| Entry |
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| Symbol |
PLAT
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| Name |
(RefSeq) tissue-type plasminogen activator isoform X1
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| KO |
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| Organism |
lcat Lemur catta (Ring-tailed lemur)
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| Pathway |
| lcat04610 | Complement and coagulation cascades |
| lcat05202 | Transcriptional misregulation in cancer |
| lcat05418 | Fluid shear stress and atherosclerosis |
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| Brite |
KEGG Orthology (KO) [BR:lcat00001]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
123626610 (PLAT)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
123626610 (PLAT)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
123626610 (PLAT)
09162 Cancer: specific types
05215 Prostate cancer
123626610 (PLAT)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
123626610 (PLAT)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:lcat01002]
123626610 (PLAT)
09183 Protein families: signaling and cellular processes
00536 Glycosaminoglycan binding proteins [BR:lcat00536]
123626610 (PLAT)
Enzymes [BR:lcat01000]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.21 Serine endopeptidases
3.4.21.68 t-plasminogen activator
123626610 (PLAT)
Peptidases and inhibitors [BR:lcat01002]
Serine peptidases
Family S1: chymotrypsin family
123626610 (PLAT)
Glycosaminoglycan binding proteins [BR:lcat00536]
Heparan sulfate / Heparin
Coagulation and fibrinolysis
123626610 (PLAT)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
22:5463342..5487265
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| AA seq |
560 aa
MKTELLCALLLCGAVFASPSQDVRARFRRGARSSQVTCRDEKTQMMYQQHESWLRPVLRS
NRVEYCRCSGGRAQCHSVPVKGCSEPKCFNGGTCLQALYFSDFVCQCPEGFAGKRCEIDA
RATCYEDQGVTYRGTWSTAESGAECVSWNSSALARKPYSARRPDAIRLGLGNHNYCRNPD
QDSKPWCYVFKAGKYSSEFCSTPACSKRENGDCYFGKGSAYRGSHSLTTSGASCLPWNSA
SLVGKVYTAWKRSARALGLGQHNHCRNPDGDVKPWCHVMKDGKLTWEYCDMPQCSTCGLR
QHRQPQFRIKGGLFADITSHPWQAAIFVRNRRSPGERFLCGGVLIASCWVLSAAHCFQDR
FPPHHLTVILGRTYRVVPGGEEQRFEVEKYIVHQEFDDDTYNNDIALLQLRSDAPRCARE
GSSVRAVCLPEADLRLPDWTECELSGYGKHEASSLSYSERLKEAHVRLYPSSRCTSQHLF
NRTVTSNMLCAGDTRSGGDQANLHDACQGDSGGPLVCLKDNRMTLVGIISWGLGCGQKDV
PGVYTKVTRYLDWIRDNTRL |
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| NT seq |
1683 nt +upstreamnt +downstreamnt
atgaagacagagctcttgtgcgcgctgctgctttgtggagcagtcttcgcttcgcccagc
caggacgtccgcgcccggttccgaagaggagccaggtcctcccaagtgacctgcagagac
gagaaaacacagatgatgtaccagcaacacgagtcgtggctgcggcccgtgctcagaagc
aaccgggtggaatactgcaggtgcagcggcggtagggcgcagtgccactcggtgcccgtc
aagggctgcagtgaaccaaagtgcttcaacggagggacgtgtctgcaggctttgtacttc
tcagattttgtctgccagtgccctgaaggctttgctggaaaacgctgtgaaattgatgcc
agggccacatgctacgaggaccagggtgtcacctacaggggcacgtggagcacggcagag
agtggtgccgagtgtgtcagctggaacagcagcgcgctggcccggaagccctacagcgcg
cggaggccggacgccatcaggctgggcctcgggaaccacaactactgcagaaacccggac
caagactcaaagccctggtgctatgtcttcaaggcagggaagtacagctcggagttctgc
agcacacccgcctgctccaagcgagaaaatggggactgttactttggaaaagggtcagcg
taccgaggcagccacagcctcaccacgtctggggcctcctgcctcccgtggaattccgcg
agcctggtgggcaaggtttacacggcctggaagaggagcgcccgggccctgggcctgggc
caacacaaccactgccggaacccagacggggacgtcaagccctggtgccacgtgatgaag
gacggcaagctgacgtgggagtactgtgacatgccccagtgctccacctgcggcctgagg
cagcacaggcagccgcagttccgcattaagggaggactcttcgcggacatcacctcccat
ccttggcaggccgccatcttcgtcaggaacaggaggtccccgggggagcggttcctgtgc
gggggcgtcttgatcgcctcctgctgggtcctgtctgccgcccactgcttccaggacagg
tttcctccccaccacctcacggtgatcctgggcaggacgtaccgcgtggtccctggaggg
gaggagcagagatttgaagtagaaaaatacatcgtccaccaggaatttgatgatgacact
tacaacaatgacatcgccctgctgcagctgaggtccgacgcgccacgctgcgcgcgggag
ggcagctctgtccgcgccgtgtgtctccccgaggccgacctgcggctgcccgactggacg
gagtgcgagctgtccggctacggcaagcacgaggcgtcttctctttcctattcggagcgg
ctgaaggaggctcatgtcaggctgtacccgtccagccgctgcacgtcacagcacttgttc
aacagaaccgtcaccagcaacatgctgtgtgcgggagacactcggagcggaggggaccaa
gccaacctgcatgacgcctgccagggtgactccgggggccccttggtgtgtttgaaggac
aaccgtatgacattggtgggcataatcagctggggccttggctgtgggcagaaggacgtc
ccgggggtgtacaccaaggtcaccagatacctagactggatccgagacaatacgcgactg
tga |
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