Lemur catta (Ring-tailed lemur): 123620870
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Entry
123620870 CDS
T08326
Symbol
TOP2A
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
123620870 (TOP2A)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
lcat03032
]
123620870 (TOP2A)
03036 Chromosome and associated proteins [BR:
lcat03036
]
123620870 (TOP2A)
Enzymes [BR:
lcat01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
123620870 (TOP2A)
DNA replication proteins [BR:
lcat03032
]
Eukaryotic type
DNA Topoisomerases
123620870 (TOP2A)
Chromosome and associated proteins [BR:
lcat03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
123620870 (TOP2A)
Centrosome formation proteins
Centriole proteins
123620870 (TOP2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
HATPase_c
Toprim
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
123620870
NCBI-ProteinID:
XP_045382396
LinkDB
All DBs
Position
15:complement(38125840..38161767)
Genome browser
AA seq
1530 aa
AA seq
DB search
MEVSPLQPVNENMKIDKIKKNEDAKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQ
MWVYDEDVGINYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWN
NGKGIPVVEHKVEKMYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVE
TASREYKKMFKQTWRDNMGRAGEMELKPFNGEDYTCITFQPDLSKFKMQSLDKDIVALMV
RRAYDIAGSTKDVKVFLNGNKLPVKGFRSYVDMYLKDKVDETGNPLKVIHEQVNHRWEVC
LTMSEKGFQQISFVNSIATSKGGRHVDYVADQIVAKLVDVVKKKNKGGVAVKAHQVKNHM
WIFVNALIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQ
VQLNKKCSAVKHNRIKGIPKLDDANDAGGRNSTECTLILTEGDSAKTLAVSGLGVVGRDK
YGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMT
DQDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEMAFYSLPEFEEWKS
STPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQIDD
RKEWLTHFMEDRRQRKLLGLPEDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVD
GLKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNN
LNLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEW
YIPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLMDGEEPLPMLPSYKNFKGTIE
ELAPNQYVISGEVAILDSTTIEISELPIRTWTQTYKEQVLEPMLNGTEKTPPLIADYREY
HTDTTVKFVVKMTEEKLAEAEKVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYETVLDILR
DFFELRLKYYGLRKEWLLGMLGAESAKLNNQARFILEKIEGKIIIENKPKKEIIKVLIQR
GYDSDPVKAWKEAQQKVPDEEENEESDNEKETEKSDSVTDSGPTFNYLLDMPLWYLTKEK
KDELCKLRNEKEQELDTLRKKTPSDLWKEDLAAFIEELEAVEAKEKQDEQVGLPGKGGKA
KGKKIQMAEVLPSPRGKRVIPRVTVEMKAEAEKKNRKKIKTENTEGSPQEDGMELESLKQ
RLEKKQKREPGTKTKKQTTLPFKPVKKGRKRNPWSDSESDMSSNESNFDVPPRKTEPRKT
TKTKFTMDLDSDEDFSDFDEKTQDEDFVLSDASPPKTKTSPKHTSKELKPQNSAKSEKDL
EANDKDSIPLSSSPLASDFSAETEIINPIPKKNVAVKKTAAKSQSSTSTTGAKKAAPKGT
KRNPALNSGVSQKPDPAKTKNRRKRKPSTSDDSDSNFEKIISKAATSKKSKGESDDFNLD
FDAAVAPRAKSSRAKKPIKYLEESDEDDLF
NT seq
4593 nt
NT seq
+upstream
nt +downstream
nt
atggaggtgtcaccactgcagcctgtaaatgaaaatatgaaaatcgacaaaataaagaaa
aatgaagatgctaagaaaagactgtctattgaaaggatctatcaaaagaaaacgcaattg
gaacatattttgctccgcccagacacctacattggctctgtggaattagtgacccagcaa
atgtgggtttatgatgaagatgttggcattaactatagggaagtcacttttgttcctggt
ttgtacaaaatctttgatgagattctagttaatgctgcggacaacaaacaaagggacccc
aaaatgtcttgcattagagtcacaattgacccggaaaacaatttaattagtatatggaat
aatggaaaaggtattcctgttgttgaacacaaagttgagaagatgtatgtcccagctctc
atatttggacagctcctaacttctagtaactatgatgatgatgaaaagaaagtaacaggt
ggtcgaaatggctatggagccaaattgtgtaacatattcagtaccaaatttactgtggag
acagccagtagagaatacaagaaaatgttcaaacagacatggagggataatatggggaga
gctggtgagatggaactcaagccctttaatggagaagattatacatgtatcaccttccag
cctgatttgtctaagtttaaaatgcaaagcctggacaaagatattgttgcactgatggtt
agacgagcatatgatattgctggatctaccaaagatgtcaaagtctttcttaatggaaat
aagctgccagtaaaaggatttcgtagttatgtggatatgtatttgaaagataaggtagat
gaaactggcaacccattaaaagtaatacatgaacaagtaaaccacaggtgggaagtatgt
ttaacaatgagcgaaaaaggctttcaacaaattagctttgtcaacagcattgctacttcc
aagggtggcagacatgttgattatgtagctgatcagattgtggctaaacttgttgatgtt
gtgaagaagaagaacaagggtggtgttgcagtaaaagcacatcaggtgaaaaatcacatg
tggatttttgtgaatgccttaattgaaaacccaaccttcgactctcagacaaaagaaaac
atgactttacaagccaagagctttggatcaacatgccaattaagtgaaaaatttatcaaa
gctgcaattgggtgtggtattgtagaaagcatactaaactgggtgaagtttaaggcccaa
gtccagttaaacaagaagtgttcagctgtaaaacataacagaatcaagggaattcccaaa
cttgatgatgccaatgatgcagggggccgaaactccactgagtgtacacttattctgact
gaaggagactcagccaaaactttggctgtttcaggccttggtgtggttgggagagacaaa
tatggggttttccctcttagaggaaaaatactcaacgttcgagaagcttctcataaacag
atcatggaaaatgctgaaataaacaatatcatcaagattgtgggtcttcagtacaagaaa
aactatgaagatgaagattcattgaagactcttcgttatggaaagataatgattatgaca
gatcaggaccaagacggttcccatatcaaaggcttgctgattaattttatccatcacaac
tggccctctcttctgagacatcgttttctggaggaatttatcactcccattgtaaaggtg
tctaaaaacaagcaagaaatggcattctatagccttcctgaatttgaggaatggaagagt
tccacaccaaatcataaaaaatggaaagtcaagtattacaaaggtttgggcaccagcaca
tcaaaggaagctaaagaatactttgcagatatgaaaagacatcgtatccagtttaaatat
tctggtcctgaagatgatgctgcaatcagcctggcctttagcaaaaaacagatagacgat
cgaaaggaatggttaactcatttcatggaggatagaagacaacgaaagttacttggcctt
cctgaggattacttgtatgggcaaactaccacatatctgacatataatgacttcataaac
aaggaacttatcttgttctcaaattccgataatgagagatctatcccatctatggtggat
ggtttgaaaccaggtcagagaaaggttttgtttacttgtttcaaacggaatgacaagcga
gaggtgaaggttgcccagttagctgggtcagtggctgaaatgtcttcttatcatcatggt
gagatgtcactgatgatgaccattatcaatttggctcagaattttgtgggtagcaataat
ctaaacctcttgcagcctattggtcagtttggtaccaggctacatggtggcaaggattct
gctagtcctcgatacatcttcacaatgctcagccctttggctcggttgttatttccacca
aaagatgatcacacattaaggttcttatatgatgacaaccaacgtgttgagcctgaatgg
tacattcctattatacccatggtcctgataaatggagctgaaggaataggtactgggtgg
tcctgcaaaatccccaactttgatgttcgtgaagttgtaaataacatcaggcgtttgatg
gatggagaagaacctctgccaatgcttccaagttacaagaacttcaagggtactattgaa
gagctggctccaaatcaatatgtgattagtggtgaagtagctattcttgattccacaacc
attgaaatctcagagcttcccatcagaacatggacccaaacatataaggagcaggttcta
gaacccatgttgaatggcactgagaagacaccccctctcatagcagactatagggaatac
catacagacaccactgtaaaatttgttgtgaagatgactgaagaaaaactggcagaggca
gagaaagttggactacacaaagtcttcaaactccaaaccagtctcacatgcaactctatg
gtactttttgaccacgtgggctgtttaaagaaatatgaaacagtgttggatattctaaga
gacttctttgaactcaggcttaaatattatggattaagaaaagaatggcttttaggaatg
cttggtgctgaatctgctaaactgaacaatcaggctcgctttatcttagagaaaatagag
ggcaaaataatcattgaaaataagccgaagaaagaaataattaaagttctgattcagagg
ggatatgattcggatcctgtgaaggcctggaaagaagcccagcaaaaggttccagatgaa
gaagaaaatgaagagagtgacaatgaaaaggaaactgaaaagagtgactctgtaacagat
tctggaccaaccttcaactacctgcttgatatgcccctttggtatctaaccaaggaaaag
aaagatgaactgtgcaaactaagaaatgaaaaagagcaagagttggacacattaaggaaa
aagactccatcagatttgtggaaagaagacttggctgcttttattgaagaactggaggct
gttgaagccaaggaaaaacaagatgaacaagttggacttccggggaaaggggggaaagca
aaggggaaaaaaattcaaatggctgaagttttgccttctccacgtggaaaaagagtcatt
ccccgagtgaccgtagaaatgaaagcagaggcagaaaagaaaaatagaaagaaaattaag
actgaaaatactgaaggaagccctcaagaggatggtatggaactagaaagcctaaaacaa
agattagagaagaaacagaaaagagaaccaggtaccaagacaaagaaacaaactacattg
ccatttaaaccagtcaaaaaaggaaggaagagaaatccctggtctgattcagaatcagat
atgagcagtaacgaaagtaattttgatgtccctccacgaaaaacagagccacggaaaaca
acaaaaaccaaattcacaatggatttggattcagatgaagatttctcagattttgatgaa
aaaactcaagatgaagattttgtcttgtcagatgctagtccacctaaaaccaaaacttcc
ccaaaacatactagcaaagaactgaagccacagaacagtgctaagtcagaaaaggacctt
gaggctaatgataaagacagtataccactttcttcaagccctcttgcttctgatttctcc
gctgaaactgaaattataaacccaattcctaaaaagaatgtggcagtgaagaagacggca
gcaaaaagtcagtcttctacttccaccacgggtgccaaaaaggctgccccaaaaggaacc
aaaaggaatccagccttgaattctggtgtctctcagaagcctgatcctgccaaaaccaaa
aatcgacgcaaaagaaagccatccacttctgatgattctgactctaattttgagaaaatt
atttctaaagcagccacaagcaaaaaatccaagggggagagtgacgacttcaatctagat
tttgatgcagcagttgctcctcgggcaaaatccagtcgggcgaagaaacctataaagtac
ctcgaggagtcagatgaagatgatctgttctaa
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integrated database retrieval system
