Lachnospiraceae bacterium KM106-2: lbkm_3240
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Entry
lbkm_3240 CDS
T08927
Name
(GenBank) D-alanine--D-alanine ligase
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
lbx
Lachnospiraceae bacterium KM106-2
Pathway
lbx00470
D-Amino acid metabolism
lbx00550
Peptidoglycan biosynthesis
lbx01100
Metabolic pathways
lbx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
lbx00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
lbkm_3240
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
lbkm_3240
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
lbkm_3240
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
lbx01011
]
lbkm_3240
Enzymes [BR:
lbx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
lbkm_3240
Peptidoglycan biosynthesis and degradation proteins [BR:
lbx01011
]
Precursor biosynthesis
Amino acid ligase
lbkm_3240
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Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp
GARS_A
ATP-grasp_4
Motif
Other DBs
NCBI-ProteinID:
BBF44527
LinkDB
All DBs
Position
complement(3407847..3408908)
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AA seq
353 aa
AA seq
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MSKLTVAVLFGGQSSEHEVSLVSAATIISNINTEIYNVLMIGITKDGKWLKVDSVEDIKN
GNWLKGKVTAVISPDTGHKGVLLLENDKATVQKVDVIFPALHGLYGEDGTVQGLIELSRI
PYVGCGVLASAVSMDKLYTKIIVDTLGIRQAQYVGIFKDQLSDMDEVVARVEAKLDYPVF
IKPSNAGSSKGVSKAHDRKELVVGLEEAAKHDRKILVEETIIGREVECAVLGGNEVKASG
VGEVIAAADFYDYEAKYNNAESKTDIQPDLPEGTEQEIREDALKIFKAVDGFGLARIDFF
LEKGTNQVVFNELNTLPGFTAISMYPMLWEVKGISKSRLVEKLIQLALVRYQG
NT seq
1062 nt
NT seq
+upstream
nt +downstream
nt
atgagtaaattgacagtagcagttttgtttggtgggcaatcttcagaacatgaggtttct
ttagtctcagcagcaactattatttcaaatataaatacagagatttataacgtcttaatg
attggtattacgaaggacggaaaatggttaaaggttgatagtgtagaggatattaaaaat
ggtaattggttaaaggggaaagtaacagcagttatctctcctgatactggtcataagggt
gttcttttattagaaaatgataaagcaaccgtacaaaaggtagatgtaatcttccctgct
ttacatggcttatatggcgaagatggaacagtacaaggattgattgaattatctagaatc
ccatatgtaggatgtggtgttttagcttctgctgtttctatggataagttatatacaaaa
attatcgtagatacattaggaatccgtcaggctcaatatgttggaatcttcaaagatcaa
ttatctgatatggatgaagtagttgccagagttgaagctaagttagactatccagtattt
attaaaccatccaatgcaggaagttcaaagggtgtttctaaagcacatgatcgtaaagaa
ttagtagttggtttagaagaagcagcaaaacatgatagaaagattcttgttgaagaaaca
attatcggaagagaagtagaatgtgctgtattaggtggcaatgaagtgaaagcttctggc
gttggtgaagttatcgcagcagcagatttctatgattatgaagctaaatacaacaatgca
gaatctaagacagatattcagccagatctaccagaaggaacggaacaagaaattcgtgaa
gatgctcttaagatctttaaggcagttgatggttttggtttagctcgtatcgacttcttc
cttgaaaaaggaacaaatcaggttgtatttaatgaattaaatacattaccaggtttcaca
gcaatcagtatgtacccaatgttatgggaagtaaaaggaattagtaaatcaagattagtt
gaaaagttaattcagctagcacttgttagataccaaggataa
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