Lemur catta (Ring-tailed lemur): 123620372
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Entry
123620372 CDS
T08326
Symbol
ACACA
Name
(RefSeq) acetyl-CoA carboxylase 1 isoform X1
KO
K11262
acetyl-CoA carboxylase / biotin carboxylase 1 [EC:
6.4.1.2
6.3.4.14
2.1.3.15
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00061
Fatty acid biosynthesis
lcat00620
Pyruvate metabolism
lcat00640
Propanoate metabolism
lcat01100
Metabolic pathways
lcat01212
Fatty acid metabolism
lcat04152
AMPK signaling pathway
lcat04910
Insulin signaling pathway
lcat04922
Glucagon signaling pathway
lcat04936
Alcoholic liver disease
Module
lcat_M00082
Fatty acid biosynthesis, initiation
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
123620372 (ACACA)
00640 Propanoate metabolism
123620372 (ACACA)
09103 Lipid metabolism
00061 Fatty acid biosynthesis
123620372 (ACACA)
09110 Biosynthesis of other secondary metabolites
00254 Aflatoxin biosynthesis
123620372 (ACACA)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
123620372 (ACACA)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
123620372 (ACACA)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
123620372 (ACACA)
Enzymes [BR:
lcat01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.15 acetyl-CoA carboxytransferase
123620372 (ACACA)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.4 Other carbon-nitrogen ligases
6.3.4.14 biotin carboxylase
123620372 (ACACA)
6.4 Forming carbon-carbon bonds
6.4.1 Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
6.4.1.2 acetyl-CoA carboxylase
123620372 (ACACA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ACC_central
Carboxyl_trans
CPSase_L_D2
ACCA_BT
Biotin_carb_N
Biotin_carb_C
Biotin_lipoyl
ATP-grasp
Dala_Dala_lig_C
ATP-grasp_3
MetallophosN
Motif
Other DBs
NCBI-GeneID:
123620372
NCBI-ProteinID:
XP_045381507
LinkDB
All DBs
Position
15:24663299..24894630
Genome browser
AA seq
2288 aa
AA seq
DB search
MEGSLEENKEMRYYMLQRSSMSGLHLVKQGRDRKKIDSQRDFTVASPAEFVTRFGGNKVI
EKVLIANNGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVTPEDLKANAEYIKMADHYVPV
PGGPNNNNYANVELILDIAKRIPVQAVWAGWGHASENPKLPELLLKNGIAFMGPPSQAMW
ALGDKIASSIVAQTAGIPTLPWSGSGLRVDWQENDFSKRILNVPQELYEKGYVKDVDDGL
KAAEEVGYPVMIKASEGGGGKGIRKVNNADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHL
EVQILADQYGNAISLFGRDCSVQRRHQKIIEEAPAAIATPAVFEHMEQCAVKLAKMVGYV
SAGTVEYLYSQDGSFYFLELNPRLQVEHPCTEMVADVNLPAAQLQIAMGIPLYRIKDIRM
MYGVSPWGNTPIDFENSAHVPCPRGHVIAARITSENPDEGFKPSSGTVQELNFRSNKNVW
GYFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLIKLL
ETESFQLNRIDTGWLDRLIAEKVQAERPDTMLGVVCGALHVADVSLRNSISNFLHSLERG
QVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPNSYVVIMNGSCVEVDVHRLSDGGLLLSY
DGSSYTTYMKEEVDRYRITIGNKTCVFEKENDPSVMRSPSAGKLIQYIVEDGGHVFAGQC
YAEIEVMKMVMTLTAAESGCIHYVKRPGAALDPGCVIAKMQLDNPSKVQQAELHTGSLPR
IQSTALRGEKLHRVFHYILDNLVNIMNGYCLPDPFFSSRVKDWVERLMKTLRDPSLPLLE
LQDIMTSVSGRIPPNVEKSIKKEMAQYASNITSVLCQFPSQQIANILDSHAATLNRKSER
EVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLLRQYLRVETQFQNGHYDKCVFALREENK
SDMNTVLNYIFSHAQVTKKNLLVTMLIDQLCGRDPTFTDELLNILTELTQLSKTTNAKVA
LRARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCIENLQKLILSETSIFDVLPNFF
YHSNQVVRMAALEVYVRRAYIAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNRGNIPTLN
RMSFSSNLNHYGMTHVASVSDVLLDNSFTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFCD
SPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNVAIKTDCDIEDDRLAAMFREFTQQNKAT
LVEHGIRRLTFLVAQKDFRKQVNYEVDQRFHREFPKFFTFRARDKFEEDRIYRHLEPALA
FQLELNRMRNFDLTAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRAIIRHSDLVTKEAS
FEYLQNEGERLLLEAMDELEVAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEESVRSMVMR
YGSRLWKLRVLQAELKINIRLTPTGKAIPIRLFLTNESGYYLDISLYKEVTDSRTAQIMF
QAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGTTYIYDIPEMFRQSLIKLWESMST
QAFLPSPPLPSDILTYTELVLDDQGQLVHMNRLPGGNEVGMVAWKMTLKSPEYPEGRDII
VIGNDITYRIGSFGPQEDLLFLRASELARAEGIPRIYVAANSGARIGLAEEIRHMFHVAW
VDPEDPYKGYKYLYLTPQDYKRVSALNSVHCEHVEDEGESRYKITDIIGKEEGIGAENLR
GSGMIAGESSLAYDEIITISLVTCRAIGIGAYLVRLGQRTIQVENSHIILTGAGALNKVL
GREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEGVFTILHWLSYMPKSVHSSVPLLSSKDP
IDRIIEFVPTKAPYDPRWMLAGRPHPTHKGQWLSGFFDYGSFSEIMQPWAQTVVVGRARL
GGIPVGVVAVETRTVELSIPADPANLDSEAKIIQQAGQVWFPDSAFKTYQAIRDFNREGL
PLMVFANWRGFSGGMKDMYDQVLKFGAYIVDSLRECSQPVMVFIPPQAELRGGSWVVIDS
SINPRHMEMYADRESRASVLEPEGTVEIKFRRKDLVKTMRRVDPVYIHLAERLGTPELSL
AERKELENKLKEREEFLIPIYHQVAVQFADLHDTPGRLQEKGAINDILDWKTSRTFFYWR
LRRLLLEDLVKKKIHNANPELTDGQIQAMLRRWFVEVEGTVKAYVWDNNKDLVEWLEKQL
TEEDGVHSVIEENIKCISRDYVLKQIRSLVQANPEVAMDSIVHMTQHISPTQRAEVIRIL
STMDSPST
NT seq
6867 nt
NT seq
+upstream
nt +downstream
nt
atggagggttctctagaggaaaataaggagatgagatattacatgcttcaaaggtccagc
atgtctggtttgcacctagtaaagcaaggtcgagaccgaaaaaaaatcgactctcagaga
gatttcactgtggcttctccagcagaatttgttacgcgctttgggggaaataaagtgatt
gagaaggttcttattgctaacaatggcattgcagctgtgaaatgcatgcggtctattcgt
aggtggtcttatgaaatgtttcgaaatgagcgtgcaatccgattcgttgttatggtcaca
cctgaagaccttaaagccaatgcagaatacattaagatggcagatcactatgtgccagtt
cctggaggaccaaacaacaacaactatgcaaatgtggaattaattcttgatattgctaaa
aggatcccggtacaagcagtgtgggctggctggggtcatgcttctgaaaatcccaagctc
ccggaacttctcttgaaaaatggcattgcctttatgggtcctccaagccaggccatgtgg
gctttgggggataagattgcatcttctatagtggctcagactgctggtatcccaactctt
ccctggagtggtagtggtcttcgtgtggactggcaggaaaatgatttttcaaaacgtatc
ttaaatgttcctcaggaactatatgaaaaaggttatgtgaaagatgtggatgatgggctg
aaggcagcagaggaagttggatatccagtaatgatcaaggcctcagaaggaggaggaggg
aagggaatcagaaaagtcaataatgcagatgacttccctaaccttttcagacaggttcaa
gctgaagtccctggatctcctatatttgtgatgagactagccaaacaatctcgtcatctg
gaggtgcagatcctagcagatcagtatggcaatgccatctctctgtttggtcgtgactgc
tccgtacagcgcaggcatcagaagattattgaagaagcacctgctgctattgctactcca
gcagtatttgaacatatggaacagtgtgcggtgaaacttgccaaaatggttggttatgtg
agtgctgggactgtggaatacctgtacagccaggatggcagcttctactttctggaattg
aatcctcggctgcaggtggagcacccttgtacagagatggtggctgatgtcaatctccct
gcagcacaactccagattgccatggggatccctctatatagaatcaaagatatccgtatg
atgtatggggtatccccttggggcaacactcccattgattttgaaaattctgctcatgtt
ccttgcccaaggggccatgttattgctgctcggatcactagtgaaaatccagatgagggt
tttaagcccagctcaggaacagttcaggaactaaatttccgcagcaataagaacgtttgg
ggttatttcagtgttgctgctgcagggggacttcatgaatttgctgattctcagtttggt
cactgcttttcctggggagaaaacagagaggaagcgatttcaaatatggtggtggctttg
aaggagctatctattcggggtgactttcgaactacagttgaatacctgatcaagctatta
gagactgaaagctttcagttgaatagaattgacactggctggctggacagactgatagca
gaaaaagtacaggcagagcgacccgacaccatgttgggagttgtatgtggggctctccat
gtggcagatgttagtctgcggaatagcatctctaactttcttcactccttagagaggggt
caagtccttcctgctcatacgcttctgaatacagtagatgttgaacttatctatgaggga
gtgaaatatgtacttaaggttactcgacagtcccccaactcctatgtggtgatcatgaat
ggctcatgtgtagaagtagatgtacatcggctgagtgacggaggactgcttttgtcctat
gatggcagcagttacactacgtacatgaaggaggaagtagatagatatcgcatcacgatt
ggcaataaaacctgtgtgtttgagaaggaaaatgacccgtcggtgatgcgctcaccttct
gctgggaagttaatccagtacattgtggaggatggaggtcatgtgtttgctggccagtgc
tatgctgagattgaggtgatgaagatggtaatgaccttaacagctgcagagtctggctgt
atccattacgtcaagcggcctggagcagctcttgaccctggctgtgtaatagccaaaatg
cagctggacaaccccagcaaggttcagcaggctgagcttcacacgggtagtctgccacgg
atccagagcacggcactcagaggcgagaagctccatcgagtgttccactacatcttggat
aatctggtcaacataatgaatggatactgccttccagatcctttctttagcagcagggta
aaagactgggtggagcggttgatgaagaccctcagagatccctcccttcctctcctagaa
ttgcaagatatcatgaccagtgtctctggccgtatccctcccaatgtggagaagtctatc
aagaaggaaatggctcagtatgctagcaacatcacctcagtcctctgtcagtttcccagc
caacagattgccaacatcctagatagccatgcagctacactgaaccgcaaatctgaacgg
gaagtcttcttcatgaacactcagagcattgtacaactggtacagaggtaccgaagtggc
atccgaggccacatgaaggctgtggtgatggatctgctccggcagtatctgcgagtggag
acacaattccagaatggtcactatgacaaatgtgtgttcgcccttcgggaagagaacaaa
agtgacatgaacactgtactgaactacatcttctctcatgctcaagtcaccaagaagaat
cttctggtcacaatgcttattgatcagttgtgtggccgggaccctactttcactgatgag
ctactgaatatcctcactgagctaactcaactcagtaagaccaccaatgctaaagtggcg
cttcgagcacgccaggttcttattgcctcccatttgccatcatatgagcttcgccataac
caagtcgagtctatcttcctatcagctattgacatgtacggacatcagttttgcattgag
aacctacagaaactcatcctatctgaaacatctatttttgatgtcctaccaaacttcttc
tatcacagcaaccaggtagtgagaatggcagctctggaggtatatgttcgaagggcttat
attgcctatgaacttaacagtgtgcaacaccgccagcttaaggacaacacctgtgtggtg
gaattccagttcatgctgcccacatctcatccaaacagagggaacatccccacgctaaac
agaatgtccttctcctccaacctcaaccactatggcatgactcatgtagctagtgtcagc
gatgtgctgttggacaactcattcactccaccgtgtcagcggatgggcggaatggtctct
tttcggacttttgaggattttgtcaggatcttcgatgaagtgatgggctgcttctgtgat
tccccaccccagagccccacattccctgaggcaggtcacacgtctctatatgatgaagat
aaggtccccagggatgaaccaattcacattctgaatgtggctatcaagactgactgtgat
attgaggatgacagactggcagctatgttcagagagtttacccagcaaaataaagctacc
ctggttgagcacgggatccgacgccttactttcctggttgcacaaaaggatttcagaaaa
caggtcaactatgaggtggatcagagattccatagagaattccctaaatttttcacattc
cgagcaagagataagtttgaggaggatcgtatctatcgtcacctggagcctgctctggct
ttccagttagagctgaaccggatgagaaattttgacctcactgccattccgtgtgctaat
cacaagatgcacctgtatctcggggcagccaaagtagaagtgggcacagaagtgacagac
tacaggttctttgttcgtgcaatcatcagacattctgatctggtcaccaaggaagcttct
tttgaatatctacaaaatgaaggagagcgactccttctggaagccatggatgagttagaa
gttgcttttaacaatacaaatgtccgcactgactgtaaccacatcttcctcaactttgtg
cccacagtcatcatggacccatcaaagattgaggaatctgtgcggagcatggtaatgcgc
tatggaagtcggctgtggaaattacgcgtcctccaggcagaactgaaaatcaacattcgc
ctgacaccaactggaaaagcaattcctatccgcctcttcctgacaaacgagtctggctat
tacctggacatcagcctgtacaaggaagtgactgactccaggacagcacagatcatgttt
caggcatatggagacaaacagggaccactgcatggaatgttaatcaatactccatatgtg
accaaagacctgcttcaatcaaagaggttccaggcacagtccttagggacaacatacata
tatgatatcccagagatgtttcggcagtccctgatcaaactctgggagtccatgtccact
caagcattccttccatcacctcctctgccatctgacatactgacatatactgagctagta
ttggatgatcaaggtcagctggtacacatgaacaggcttccaggaggaaatgaggttggc
atggtagcttggaaaatgaccctgaaaagtcctgaatatccagaaggccgagatatcatt
gttattggcaacgacatcacataccgaattgggtcctttgggcctcaagaggatttgttg
tttctcagagcttcggaacttgccagggcagagggtattccacgcatttatgtagcagcc
aacagtggagcaagaattggactggcagaagaaattcgtcatatgtttcatgtggcctgg
gtagatcctgaggatccttataagggatacaagtatttatatctgacccctcaagattat
aagagagtcagtgctctcaactctgtccattgtgaacatgtggaggatgaaggagaatct
aggtacaagataacagatattattgggaaagaagagggcattggagcagagaaccttcga
ggttctggaatgattgctggagaatcctcattggcttacgatgagatcatcaccatcagc
ctggtgacatgccgggccattgggattggggcttaccttgtccgtctgggacagagaacc
atccaggttgagaattctcacataattctaacaggagctggggctctcaacaaagtcctc
gggcgggaggtgtacacctccaataaccagcttggaggcatccagatcatgcacaacaat
ggggtgacccactgcaccgtttgtgatgactttgaaggggttttcactatcctgcactgg
ctgtcctacatgcctaagagcgtgcacagttcagttcctcttctgagctccaaggatcct
atagatagaatcatcgagtttgttcccacaaaggccccatatgatcctcgatggatgctg
gcaggccgtcctcacccaacccataaaggtcagtggttgagtggattttttgactatggc
tctttctcggagattatgcagccctgggcacagactgtggtggttggtagggccaggcta
ggaggcatacctgtgggagtcgttgccgtagaaacccgaacagtagagctaagtatccca
gctgatcctgcaaacctggattctgaagccaagataatccagcaggcgggccaggtttgg
ttcccagactctgcgtttaagacctaccaggctatcagggacttcaaccgtgaagggctg
cctctgatggtctttgccaactggagaggcttctctggtgggatgaaagatatgtatgac
caagtgctgaagtttggtgcttacattgtggacagcttgcgggagtgctcccagcctgtg
atggttttcatccctccccaggccgagctacggggtggctcttgggttgtgattgactcc
agcatcaacccgcggcacatggagatgtacgctgaccgagaaagcagggcatcagttctg
gagccagaagggacagtagaaatcaaattccgcagaaaggatctagtgaaaaccatgcgt
cgggtggacccagtgtacatccacttggctgagcgattgggcaccccagagctaagccta
gctgagcggaaggaactggagaacaagttgaaggagcgggaggaattcctaattcccatt
taccatcaggtagctgtgcagtttgctgacttgcacgacacaccgggccggttgcaggag
aagggtgctattaatgacatcctggattggaaaacatcccgtaccttcttctactggcgg
ctaaggcggctgttgctggaggacctggtcaagaagaaaatccacaatgccaaccccgag
ctgactgatggccagatccaggccatgttaaggcgctggtttgtggaagtggaaggaaca
gtgaaggcctatgtgtgggacaataataaggatcttgtggaatggctggagaaacagctg
acagaggaagatggtgtccactcagtaatagaggaaaacatcaagtgcatcagcagagac
tacgtcctcaagcagatccgcagcttggtccaggccaacccagaggttgccatggattcc
atcgtccacatgacccagcacatctctcccactcagcgagcagaagtcatacggatcctc
tccacaatggattccccgtccacgtag
DBGET
integrated database retrieval system
