Lemur catta (Ring-tailed lemur): 123627578
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Entry
123627578 CDS
T08326
Symbol
FH
Name
(RefSeq) fumarate hydratase, mitochondrial
KO
K01679
fumarate hydratase, class II [EC:
4.2.1.2
]
Organism
lcat
Lemur catta (Ring-tailed lemur)
Pathway
lcat00020
Citrate cycle (TCA cycle)
lcat00620
Pyruvate metabolism
lcat01100
Metabolic pathways
lcat01200
Carbon metabolism
lcat04934
Cushing syndrome
lcat05200
Pathways in cancer
lcat05211
Renal cell carcinoma
Module
lcat_M00009
Citrate cycle (TCA cycle, Krebs cycle)
lcat_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
Brite
KEGG Orthology (KO) [BR:
lcat00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
123627578 (FH)
00620 Pyruvate metabolism
123627578 (FH)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
123627578 (FH)
09162 Cancer: specific types
05211 Renal cell carcinoma
123627578 (FH)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
123627578 (FH)
Enzymes [BR:
lcat01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.2 fumarate hydratase
123627578 (FH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Lyase_1
FumaraseC_C
Motif
Other DBs
NCBI-GeneID:
123627578
NCBI-ProteinID:
XP_045393192
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All DBs
Position
25:5759685..5783652
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AA seq
508 aa
AA seq
DB search
MYRTLRLLARSRCLLRAPASASAPGLSGAAVPPSWPPNAARMASQNSFRTEYDTFGELKV
PNDKYYGAQTVRSTMNFKIGGVTERMPIPVIKAFGILKRAAAEVNQDYGLDPKIANAIMK
AADEVAEGKLNDHFPLVVWQTGSGTQTNMNVNEVISNRAIEMLGGELGSKKPVHPNDHVN
KSQSSNDTFPTAMHIAAAVEVHEVLLPGLQKLHDALNAKSKEFAHIIKIGRTHTQDAVPL
TLGQEFGGYVQQVSYAMARIKAAMPRIYELAAGGTAVGTGLNTRIGFAEKVAAKVSTLTG
LPFVTAPNKFEALAAHDALVELSGAMNTTACSLMKIANDIRFLGSGPRSGLGELILPENE
PGSSIMPGKVNPTQCEAMTMVAAQVMGNHVAVTVGGSNGHFELNVFKPMMIKNVLQSARL
LGDVSVSFTENCVVGIQANTERINKLMNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTL
KETAIELGYLTAEQFDEWVKPKDMLGPK
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atgtaccgaacactccggctcctcgcgcgctcgcgttgcctcctgcgggctccagcctca
gcctcggctccgggcttgagtggcgcagccgtccccccatcctggcccccgaacgcggct
cgaatggcaagtcagaattctttccggacagaatatgatacatttggtgaactcaaggtc
ccaaatgataagtattatggtgcccagactgtgagatctacaatgaactttaagattgga
ggtgtgacggaacgcatgccaattccagttattaaagcttttggtatcttgaagcgagca
gccgctgaagtaaaccaggattatggtcttgatccaaagattgctaatgcaataatgaag
gcagcagatgaggtagctgaaggtaaattaaatgatcattttcctctcgtggtgtggcag
actggatcaggaacccagacaaatatgaatgtaaatgaagtcattagcaatagagcaatt
gaaatgttaggaggtgaacttggtagcaagaaacctgtgcatcccaatgatcatgttaat
aaaagccagagctcaaatgatactttccccacagcaatgcacattgctgccgcagtagaa
gttcatgaagtactgttaccaggactacagaagctacatgatgctctcaatgcaaaatcc
aaagagtttgcacacatcatcaaaattgggcgtactcatactcaggatgctgttccactt
actcttgggcaggaatttggtggttatgttcaacaagtgtcatatgcgatggcgagaata
aaagctgccatgccaagaatctatgagctcgcagctggaggcactgctgttggtactggt
ttaaatactagaattggctttgcagaaaaggttgctgcaaaagtgtctacactcacaggc
ttgccttttgtcactgctccaaataaatttgaagctctggctgctcatgatgctctggtt
gagctcagtggagccatgaacaccaccgcttgcagtctgatgaagatcgcaaatgatatt
cgttttctgggttctggtcctcggtcgggtctgggtgaactgatcttgcccgaaaatgaa
ccaggaagcagtatcatgccaggcaaggtgaaccccactcagtgtgaagcgatgaccatg
gttgcagcccaggtcatggggaatcatgtcgctgtgaccgtcggaggcagcaatggacat
ttcgagttgaatgttttcaagccaatgatgattaagaatgtgttacagtcggccaggctg
ctgggggatgtttcagtttccttcacagaaaactgtgtggtgggcatccaggccaacaca
gaaaggatcaacaagctaatgaatgagtctctaatgttggtgacagctctcaatcctcac
atagggtatgataaagcagcaaagattgctaagacagcacataaaaatggatcgacctta
aaggaaactgctattgaacttggctatctcacagcagagcagtttgatgagtgggtaaaa
cctaaggacatgctaggtccaaagtga
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