Lemur catta (Ring-tailed lemur): 123626819
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Entry
123626819 CDS
T08326
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat04010
MAPK signaling pathway
lcat04020
Calcium signaling pathway
lcat04022
cGMP-PKG signaling pathway
lcat04024
cAMP signaling pathway
lcat04260
Cardiac muscle contraction
lcat04261
Adrenergic signaling in cardiomyocytes
lcat04270
Vascular smooth muscle contraction
lcat04723
Retrograde endocannabinoid signaling
lcat04725
Cholinergic synapse
lcat04726
Serotonergic synapse
lcat04727
GABAergic synapse
lcat04911
Insulin secretion
lcat04912
GnRH signaling pathway
lcat04921
Oxytocin signaling pathway
lcat04924
Renin secretion
lcat04925
Aldosterone synthesis and secretion
lcat04927
Cortisol synthesis and secretion
lcat04929
GnRH secretion
lcat04934
Cushing syndrome
lcat04935
Growth hormone synthesis, secretion and action
lcat05010
Alzheimer disease
lcat05020
Prion disease
lcat05022
Pathways of neurodegeneration - multiple diseases
lcat05207
Chemical carcinogenesis - receptor activation
lcat05410
Hypertrophic cardiomyopathy
lcat05412
Arrhythmogenic right ventricular cardiomyopathy
lcat05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
123626819 (CACNA1S)
04020 Calcium signaling pathway
123626819 (CACNA1S)
04024 cAMP signaling pathway
123626819 (CACNA1S)
04022 cGMP-PKG signaling pathway
123626819 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
123626819 (CACNA1S)
04929 GnRH secretion
123626819 (CACNA1S)
04912 GnRH signaling pathway
123626819 (CACNA1S)
04921 Oxytocin signaling pathway
123626819 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
123626819 (CACNA1S)
04924 Renin secretion
123626819 (CACNA1S)
04925 Aldosterone synthesis and secretion
123626819 (CACNA1S)
04927 Cortisol synthesis and secretion
123626819 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
123626819 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
123626819 (CACNA1S)
04270 Vascular smooth muscle contraction
123626819 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
123626819 (CACNA1S)
04725 Cholinergic synapse
123626819 (CACNA1S)
04726 Serotonergic synapse
123626819 (CACNA1S)
04723 Retrograde endocannabinoid signaling
123626819 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
123626819 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
123626819 (CACNA1S)
05020 Prion disease
123626819 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
123626819 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
123626819 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
123626819 (CACNA1S)
05414 Dilated cardiomyopathy
123626819 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123626819 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
lcat04040
]
123626819 (CACNA1S)
Ion channels [BR:
lcat04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
123626819 (CACNA1S)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
123626819
NCBI-ProteinID:
XP_045392011
LinkDB
All DBs
Position
23:complement(3006512..3066884)
Genome browser
AA seq
1860 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEILPRPPRALFCLTLQNPLRKACISIVEWKPFETIILLT
IFANCVALAVYLPMPEDDNNSLNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFTIVFLGVFTVILEQVNVIQSNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSIFKAMLPLFHIALLVLFMVIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
EPSPCARMGSGRRCTINGSECRGGWPGPNHGITHFDNFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLE
EDLRGYMSWITQGEVMDVEDLREGRLSLDEGGSDTESLYEIVGLNKIVQFIRHWRQWNRI
FRWKCHDIVKSKVFYWLVILIVALNTLSIASEHHNQPLWLTHLQEVANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEVLLVESGAMTPLGISVLRCIRLLRIFKITK
YWTSLSNLVASLLNSIRSIASLLLLLFLFIVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALISVFQVLTGEDWTSMMYNGIMAYGGPSYPGMLVCIYFIILFVSGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERKRRKMSKGLPDKSEEKSTVAKKLEQKPKGEGIPTTAKLK
IDEFESNVNEVKDPYPSADFPGDDEEDEPEIPVSPRPRPLAELQLKEKAVPIPDASSFFI
FSPTNKIRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRAESMRNQILKHFDIGFTS
VFTVEIVLKMTTYGAFLHEGSFCRSYFNMLDLLVVAVSLISTGLESSAISVVKILRVLRV
LRPLRAINRAKGLKHVVQCMFVAISTIGNIVLVTTLLQFMFACIGVQLFKGKFYSCTDLS
KVTEEECRGYYYVYKDGDPTQIELRRREWVHSDFHFDNVLSAMMSLFTVSTFEGWPQLLY
KAIDSHEEDRGPVYNNRVEIAIFFIIYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCEL
DKNQRQCVQYALKARPLRCYIPKNPYQYQVWYVVTSSYFEYLMFALIMLNTICLGMQHYN
QSEEMNHISDILNVAFTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILSE
IDTFLASSGGLYCLGGGCGNVDPDESARISSAFFRLFRVMRLIKLLSRAEGVRTLLWTFI
KSFQALPYVALLIVMLFFIYAVIGMQMFGKIAMVDGTQINRNNNFQTFPQAVLLLFRCAT
GEAWQEILLACSYGKPCDPESDYAPGEEHTCGTNFAYYYFISFYMLCAFLIINLFVAVIM
DNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCPH
RVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKRT
SMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMKRQEEYYGYRPKKDIIQIQAGLRT
IEEEAAPEIHRTISGDLPAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFIERTNSLPPV
MANQRPLQFSEIEMEELESPVFLEDFPQDPRTNPLARANTNNANANVAGGNSNHSNNQVF
SSVRYETEFPGETETPAARGGALSQARRVLGPHSKPRVEELKGRLTQASPAHHQGPRPEE
RRSSTPGALCEETPHGRSTKDGTSRCPAPATALLIQEALVRGGLGTLATDADFVMATGHA
LADACQMEPEEVEVAATELLRGRESREGMTCALGCPSLRSSLDSLEQPQGSQETLIPPRL
NT seq
5583 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcaccccaggacgagggcctgaggaagaaacagcccaagaagccggtt
ccggagattttgccaaggccaccccgggccttgttctgcctgaccctgcagaaccccctg
aggaaggcctgcatcagcatcgtggaatggaaacccttcgagacgatcatcttgctcacc
atctttgccaactgtgtggccctggccgtgtacctgcccatgcctgaagatgacaacaac
tctctgaacctcggcctggagaaactggagtatttcttcctcatcgtcttctccatcgaa
gccgccatgaagatcattgcctacggcttcctattccaccaggacgcctacctgcgcagc
ggctggaacgtgctggacttcaccattgtcttcctgggggtcttcacggtgattctggaa
caggttaacgtcatccagagcaacacagcgcctatgagcagcaaaggagctggcctggac
gtcaaggccctgagggccttccgagtgctcagacccctgcggctggtgtcaggggtgccc
agcctgcaggtggtcctcaactccatcttcaaggccatgctgccgctgttccacatcgcc
ctgctggtcctctttatggtcatcatctatgccatcattgggctggagctcttcaagggc
aagatgcacaagacctgctacttcattggcacagacatcgtggccacggtggagaacgag
gagccgtcaccctgcgccaggatgggctcggggcgccggtgcaccatcaacggcagcgag
tgccggggcggctggccggggcccaaccacggcatcacccacttcgacaactttggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgatgccatcgggaatgagtggccctggatctattttgtcaccctcattctgctg
ggatccttcttcatcctcaacctggtgctgggtgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctccgggagaagcagcagctggag
gaggaccttcggggctacatgagctggatcacacagggcgaggtcatggacgtggaggac
ttgagagaagggaggctgtctttggacgaaggcggctccgacacggagagcctgtatgag
atcgtgggcttgaacaaaatcgtccagttcatccggcactggaggcagtggaaccgcatc
ttccgctggaagtgccacgacatagtgaagtccaaggtcttctactggctggtgatcctc
atcgtcgccctcaacaccctgtccatcgcctcggagcaccacaaccagcctctctggctg
acccatttgcaagaggtggccaaccgggtgctgctggcgctgttcacggtcgagatgctg
atgaagatgtacgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgcagcggtctcctggaggtcctgctggtggagtcgggcgccatgacg
ccgctgggcatctccgtgctccgctgcatccgcctcctgcggatcttcaagatcaccaag
tactggacgtccctgagcaacctggtggcctccctgctcaactccatccgctccatcgcc
tccctgctgctgctgctcttcctcttcatcgtcatcttcgccctcctgggcatgcagctg
ttcgggggcaggtatgattttgaggacacggaggtgcggcgcagcaacttcgacaacttc
ccccaggccctcatcagcgtcttccaggtcctgacgggcgaagactggacctcgatgatg
tacaatggcatcatggcgtacggcgggccgtcctaccccggcatgctcgtgtgcatttac
ttcatcatccttttcgtctccggcaactatatcctgctcaacgtcttcctggccatcgcc
gtggacaacctggccgaggcggagagcctgacttccgcccagaaggccaaggccgaggag
agaaaacgcaggaagatgtccaagggtctcccagacaagtcagaggagaagtccacggtg
gccaagaagctggaacagaaacccaagggtgagggcatccccaccacggccaagctgaaa
atcgacgagtttgaatctaacgtcaatgaggtgaaggatccctacccctcggctgacttc
ccaggggatgacgaggaagatgagcctgagatcccagtgagcccccgaccgcgccccctg
gccgagctgcagctgaaggagaaggcggtccccatcccggatgccagctccttcttcatc
ttcagccccaccaacaagatccgcgtcctgtgtcaccgcattgtcaacgccacctggttc
accaacttcatcctgctctttatcctgctcagcagtgctgcgctggccgccgaggacccc
atccgggccgagtccatgaggaatcagatcctcaagcactttgacatcgggttcacctct
gtcttcaccgtggagattgtcctcaagatgacgacctatggggccttcctgcacgagggc
tccttctgccgcagctacttcaacatgctggacctgctggtggtggctgtgtccctcatc
tccacgggcctcgagtccagcgccatctccgtggtgaagattctgagggtgctgagggtg
ctccgacccctccgagccatcaacagagccaaggggttgaagcacgtggtgcagtgcatg
ttcgtggccatcagcaccatcgggaacatcgtgctggtcaccaccctgctgcagttcatg
tttgcgtgcatcggcgtccagctcttcaaggggaagttctacagctgcacagacctgtcc
aaggtgaccgaggaggagtgcaggggctactactacgtgtacaaggatggggaccccacg
cagatagagctgcgtcgccgcgagtgggtgcacagcgacttccacttcgacaacgtgctc
tcagccatgatgtccctcttcaccgtgtccaccttcgagggctggcctcagctgctgtac
aaggccatagactcccatgaggaggacaggggccccgtctacaacaaccgagtagagata
gccatcttcttcatcatctacatcatcctcattgccttcttcatgatgaacatctttgtg
ggcttcgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgtgagctg
gacaagaaccagcgccagtgtgtgcagtacgccctgaaggcccgcccgctgcggtgctac
atccccaaaaacccgtaccagtaccaggtgtggtacgtcgtcacctcctcctactttgaa
tacctgatgtttgcactcatcatgctcaacaccatctgcctgggcatgcagcactacaac
caatcggaggagatgaaccacatctcagacatcctcaacgtggccttcaccatcatcttc
accctggagatgatcctcaagctcatggccttcaaggccaggggctattttggggacccc
tggaacgtgttcgactttctgattgtcatcggcagcatcatcgacgtcatcctcagcgag
atcgacactttcctggcctccagcgggggactgtattgcctgggtggaggctgcgggaac
gttgaccccgacgagagcgcccgcatctccagcgccttcttccgcctgttccgagtcatg
aggctgatcaagctgctgagccgggccgagggcgtgcgcaccctgctgtggacgttcatc
aaatccttccaggccctgccgtatgtggctctgctcatcgtcatgctcttcttcatctac
gctgtcatcggcatgcagatgttcggaaagatcgccatggtggacgggactcagatcaac
cggaacaacaacttccagaccttccctcaagccgtgttgctgctcttcaggtgtgcgaca
ggggaggcctggcaggagatcctgctggcctgcagctacgggaagccttgtgaccccgag
tcggactacgccccgggggaggagcacacgtgtggcaccaacttcgcctactactacttc
atcagcttctacatgctctgcgccttcctgatcatcaacctctttgtggctgtcatcatg
gacaactttgactacctcacccgggactggtccatcctgggccctcaccacctggatgag
ttcaaggccatctgggcagagtacgacccggaggcaaaggggaggatcaaacacctggat
gtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgcccgcac
cgggtagcgtgtaagcggctggtgggcatgaacatgcccctgaacagcgacggcacagtc
accttcaacgccacgctcttcgccctggtccgcacggcgctcaagatcaagacagaaggc
aactttgagcaggccaatgaggagctgagggccatcatcaagaagatttggaagagaacc
agcatgaagctcctggaccaggtcatccccccgataggagatgatgaggtgacagtgggc
aagttctacgccacgttcctcatccaagagcacttccggaagttcatgaagcgccaggag
gagtattacgggtatcggcccaagaaggacatcatacagatccaggccggactgcggacc
attgaggaggaggcggcccccgagatccaccgcaccatctcaggggacctgccggcggag
gaggagctggagcgagccatggtggaggctgcgatggaggagggaatcttccggaggacc
ggaggcctgtttggccaggtggacagtttcatcgagaggaccaactccctgccccccgtc
atggccaaccagagacccctccagttttctgagatagagatggaagagctggagtcacct
gtcttcttggaggacttccctcaggatccacgcactaaccctctggctcgtgccaatacc
aacaacgccaacgccaatgttgccggtggcaacagcaaccatagcaacaaccaggtgttt
tccagcgtgcgttacgagacggagttcccgggagagaccgagacacctgccgccagagga
ggagccctcagccaagcccgcagggtgctgggcccccacagcaaaccccgtgtggaagag
ttgaagggacggctgacccaggcatcgcctgcccaccaccagggcccccggcctgaggag
aggaggagctccacacccggggctctctgtgaggagacgccccatggcaggagcaccaag
gacggtacttccaggtgcccagccccagccacggccctgctgatccaagaggctctggtt
cgagggggcctgggcaccttggcgactgatgctgacttcgtcatggcaacaggccacgcc
ctggcagatgcctgccagatggagccagaggaagtggaggtcgcagcaacagagctcctg
agaggacgagagtcccgagagggcatgacctgtgccctgggatgcccaagccttaggtcc
tccctggacagcctcgagcagcctcagggctcccaggagaccctcattcctccccggctg
tga
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integrated database retrieval system
