVL
ADMLELGSRSADLHKGLAACLDPDKINVLYLYGPEMNHLYQALLDKYGQQNLHYYPEDEM
SHLIDDLKSDIHSQDIVLLKGSHGMHLERVLDRLK
NT seq
1368 nt
NT seq
+upstream
nt +downstream
nt
atgaaaatgcagttggcagaaatcgcccaagccttaaataccagttgtgaaggggacgca
gaaacggtcattacctcagtggcctttgactcaagaaagatcagccagggcgccctcttt
atcccgatcaagggggaaagagacggccacgattttgtgggttcagccattgaagccggc
gccagcgccactttgtgggaagctggcaacccaaacaagccggaaggcatcgcggtttta
gaagttgccgacaccttgaaggccatgcaggatctggcccgctactacctgcagaaggtc
aacccaaccgtggtcagcatcaccggctcaaacggcaagaccacgaccaaggacatggtg
gcggcggttttggccaagcgcttcaacgtttacaagacccaggccaacttcaacaatgaa
atcggcgtgccgatgaccattttggaaatgaagccgatcactgaaatcctggttttggaa
atggggatggaccgagctggccaactgcatgaactgagccagctggcccggccggatgtg
gcggtcatcaccatgatcggggaagcccatatcgaattcttcggcagccgggacaagatc
gccgacgccaagatggaaatcacggactttttgcaagaagacggcgaatttatctacaac
ggtgatgaacccctcctggcggaaagagccgcaaagcttccccaggacaagtccaccttc
ggtttcgcggactctgacagcattcatgccagtgacctccgcagcaccatgcaccattcc
ttcttcaagattaacgggactgaccgggaattctcaattccaatgatcggccgccacaat
gtggctaacgccatggccgctattctggttggccgccacttcggggaaagcgacgaggaa
atcgccgctggcctggccaacttcgtgccaacggccaaccggatggaatgggaaaagggt
gactgcggtgaagacatcatgagcgatatctacaactccaacccaacggcagttaaggcc
gtgactgcctcctttggccaggttccagtcagtgaagacggccgccggatcgcggttttg
gccgacatgctggaactgggcagccggtcagccgacctgcacaagggtctggctgcctgc
ctggacccggacaagatcaacgtcctttacctttacgggccggagatgaaccacctttac
caggccctgctggacaagtacggccagcagaatctgcactactacccagaagacgagatg
agccatttaatcgatgatttaaagagcgacatccacagccaggacatcgttttgctgaag
gggtcccacgggatgcacctggaacgagtcctcgacagactgaaatag
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