Lemur catta (Ring-tailed lemur): 123626067
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Entry
123626067 CDS
T08326
Symbol
ATP2A2
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 2 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat04020
Calcium signaling pathway
lcat04022
cGMP-PKG signaling pathway
lcat04024
cAMP signaling pathway
lcat04148
Efferocytosis
lcat04260
Cardiac muscle contraction
lcat04261
Adrenergic signaling in cardiomyocytes
lcat04380
Osteoclast differentiation
lcat04919
Thyroid hormone signaling pathway
lcat04972
Pancreatic secretion
lcat05010
Alzheimer disease
lcat05017
Spinocerebellar ataxia
lcat05022
Pathways of neurodegeneration - multiple diseases
lcat05410
Hypertrophic cardiomyopathy
lcat05412
Arrhythmogenic right ventricular cardiomyopathy
lcat05414
Dilated cardiomyopathy
lcat05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
123626067 (ATP2A2)
04024 cAMP signaling pathway
123626067 (ATP2A2)
04022 cGMP-PKG signaling pathway
123626067 (ATP2A2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
123626067 (ATP2A2)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
123626067 (ATP2A2)
09153 Circulatory system
04260 Cardiac muscle contraction
123626067 (ATP2A2)
04261 Adrenergic signaling in cardiomyocytes
123626067 (ATP2A2)
09154 Digestive system
04972 Pancreatic secretion
123626067 (ATP2A2)
09158 Development and regeneration
04380 Osteoclast differentiation
123626067 (ATP2A2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
123626067 (ATP2A2)
05017 Spinocerebellar ataxia
123626067 (ATP2A2)
05022 Pathways of neurodegeneration - multiple diseases
123626067 (ATP2A2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123626067 (ATP2A2)
05412 Arrhythmogenic right ventricular cardiomyopathy
123626067 (ATP2A2)
05414 Dilated cardiomyopathy
123626067 (ATP2A2)
05415 Diabetic cardiomyopathy
123626067 (ATP2A2)
Enzymes [BR:
lcat01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
123626067 (ATP2A2)
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Ortholog
Paralog
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
Motif
Other DBs
NCBI-GeneID:
123626067
NCBI-ProteinID:
XP_045390808
LinkDB
All DBs
Position
21:complement(26240676..26298898)
Genome browser
AA seq
1042 aa
AA seq
DB search
MENAHTKTVEEVLGHFGVNESTGLSLEQVKKLKEKWGSNELPAEEGKTLLELVIEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALK
EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV
ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMK
KEFTLEFSRDRKSMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHVRVGSTKVPLTPGV
KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYETNLTFVGCVGMLD
PPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQDEDVTSKAFTGREFDEL
NPSAQRDACLNARCFARVEPSHKSKIVEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GFPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIG
CYVGAATVGAAAWWFIAADGGPRVTFYQLSHFLQCKEDNPDFDGVDCEVFESPYPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWENIWLVGSICLSMSLHFLILYVEPLPLIFQITP
LNVTQWLMVLKISLPVILMDETLKFVARNYLEPGKECVRPATKSCSLSACTDGISWPFVL
LIMPLVVWVYSTDTNFSDMFWS
NT seq
3129 nt
NT seq
+upstream
nt +downstream
nt
atggagaacgcgcacacaaagacggtggaggaggtgctgggccacttcggcgtcaacgag
agcaccgggctgagcctggagcaggtcaagaagctcaaagagaaatggggctccaacgag
ttacctgctgaagaaggaaaaaccttgctggaacttgtgattgagcagtttgaagactta
ctagttagaattttattattggcagcatgtatatcttttgttttggcttggtttgaagaa
ggtgaagaaacaattacagcctttgtagaaccttttgtaattttacttatattagtagcc
aatgcaattgtgggtgtatggcaggaaagaaatgctgaaaatgcaatcgaagcccttaag
gaatatgagcctgaaatgggcaaagtatatcgacaggacagaaagagtgtacagcggatt
aaagctaaagacatagttcctggcgatattgtagaaattgctgttggtgacaaagttcct
gctgatataagattaacttccatcaaatctacaactctaagagttgaccagtcgattctc
acaggtgaatctgtctctgtcatcaagcacactgaccctgtccctgacccacgggctgtc
aaccaagataagaagaacatgctcttttctggtacaaacattgctgctgggaaagctatg
ggagtggtagtggcaactggagttaacactgaaattggcaagatccgggatgaaatggtg
gccacggaacaggagagaacaccgcttcagcagaaactagatgagtttggggaacagctt
tccaaagtcatatcccttatttgcattgctgtctggatcataaacattgggcacttcaat
gacccagttcacggaggctcctggatcagaggtgctatttactactttaaaattgcggtg
gccttggctgtagcagccattcctgaaggtctgcctgctgttatcaccacctgcctggct
cttggaactcgcagaatggcaaagaagaatgccatcgttcgaagcctcccttctgtggaa
accctcggttgtacttctgttatctgctcagacaagactggtacacttacaacaaaccag
atgtcagtctgcaggatgttcattctggacagagttgaaggtgatacttgttcccttaat
gagtttaccataactggatcaacatatgcacctattggagaagtgcataaagatgataag
ccagtaaactgtcaccagtatgatggtcttgtagaattagcaacaatttgtgctctttgt
aatgactctgccttggattacaatgaggcaaagggtgtgtatgaaaaagttggagaagct
acggagaccgctctaacttgcctggtagagaagatgaatgtatttgataccgaattgaag
ggtctttctaaaatagaacgtgcaaacgcctgcaactcggtcataaaacagctgatgaaa
aaggaatttactctagagttttcacgtgatagaaaatcaatgtcagtttactgtacacca
aacaaaccaagcaggacatcgatgagcaagatgtttgtgaagggcgctcctgaaggtgtc
atcgacaggtgcacccatgttcgagttggaagtaccaaggtgcctctgacccctggagtc
aaacagaagatcatgtctgtcattcgggagtggggtagcggcagcgacaccctgcgatgc
ctggccctggccactcacgacaacccgctgagaagagaagaaatgcaccttgaggactct
gccaactttattaaatatgagaccaacctgacgttcgtcggctgcgtgggcatgctggac
cccccgaggattgaggtggcctcctccgtgaagctgtgccgccaggcaggcatccgagtc
atcatgatcacaggggacaacaagggcactgccgtggccatctgccgccgtatcggcatc
ttcgggcaggatgaggacgtgacgtcaaaggcttttacaggtcgggagtttgatgaactc
aacccctcagcccagagagatgcctgcttgaatgcccgctgttttgctcgagttgaacct
tcccacaagtctaaaatcgtagaatttcttcagtcttttgatgagattacagctatgacc
ggcgatggtgtgaatgatgctcctgctctgaagaaagccgagatcggcattgctatgggc
tctggcactgcggtggctaaaactgcctccgagatggtcctggcagatgacaacttctcc
accatcgtggctgctgtcgaggaggggcgggcaatatacaacaacatgaagcagttcatc
cgctacctcatctcatctaacgtgggggaagttgtctgtattttcctgacagcagccctg
ggatttcctgaggctttaattcctgtccagctgctctgggtcaatctggtgacagacggc
ctgcctgccactgcactggggttcaaccctcctgacctggacatcatgaataagccacct
cggaacccaaaagaaccgctgatcagtgggtggctgtttttccgttacctggctattggc
tgttatgtcggcgccgctaccgtgggtgctgctgcgtggtggttcattgctgctgacggc
ggtccaagagtgaccttctaccagctgagtcatttcctacagtgtaaagaggataatcca
gactttgacggagtagattgtgaagtctttgagtctccgtaccccatgaccatggcgctc
tctgtgctagtaaccatagagatgtgtaacgcccttaacagcttgtctgaaaaccagtcc
ttgctgaggatgcccccttgggagaacatctggctcgtgggctccatctgcctgtccatg
tcgctccacttcctgatcctctacgtagaacccttgccactcatcttccagatcacaccg
ctgaatgtgacccagtggctgatggtgctgaaaatctccttgcctgtgattctcatggac
gagacgctcaagtttgtggcccgcaactacctggaacccggtaaagagtgtgtgcgtcct
gccaccaaatcctgctcgctctcggcatgcaccgatgggatttcctggccgtttgtgctg
ctcataatgcccctggtggtctgggtctatagcacagacactaactttagtgatatgttc
tggtcttga
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