KEGG   Lemur catta (Ring-tailed lemur): 123621031
Entry
123621031         CDS       T08326                                 
Symbol
ITGA2B
Name
(RefSeq) integrin alpha-IIb isoform X1
  KO
K06476  integrin alpha 2B
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat04015  Rap1 signaling pathway
lcat04151  PI3K-Akt signaling pathway
lcat04510  Focal adhesion
lcat04512  ECM-receptor interaction
lcat04611  Platelet activation
lcat04613  Neutrophil extracellular trap formation
lcat04640  Hematopoietic cell lineage
lcat04810  Regulation of actin cytoskeleton
lcat04820  Cytoskeleton in muscle cells
lcat05165  Human papillomavirus infection
lcat05200  Pathways in cancer
lcat05222  Small cell lung cancer
lcat05410  Hypertrophic cardiomyopathy
lcat05412  Arrhythmogenic right ventricular cardiomyopathy
lcat05414  Dilated cardiomyopathy
lcat05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    123621031 (ITGA2B)
   04151 PI3K-Akt signaling pathway
    123621031 (ITGA2B)
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    123621031 (ITGA2B)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    123621031 (ITGA2B)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    123621031 (ITGA2B)
   04810 Regulation of actin cytoskeleton
    123621031 (ITGA2B)
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    123621031 (ITGA2B)
   04611 Platelet activation
    123621031 (ITGA2B)
   04613 Neutrophil extracellular trap formation
    123621031 (ITGA2B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    123621031 (ITGA2B)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    123621031 (ITGA2B)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    123621031 (ITGA2B)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    123621031 (ITGA2B)
   05410 Hypertrophic cardiomyopathy
    123621031 (ITGA2B)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    123621031 (ITGA2B)
   05414 Dilated cardiomyopathy
    123621031 (ITGA2B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:lcat01009]
    123621031 (ITGA2B)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:lcat04147]
    123621031 (ITGA2B)
   04515 Cell adhesion molecules [BR:lcat04515]
    123621031 (ITGA2B)
   04090 CD molecules [BR:lcat04090]
    123621031 (ITGA2B)
Protein phosphatases and associated proteins [BR:lcat01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     123621031 (ITGA2B)
Exosome [BR:lcat04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   123621031 (ITGA2B)
Cell adhesion molecules [BR:lcat04515]
 Integrins
  Integrin alpha subunits
   123621031 (ITGA2B)
CD molecules [BR:lcat04090]
 Proteins
  123621031 (ITGA2B)
SSDB
Motif
Pfam: Integrin_A_Ig_3 Integrin_A_Ig_2 Integrin_A_Ig_1 FG-GAP FG-GAP_3 Integrin_alpha ITGAX-like_Ig_3
Other DBs
NCBI-GeneID: 123621031
NCBI-ProteinID: XP_045382698
LinkDB
Position
15:complement(40857235..40871123)
AA seq 1074 aa
MARALCLLHALWLLEWALLLLGPGTAPPAWALNLDPVRLTFYTGPNASHFGFSLDFHKDS
HGSVAIVVGAPRALGPSQEETGGVFLCPWRAEGGQCTSLLFDLSDETRNVGSQILQTFKA
RQGLGASVISWRDNIVACAPWQHWNALEKTEEAEKTPVGGCFVAQLQNGGRAEYSPCRAN
TMSSVYAKTHFSLDRRYCEAGFSSVVTQAGELVLGAPGGYFFVGLLARAPIANIISSYRP
GTLLWHVPTQGFTEDFSSPEYFDGYRGYSVAAGEFDGNLETTEYVFGAPTWSWTLGAVEI
LDSYFHTLHRLHGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVY
LFLQPRSLHTLGSPSLLLTGTQLYGRFGSAIAPLGDLNRDGYNDVAVAAPYGGPSGRGQV
LVFLGQSEGLSSHPSQVLDSPFPPSSGFGFSLRGAVDIDDNGYPDLLVGAYGANKVAVYR
AQPVVIATVQLLVQDSLNPTVKNCVLPQTKTPVSCFNIQMCVGATGHNIPQKLRLNAELQ
LDRQKPRQGRRVLLLDSQQASTTLNLDLGGRHSPICQTTTAFLRDEADFRDKLSPIVLSL
NVSLPPREAGVAPAVVLHGDTHVQEQTRIILDCGEDNVCVPQLQLTANVTGSPLLVGADN
VLELHMDAANKGEGAYEAELATRLPSGAHYMQALSNLEGFERLTCNQKKENETKVVLCEL
GNPMKKNARIRITMLVSVGNLEEAGEYVSFQLQIRSKNSQNPNSETVPLNVPVRAEAQVE
LRGNSFPASLVVAAEEGDREPNSSDSLGPKVEHTYELHNNGPGTVSGLRLSVHLPSQSQP
SDLLYILDVQPQGGLECSPQPSPNPLKLDRRLPTPSPSPVHPGHHRRERRHAFPPGPKQP
SRLQDLVLVSCDSAPCTVVQCELREMARGQRAMVTVLAFLWLPSLRQRPLDQFELQSHAW
FNVSSLPYAVPALSLPSGEAVVRTKLLRVAEERPIPIWWVLVGALGGLLLLTLLVLAMWK
AEDLAAGWLLAYFLTDARGPKDHLYTLTLAPGHPQLGFFKRNQPPLEEEDEEEE
NT seq 3225 nt   +upstreamnt  +downstreamnt
atggccagagctttgtgtctactacatgccctctggcttctggagtgggcgctgctgctc
ttgggacctggtactgcccctcctgcctgggccttgaacctggacccagtgcggctcacc
ttctatacaggccccaatgccagccactttgggttttcactggacttccacaaggacagc
catgggagtgtggccatcgtggtgggcgccccgcgggccctgggccccagccaagaggag
acaggtggcgtgttcctgtgcccctggagggccgagggcggccagtgcacctcactactc
ttcgacctcagtgatgagacccgaaacgtaggctcccaaattttgcaaacattcaaggcc
cggcaaggactgggggcgtcggtcatcagctggcgcgacaacatcgtggcttgcgcccct
tggcagcactggaacgccctagaaaagaccgaggaggctgagaagacgcctgtcggtggc
tgcttcgtggctcagctccaaaacggcggccgcgcggagtactctccctgccgagcgaac
accatgagcagtgtttatgcaaaaactcattttagcctggacaggcgatactgcgaagct
ggcttcagctcagtggtcacccaggctggagaactggtgcttggggctcctggcggctat
tttttcgtaggtctcctggcccgagctccaattgccaatatcatctcgagttaccgcccg
ggcactcttttgtggcacgtgcccacccagggcttcaccgaggacttcagcagcccagag
tacttcgacggctaccgggggtactcagtggccgcgggcgaattcgacgggaatctcgaa
actacagagtatgtcttcggtgcccctacttggagctggaccctgggagcggtggaaatt
ttggactcctacttccacacgctgcaccggctgcacggagagcagatggcttcgtatttc
gggcactcagtagcagtcactgacgtcaacggggatgggaggcatgacctgctagtgggt
gctccactgtacatggagagccgggcagaccgcaagctggccgaggtggggcgtgtgtac
ttgttcctgcagcccagaagcctccacaccctgggctcccccagcctcctgctgaccggc
acacagctctatgggcgatttggctctgccattgctcctctgggcgacctcaaccgggat
ggctacaatgatgttgcagtggctgctccctacgggggtcccagtggtcggggccaagtg
ctggtgttcctgggtcagagtgaggggctgagctcacacccctcacaggtcctggacagc
cccttccccccaagctctggctttggcttctcccttcgaggtgctgtagacattgatgac
aacggatacccagacctgctggtgggagcttacggggccaacaaggtggctgtgtacaga
gctcagccagtggtgatagccactgtccagttgttggtgcaagattcactgaatcctact
gtgaagaactgtgtcctgccccagaccaagacaccagtgagctgcttcaatatccagatg
tgtgtgggagccactgggcacaacattcctcagaagctgcgcctaaatgccgagctgcag
ctggacaggcagaagccccgccagggccggcgggtgctcctcctggactctcaacaggcg
agcaccaccttgaacctggacctgggaggaaggcacagccccatctgccaaaccaccaca
gccttccttcgagacgaggcagacttccgggacaagctaagtcccatcgtgctcagcctc
aatgtgtccctgccccccagagaggctggagtagcccctgctgtcgtgctgcacggagac
acccatgtccaggagcagacccgcatcatcctggactgtggggaagacaatgtgtgtgtg
ccccagcttcagctcactgccaacgtgacgggctccccgctgctagttggggcagataat
gtgctagagctgcacatggacgcagccaacaagggcgagggggcctatgaggcagagctg
gccacgcgcctgccctcgggggcccactacatgcaggccctcagcaacctggagggcttt
gagaggctcacctgtaaccagaagaaagagaacgagaccaaggtggtgctgtgtgagcta
ggcaaccccatgaagaagaacgcccggataagaatcacgatgttggtgagtgtggggaac
ctggaagaggctggagagtatgtgtccttccagctacagatcaggagcaaaaacagccag
aatccaaacagcgagactgtgccactgaatgtacccgtccgggcagaggcccaagtggag
ctgcgagggaactcctttccagcctccctggtggtggcagcagaagaaggtgacagggag
ccgaacagctccgacagcctgggccccaaagtggagcacacctatgagctccacaacaac
ggccctgggactgtgagtggcctccgcctcagcgtccacctccccagccagtctcagccc
tctgacctgctctacatcctggacgtacagccgcaggggggccttgagtgctccccacag
ccctcccccaaccctctcaagctggaccggaggctgcccacccccagcccttcccccgtt
caccccgggcatcaccggcgggagcgcagacacgccttcccaccggggcccaagcagccc
tcgaggcttcaggatctggttcttgtgagctgcgactcggcgccctgtacggtggtgcag
tgtgagctgcgggagatggcacgcgggcagcgggccatggtcaccgtgctggccttcctg
tggctgcccagcctccgccagaggcccttggatcagtttgagctccagtcccacgcttgg
ttcaacgtctcctcccttccctacgcggtgcccgcgctcagcctgcccagcggggaagct
gtggtgcggacaaagctgcttcgggtcgctgaggaaaggcctattccaatctggtgggtg
ctggtgggcgcgctgggcggcctgctgctgctcaccctcctggtcctggccatgtggaag
gcagaggacctcgcagctggctggcttctagcatactttcttaccgatgctcgggggcct
aaggatcatctctacaccctgaccctggcccctgggcacccccagcttggcttcttcaag
cggaatcagccacccctggaagaagaagatgaagaggaggagtga

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