Leishmania braziliensis: LBRM_20_3020
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Entry
LBRM_20_3020 CDS
T01113
Name
(RefSeq) DNA topoisomerase IB, large subunit
KO
K03163
DNA topoisomerase I [EC:
5.6.2.1
]
Organism
lbz
Leishmania braziliensis
Brite
KEGG Orthology (KO) [BR:
lbz00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lbz03032
]
LBRM_20_3020
Enzymes [BR:
lbz01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
LBRM_20_3020
DNA replication proteins [BR:
lbz03032
]
Eukaryotic type
DNA Topoisomerases
LBRM_20_3020
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_I
Topoisom_I_N
DUF3891
Motif
Other DBs
NCBI-GeneID:
5415133
NCBI-ProteinID:
XP_001564582
UniProt:
A4HB62
A0A3P3Z536
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All DBs
Position
20_and_34a:1225595..1227508
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AA seq
637 aa
AA seq
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MKVEDRKMAVKREQSHSNEDEENNEEDLNWWEQENLRIAMKGERRWETLSHNGVLFPPEY
EPHGISIFYDGREFKMTPEEEEVATMFAVMKEHDYYRMEAFRRNFFESWREILDKRQHPI
RRLELCDFEPIYQWYLAEREKKLNRTKEEKKSIKEKQDMDAEPYRYCMWDGRREQVANFR
VEPPGLFRGRGKHPLMGKLKARVQPEGITINIGETAEVPVPPAGHKWGAVQHDHTVTWLA
MWRDSVVGNAKYVMLAASSSVKGQSDMMKFEKARKLKDKVDDIRASYMEDFKSNDVHVAQ
RAVAMYFIDRLALRVGNEKGEDEADTVGCCSLRVEHIQLMSDNIVRFDFLGKDSIRYQND
VAVLPEVYALLQRFTRRKSPGTDIFDQLNPTQLNDHLKSFMNGLSAKVFRTYNASITLDR
WFKEKPVDSKWSIADKLAYFNKANTEVAILCNHQKAISKNFKLQMMQLTTKSEYTRKMIE
LLEKAEVTAKKKSVEEAAKEFLEEQDRMQREWLASYGTEEQKKEFEEIVAKRTALCVRSG
KKTSSSGTKKAKSASRKKKAGKKKTKAAKKSSKGSSKKASSKSSKKTPKKSKQEDEDDMP
LTIMAAKTKKTAGVKRHRAAKEAASDDDDVPLAALRV
NT seq
1914 nt
NT seq
+upstream
nt +downstream
nt
atgaaggtagaagatagaaaaatggcggtgaagcgagagcagagccactccaatgaggat
gaggaaaacaacgaggaggacctgaactggtgggagcaggaaaacctccgtattgccatg
aagggtgagcgtcgctgggagacgctgagccataacggggtcctttttccgcccgagtac
gagccccacggtatctccatcttctacgatggacgcgagttcaagatgacgccggaggag
gaggaggtggcgacaatgtttgccgtgatgaaggagcacgactactaccgcatggaggcg
ttccggcgcaacttcttcgaaagctggcgcgagattctggacaagcggcagcaccccatc
cgtcgcctggaactgtgcgacttcgagcccatctatcagtggtacctcgccgagcgggaa
aagaagctcaaccggacgaaagaagagaagaaatccatcaaggagaagcaggacatggat
gctgagccgtaccgctactgcatgtgggacggacgtcgcgagcaggtggcgaatttccgc
gttgagccaccgggcctgtttcgtgggcgcggcaagcacccgctgatgggcaaactgaag
gcgcgcgtgcagccggagggcattacaatcaatattggcgagacagccgaggtgccggtg
ccacctgcaggacacaaatggggtgctgtgcagcacgaccataccgtgacatggcttgcc
atgtggcgtgacagcgtggttggtaacgcaaagtacgtgatgctcgccgcgtcttccagc
gtcaagggacagtctgacatgatgaagtttgagaaggcgcgcaagctcaaggacaaagtg
gatgacattcgagcatcctacatggaggacttcaagtctaacgatgtgcacgtggcgcag
cgggctgtcgccatgtacttcattgaccgtcttgccctccgtgtgggtaatgagaagggc
gaggatgaggcggacacggtgggttgctgctcgctgcgtgtggaacacattcagctgatg
tcggacaacatcgtgcggttcgactttctgggtaaggactcgatccgttaccagaacgac
gtcgccgttctcccagaggtgtacgcgctgctgcagcgctttactcgtcgtaagtcgccg
ggcacggacatctttgatcaactcaacccgacgcagctgaacgatcacctcaagtccttc
atgaacggcctctctgccaaggtgttccgtacctacaatgcctccatcaccctcgatagg
tggttcaaggaaaaacctgtcgactctaagtggtctatcgcggacaagctggcctacttc
aacaaggctaataccgaggtggcgattttgtgcaaccatcaaaaagccatctcgaagaac
ttcaagctgcagatgatgcagctgaccaccaagtctgagtacactcgcaagatgattgag
ctactggagaaggcggaggtgactgccaagaaaaagtcggtcgaggaggccgcaaaagag
tttctggaagagcaggaccgcatgcagcgtgagtggcttgcgagctacggcacggaggag
cagaagaaggagtttgaggaaatcgtggcgaagcgtacggcactgtgcgtgcgctctggc
aagaagacatcctcatcgggcaccaagaaggccaagtctgcatctcgcaagaagaaggct
ggtaagaagaagacgaaggctgccaagaagagttcgaagggttcgagcaagaaggcaagc
agtaagtcgtctaagaagacgccaaagaagtcgaagcaggaagacgaggacgatatgccg
ctcacgattatggcagccaagacgaagaagacagctggtgtcaagcggcaccgcgccgcc
aaggaggcggccagcgacgacgatgacgtgcctctcgcagctctgagggtgtag
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