KEGG   Leishmania braziliensis: LBRM_35_1780
Entry
LBRM_35_1780      CDS       T01113                                 
Name
(RefSeq) putative clathrin heavy chain
  KO
K04646  clathrin heavy chain
Organism
lbz  Leishmania braziliensis
Pathway
lbz04142  Lysosome
lbz04144  Endocytosis
lbz05100  Bacterial invasion of epithelial cells
Brite
KEGG Orthology (KO) [BR:lbz00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    LBRM_35_1780
   04142 Lysosome
    LBRM_35_1780
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05100 Bacterial invasion of epithelial cells
    LBRM_35_1780
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lbz04131]
    LBRM_35_1780
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lbz04147]
    LBRM_35_1780
Membrane trafficking [BR:lbz04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Clathrin
    LBRM_35_1780
Exosome [BR:lbz04147]
 Exosomal proteins
  Proteins found in most exosomes
   LBRM_35_1780
SSDB
Motif
Pfam: Clathrin Clathrin_H_link Clathrin-link Clathrin_propel ACDC TPR_COPA_B Erf4
Other DBs
NCBI-GeneID: 5419773
NCBI-ProteinID: XP_001568798
UniProt: A4HP23 A0A3P3ZIG8
LinkDB
Position
36:complement(651780..656864)
AA seq 1694 aa
MNSPSLSLEVFQLNSVSGGLRPGSIAFKNVTVESEKYVCVRDVQEDGQTSLVIVDIEKRE
SIRNNVKDAESCIMNPRSKILALRSGRNLQVFDVEASRRLKATLFHDDVVHWGWIDDRTL
GIVTGKAVYHWSLDGAADDAPLHIFDRSADYDSSVQVLSYRSDEQKKWLLVTGVARDPSG
AMVGKALLYSVENRSSRVLDGHACCFISTPTPSESRKCNVMCLAWNSPQQGGQVMIMELP
TGSKTDLSLPRRIYNLRIQPGDFPVAMHVSDRHKLLTVVTSRGTFALMDIFTGVIVAEQQ
FTPAVVFRGAGDNKVGGVVCVNNQGSVMRIGPNDSGIINYIKNNMQNPELALRIASTANL
GGVDDLFKVQLDNYLRIGNIEEATRICLRAPGNMLRTREILMNFMQMPQQPGQPPAISTY
FKIVLAETSLNEYESVELARAVVPKGGIGYVKQQFDEGKLTASEELGDMVQQADPNMALK
IFHQGNVHAKVLNVLLQRNETQKAVEYCKRSNFSPDWRVIVNNFIRVAPQDAVNLCLMLY
REMGDKPVLSAEEMMDMFVSAQQIQQATEFLLEVLRDHNDESTMDLQTKLLEINLKYSHP
SVADKIFVRNICQYYDGMKLAPLCERVGLHQHAIECYMIAQKQDPNLNNLSSIRRCLKQL
QSFNPEWLVEFFGKLNKQESLKCLEDLCTNSRQSFKVLVQVATKYSDALGSTDLIGMFLE
HNLYDVLYYYLGAVVPYTRDAEVHFRYIEAAAEMGQMQELERMTRESPCYDAERTKNYLK
SKKLTDLWPFINVCDQHNMVNEMVHYLVETSNENYIEQYVTRRSPGKTPQVVQALIECNV
SEDFITNMLSVVGTMCPSEELVQCVEETGRLHLIKQWLEDRRSEKKTDKALYNALAKIYV
DIGQSPEQFLAENEYYDALVVGRYCETRDPNLAYIAYSHDHCSKELVDLCYRNGMYKQLA
RYLVKEQDLDLWTSVLAEDTAHRQQLVESVQQTALPESVVSEEVSTTVRAFMNANLTEEL
TALLSQIVVHGRFRKNRFLENLLIMSAVRSRKDKVMEYVTTLEDYDGADIAHLASGAGMH
EVAFVVYTRHNMQKEAIKVLLQDMNDVSRGRAFAQKTDTAAVWSVLGEYLVKQDEVHEGI
ECLIKAKNPDLVVEVTSAAERTNQYSDLIKYLSMARQYSRAKDSKIDTALVITYAKTGRL
GELEEFLKQAHNVKIGAIADKCFDEKLYESARVLYTVANNYARLASTEVMLSNLPNAVEA
AKKAKSIHTYKEVNLACIEAGDMKLASICAVPVVLKAEEVSGMYNRYESRGMWEELFSVL
KIASSHQGAHMSIFTEMGVLLAKYRPEKLIEHVNMYSKKINTHKMITVCEQYHHWIVLRL
LHINNEDWLAAANLMMHRHADTFDNEIFKEVISHLGASDVVYTAIGFYLRTHPEHLNDFL
SSIFKRVDPERVMEETMRVTPIYVIRAFLETAQERNIKKVNEALNDLYIEEEDFKTLRHS
VETYNNFDSEELSSRLEKMELFEFRKIAMLLHRKNKRYAHAIAAAKENKLFDEAIDTAAE
SADGELVTSLLDYFVKDYPDCFVACLYRCYDLLKPSAVLLKAWLNHRTEVAMPYMIQVLQ
EYSSKIDRMEKSMVDAQVAAKDAARRAGPMQGPSAAPLMIEQGDGMVMNGMPMSRPQPPM
SFGAPPQFGSGRPF
NT seq 5085 nt   +upstreamnt  +downstreamnt
atgaactctccctcactttctttggaggtctttcaacttaactccgtctcgggtggcctc
cgcccgggttccatcgccttcaaaaatgtcacggtagagagcgagaaatatgtctgcgtc
cgcgatgtgcaggaggacgggcagacatcactcgtcatcgttgatatcgagaagcgtgag
agcattcgaaacaacgtcaaggatgcggagtcgtgtattatgaaccccaggtcgaaaatc
ctggcgctccgcagtggtcgcaacctgcaggtgttcgacgtggaggcctcgcgacgtctc
aaggcgacgcttttccacgacgacgtcgtccactggggctggattgacgaccgtactctg
ggcattgtgacggggaaggccgtctaccactggagcctcgatggcgccgccgacgacgcg
ccgctgcacatcttcgaccgcagcgcggactacgacagctccgtgcaggtgctctcgtac
cgcagcgacgagcagaagaagtggcttctcgtgacaggtgtagcccgcgacccatcgggt
gctatggtgggcaaggcgttgctgtacagcgttgagaaccgcagcagtcgtgtgcttgac
ggtcatgcgtgctgcttcatctccacccccaccccgtccgaatctcgcaagtgtaacgtg
atgtgccttgcctggaacagtccgcagcagggcggccaggtcatgatcatggagttgccg
accggctccaagacagatttgtcgttgccacggcggatttacaacctgcgcattcaaccc
ggcgacttcccagtcgccatgcacgtctcggaccgccacaagttgttgaccgtggtgacg
agccgtggcacctttgcgttgatggacatctttaccggagtcatcgtggccgaacagcag
ttcacgccggcagtagtgttccgtggcgcaggcgacaacaaggttggcggtgtcgtgtgc
gtcaacaaccagggctccgttatgcgcatcggcccgaacgacagcggcatcatcaactat
attaagaacaacatgcaaaaccctgagctggctctgcgcatcgcctccacggcgaacctc
gggggtgtcgatgacctcttcaaagtgcagctggacaactacctgcgcattggcaacatc
gaggaggccacccggatatgcttgcgcgccccggggaacatgctgcgcacccgtgagatt
ctcatgaatttcatgcaaatgccgcagcagccgggccagccgccggctatctcgacctac
ttcaagattgtgctggcggagacgagcctgaacgagtacgagtctgtcgaacttgcgcgc
gcggtggtacccaagggtggcattggctacgtgaagcagcagtttgacgagggaaagctg
acggcctcggaggagctcggcgacatggttcagcaggcggaccccaacatggcgctgaag
attttccaccagggcaacgtccacgccaaggtgctcaacgtgctgctgcagcgcaacgaa
acgcagaaggcggttgagtattgcaagcgatccaacttctcgccggattggcgcgtcatc
gtgaacaacttcatccgggttgcgccacaggacgccgtcaatctttgcctgatgctctac
cgagagatgggcgacaagccggtgctcagcgcggaggagatgatggacatgttcgtgtcg
gcccagcaaattcaacaggcgaccgagttccttctggaggttctgcgcgatcacaacgac
gaatcgacgatggacctgcaaacgaagctgctggagataaacctcaagtactcgcacccg
tccgtcgccgacaagatcttcgtccggaatatttgccagtactacgacggcatgaagctc
gccccgctctgcgagcgggtcggtctgcaccagcacgcgattgagtgctatatgattgct
cagaaacaggaccccaacctcaacaacctctcgagcatccgccgctgcctaaaacagttg
cagagctttaaccctgagtggctcgtcgagttcttcggtaagctcaacaagcaggaaagc
ctcaagtgcctcgaggacctctgcaccaactcgcgccagagcttcaaggtacttgtgcag
gtggccactaagtacagtgacgctctcggctccaccgacctcattggcatgttccttgag
cacaacctgtacgacgtgctctactactatctcggggccgtggtaccgtacacgcgtgat
gccgaggtgcacttccgctacatcgaggctgctgctgagatgggtcaaatgcaggagctg
gagcgcatgacgcgcgagagcccgtgctacgacgccgagcggacgaagaattacctcaag
agcaagaagctgacggacctgtggcccttcatcaacgtctgtgatcagcacaacatggtg
aacgagatggtgcactaccttgtggagacgagcaacgagaactacatcgagcaatacgtg
acgcgccgcagccctggtaagacgccacaggtagtgcaggccctcatcgagtgcaacgtg
agcgaggactttatcacgaacatgctctcagtggtggggacaatgtgccccagtgaggag
ctcgtgcagtgtgtggaggagacgggtcggctacacctcatcaagcagtggctcgaggac
cgtcgcagcgagaagaagacggacaaggcactgtacaatgcgctggccaagatctacgtt
gacattggccagagccccgagcaattcctggcggagaacgagtactacgatgcgttggtg
gtgggtaggtactgtgagacgcgcgaccccaacttggcctatattgcctatagccacgat
cactgcagcaaggagctggtcgacctctgctatcgcaacggcatgtacaagcaactggcc
cgctacctagtgaaggagcaggatcttgacctgtggacgagcgtgctggcagaggacacg
gctcaccggcagcagcttgtagaatcggtgcagcagactgccctgccagagagtgtggtg
agcgaggaggtgagcacgacggtgcgcgccttcatgaacgccaacctgacggaggagctg
accgcgctgctaagccagattgtggtgcacggccgcttccgcaagaaccgcttcctcgag
aaccttcttatcatgtctgcggtgcgttcccgcaaagataaggtgatggagtacgtgacg
acgctggaggactacgacggcgccgacattgcacacctcgcttccggcgccggcatgcat
gaggtggcgtttgtcgtatacacgcgtcacaacatgcagaaggaggccatcaaggtgctt
ttgcaggatatgaacgatgtttcgcgcggccgagcctttgcacagaagacggacactgcc
gctgtgtggtcggtgttgggcgagtacctggtgaagcaggatgaggtgcacgagggtatc
gagtgcctcatcaaggccaagaatcccgacctcgttgtcgaagtgacctctgctgcggag
cgcacgaatcaatacagtgatctcatcaaatacctctcgatggcacgccagtactcacgc
gcaaaggacagcaagatcgacacggcgcttgtcattacgtatgccaagacaggccgcctc
ggggagttggaggagttcctcaagcaggcgcacaacgtcaagattggcgccattgctgac
aagtgcttcgacgagaagctgtacgagtccgcgcgcgtgctgtataccgtggcgaacaac
tacgcccgcctggcgtccacggaagtgatgctgagcaacctgccgaatgccgtcgaggcg
gccaagaaggccaagtcgatccacacatataaggaggtcaatctggcgtgcattgaggct
ggagacatgaagctggctagcatctgcgccgtcccggtggtgctcaaggcagaggaggtc
agcggcatgtacaaccgctacgaaagccgcggcatgtgggaggaacttttctcggtgctc
aagattgcctctagtcatcagggcgcgcacatgtctatcttcaccgaaatgggcgttttg
ctggccaagtataggcccgagaagctcatagagcacgtgaacatgtactcaaagaagatc
aatacccacaagatgatcactgtctgcgagcagtaccatcactggatcgtgctgcgtctt
ctgcacatcaacaacgaggactggctggccgcggccaacttgatgatgcatcgccacgcg
gacaccttcgacaacgagatcttcaaggaagttattagccacctcggcgccagcgatgtc
gtgtacacggcgattggcttctacctcaggacacaccctgagcacctgaacgacttcctg
tcctccatcttcaagcgcgtggacccggagcgagtgatggaggagacgatgagggtgaca
ccgatctacgtgattcgagcctttctcgagaccgcgcaggagcgcaacatcaagaaggtg
aatgaggctctcaacgacctctacatcgaggaggaagacttcaagacgctgcgccactcc
gttgagacgtataacaacttcgactcggaggagctgtcgtcacggctagaaaagatggaa
ctctttgagtttcgtaagattgccatgctgctgcatcgcaagaacaagcgctacgcgcac
gccattgcagccgcaaaggagaacaagctcttcgacgaggccatcgacacggcggccgag
agtgctgacggcgagctggtgaccagcctgctcgactacttcgtgaaggactatcccgat
tgctttgtggcgtgtctctacaggtgctacgacctgctgaagccctcggcggtgttgttg
aaggcgtggctgaatcatcgaactgaggtagcaatgccgtacatgattcaggtgcttcaa
gaatactcgagcaagatcgataggatggagaagtcgatggtggacgcgcaggttgcggcg
aaagatgcggctcgtcgtgccggcccaatgcagggtcccagcgccgcgccactcatgatc
gagcagggtgacggcatggtgatgaacgggatgccaatgagtaggccccagccgccgatg
agctttggcgcgccgcctcagttcggatctgggcggcccttctag

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