KEGG   Lemur catta (Ring-tailed lemur): 123627239
Entry
123627239         CDS       T08326                                 
Symbol
PLCD1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 isoform X1
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
lcat  Lemur catta (Ring-tailed lemur)
Pathway
lcat00562  Inositol phosphate metabolism
lcat01100  Metabolic pathways
lcat04020  Calcium signaling pathway
lcat04070  Phosphatidylinositol signaling system
lcat04919  Thyroid hormone signaling pathway
lcat04933  AGE-RAGE signaling pathway in diabetic complications
Module
lcat_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:lcat00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    123627239 (PLCD1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    123627239 (PLCD1)
   04070 Phosphatidylinositol signaling system
    123627239 (PLCD1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    123627239 (PLCD1)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    123627239 (PLCD1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:lcat04131]
    123627239 (PLCD1)
Enzymes [BR:lcat01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     123627239 (PLCD1)
Membrane trafficking [BR:lcat04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    123627239 (PLCD1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    123627239 (PLCD1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like EF-hand_10 C2 PH_12 PH EF-hand_7 EF-hand_6 EF-hand_15 EF-hand_1 WHD_MCM8 SOS1_NGEF_PH TEP1_N EF-hand_5
Other DBs
NCBI-GeneID: 123627239
NCBI-ProteinID: XP_045392654
LinkDB
Position
1:144599560..144622315
AA seq 777 aa
MQCLGGRHRSSSRELYLQEQSLKVAALNGQRLGLQGDEDLLALLKGSQLLKVKSNSWRRE
RYYKLQEDCKTIWQESRKVMRTPESQLFSIEDIQEVRMGHRTEGLEKFARDVPEDRCFSI
VFKDQRNTLDLIAPSPADAQHWVQGLRKIIQHSGSMDQRQKLQHWIHSCLRKADKNKDNK
MSFKEVQNFLKELNIQVDDSYARKIFRECDRSQTDSLEDEEIEDFYKMLTKRQEIDRTFA
EAAGSGETLSVDQLVTFLQHQQREEAAGPALALSLIERYEPSETAKAQQQMTKDGFLMYL
LSADGSAFSLMHRRVYQDMNQPLSHYLVSSSHNTYLMEDQLTGPSSTEAYIRALCKGCRC
LELDCWDGPNLEPIIYHGYTFTSKILFCDVLRAIRDYAFKASPYPVILSLENHCSLEQQR
VMARHLRAILGPLLLDQPLDGVTTSLPSPEQLKGKILLKGKKFGGLLPTGGEGGSEATVV
SDEDEAAEMEDEAVRSRVQHKPKEDKLRLAQELSDMVIYCKSVHFGGFPSPGTPGQAFYE
MVSFSENRALRLLQESGNSFVRHNVEHLSRIYPAGWRTDSSNYSPVELWNGGCQIVALNF
QTPGPEMDVYQGRFQDNGACGYVLKPAFLRDPNSSFNSRALTQGPWWARKRLHIRVISGQ
QLPKVNKSKNSIVDPKVTVEIHGVSRDVASRQTTVITNNGFNPWWDMELEFEVVVPELAL
VRFVVEDYDASSKNDFIGQSTIPLNSLKQGYRHVHLLSKNGDQYPSATLFVKIALQD
NT seq 2334 nt   +upstreamnt  +downstreamnt
atgcagtgcctggggggccgacaccggagcagctccagggagctttacttgcaggagcag
agcctcaaggtggcagcgctcaatgggcagaggctgggcctacagggtgatgaggaccta
ctggccctgctgaagggcagccagctcctgaaggtgaagtccaactcatggcggagagag
cgctactacaagctgcaggaggactgcaagaccatctggcaggagtcccgcaaggtcatg
cggaccccggagtcccagttgttctccatagaggacattcaggaggtgcggatggggcac
cgcacagaaggcctggagaagtttgcccgtgacgtgcctgaggaccgctgcttctccatt
gtcttcaaggaccagcgcaatacactagacctcatcgccccatcaccagctgacgcccag
cactgggtgcagggtctgcgcaagatcatccaacactcgggctccatggaccagcggcaa
aagctccagcactggattcactcctgcttacgaaaagctgacaaaaacaaggacaacaag
atgagcttcaaggaggtgcagaacttcctaaaggagctcaacatccaggtggacgacagc
tacgcccggaagatcttcagggagtgtgaccgctcccagacagactccttggaggacgag
gagatcgaagacttctacaagatgctgacgaagcggcaggaaatcgaccgcaccttcgct
gaggctgcgggctcaggggagaccctgtccgtggatcagttagtgacgttcctgcagcac
cagcagcgggaggaggcggcagggcctgccctggccctctccctcattgagcgctacgag
cccagcgagactgccaaggcgcagcagcagatgaccaaggatggcttcctcatgtacctg
ctgtcagctgacggcagcgccttcagtctgatgcaccggcgggtctaccaggacatgaac
cagccactcagccactacctggtgtcctcctcacacaacacctacctgatggaggaccag
ctcaccgggcccagcagcaccgaagcctacatccgggcactgtgcaaaggctgccgctgc
ctggagctcgactgctgggacgggcccaacctggaaccaatcatctaccatggctatact
ttcacctccaagatcctcttctgcgacgtgctccgggccatccgggactacgccttcaag
gcatccccctaccctgtcatcttgtccctggagaaccactgcagcctagagcagcagcgt
gtgatggcgagacacctgcgggccatcctgggccccctgctgctggaccagccgctggat
ggggtcaccaccagcctgccctcccccgagcaactgaaggggaagatcctgctgaagggg
aagaagtttggggggctcctgcccactggaggggaaggcggctccgaggccacggtcgtg
tcggacgaagacgaggctgccgagatggaggatgaagcagtgaggagccgagtgcagcac
aagcccaaggaggacaagctcaggctagcgcaggagctctctgacatggtcatttactgc
aagagtgtccactttgggggcttccccagtcctggcacccccgggcaggctttctacgag
atggtgtccttctctgagaaccgcgccctccgactgctccaggaatcaggaaacagcttt
gtccgccacaacgtggagcacctgagcaggatctacccggctgggtggagaacagactcc
tccaactacagccccgtggagctgtggaacgggggctgccagatcgtggccttgaacttc
cagacacctgggccagagatggatgtgtaccagggccgcttccaggacaatggggcctgt
gggtacgtgctgaagcctgccttcctgagagaccccaattcgagcttcaactcgcgtgcc
ctgacgcaggggccctggtgggctcggaagcggctccacatcagggtcatctcagggcag
cagctgccaaaagtcaacaagagtaagaattccattgtggaccccaaggtgacggtagag
atccacggcgtgagccgggacgttgccagccgccagaccactgtgatcaccaacaacggt
ttcaacccgtggtgggacatggagctggagttcgaggtggttgtgcctgagctcgccctc
gtgcgcttcgtggtggaggattacgatgcctcctccaagaacgacttcatcggccagagc
accatccccttgaacagcctcaagcagggataccgccacgtccacctgttgtctaagaat
ggagaccagtatccatcggccaccctctttgtgaagatcgccctccaggactag

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